ATE540969T1 - Antimikrobielle hexapeptide - Google Patents
Antimikrobielle hexapeptideInfo
- Publication number
- ATE540969T1 ATE540969T1 AT06720369T AT06720369T ATE540969T1 AT E540969 T1 ATE540969 T1 AT E540969T1 AT 06720369 T AT06720369 T AT 06720369T AT 06720369 T AT06720369 T AT 06720369T AT E540969 T1 ATE540969 T1 AT E540969T1
- Authority
- AT
- Austria
- Prior art keywords
- pathogens
- hexapeptides
- dermatophytes
- positions
- typical
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title abstract 2
- 241001480043 Arthrodermataceae Species 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 2
- 230000037304 dermatophytes Effects 0.000 abstract 2
- 244000053095 fungal pathogen Species 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- IYKLZBIWFXPUCS-VIFPVBQESA-N (2s)-2-(naphthalen-1-ylamino)propanoic acid Chemical compound C1=CC=C2C(N[C@@H](C)C(O)=O)=CC=CC2=C1 IYKLZBIWFXPUCS-VIFPVBQESA-N 0.000 abstract 1
- 241000222122 Candida albicans Species 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 241001045770 Trichophyton mentagrophytes Species 0.000 abstract 1
- 241000223229 Trichophyton rubrum Species 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229940095731 candida albicans Drugs 0.000 abstract 1
- 125000001165 hydrophobic group Chemical group 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 244000045947 parasite Species 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65127005P | 2005-02-09 | 2005-02-09 | |
| PCT/US2006/004147 WO2006086321A2 (en) | 2005-02-09 | 2006-02-07 | Antimicrobial hexapeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE540969T1 true ATE540969T1 (de) | 2012-01-15 |
Family
ID=36793611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06720369T ATE540969T1 (de) | 2005-02-09 | 2006-02-07 | Antimikrobielle hexapeptide |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7407940B2 (de) |
| EP (1) | EP1853620B1 (de) |
| JP (1) | JP5335241B2 (de) |
| KR (1) | KR101306643B1 (de) |
| CN (1) | CN101155825B (de) |
| AT (1) | ATE540969T1 (de) |
| AU (1) | AU2006212922B2 (de) |
| CA (1) | CA2597191C (de) |
| DK (1) | DK1853620T3 (de) |
| ES (1) | ES2378242T3 (de) |
| PL (1) | PL1853620T3 (de) |
| SI (1) | SI1853620T1 (de) |
| WO (1) | WO2006086321A2 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070207112A1 (en) * | 2005-12-07 | 2007-09-06 | Grant Industries, Inc. | Anti-acne composition |
| IL172896A0 (en) * | 2005-12-29 | 2006-06-11 | Yeda Res & Dev | Cxcr4 inhibition |
| US8168181B2 (en) | 2006-02-13 | 2012-05-01 | Alethia Biotherapeutics, Inc. | Methods of impairing osteoclast differentiation using antibodies that bind siglec-15 |
| ES2397441T5 (es) | 2006-02-13 | 2022-09-14 | Daiichi Sankyo Co Ltd | Secuencias polinucleotídicas y polipeptídicas implicadas en el proceso de remodelación ósea |
| US8906859B2 (en) | 2006-11-10 | 2014-12-09 | Cera Therapeutics, Inc. | Uses of kappa opioid synthetic peptide amides |
| BRPI0718651B8 (pt) | 2006-11-10 | 2021-05-25 | Cara Therapeutics Inc | amidas peptídicas sintéticas |
| US7713937B2 (en) * | 2006-11-10 | 2010-05-11 | Cara Therapeutics, Inc. | Synthetic peptide amides and dimeric forms thereof |
| US8236766B2 (en) * | 2006-11-10 | 2012-08-07 | Cara Therapeutics, Inc. | Uses of synthetic peptide amides |
| US7842662B2 (en) | 2006-11-10 | 2010-11-30 | Cara Therapeutics, Inc. | Synthetic peptide amide dimers |
| JP2010516688A (ja) * | 2007-01-16 | 2010-05-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 抗菌ペプチド |
| KR100879220B1 (ko) | 2007-11-12 | 2009-01-19 | 아주대학교산학협력단 | 식물병원성 세균에 대한 항미생물 펩티드 ｋｃｍ２１ |
| KR100879221B1 (ko) | 2007-11-12 | 2009-01-19 | 아주대학교산학협력단 | 식물병원성 세균에 대한 항미생물 펩티드 ｋｒｓ２２ |
| GB0724951D0 (en) * | 2007-12-20 | 2008-01-30 | Lytix Biopharma As | Compounds |
| WO2009146885A2 (en) * | 2008-06-02 | 2009-12-10 | Spiderbiotech S.R.L. | Lipidated antibacterial peptides |
| GB0818072D0 (en) | 2008-10-02 | 2008-11-05 | Lytix Biopharma As | Compounds |
| GB0818074D0 (en) * | 2008-10-02 | 2008-11-05 | Lytix Biopharma As | Treatment of biofilms |
| GB0918579D0 (en) * | 2009-10-22 | 2009-12-09 | Imp Innovations Ltd | Gadd45beta targeting agents |
| EP2504351A4 (de) * | 2009-11-23 | 2013-10-30 | Palatin Technologies Inc | Melanocortin-1-rezeptor-spezifische lineare peptide |
| WO2013086003A1 (en) * | 2011-12-05 | 2013-06-13 | The Ohio State University | Antimicrobial agent, bacterial strain, biosynthesis, and methods of use |
| WO2013128003A1 (en) * | 2012-03-01 | 2013-09-06 | Novo Nordisk A/S | N-terminally modified oligopeptides and uses thereof |
| JP6268173B2 (ja) | 2012-07-19 | 2018-01-24 | 第一三共株式会社 | 抗Ｓｉｇｌｅｃ−１５抗体 |
| FR3002452B1 (fr) * | 2013-02-28 | 2016-02-12 | Dermaconcept Jmc | Composition dermatologique antimicrobienne topique |
| TWI577697B (zh) * | 2013-11-28 | 2017-04-11 | 國立清華大學 | 耐高鹽及抗蛋白之抗菌胜肽及其製造方法 |
| WO2016114390A1 (ja) | 2015-01-16 | 2016-07-21 | 株式会社マンダム | クレンジングローション、シート化粧料、及び美容方法 |
| US9738684B2 (en) | 2015-06-29 | 2017-08-22 | Council Of Scientific & Industrial Research | N-terminally modified linear and branched polyamine conjugated peptidomimetics as antimicrobials agents |
| KR101855170B1 (ko) * | 2015-11-18 | 2018-05-08 | (주)노바셀테크놀로지 | 신규 항균 펩타이드 및 그의 용도 |
| CN109942713A (zh) * | 2018-12-28 | 2019-06-28 | 广州医科大学 | 新型抗菌肽及其应用 |
| KR102170236B1 (ko) * | 2019-03-19 | 2020-10-29 | (주)노바셀테크놀로지 | 신규 다중 기능성 펩타이드 및 그의 용도 |
| US20220193244A1 (en) | 2019-05-06 | 2022-06-23 | Université De Genève | Antimicrobial tailored chitosan |
| CN110950932B (zh) * | 2020-01-09 | 2023-04-18 | 福州大学 | 一种修饰肽的制备及其应用 |
| KR102220323B1 (ko) * | 2020-05-15 | 2021-02-26 | (주)노바셀테크놀로지 | 신규 다중 기능성 펩타이드 및 그의 용도 |
| KR102429281B1 (ko) * | 2020-05-25 | 2022-08-05 | (주)노바셀테크놀로지 | 신규 안구건조증 치료용 약학적 조성물 |
| KR102486996B1 (ko) * | 2020-09-04 | 2023-01-10 | 서울대학교병원 | 펩타이드 및 이를 포함하는 피부 주름 개선용 조성물 및 대사성 질환 치료용 조성물 |
| CN111925422B (zh) * | 2020-09-17 | 2021-05-18 | 张雪山 | 抗菌肽及其在制备药物或化妆品中的应用 |
| CN113248572B (zh) * | 2021-04-30 | 2023-04-11 | 重庆理工大学 | 一种抗多重耐药菌环肽及其应用 |
| CZ309857B6 (cs) * | 2022-03-31 | 2023-12-20 | Contipro A.S. | Hexapeptid, kompozice zahrnující tento hexapeptid a jejich topické použití |
| CN116332777A (zh) * | 2023-02-20 | 2023-06-27 | 华中科技大学 | 二芳基苯甲胺类化合物、制备及作为载体合成多肽的应用 |
| CN116041422B (zh) * | 2023-03-31 | 2023-06-16 | 四川大学 | 自组装抗菌肽及其组合物、药物载体、载药体系和用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4520016A (en) * | 1980-06-17 | 1985-05-28 | Kabigen Ab | Bacteriolytic proteins |
| US4355104A (en) * | 1980-06-17 | 1982-10-19 | Kabigen Ab | Bacteriolytic proteins |
| CA1327311C (en) * | 1987-07-06 | 1994-03-01 | Jesse M. Jaynes | Therapeutic antimicrobial polypeptides, their use and methods for preparation |
| US5861478A (en) * | 1987-07-06 | 1999-01-19 | Helix Biomedix, Inc. | Lytic peptides |
| JP2962555B2 (ja) * | 1987-07-06 | 1999-10-12 | ヘリックス バイオメディックス，インコーポレイテッド | 溶菌ペプチドによる真核性病原体と新生物の抑制及び繊維芽細胞とリンパ球の刺激 |
| ATE189231T1 (de) | 1989-04-10 | 2000-02-15 | Helix Biomedix Inc | Lytische peptide, verwendung als wachstumsfördernde mittel und für infektionen und krebs |
| WO1992017195A1 (en) * | 1991-04-08 | 1992-10-15 | Magainin Pharmaceuticals, Inc. | Novel peptide compositions and uses therefor |
| AU7050294A (en) * | 1993-06-04 | 1995-01-03 | Demeter Biotechnologies, Ltd. | Method of treating pulmonary disease states with non-naturally occurring amphipathic peptides |
| US5955573A (en) * | 1993-06-04 | 1999-09-21 | Demegen, Inc. | Ubiquitin-lytic peptide fusion gene constructs, protein products deriving therefrom, and methods of making and using same |
| US5561107A (en) * | 1993-06-04 | 1996-10-01 | Demeter Biotechnologies, Ltd. | Method of enhancing wound healing by stimulating fibroblast and keratinocyte growth in vivo, utilizing amphipathic peptides |
| AU1086595A (en) * | 1993-11-08 | 1995-05-29 | Demeter Biotechnologies, Ltd. | Methylated lysine-rich lytic peptides and method of making same by reductive alkylation |
| AU693518B2 (en) * | 1994-01-18 | 1998-07-02 | Magainin Pharmaceuticals, Inc. | Ion-channel forming amphiphilic peptides having n-terminal modifications |
| US5789542A (en) * | 1994-04-22 | 1998-08-04 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Amphipathic peptides |
| IL114697A0 (en) | 1994-07-22 | 1995-11-27 | Demeter Biotech Ltd | Polypeptides comprising ubiquitin-lytic peptide fusion protein products deriving therefrom their preparation and use |
| AU727085B2 (en) * | 1995-07-20 | 2000-11-30 | Xoma Corporation | Anti-fungal peptides |
| AU1072897A (en) * | 1995-12-12 | 1997-07-03 | Karolinska Innovations Ab | Peptide binding the klvff-sequence of amyloid beta |
| US6566334B1 (en) * | 1997-02-06 | 2003-05-20 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Short amphipathic peptides with activity against bacteria and intracellular pathogens |
| US6635740B1 (en) * | 1997-03-27 | 2003-10-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Ligand/lytic peptide compositions and methods of use |
| AU2631501A (en) | 2000-01-06 | 2001-07-16 | Monsanto Technology Llc | Preparation of deallergenized proteins and permuteins |
| EP1292609A2 (de) * | 2000-06-16 | 2003-03-19 | Hercules Incorporated | Peptide, zusammesetzungen und verfahren zur behandlung von burkholderia cepacia |
| JP2004535392A (ja) * | 2001-05-04 | 2004-11-25 | ザ スクリプス リサーチ インスティチュート | 抗菌ペプチドおよび組成物 |
-
2006
- 2006-02-07 CA CA2597191A patent/CA2597191C/en active Active
- 2006-02-07 ES ES06720369T patent/ES2378242T3/es active Active
- 2006-02-07 EP EP06720369A patent/EP1853620B1/de active Active
- 2006-02-07 AT AT06720369T patent/ATE540969T1/de active
- 2006-02-07 PL PL06720369T patent/PL1853620T3/pl unknown
- 2006-02-07 JP JP2007555158A patent/JP5335241B2/ja active Active
- 2006-02-07 WO PCT/US2006/004147 patent/WO2006086321A2/en active Application Filing
- 2006-02-07 KR KR1020077020308A patent/KR101306643B1/ko active IP Right Grant
- 2006-02-07 AU AU2006212922A patent/AU2006212922B2/en not_active Ceased
- 2006-02-07 DK DK06720369.5T patent/DK1853620T3/da active
- 2006-02-07 CN CN200680011180.7A patent/CN101155825B/zh active Active
- 2006-02-07 SI SI200631248T patent/SI1853620T1/sl unknown
- 2006-02-08 US US11/350,192 patent/US7407940B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US7407940B2 (en) | 2008-08-05 |
| WO2006086321A3 (en) | 2007-02-22 |
| JP2008537537A (ja) | 2008-09-18 |
| CA2597191C (en) | 2014-04-01 |
| SI1853620T1 (sl) | 2012-03-30 |
| EP1853620B1 (de) | 2012-01-11 |
| KR20070107748A (ko) | 2007-11-07 |
| JP5335241B2 (ja) | 2013-11-06 |
| US20060229252A1 (en) | 2006-10-12 |
| DK1853620T3 (da) | 2012-03-26 |
| CN101155825B (zh) | 2014-11-26 |
| ES2378242T3 (es) | 2012-04-10 |
| CN101155825A (zh) | 2008-04-02 |
| AU2006212922A1 (en) | 2006-08-17 |
| CA2597191A1 (en) | 2006-08-17 |
| PL1853620T3 (pl) | 2012-07-31 |
| EP1853620A2 (de) | 2007-11-14 |
| KR101306643B1 (ko) | 2013-09-12 |
| AU2006212922B2 (en) | 2011-04-21 |
| WO2006086321A2 (en) | 2006-08-17 |
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