CN101129762A - Traditional Chinese medicine preparation for treating diabetes cardiac disease - Google Patents
Traditional Chinese medicine preparation for treating diabetes cardiac disease Download PDFInfo
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- CN101129762A CN101129762A CNA2007101209279A CN200710120927A CN101129762A CN 101129762 A CN101129762 A CN 101129762A CN A2007101209279 A CNA2007101209279 A CN A2007101209279A CN 200710120927 A CN200710120927 A CN 200710120927A CN 101129762 A CN101129762 A CN 101129762A
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Abstract
The invention relates to a Chinese medicament for treating diabetic heart disease which is prepared from more than ten kinds of Chinese medicinal herbs including radix adenophorae, scrophularia root, dried rehmannia root and arborviate seed. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of diabetic cardiopathy, is that a kind of diabetic cardiopathy for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic coronary artery disease means coronary atherosclerosis, lumen of vessels is narrow or inaccessible to cause myocardial ischemia, anoxia and the heart change that causes, with the functional change of coronary artery (spasm), be referred to as coronary heart disease (abbreviation coronary heart disease), be called ischemic heart desease again.Coronary heart disease is the diabetes most common complication, and U.S.'s diabetes study is reported in recent years, and diabetic history is the person more than 6.5 years, and the incidence rate of coronary heart disease is 12%.Framingram finds that diabetes complicated coronary heart disease is 3 times of non-diabetic person, finds that from postmortem glycosuria patient coronary atherosclerosis is 4 times of non-diabetic person.Concord Hospital data prompting coronary heart disease prevalence is 38%, Beijing Hospital to the concurrent coronary heart disease of senile diabetes postmortem result up to 82%.Have 50% patient not have classical angina, 35.5% acute myocardial infarction person is painless type, and its case fatality rate is 50% in NIDDM, is 25% in IDDM.Diabetic coronary artery disease is to be factor such as this hold concurrently folder expectorant is turbid, blood stasis, cold coagulation and cause reality with void, the disease of simulataneous insufficiency and excessive with the deficiency of YIN in diabetes.By its different clinical manifestation, be divided into coronary heart disease (thoracic obstruction) and acute myocardial infarction (angina pectoris) and carry out dialectical opinion and control.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as qi stagnation and blood stasis type, type of stagnation of turbid phlegm and blood stasis, cold blood stasis type, heart arteries and veins blood stasis blocking type, sudden depletion of heart-YANG type, kidney-yang deficiency type clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic cardiopathy.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.5～6 parts of 1.5～6 parts of Radix Salviae Miltiorrhizaes of 1.5～6 parts of Radix Rehmanniae of Radix Ophiopogonis
1.0～4 parts in 1.0～4 parts of Poria of 1.0～4 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
0.1～2 part of 1.0～4 portions of Radix Scrophulariae of 1.0～4 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
0.1～2 part of 0.1～2 part of Radix Polygalae of 0.1～2 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
The weight proportion of each crude drug of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of 2.5～3.5 parts of Radix Rehmanniae of Radix Ophiopogonis
1.5～2.5 parts in 1.5～2.5 parts of Poria of 1.5～2.5 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
0.5～1.5 part of 1.5～2.5 portions of Radix Scrophulariae of 1.5～2.5 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
0.5～1.5 part of 0.5～1.5 part of Radix Polygalae of 0.5～1.5 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
The weight proportion of each crude drug of optimum formula of the present invention is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Radix Rehmanniae of Radix Ophiopogonis
2 parts in 2 parts of Poria of 2 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
1 part of 2 portions of Radix Scrophulariae of 2 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
1 part of 1 part of Radix Polygalae of 1 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of Radix Adenophorae (Radix Glehniae) property of medicine is slightly cold.Attach to the lung and stomach meridians.Has replenishing YIN and removing heat, moistening the lung and resolving phlegm, the effect of reinforcing stomach reg fluid.Can treat deficiency of YIN chronic cough, the consumptive disease expectorant blood of coughing, cough caused by dryness expectorant is few, the deficiency-heat sore throat, Tianjin wound is thirsty etc.(the 1626th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Pseudostellariae property of medicine is slightly cold.Return spleen, lung meridian.Has supplementing QI for promoting the production of body fluid, the effect of spleen reinforcing lung moistening.It is tired to treat insufficiency of the spleen body, inappetence, and impairment of both QI and YIN, dry cough expectorant is few, and spontaneous perspiration is breathed hard, and interior-heat is thirsty, the neurasthenia, palpitation and insomnia, dizzy forgetful, children's's summer fever etc.(the 534th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Glycyrrhizae Preparata property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Platycladi property of medicine is sweet, and is flat.GUIXIN, kidney, large intestine channel.Has tranquilizing by nourishing the heart, arresting sweating, the effect of loosening bowel to relieve constipation.Can treat the palpitation with fear palpitation with a distress feeling, insomnia forgetfulness, night sweat, dryness of the intestine constipation etc.(the 2238th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Schisandrae Chinensis property of medicine, warm in nature.Return lung, the heart, kidney channel.It is astringent or styptic treatment for spontaneous sweating to have convergence, supplementing QI for promoting the production of body fluid, the effect of mind tranquilizing and the heart calming.Can treat the chronic cough dyspnea due to deficiency, emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, palpitation and insomnia etc.(the 520th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Sophorae Flavescentis property of medicine hardship, cold.GUIXIN, lung, kidney, large intestine channel.Has heat clearing and damp drying, the effect of wind dispelling insecticide.Can treat damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.(the 1758th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Polygalae property of medicine suffering, hardship, tepor.GUIXIN, lung, kidney channel.Have mind tranquilizing and the heart calming, eliminate the phlegm and have one's ideas straightened out, the effect of removing toxic substances and promoting subsidence of swelling.Can treat irritability, the palpitation with fear insomnia, forgetful, infantile convulsion, cough with copious phlegm, carbuncle carbuncle on the back, breast swell and pain etc.(the 1436th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Ophiopogonis, Radix Rehmanniae and Radix Salviae Miltiorrhizae; With Radix Adenophorae (Radix Glehniae), Radix Pseudostellariae, Poria, Radix Glycyrrhizae Preparata and Semen Platycladi is ministerial drug; With Radix Scrophulariae, Fructus Schisandrae Chinensis, Radix Sophorae Flavescentis and Radix Polygalae is adjuvant.All medicines are harmonious, and are total to the tool nourishing YIN and clearing away fire, the effect of tranquilizing by nourishing the heart.The treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment diabetic cardiopathy of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic cardiopathy, and the prevention of diabetic cardiopathy is also had good effect, and the treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic cardiopathy; Treatment diabetic cardiopathy patient 26 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.12 examples of fully recovering account for 46.15%, and 10 examples that take a turn for the better account for 38.46%, and invalid 4 examples account for 15.38%, and total effective rate reaches 84.61%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Radix Rehmanniae of Radix Ophiopogonis
2 parts in 2 parts of Poria of 2 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
1 part of 2 portions of Radix Scrophulariae of 2 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
1 part of 1 part of Radix Polygalae of 1 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic cardiopathy that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.
Claims (3)
1. Chinese medicine preparation for the treatment of diabetic cardiopathy is characterized in that it is made by following raw materials by weight proportions:
1.5～6 parts of 1.5～6 parts of Radix Salviae Miltiorrhizaes of 1.5～6 parts of Radix Rehmanniae of Radix Ophiopogonis
1.0～4 parts in 1.0～4 parts of Poria of 1.0～4 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
0.1～2 part of 1.0～4 portions of Radix Scrophulariae of 1.0～4 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
0.1～2 part of 0.1～2 part of Radix Polygalae of 0.1～2 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
2. a kind of Chinese medicine preparation for the treatment of diabetic cardiopathy according to claim 1, wherein the weight proportion of each crude drug is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of 2.5～3.5 parts of Radix Rehmanniae of Radix Ophiopogonis
1.5～2.5 parts in 1.5～2.5 parts of Poria of 1.5～2.5 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
0.5～1.5 part of 1.5～2.5 portions of Radix Scrophulariae of 1.5～2.5 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
0.5～1.5 part of 0.5～1.5 part of Radix Polygalae of 0.5～1.5 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
3. a kind of Chinese medicine preparation for the treatment of diabetic cardiopathy according to claim 1, wherein the weight proportion of each crude drug is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Radix Rehmanniae of Radix Ophiopogonis
2 parts in 2 parts of Poria of 2 parts of Radix Pseudostellariaes of Radix Adenophorae (Radix Glehniae)
1 part of 2 portions of Radix Scrophulariae of 2 parts of Semen Platycladi of Radix Glycyrrhizae Preparata
1 part of 1 part of Radix Polygalae of 1 part of Radix Sophorae Flavescentis of Fructus Schisandrae Chinensis.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101209279A CN101129762A (en) | 2007-08-29 | 2007-08-29 | Traditional Chinese medicine preparation for treating diabetes cardiac disease |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101209279A CN101129762A (en) | 2007-08-29 | 2007-08-29 | Traditional Chinese medicine preparation for treating diabetes cardiac disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843831B (en) * | 2009-10-16 | 2011-06-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic cardiopathy |
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- 2007-08-29 CN CNA2007101209279A patent/CN101129762A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843831B (en) * | 2009-10-16 | 2011-06-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic cardiopathy |
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Open date: 20080227 |