CN101112514A - Chinese medicine preparation for treating diabetic cardiac disease - Google Patents
Chinese medicine preparation for treating diabetic cardiac disease Download PDFInfo
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- CN101112514A CN101112514A CNA200710120925XA CN200710120925A CN101112514A CN 101112514 A CN101112514 A CN 101112514A CN A200710120925X A CNA200710120925X A CN A200710120925XA CN 200710120925 A CN200710120925 A CN 200710120925A CN 101112514 A CN101112514 A CN 101112514A
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Abstract
The present invention relates to a traditional Chinese medicine preparation for treating diabetic heart disease, which takes more than 10 Chinese herbal medicines of motherwort herb, pepperweed seed, agaric, dwarf lilyturf tuber etc. as the raw materials. The present invention has the effects of benefiting qi, nourishing heart, inducing diuresis and removing edema. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine preparation for treating diabetic heart disease. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.
Description
Technical field
The present invention relates to treat a kind of Chinese medicine preparation of diabetic cardiopathy, is that a kind of diabetic cardiopathy for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic coronary artery disease means coronary atherosclerosis, lumen of vessels is narrow or inaccessible to cause myocardial ischemia, anoxia and the heart change that causes, with the functional change of coronary artery (spasm), be referred to as coronary heart disease (abbreviation coronary heart disease), be called ischemic heart desease again.Coronary heart disease is the diabetes most common complication, and U.S.'s diabetes study is reported in recent years, and diabetic history is the person more than 6.5 years, and the incidence rate of coronary heart disease is 12%.Framingram finds that diabetes complicated coronary heart disease is 3 times of non-diabetic person, finds that from postmortem glycosuria patient coronary atherosclerosis is 4 times of non-diabetic person.Concord Hospital data prompting coronary heart disease prevalence is 38%, Beijing Hospital to the concurrent coronary heart disease of senile diabetes postmortem result up to 82%.Have 50% patient not have classical angina, 35.5% acute myocardial infarction person is painless type, and its case fatality rate is 50% in NIDDM, is 25% in IDDM.Diabetic coronary artery disease is to be factor such as this hold concurrently folder expectorant is turbid, blood stasis, cold coagulation and cause reality with void, the disease of simulataneous insufficiency and excessive with the deficiency of YIN in diabetes.By its different clinical manifestation, be divided into coronary heart disease (thoracic obstruction) and acute myocardial infarction (angina pectoris) and carry out dialectical opinion and control.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as qi stagnation and blood stasis type, type of stagnation of turbid phlegm and blood stasis, cold blood stasis type, heart arteries and veins blood stasis blocking type, sudden depletion of heart-YANG type, kidney-yang deficiency type clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic cardiopathy.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.5～6 parts of 1.5～6 parts of Radix Salviae Miltiorrhizaes of 1.5～6 parts of Radix Astragali of Polyporus
1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.0～4 portions of Rhizoma Alismatis of Radix Codonopsis
0.1～2 part of 1.0～4 portions of Semen Plantaginis of 1.0～4 parts of Herba Leonuris of Radix Angelicae Sinensis
0.1～1 part of 0.1～2 part of Semen Lepidii (Semen Descurainiae) of 0.1～2 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
The weight proportion of each crude drug of optimization formula of the present invention is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of 2.5～3.5 parts of Radix Astragali of Polyporus
1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 1.5～2.5 portions of Rhizoma Alismatis of Radix Codonopsis
0.5～1.5 part of 1.5～2.5 portions of Semen Plantaginis of 1.5～2.5 parts of Herba Leonuris of Radix Angelicae Sinensis
0.3～0.7 part of 0.5～1.5 part of Semen Lepidii (Semen Descurainiae) of 0.5～1.5 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
The weight proportion of each crude drug of optimum formula of the present invention is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Radix Astragali of Polyporus
2 parts of 2 parts of Radix Ophiopogonis of 2 portions of Rhizoma Alismatis of Radix Codonopsis
1 part of 2 portions of Semen Plantaginis of 2 parts of Herba Leonuris of Radix Angelicae Sinensis
0.5 part of 1 part of Semen Lepidii (Semen Descurainiae) of 1 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
Drug action mechanism among the present invention is as follows:
The Polyporus property of medicine is sweet, light, and is flat.Return spleen, kidney, urinary bladder channel.Effect with promoting diuresis to eliminate damp pathogen.Can treat dysuria, the edema distension is had loose bowels, stranguria with turbid discharge, leukorrhagia, beriberi edema etc.(the 3060th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and half.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Semen Plantaginis property of medicine is sweet, light, is slightly cold.Return lung, liver, kidney, urinary bladder channel.Have heat clearing away, diuresis makes eye bright, the expectorant effect.Can treat urinary obstruction, stranguria with turbid discharge, leukorrhagia, edema, the heat-damp in summer dysentery, conjunctival congestion is hidden from view, and the expectorant heat syndrome cough is breathed heavily etc.(the 539th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Ramulus Cinnamomi property of medicine suffering, sweet, temperature.Return bladder, the heart, lung meridian.Has expelling cold and relieving exterior syndrome, warming the meridian, the effect of activating yang.Can treat exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea ， mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria etc.(the 2522nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Schisandrae Chinensis property of medicine, warm in nature.Return lung, the heart, kidney channel.It is astringent or styptic treatment for spontaneous sweating to have convergence, supplementing QI for promoting the production of body fluid, the effect of mind tranquilizing and the heart calming.Can treat the chronic cough dyspnea due to deficiency, emission, frequent urination and enuresis, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, palpitation and insomnia etc.(the 520th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Lepidii (Semen Descurainiae) property of medicine suffering, hardship, cold.Return lung, bladder, large intestine channel.Has eliminating pathogen from the lung for relieving asthma, the effect of inducing diuresis to remove edema.Sputum be can treat and the dyspnea and cough with excessive sputum of lung, lung abscess, breast abdomen hydrops, edema, carbuncle malignant boil, scrofula tuberculosis etc. stopped up.(the 777th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Polyporus, Radix Astragali and Radix Salviae Miltiorrhizae; With Radix Codonopsis, Semen Lepidii (Semen Descurainiae), Rhizoma Alismatis, Radix Angelicae Sinensis, Radix Ophiopogonis and Herba Leonuri is ministerial drug; With Semen Plantaginis, Ramulus Cinnamomi and Fructus Schisandrae Chinensis is adjuvant.All medicines are harmonious, and are total to the tool Qi-benefiting and heart-nourishing, the effect of inducing diuresis to remove edema.The treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment diabetic cardiopathy of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic cardiopathy, and the prevention of diabetic cardiopathy is also had good effect, and the treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic cardiopathy; Treatment diabetic cardiopathy patient 27 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Two months is a course of treatment, take continuously three the course of treatment observe the curative effect.13 examples of fully recovering account for 48.15%, and 10 examples that take a turn for the better account for 37.04%, and invalid 4 examples account for 14.81%, and total effective rate reaches 85.19%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Radix Astragali of Polyporus
2 parts of 2 parts of Radix Ophiopogonis of 2 portions of Rhizoma Alismatis of Radix Codonopsis
1 part of 2 portions of Semen Plantaginis of 2 parts of Herba Leonuris of Radix Angelicae Sinensis
0.5 part of 1 part of Semen Lepidii (Semen Descurainiae) of 1 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic cardiopathy that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Two months is a course of treatment.
Claims (3)
1. a kind of Chinese medicine preparation of treatment diabetic cardiopathy is characterized in that it is made by following raw materials by weight proportions:
1.5～6 parts of 1.5～6 parts of Radix Salviae Miltiorrhizaes of 1.5～6 parts of Radix Astragali of Polyporus
1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.0～4 portions of Rhizoma Alismatis of Radix Codonopsis
0.1～2 part of 1.0～4 portions of Semen Plantaginis of 1.0～4 parts of Herba Leonuris of Radix Angelicae Sinensis
0.1～1 part of 0.1～2 part of Semen Lepidii (Semen Descurainiae) of 0.1～2 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
2. a kind of Chinese medicine preparation of treatment diabetic cardiopathy according to claim 1, wherein the weight proportion of each crude drug is:
2.5～3.5 parts of 2.5～3.5 parts of Radix Salviae Miltiorrhizaes of 2.5～3.5 parts of Radix Astragali of Polyporus
1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 1.5～2.5 portions of Rhizoma Alismatis of Radix Codonopsis
0.5～1.5 part of 1.5～2.5 portions of Semen Plantaginis of 1.5～2.5 parts of Herba Leonuris of Radix Angelicae Sinensis
0.3～0.7 part of 0.5～1.5 part of Semen Lepidii (Semen Descurainiae) of 0.5～1.5 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
3. a kind of Chinese medicine preparation of treatment diabetic cardiopathy according to claim 1, wherein the weight proportion of each crude drug is:
3 parts of 3 parts of Radix Salviae Miltiorrhizaes of 3 parts of Radix Astragali of Polyporus
2 parts of 2 parts of Radix Ophiopogonis of 2 portions of Rhizoma Alismatis of Radix Codonopsis
1 part of 2 portions of Semen Plantaginis of 2 parts of Herba Leonuris of Radix Angelicae Sinensis
0.5 part of 1 part of Semen Lepidii (Semen Descurainiae) of 1 part of Fructus Schisandrae Chinensis of Ramulus Cinnamomi.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200710120925XA CN101112514A (en) | 2007-08-29 | 2007-08-29 | Chinese medicine preparation for treating diabetic cardiac disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA200710120925XA CN101112514A (en) | 2007-08-29 | 2007-08-29 | Chinese medicine preparation for treating diabetic cardiac disease |
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| CN101112514A true CN101112514A (en) | 2008-01-30 |
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| CNA200710120925XA Pending CN101112514A (en) | 2007-08-29 | 2007-08-29 | Chinese medicine preparation for treating diabetic cardiac disease |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091163A (en) * | 2010-12-06 | 2011-06-15 | 济南金鼎信息技术有限公司 | Chinese medicine composition for treating diabetic heart disease |
| CN101843831B (en) * | 2009-10-16 | 2011-06-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic cardiopathy |
-
2007
- 2007-08-29 CN CNA200710120925XA patent/CN101112514A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101843831B (en) * | 2009-10-16 | 2011-06-29 | 北京绿源求证科技发展有限责任公司 | Chinese medicament for treating diabetic cardiopathy |
| CN102091163A (en) * | 2010-12-06 | 2011-06-15 | 济南金鼎信息技术有限公司 | Chinese medicine composition for treating diabetic heart disease |
| CN102091163B (en) * | 2010-12-06 | 2012-02-01 | 李凤婷 | Chinese medicine composition for treating diabetic heart disease |
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Open date: 20080130 |