CN101112593A - Chinese traditional medicine composition for treating diabetic cardiac disease - Google Patents
Chinese traditional medicine composition for treating diabetic cardiac disease Download PDFInfo
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- CN101112593A CN101112593A CNA2007101208914A CN200710120891A CN101112593A CN 101112593 A CN101112593 A CN 101112593A CN A2007101208914 A CNA2007101208914 A CN A2007101208914A CN 200710120891 A CN200710120891 A CN 200710120891A CN 101112593 A CN101112593 A CN 101112593A
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Abstract
The present invention relates to a traditional Chinese medicine composition for treating diabetic heart disease, which takes more than 10 Chinese herbal medicines of snakegourd fruit, pilose Asiabell root, roasted liquoric root, prepared pinellia tuber etc. as the raw materials. The present invention has the effects of activating yang with medicines pungent pungent in taste and warm in property, dredging arthralgia and dispersing cold. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine composition for treating diabetic heart disease. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of diabetic cardiopathy, is that a kind of diabetic cardiopathy for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic coronary artery disease means coronary atherosclerosis, lumen of vessels is narrow or inaccessible to cause myocardial ischemia, anoxia and the heart change that causes, with the functional change of coronary artery (spasm), be referred to as coronary heart disease (abbreviation coronary heart disease), be called ischemic heart desease again.Coronary heart disease is the diabetes most common complication, and U.S.'s diabetes study is reported in recent years, and diabetic history is the person more than 6.5 years, and the incidence rate of coronary heart disease is 12%.Framingram finds that diabetes complicated coronary heart disease is 3 times of non-diabetic person, finds that from postmortem glycosuria patient coronary atherosclerosis is 4 times of non-diabetic person.Concord Hospital data prompting coronary heart disease prevalence is 38%, Beijing Hospital to the concurrent coronary heart disease of senile diabetes postmortem result up to 82%.Have 50% patient not have classical angina, 35.5% acute myocardial infarction person is painless type, and its case fatality rate is 50% in NIDDM, is 25% in IDDM.Diabetic coronary artery disease is to be factor such as this hold concurrently folder expectorant is turbid, blood stasis, cold coagulation and cause reality with void, the disease of simulataneous insufficiency and excessive with the deficiency of YIN in diabetes.By its different clinical manifestation, be divided into coronary heart disease (thoracic obstruction) and acute myocardial infarction (angina pectoris) and carry out dialectical opinion and control.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as qi stagnation and blood stasis type, type of stagnation of turbid phlegm and blood stasis, cold blood stasis type, heart arteries and veins blood stasis blocking type, sudden depletion of heart-YANG type, kidney-yang deficiency type clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of diabetic cardiopathy.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.5～6 parts of Fructus Aurantiis of Fructus Trichosanthis
1.0～4 parts of 1.0～4 parts of Radix Glycyrrhizae Preparatas of 1.5～6 parts of Poria of Radix Codonopsis
1.5～6 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 0.1～2 part of Pericarpium Citri Reticulatae for 0.1～2 part
0.1～1 part of 0.1～2 part of Rhizoma Pinelliae Preparatum of 1.0～4 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
1.0～4 parts of Radix Angelicae Sinensis.
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 2.5～3.5 parts of Fructus Aurantiis of Fructus Trichosanthis
1.5～2.5 parts of 1.5～2.5 parts of Radix Glycyrrhizae Preparatas of 2.5～3.5 parts of Poria of Radix Codonopsis
2.5～3.5 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 0.5～1.5 part of Pericarpium Citri Reticulatae for 0.5～1.5 part
0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae Preparatum of 1.5～2.5 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
1.5～2.5 parts of Radix Angelicae Sinensis.
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of Radix Ophiopogonis of 3 parts of Fructus Aurantiis of Fructus Trichosanthis
2 parts of 2 parts of Radix Glycyrrhizae Preparatas of 3 parts of Poria of Radix Codonopsis
3 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 1 part of Pericarpium Citri Reticulatae for 1 part
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
2 parts of Radix Angelicae Sinensis.
Drug action mechanism among the present invention is as follows:
Sweet, the little hardship of the Fructus Trichosanthis property of medicine, cold.Return lung, stomach, large intestine channel.Has the heat clearing away expectorant, relieving stuffiness of the chest by dispersing aggregation of pathogens, the effect of moisturizing laxation.Can treat pulmonary carcinoma, gastric cancer, cancer of pancreas, breast carcinoma etc.It is thick to be used for the turbid Huang of cough due to lung-heat's expectorant, obstruction of qi in the chest and cardialgia, and the blocked-up chest feeling of fullness, acute mastitis, lung abscess, acute appendicitis swells and ache, constipation etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 483rd page).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Bulbus Allii Macrostemonis property of medicine suffering, hardship, temperature.Return lung, the heart, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of activating YANG and eliminating stagnation.Can treat the thorough back of the body of obstruction of qi in the chest and cardialgia, breast gastral cavity painful abdominal mass is vexed, cough with copious phlegm, epigastric pain, let out after the dysentery heavy, leucorrhea, furuncle carbuncle etc.(the 3721st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Glycyrrhizae Preparata property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Ramulus Cinnamomi property of medicine suffering, sweet, temperature.Return bladder, the heart, lung meridian.Has expelling cold and relieving exterior syndrome, warming the meridian, the effect of activating yang.Can treat exterior syndrome due to wind-cold, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea ， mass in the abdomen caking, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria etc.(the 2522nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fry Pericarpium Citri Reticulatae property of medicine suffering, hardship, temperature.Return spleen, stomach, lung meridian.Having in the accent of regulating the flow of vital energy stopping nausea and vomiting by lowering the adverse flow of QI, the effect of drying dampness to eliminate phlegm.It is full vexed to treat chest and diaphragm, abdominal distention, anorexia, vomiting, hiccup; Cough with copious phlegm.Acute mastitis from the beginning of etc.(the 1668th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea ， mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Pinelliae Preparatum property of medicine suffering, temperature, poisonous.Return spleen, stomach, lung meridian.Has drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, the effect of dissolving lump and resolving mass.Can treat the cough with asthma abundant expectoration, vomiting regurgitation, feeling of oppression and fullness in the chest and epigastrium, pain is dizzy, uneasy sleeping at night, goiter sucutaneous nodule, swollen ulcer drug etc.(the 1073rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Fructus Trichosanthis, Radix Codonopsis and Radix Salviae Miltiorrhizae; With Bulbus Allii Macrostemonis, Rhizoma Pinelliae Preparatum, Radix Angelicae Sinensis, Radix Ophiopogonis, Fructus Aurantii, Poria and Radix Glycyrrhizae Preparata is ministerial drug; With Ramulus Cinnamomi, stir-fry Pericarpium Citri Reticulatae and Radix Curcumae is adjuvant.All medicines are harmonious, and are total to the tool activating YANG with pungent and warm drugs, open the effect of numbness cold expelling.The treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment diabetic cardiopathy of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic cardiopathy, and the prevention of diabetic cardiopathy is also had good effect, and the treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic cardiopathy; Treatment diabetic cardiopathy patient 28 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.14 examples of fully recovering account for 50%, and 9 examples that take a turn for the better account for 32.14%, and invalid 5 examples account for 17.86%, and total effective rate reaches 82.14%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of Radix Ophiopogonis of 3 parts of Fructus Aurantiis of Fructus Trichosanthis
2 parts of 2 parts of Radix Glycyrrhizae Preparatas of 3 parts of Poria of Radix Codonopsis
3 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 1 part of Pericarpium Citri Reticulatae for 1 part
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
2 parts of Radix Angelicae Sinensis.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic cardiopathy that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.
Claims (3)
1. Chinese medicine composition for the treatment of diabetic cardiopathy is characterized in that it is made by the following weight proportion raw material:
1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.5～6 parts of Fructus Aurantiis of Fructus Trichosanthis
1.0～4 parts of 1.0～4 parts of Radix Glycyrrhizae Preparatas of 1.5～6 parts of Poria of Radix Codonopsis
1.5～6 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 0.1～2 part of Pericarpium Citri Reticulatae for 0.1～2 part
0.1～1 part of 0.1～2 part of Rhizoma Pinelliae Preparatum of 1.0～4 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
1.0～4 parts of Radix Angelicae Sinensis.
2. a kind of Chinese medicine composition for the treatment of diabetic cardiopathy according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 2.5～3.5 parts of Fructus Aurantiis of Fructus Trichosanthis
1.5～2.5 parts of 1.5～2.5 parts of Radix Glycyrrhizae Preparatas of 2.5～3.5 parts of Poria of Radix Codonopsis
2.5～3.5 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 0.5～1.5 part of Pericarpium Citri Reticulatae for 0.5～1.5 part
0.3～0.7 part of 0.5～1.5 part of Rhizoma Pinelliae Preparatum of 1.5～2.5 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
1.5～2.5 parts of Radix Angelicae Sinensis.
3. a kind of Chinese medicine composition for the treatment of diabetic cardiopathy according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of Radix Ophiopogonis of 3 parts of Fructus Aurantiis of Fructus Trichosanthis
2 parts of 2 parts of Radix Glycyrrhizae Preparatas of 3 parts of Poria of Radix Codonopsis
3 parts of Ramulus Cinnamomi of Radix Salviae Miltiorrhizae are fried 1 part of Pericarpium Citri Reticulatae for 1 part
0.5 part of 1 part of Rhizoma Pinelliae Preparatum of 2 portions of Radix Curcumaes of Bulbus Allii Macrostemonis
2 parts of Radix Angelicae Sinensis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101208914A CN101112593A (en) | 2007-08-29 | 2007-08-29 | Chinese traditional medicine composition for treating diabetic cardiac disease |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101208914A CN101112593A (en) | 2007-08-29 | 2007-08-29 | Chinese traditional medicine composition for treating diabetic cardiac disease |
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| CN101112593A true CN101112593A (en) | 2008-01-30 |
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| CNA2007101208914A Pending CN101112593A (en) | 2007-08-29 | 2007-08-29 | Chinese traditional medicine composition for treating diabetic cardiac disease |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104605269A (en) * | 2015-03-04 | 2015-05-13 | 段英兰 | Healthy porridge conducive to people with diabetes and preparation method thereof |
| CN105687836A (en) * | 2016-02-25 | 2016-06-22 | 太和县人民医院 | Qi tonifying and yang warming paralysis eliminating soup and preparing method thereof |
| CN113694130A (en) * | 2021-09-26 | 2021-11-26 | 辽宁中医药大学 | A Chinese medicinal composition for treating diabetic cardiac lesion and preparation method thereof |
-
2007
- 2007-08-29 CN CNA2007101208914A patent/CN101112593A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104605269A (en) * | 2015-03-04 | 2015-05-13 | 段英兰 | Healthy porridge conducive to people with diabetes and preparation method thereof |
| CN105687836A (en) * | 2016-02-25 | 2016-06-22 | 太和县人民医院 | Qi tonifying and yang warming paralysis eliminating soup and preparing method thereof |
| CN113694130A (en) * | 2021-09-26 | 2021-11-26 | 辽宁中医药大学 | A Chinese medicinal composition for treating diabetic cardiac lesion and preparation method thereof |
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Open date: 20080130 |