CN101112595A - Chinese patent medicine for treating diabetic cardiac disease - Google Patents
Chinese patent medicine for treating diabetic cardiac disease Download PDFInfo
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- CN101112595A CN101112595A CNA2007101209300A CN200710120930A CN101112595A CN 101112595 A CN101112595 A CN 101112595A CN A2007101209300 A CNA2007101209300 A CN A2007101209300A CN 200710120930 A CN200710120930 A CN 200710120930A CN 101112595 A CN101112595 A CN 101112595A
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Abstract
The present invention relates to a Chinese traditional patent medicine for treating diabetic heart disease, which takes more than 10 Chinese herbal medicines of alcohol processed Chinese angelica, salvia miltiorrhiza, yanhusuo, raw nutgrass galingale rhizome etc. as the raw materials. The invention has the effects of activating blood circulation, removing blood stasis, dredging collaterals and stopping pain. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the Chinese traditional patent medicine for treating diabetic heart disease. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine for the treatment of diabetic cardiopathy, is that a kind of diabetic cardiopathy for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic coronary artery disease means coronary atherosclerosis, lumen of vessels is narrow or inaccessible to cause myocardial ischemia, anoxia and the heart change that causes, with the functional change of coronary artery (spasm), be referred to as coronary heart disease (abbreviation coronary heart disease), be called ischemic heart desease again.Coronary heart disease is the diabetes most common complication, and U.S.'s diabetes study is reported in recent years, and diabetic history is the person more than 6.5 years, and the incidence rate of coronary heart disease is 12%.Framingram finds that diabetes complicated coronary heart disease is 3 times of non-diabetic person, finds that from postmortem glycosuria patient coronary atherosclerosis is 4 times of non-diabetic person.Concord Hospital data prompting coronary heart disease prevalence is 38%, Beijing Hospital to the concurrent coronary heart disease of senile diabetes postmortem result up to 82%.Have 50% patient not have classical angina, 35.5% acute myocardial infarction person is painless type, and its case fatality rate is 50% in NIDDM, is 25% in IDDM.Diabetic coronary artery disease is to be factor such as this hold concurrently folder expectorant is turbid, blood stasis, cold coagulation and cause reality with void, the disease of simulataneous insufficiency and excessive with the deficiency of YIN in diabetes.By its different clinical manifestation, be divided into coronary heart disease (thoracic obstruction) and acute myocardial infarction (angina pectoris) and carry out dialectical opinion and control.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as qi stagnation and blood stasis type, type of stagnation of turbid phlegm and blood stasis, cold blood stasis type, heart arteries and veins blood stasis blocking type, sudden depletion of heart-YANG type, kidney-yang deficiency type clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of diabetic cardiopathy.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.0～4.0 parts of 1.0～4 parts of living Rhizoma Cyperis of 1.5～6 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
0.1～2.0 part of 1.0～4 parts of Fructus Aurantii (parched) of 1.5～6 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
0.1～2.0 part of 1.0～4 parts of Radix Glycyrrhizae Preparata of 1.5～6 parts of Semen Persicaes of Rhizoma Corydalis
0.1～0.5 part of 1.0～4 parts of Radix Notoginseng powder of 1.0～4 portions of Radix Curcumaes of Rhizoma Chuanxiong.
The weight proportion of each raw material of optimization formula of the present invention is:
1.5～2.5 parts of 1.5～2.5 parts of living Rhizoma Cyperis of 2.5～3.5 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
0.5～1.5 part of 1.5～2.5 parts of Fructus Aurantii (parched) of 2.5～3.5 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
0.5～1.5 part of 1.5～2.5 parts of Radix Glycyrrhizae Preparata of 2.5～3.5 parts of Semen Persicaes of Rhizoma Corydalis
0.2～0.4 part of 1.5～2.5 parts of Radix Notoginseng powder of 1.5～2.5 portions of Radix Curcumaes of Rhizoma Chuanxiong.
The weight proportion of each raw material of optimum formula of the present invention is:
2 parts of 2 parts of living Rhizoma Cyperis of 3 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
1 part of 2 parts of Fructus Aurantii (parched) of 3 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
1 part of 2 parts of Radix Glycyrrhizae Preparata of 3 parts of Semen Persicaes of Rhizoma Corydalis
0.3 part of 2 parts of Radix Notoginseng powder of 2 portions of Radix Curcumaes of Rhizoma Chuanxiong.
Drug action mechanism among the present invention is as follows:
The Radix Angelicae Sinensis (processed with wine) property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Salviae Miltiorrhizae property of medicine hardship is slightly cold.GUIXIN, pericardium, Liver Channel.Have blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, the effect of removing heat from blood eliminating carbuncle.Can treat menoxenia, dysmenorrhea, amenorrhea, the stasis of blood stagnated and suffered from abdominal pain puerperal, trusted subordinate's pain, lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, heat is gone into nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore etc.(the 647th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Corydalis property of medicine suffering, hardship, temperature.GUIXIN, liver, spleen channel.Has promoting blood circulation to remove blood stasis, the effect of promoting the circulation of QI to relieve pain.Can treat obstruction of qi in the chest and cardialgia, epigastric pain, lumbago, colicky, dysmenorrhea, amenorrhea ， mass in the abdomen, the stasis of blood stagnated and suffered from abdominal pain traumatic injury etc. puerperal.(the 1261st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Flos Carthami property of medicine suffering, temperature.GUIXIN, Liver Channel.Has promoting blood circulation to restore menstrual flow, the effect of stasis-dispelling and pain-killing.Can treat the blood stasis amenorrhea, dysmenorrhea, postpartum stagnation stomachache, obstruction of qi in the chest and cardialgia ， mass in the abdomen knot is poly-, traumatic injury, arthralgia, apoplectic hemiplegia, macule etc.(the 2763rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Curcumae property of medicine suffering, hardship, cold.GUIXIN, liver, gallbladder meridian.Has promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, the effect of function of gallbladder promoting.Can treat all pains of breast abdomen side of body rib, dysmenorrhea ， mass in the abdomen, the calentura coma, demented, spit blood epistaxis, stranguria with blood, sand Stranguria, jaundice etc.(the 1855th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Living Rhizoma Cyperi property of medicine suffering, sweet, little hardship, flat.Return liver, tri-jiao channel.Has the resolving depression of regulating the flow of vital energy, regulating menstruation, antiabortive effect.Can treat distending pain over the hypochondrium, distending pain of the breast, hernia pain, menoxenia, gastral cavity abdomen feeling of fullness pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, frequent fetal movement etc.(the 2341st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii (parched) property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Glycyrrhizae Preparata property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Notoginseng powder property of medicine, temperature.Return liver, stomach, the heart, large intestine channel.Has the hemostasis dissipating blood stasis, the effect of subduing swelling and relieving pain.Can treat haematemesis, hemoptysis, hematuria is had blood in stool, dysentery, metrorrhagia, postpartum hemorrhage, traumatic hemorrhage, the tumbling down damage, obstruction of qi in the chest and cardialgia, gastral cavity are coerced the long-pending piece of Tong ， mass in the abdomen of a specified duration, the blood stasis amenorrhea, dysmenorrhea, the stasis of blood stagnated and suffered from abdominal pain sore, carbuncle and painful swelling etc. puerperal.(the 74th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis (processed with wine), Radix Salviae Miltiorrhizae and Rhizoma Corydalis; With Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Semen Persicae, Radix Curcumae and living Rhizoma Cyperi is ministerial drug; With Fructus Aurantii (parched), Radix Notoginseng powder and Radix Glycyrrhizae Preparata is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of removing obstruction in the collateral to relieve pain.The treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment diabetic cardiopathy of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic cardiopathy, and the prevention of diabetic cardiopathy is also had good effect, and the treatment diabetic cardiopathy has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic cardiopathy; Treatment diabetic cardiopathy patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 40%, and 12 examples that take a turn for the better account for 48%, and invalid 3 examples account for 12%, and total effective rate reaches 88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
2 parts of 2 parts of living Rhizoma Cyperis of 3 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
1 part of 2 parts of Fructus Aurantii (parched) of 3 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
1 part of 2 parts of Radix Glycyrrhizae Preparata of 3 parts of Semen Persicaes of Rhizoma Corydalis
0.3 part of 2 parts of Radix Notoginseng powder of 2 portions of Radix Curcumaes of Rhizoma Chuanxiong.
Preparation method is to get Radix Angelicae Sinensis (processed with wine), Radix Salviae Miltiorrhizae, Rhizoma Corydalis, Rhizoma Chuanxiong, Flos Carthami, Radix Paeoniae Rubra, Semen Persicae, Radix Curcumae, living Rhizoma Cyperi, Fructus Aurantii (parched) and Radix Glycyrrhizae Preparata to clean roguing, dry, be ground into granule, soaked 1 hour, put and decoct with water secondary in the multi-function extractor, add up the water of 10 times of amounts of medical material for the first time, decocted 1.5～2 hours, get decocting liquid, filter.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic cardiopathy that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, and one time one bag and Radix Notoginseng powder are taken after mixing it with water every day two to three times together.One month is a course of treatment.
Claims (3)
1. Chinese patent medicine for the treatment of diabetic cardiopathy is characterized in that it is made by the following weight proportion raw material:
1.0～4.0 parts of 1.0～4 parts of living Rhizoma Cyperis of 1.5～6 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
0.1～2.0 part of 1.0～4 parts of Fructus Aurantii (parched) of 1.5～6 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
0.1～2.0 part of 1.0～4 parts of Radix Glycyrrhizae Preparata of 1.5～6 parts of Semen Persicaes of Rhizoma Corydalis
0.1～0.5 part of 1.0～4 parts of Radix Notoginseng powder of 1.0～4 portions of Radix Curcumaes of Rhizoma Chuanxiong.
2. a kind of Chinese patent medicine for the treatment of diabetic cardiopathy according to claim 1, wherein the weight proportion of each raw material is:
1.5～2.5 parts of 1.5～2.5 parts of living Rhizoma Cyperis of 2.5～3.5 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
0.5～1.5 part of 1.5～2.5 parts of Fructus Aurantii (parched) of 2.5～3.5 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
0.5～1.5 part of 1.5～2.5 parts of Radix Glycyrrhizae Preparata of 2.5～3.5 parts of Semen Persicaes of Rhizoma Corydalis
0.2～0.4 part of 1.5～2.5 parts of Radix Notoginseng powder of 1.5～2.5 portions of Radix Curcumaes of Rhizoma Chuanxiong.
3. a kind of Chinese patent medicine for the treatment of diabetic cardiopathy according to claim 1, wherein the weight proportion of each raw material is:
2 parts of 2 parts of living Rhizoma Cyperis of 3 parts of Flos Carthamis of Radix Angelicae Sinensis (processed with wine)
1 part of 2 parts of Fructus Aurantii (parched) of 3 parts of Radix Paeoniae Rubra of Radix Salviae Miltiorrhizae
1 part of 2 parts of Radix Glycyrrhizae Preparata of 3 parts of Semen Persicaes of Rhizoma Corydalis
0.3 part of 2 parts of Radix Notoginseng powder of 2 portions of Radix Curcumaes of Rhizoma Chuanxiong.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101209300A CN101112595A (en) | 2007-08-29 | 2007-08-29 | Chinese patent medicine for treating diabetic cardiac disease |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101209300A CN101112595A (en) | 2007-08-29 | 2007-08-29 | Chinese patent medicine for treating diabetic cardiac disease |
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| CN101112595A true CN101112595A (en) | 2008-01-30 |
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| CNA2007101209300A Pending CN101112595A (en) | 2007-08-29 | 2007-08-29 | Chinese patent medicine for treating diabetic cardiac disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103028094A (en) * | 2013-01-16 | 2013-04-10 | 李郑生 | Chinese patent medicine for treating coronary heart disease |
-
2007
- 2007-08-29 CN CNA2007101209300A patent/CN101112595A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103028094A (en) * | 2013-01-16 | 2013-04-10 | 李郑生 | Chinese patent medicine for treating coronary heart disease |
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Open date: 20080130 |