CN101066426A - Chinese medicine for treating intermenstrual bleeding - Google Patents

Abstract

The present invention provides Chinese medicine for treating intermenstrual bleeding. The Chinese medicine is prepared with over ten kinds of Chinese medicinal materials, including motherwort, fried cattail pollen, madder, trogopterus dung, etc. It has the functions of promoting blood circulation to disperse blood clots, cooling blood and arresting bleeding. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

A kind of Chinese patent medicine for the treatment of intermenstrual bleeding

Technical field

The present invention relates to a kind of Chinese patent medicine for the treatment of intermenstrual bleeding, is that a kind of to treat intermenstrual bleeding be the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Menopathy is meant cycle, the menstrual period and unusual through the amount generation of all menstruations, and follows menstrual cycle the significant discomfort symptom to occur, or the relevant a series of symptoms that occurred before and after menopause are a class disease of feature.Menstrual cycle is normal substantially, twice month through between, in the generative forces of heaven and earth, generating period is hemorrhage, is called " intermenstrual bleeding ".Primary disease is equivalent to the western medicine ovulation bleeding, if the hemorrhage phase is long, and hypervolemia, untimely treatment further develops and can cause metrorrhagia.Midcycle claims the generative forces of heaven and earth phase again, is that the moon is smart to be enriched towards appointing, and yang-energy is gradually long, by the physiological stage of excess of YIN to excess of YANG conversion.If deficiency of kidney yin, deficiency-weakness of spleen-QI, damp and hot disturbance or blood stasis check, and make transformation between yin and yang inharmonious, and primary disease takes place then.The traditional Chinese medical science is divided into the deficiency of the kidney yin type clinically, the deficiency of spleen-QI type, and damp-heat type, disease type Coryza Treated by Syndrome Differentiation such as blood stasis type obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese patent medicine for the treatment of intermenstrual bleeding.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by the following weight proportion raw material:

1.0～4 parts in 1.0～4 portions of Radix Rubiaes of 1.5～6 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

0.1～2 part of 1.0～4 parts of rhizoma sparganic of 1.5～6 parts of Radix Rehmanniae of Herba Leonuri

0.1～2 part of 1.0～4 parts of Rhizoma Curcumae of 1.5～6 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

0.1～2 part in 1.0～4 parts of Semen Persicaes of 1.0～4 parts of Fructus Aurantiis of Cortex Moutan

The weight proportion of each raw material of optimization formula of the present invention is:

1.5～2.5 parts in 1.5～2.5 portions of Radix Rubiaes of 2.5～3.5 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

0.5～1.5 part of 1.5～2.5 parts of rhizoma sparganic of 2.5～3.5 parts of Radix Rehmanniae of Herba Leonuri

0.5～1.5 part of 1.5～2.5 parts of Rhizoma Curcumae of 2.5～3.5 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

0.5～1.5 part in 1.5～2.5 parts of Semen Persicaes of 1.5～2.5 parts of Fructus Aurantiis of Cortex Moutan

The weight proportion of each raw material of optimum formula of the present invention is:

2 parts in 2 portions of Radix Rubiaes of 3 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

1 part of 2 parts of rhizoma sparganic of 3 parts of Radix Rehmanniae of Herba Leonuri

1 part of 2 parts of Rhizoma Curcumae of 3 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

1 part in 2 parts of Semen Persicaes of 2 parts of Fructus Aurantiis of Cortex Moutan

Drug action mechanism among the present invention is as follows:

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little suffering of the Pollen Tyjphae (parched) property of medicine, flat.Return liver, the heart, spleen channel.Has hemostasis, blood stasis dispelling, diuretic effect.Can treat haematemesis, spitting of blood, epistaxis, dysentery is had blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, puerperal stasis of blood pain, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, leukorrhagia, congenital deformity of the tongue, aphtha, ear, uncontrolled urination are itched etc.(the 3423rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Oletum Trogopterori property of medicine hardship, sweet, temperature.Return liver, spleen channel.Has promoting blood circulation and stopping pain, removing stasis to stop bleeding, removing food stagnancy antidotal effect.Can treat all pains of trusted subordinate's vim and vigour, women's amenorrhea, the stasis of blood stagnated and suffered from abdominal pain metrostaxis, infantile malnutrition, snakes and scorpions centipete bite etc. puerperal.(the 517th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Rubiae property of medicine hardship, cold.Return liver, heart channel.Has cooling blood for hemostasis, the effect of blood circulation promoting and blood stasis dispelling.Can treat heat in blood spitting of blood, haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid are swollen etc.(the 2115th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Rhizoma sparganic nature and flavor suffering, hardship, flat.Return liver, spleen channel.Has removing blood stasis, circulation of qi promoting, removing food stagnancy analgesic effect.Can treat lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the food stagnation distending pain, the side of body expands down painful, amenorrhea, dysmenorrhea, puerperal abdominalgia with blood stasis, traumatic injury, skin ulcer is swollen hard, hepatosplenomegaly etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 69th page).

Rhizoma Curcumae nature and flavor hardship, suffering, temperature.Return liver, spleen channel.Have the circulation of qi promoting removing blood stasis with potent drugs, the removing food stagnancy pain relieving is changed poly-eliminating mass, the effect of antiearly pregnancy.Can treat that trusted subordinate's distending pain, lump in the abdomen, dyspepsia do not disappear, hepatosplenomegaly, abdominal pain due to blood stasis, amenorrhea due to stagnation of blood, cervical erosion, traumatic injury have a pain etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 995th page).

Semen Persicae property of medicine hardship, sweet, mild toxicity.GUIXIN, liver, large intestine channel.Has blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.Can treat dysmenorrhea, amenorrhea due to stagnation of blood, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen caking, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation etc.(the 2542nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Angelicae Sinensis, Herba Leonuri and Pollen Tyjphae (parched); With Cortex Moutan, Oletum Trogopterori, Radix Rehmanniae, Radix Paeoniae Rubra, Fructus Aurantii and Radix Rubiae is ministerial drug; With rhizoma sparganic, Rhizoma Curcumae and Semen Persicae is adjuvant.All medicines are harmonious, and are total to the tool removing damp-heat, the effect of cooling blood for hemostasis.The treatment intermenstrual bleeding has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment intermenstrual bleeding of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat intermenstrual bleeding, and the prevention of intermenstrual bleeding is also had good effect, and the treatment intermenstrual bleeding has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment intermenstrual bleeding; Treatment intermenstrual bleeding patient 13 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.6 examples of fully recovering account for 46.15%, and 5 examples that take a turn for the better account for 38.46%, and more 2 examples do not account for 15.38%, and total effective rate reaches 84.61%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction takes by weighing raw material by following weight:

2 parts in 2 portions of Radix Rubiaes of 3 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

1 part of 2 parts of rhizoma sparganic of 3 parts of Radix Rehmanniae of Herba Leonuri

1 part of 2 parts of Rhizoma Curcumae of 3 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

1 part in 2 parts of Semen Persicaes of 2 parts of Fructus Aurantiis of Cortex Moutan

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment intermenstrual bleeding that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese patent medicine for the treatment of intermenstrual bleeding is characterized in that it is made by the following weight proportion raw material:

1.0～4 parts in 1.0～4 portions of Radix Rubiaes of 1.5～6 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

0.1～2 part of 1.0～4 parts of rhizoma sparganic of 1.5～6 parts of Radix Rehmanniae of Herba Leonuri

0.1～2 part of 1.0～4 parts of Rhizoma Curcumae of 1.5～6 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

0.1～2 part in 1.0～4 parts of Semen Persicaes of 1.0～4 parts of Fructus Aurantiis of Cortex Moutan.

2, a kind of Chinese patent medicine for the treatment of intermenstrual bleeding according to claim 1, wherein the weight proportion of each raw material is:

1.5～2.5 parts in 1.5～2.5 portions of Radix Rubiaes of 2.5～3.5 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

0.5～1.5 part of 1.5～2.5 parts of rhizoma sparganic of 2.5～3.5 parts of Radix Rehmanniae of Herba Leonuri

0.5～1.5 part of 1.5～2.5 parts of Rhizoma Curcumae of 2.5～3.5 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

0.5～1.5 part in 1.5～2.5 parts of Semen Persicaes of 1.5～2.5 parts of Fructus Aurantiis of Cortex Moutan.

3, a kind of Chinese patent medicine for the treatment of intermenstrual bleeding according to claim 1, wherein the weight proportion of each raw material is:

2 parts in 2 portions of Radix Rubiaes of 3 parts of Oletum Trogopteroris of Radix Angelicae Sinensis

1 part of 2 parts of rhizoma sparganic of 3 parts of Radix Rehmanniae of Herba Leonuri

1 part of 2 parts of Rhizoma Curcumae of 3 parts of Radix Paeoniae Rubra of Pollen Tyjphae (parched)

1 part in 2 parts of Semen Persicaes of 2 parts of Fructus Aurantiis of Cortex Moutan.