CN101066337A - Chinese medicine for treating metrorrhagia and its prepn process - Google Patents

Chinese medicine for treating metrorrhagia and its prepn process Download PDF

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Publication number
CN101066337A
CN101066337A CNA2007101000579A CN200710100057A CN101066337A CN 101066337 A CN101066337 A CN 101066337A CN A2007101000579 A CNA2007101000579 A CN A2007101000579A CN 200710100057 A CN200710100057 A CN 200710100057A CN 101066337 A CN101066337 A CN 101066337A
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parts
radix
chinese medicine
metrorrhagia
blood
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101000579A priority Critical patent/CN101066337A/en
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Abstract

The present invention provides Chinese medicine for treating metrorrhagia and its preparation process. The Chinese medicine is prepared with over ten kinds of Chinese medicinal materials, including motherwort, selfheal, garden burnet charcoal, Dangshen, etc. It has the functions of promoting blood circulation to disperse blood clots, arresting bleeding and regulating menstruation. The present invention is developed through combining syndrome analyzing treatment of Chinese medicine and modern research result. The Chinese medicine has the features of determined curative effect, high safety, no toxic side effect and low cost.

Description

A kind of Chinese medicine for the treatment of metrorrhagia and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of metrorrhagia and preparation method thereof, is that a kind of to treat metrorrhagia be the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Menopathy is meant cycle, the menstrual period and unusual through the amount generation of all menstruations, and follows menstrual cycle the significant discomfort symptom to occur, or the relevant a series of symptoms that occurred before and after menopause are a class disease of feature.The women is not between menstrual period, and vagina is bled profusely suddenly, or the continuous person of dripping hematochezia, is called " metrorrhagia ".The former is called " metrorrhagia ", and the latter is called " leaking down ".If menostaxis reaches above person of 2 weeks, should belong to the metrorrhagia category, be called " metrorrhagia " or " menometrorrhagia ".General unexpected hemorrhage, the oncoming force is anxious, and crying that blood volume is many collapsed; Dripping hematochezia, the oncoming force is slow, and what blood volume was few cries Lou.Though the hemorrhage situation that collapses and leak is inequality, pathogeny is consistent, and normal conversion mutually in the advancing of disease process, and as metrorrhagia with the passing of time, QI and blood consumes hinders, and becomes leakage; Leak incessantly for a long time, patient's condition day advances, and also can become to collapse.So usually metrorrhagia also claims clinically.Say as recipes for Saving Lives: " disease of metrorrhagia, this card.Leaking down of the lighter's meaning, the very metrorrhagia of person's meaning." primary disease belongs to commonly encountered diseases, Chang Yin collapses and leaks alternately, and cause and effect is relevant, causes the touching difficulty of pathological changes more, becomes the difficult serious symptom of gynecological.Primary disease is equivalent to the irregular vagina bleeding that western medicine anovulation type dysfunctional uterine bleeding, edeitis and some neoplasmata genitalis cause.Main pathogenesis is the debility of CHONG and REN meridians, can not restrict menses.The common cause that causes the debility of CHONG and REN meridians suffers from a deficiency of the kidney, insufficiency of the spleen, heat in blood and blood stasis.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine for the treatment of metrorrhagia and preparation method thereof.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
1.5~6.0 parts of 1.5~6 parts of charred Radix Sanguisorbae of 1.5~6 parts of Herba Leonuris of Herba Agrimoniae
1.0~4.0 parts of 1.0~4 parts of Radix Rehmanniae Preparata of 1.0~4 parts of charred RADIX RUBIAEs of Pollen Tyjphae
1.0~4.0 parts of 1.0~4 parts of Spica Prunellaes of 1.0~4 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.1~0.5 part of 0.1~2 part of Radix Notoginseng powder of 0.1~2 part of Rhizoma Chuanxiong of Oletum Trogopterori
The weight proportion of each raw material of optimization formula of the present invention is:
2.5~3.5 parts of 2.5~3.5 parts of charred Radix Sanguisorbae of 2.5~3.5 parts of Herba Leonuris of Herba Agrimoniae
1.5~2.5 parts of 1.5~2.5 parts of Radix Rehmanniae Preparata of 1.5~2.5 parts of charred RADIX RUBIAEs of Pollen Tyjphae
1.5~2.5 parts of 1.5~2.5 parts of Spica Prunellaes of 1.5~2.5 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.2~0.4 part of 0.5~1.5 part of Radix Notoginseng powder of 0.5~1.5 part of Rhizoma Chuanxiong of Oletum Trogopterori
The weight proportion of each raw material of optimum formula of the present invention is:
3 parts of 3 parts of charred Radix Sanguisorbae of 3 parts of Herba Leonuris of Herba Agrimoniae
2 parts of 2 parts of Radix Rehmanniae Preparata of 2 parts of charred RADIX RUBIAEs of Pollen Tyjphae
2 parts of 2 parts of Spica Prunellaes of 2 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.3 part of 1 part of Radix Notoginseng powder of 1 part of Rhizoma Chuanxiong of Oletum Trogopterori
Drug action mechanism among the present invention is as follows:
Herba Agrimoniae property of medicine hardship, puckery, flat.Return lung, liver, spleen channel.Has astringing to arrest bleeding, removing food stagnancy dysentery relieving, the effect of removing toxic substances and promoting subsidence of swelling.Can treat spitting of blood, spit blood, epistaxis, hematuria is had blood in stool, metrorrhagia and traumatic hemorrhage, diarrhoea, dysentery is taken off the power impairment caused by overstrain, malaria, furuncle carbuncle, trichomonal vaginitis etc.(the 938th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Charred Radix Sanguisorbae property of medicine hardship, acid are slightly cold.Return liver, stomach, large intestine channel.Has cooling blood for hemostasis, the effect of heat-clearing and toxic substances removing.Can treat haematemesis, spitting of blood, epistaxis, hematuria, have blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting etc.(the 1127th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Pollen Tyjphae property of medicine, flat.Return liver, the heart, spleen channel.Has hemostasis, blood stasis dispelling, diuretic effect.Can treat haematemesis, spitting of blood, epistaxis, dysentery is had blood in stool, metrorrhagia, traumatic hemorrhage, trusted subordinate's pain, amenorrhea stomachache, puerperal stasis of blood pain, dysmenorrhea, tumbling and swelling, blood strangury and dry pain, leukorrhagia, congenital deformity of the tongue, aphtha, ear, uncontrolled urination are itched etc.(the 3423rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Charred RADIX RUBIAE property of medicine hardship, cold.Return liver, heart channel.Has cooling blood for hemostasis, the effect of blood circulation promoting and blood stasis dispelling.Can treat heat in blood spitting of blood, haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid are swollen etc.(the 2115th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature.Have nourishing YIN and supplementing blood, beneficial essence is filled out the effect of marrow.Can treat soreness of the waist and knees, osteopyrexia and fever, the night sweat seminal emission, interior-heat is quenched one's thirst, severe palpitation, menoxenia, metrostaxis, dizzy, tinnitus, early whitening of beard and hair, anemia etc.(the 197th page of chief editor such as the firm Xiao Ying of party " Chinese medicine and health food development and exploitation " People's Health Publisher).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Spica Prunellae property of medicine hardship, suffering, cold.Return liver, gallbladder meridian.Has liver heat removing and eyesight improving, the effect of powder detoxifcation.Can treat the conjunctival congestion photophobia, ophthalmalgia, it is dizzy to have a headache, tinnitus, scrofula goiter, acute mastitis mumps, carbuncle furuncle and phyma poison, acute and chronic hepatitis, hypertension etc.(the 2562nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Oletum Trogopterori property of medicine hardship, sweet, temperature.Return liver, spleen channel.Has promoting blood circulation and stopping pain, removing stasis to stop bleeding, removing food stagnancy antidotal effect.Can treat all pains of trusted subordinate's vim and vigour, women's amenorrhea, the stasis of blood stagnated and suffered from abdominal pain metrostaxis, infantile malnutrition, snakes and scorpions centipete bite etc. puerperal.(the 517th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Chuanxiong property of medicine suffering, temperature.Return liver, gallbladder, pericardium channel.Has blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores etc.(the 292nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Notoginseng powder property of medicine, temperature.Return liver, stomach, the heart, large intestine channel.Has the hemostasis dissipating blood stasis, the effect of subduing swelling and relieving pain.Can treat haematemesis, hemoptysis, hematuria is had blood in stool, dysentery, metrorrhagia, postpartum hemorrhage, traumatic hemorrhage, the tumbling down damage, obstruction of qi in the chest and cardialgia, gastral cavity are coerced the long-pending piece of Tong , mass in the abdomen of a specified duration, the blood stasis amenorrhea, dysmenorrhea, the stasis of blood stagnated and suffered from abdominal pain sore, carbuncle and painful swelling etc. puerperal.(the 74th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Herba Agrimoniae, Herba Leonuri and charred Radix Sanguisorbae; With Pollen Tyjphae, charred RADIX RUBIAE, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Codonopsis and Spica Prunellae is ministerial drug; With Oletum Trogopterori, Rhizoma Chuanxiong and Radix Notoginseng powder is adjuvant.All medicines are harmonious, and are total to the tool blood circulation promoting and blood stasis dispelling, the effect of blood-arresting catamenia-regulating.The treatment metrorrhagia has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment metrorrhagia of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat metrorrhagia, and the prevention of metrorrhagia is also had good effect, and the treatment metrorrhagia has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment metrorrhagia; Treatment metrorrhagia patient 16 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 43.75%, and 7 examples that take a turn for the better account for 43.75%, and more 2 examples do not account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
3 parts of 3 parts of charred Radix Sanguisorbae of 3 parts of Herba Leonuris of Herba Agrimoniae
2 parts of 2 parts of Radix Rehmanniae Preparata of 2 parts of charred RADIX RUBIAEs of Pollen Tyjphae
2 parts of 2 parts of Spica Prunellaes of 2 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.3 part of 1 part of Radix Notoginseng powder of 1 part of Rhizoma Chuanxiong of Oletum Trogopterori
Preparation method is to get Herba Agrimoniae, Herba Leonuri, charred Radix Sanguisorbae, Pollen Tyjphae, charred RADIX RUBIAE, Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Radix Codonopsis, Spica Prunellae, Oletum Trogopterori and Rhizoma Chuanxiong to clean roguing, dry, be ground into granule, soaked 1 hour, put and decoct with water secondary in the multi-function extractor, add up the water of 10 times of amounts of medical material for the first time, decocted 1.5~2 hours, get decocting liquid, filter.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment metrorrhagia that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, and one time one bag and Radix Notoginseng powder are taken after mixing it with water together.Every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine for the treatment of metrorrhagia and preparation method thereof is characterized in that it is made by the following weight proportion raw material:
1.5~6.0 parts of 1.5~6 parts of charred Radix Sanguisorbae of 1.5~6 parts of Herba Leonuris of Herba Agrimoniae
1.0~4.0 parts of 1.0~4 parts of Radix Rehmanniae Preparata of 1.0~4 parts of charred RADIX RUBIAEs of Pollen Tyjphae
1.0~4.0 parts of 1.0~4 parts of Spica Prunellaes of 1.0~4 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.1~0.5 part of 0.1~2 part of Radix Notoginseng powder of 0.1~2 part of Rhizoma Chuanxiong of Oletum Trogopterori.
2, a kind of Chinese medicine for the treatment of metrorrhagia according to claim 1 and preparation method thereof, wherein the weight proportion of each raw material is:
2.5~3.5 parts of 2.5~3.5 parts of charred Radix Sanguisorbae of 2.5~3.5 parts of Herba Leonuris of Herba Agrimoniae
1.5~2.5 parts of 1.5~2.5 parts of Radix Rehmanniae Preparata of 1.5~2.5 parts of charred RADIX RUBIAEs of Pollen Tyjphae
1.5~2.5 parts of 1.5~2.5 parts of Spica Prunellaes of 1.5~2.5 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.2~0.4 part of 0.5~1.5 part of Radix Notoginseng powder of 0.5~1.5 part of Rhizoma Chuanxiong of Oletum Trogopterori.
3, a kind of Chinese medicine for the treatment of metrorrhagia according to claim 1 and preparation method thereof, wherein the weight proportion of each raw material is:
3 parts of 3 parts of charred Radix Sanguisorbae of 3 parts of Herba Leonuris of Herba Agrimoniae
2 parts of 2 parts of Radix Rehmanniae Preparata of 2 parts of charred RADIX RUBIAEs of Pollen Tyjphae
2 parts of 2 parts of Spica Prunellaes of 2 parts of Radix Codonopsis of Radix Angelicae Sinensis
0.3 part of 1 part of Radix Notoginseng powder of 1 part of Rhizoma Chuanxiong of Oletum Trogopterori.
CNA2007101000579A 2007-06-05 2007-06-05 Chinese medicine for treating metrorrhagia and its prepn process Pending CN101066337A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757309B (en) * 2009-10-16 2011-12-28 西安千禾药业有限责任公司 Medicament for treating uterine bleeding and preparation process thereof
CN102485252A (en) * 2010-12-03 2012-06-06 株洲千金药业股份有限公司 Medicinal composition for treating functional metrorrhagia and preparation method thereof
CN103127409A (en) * 2013-01-23 2013-06-05 曹长兰 Drug for treating puerperium haemorrhage
CN105194390A (en) * 2015-10-08 2015-12-30 林素霞 Traditional Chinese medicine for treating metrorrhagia and metrostaxis

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757309B (en) * 2009-10-16 2011-12-28 西安千禾药业有限责任公司 Medicament for treating uterine bleeding and preparation process thereof
CN102485252A (en) * 2010-12-03 2012-06-06 株洲千金药业股份有限公司 Medicinal composition for treating functional metrorrhagia and preparation method thereof
CN102485252B (en) * 2010-12-03 2013-10-02 株洲千金药业股份有限公司 Medicinal composition for treating functional metrorrhagia and preparation method thereof
CN103127409A (en) * 2013-01-23 2013-06-05 曹长兰 Drug for treating puerperium haemorrhage
CN105194390A (en) * 2015-10-08 2015-12-30 林素霞 Traditional Chinese medicine for treating metrorrhagia and metrostaxis

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Open date: 20071107