CN101112483A - Medicine for treating rhinitis and method for preparing the same - Google Patents

Medicine for treating rhinitis and method for preparing the same Download PDF

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Publication number
CN101112483A
CN101112483A CNA2007101430882A CN200710143088A CN101112483A CN 101112483 A CN101112483 A CN 101112483A CN A2007101430882 A CNA2007101430882 A CN A2007101430882A CN 200710143088 A CN200710143088 A CN 200710143088A CN 101112483 A CN101112483 A CN 101112483A
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rhinitis
medicine
treatment
chinese medicine
medicine preparation
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CN100542575C (en
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郭锡珍
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Guo Jinliang
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Abstract

The present invention relates to a drug for treating rhinitis and the preparation method, the method includes that the Chinese eaglewood, frankincense, costustoot, croton cream, Szechuan pepper, cinnabar, realgar, Sanguis Draconis, sal ammoniac etc. are mixed and smashed, then the musk is added, the red date paste (removing the core) is used for even mixing, and then the pill is prepared. When in use, the present invention is inserted into the nasal cavity for local absorption, no pain, no trauma, and thus is applicable to people of all ages; furthermore, the present invention is safe and has no adverse reactions. The present invention has significant effects particularly for the treatment of dizziness, headache, runny nose, stuffy nose etc. caused by acute and chronic rhinitis, sinusitis and frontal sinusitis, which is a pure traditional Chinese medicine to treat the rhinitis fundamentally.

Description

A kind of medicine for the treatment of rhinitis and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine and preparation method thereof, relate to a kind of Chinese medicine preparation for the treatment of rhinitis and preparation method thereof particularly.
Background technology
The traditional Chinese medical science is said: the breathing of lung, to have one's ideas straightened out in nose, and nose is the door of breathing.Nasal disease is more, and modal is rhinitis, rhinitis be a kind ofly can cause suffering to the patient, worried frequently-occurring disease, commonly encountered diseases, the patient is numerous.Rhinitis mainly contains acute or chronic rhinitis, sinusitis, frontal sinusitis, and cardinal symptom is that giddy, headache, rhinorrhea, nasal obstruction are obstructed etc., and the rhinitis patient easily recurrence of back of catching a cold, and all makes troubles for life, work, obstinate, and consequence is with even more serious.The method of treatment rhinitis is divided two kinds of Drug therapy and operative treatments, operative therapy painful big, wound is arranged, be difficult for being accepted, so people generally adopt Drug therapy by the patient.
At present, the medicine of treatment rhinitis is a lot, for oral administration and spray-type of main branch commonly used.The major defect of oral medicine is must be after digestive tract decomposes, delivering to liver handles, certainly lead to so-called first (first-pass) effect of crossing, drug effect is damaged, deliver to nasal membrane through systemic circulation again, the dose that therefore can reach nose seldom, therefore the drug effect that can produce just still less has the shortcoming that onset is slow, drug effect is little.Yet the main component in the spray commonly used now contains Herba Ephedrae, Herba Asari, the storehouse ears or side handles of a utensil, the Radix Angelicae Dahuricae, Rhizoma Acori Graminei, Fructus Gleditsia etc. mostly, and the said medicine shortcoming that all toxic side effect is big or toxicity is big, life-time service can damage people's respiratory center nervous system.
Therefore, need to seek a kind of therapeutic effect ideal, pharmaceutical preparation that toxic and side effects is little.
Summary of the invention
The objective of the invention is problem at above-mentioned existence provide a kind of easy to use, effect significantly, can comparatively fast remove or alleviate the medicine of patient suffering's treatment rhinitis, and the method that this medicine of preparation is provided.
According to a first aspect of the present invention, a kind of medicine for the treatment of rhinitis is provided, this medicine is formed (component by weight) by following raw material components:
Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-3Og, Sal Ammoniacus 10-15g, Moschus 5-10g.
Preferably, the medicine of treatment rhinitis is made up of above-mentioned ten flavor medicated powder ends and ripe Fructus Jujubae, recommends to use the ripe Fructus Jujubae of enucleation, and wherein Moschus can be the artificial Moschus.
According to a second aspect of the present invention, a kind of Chinese medicine preparation for the treatment of rhinitis is provided, it comprises the medicine of the above-mentioned treatment rhinitis for the treatment of effective dose and pharmaceutically acceptable carrier.
Preferably, described Chinese medicine preparation comprises any one pharmaceutically acceptable dosage form.
Preferably, described Chinese medicine preparation is tablet, capsule, granule, pill, powder, quick-dissolving agent or drop.
More preferably, described Chinese medicine preparation is a spray.
According to a third aspect of the present invention, a kind of method for preparing the medicine for the treatment of rhinitis is provided, described method comprises the following steps:
(1) with Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g, crushing screening;
(2) with the component uniform mixing after the above-mentioned pulverizing;
(3) add Moschus moschiferous perfume (or spice);
(4), add that acceptable accessories or complementary composition make medically operable medicament according to conventional method medically.
According to a fourth aspect of the present invention, a kind of method for preparing the medicine for the treatment of rhinitis is provided, described method comprises the following steps:
((1) is with Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g, crushing screening;
(2) with the component uniform mixing after the above-mentioned pulverizing;
(3) add Moschus moschiferous perfume (or spice);
(4), re-use ripe Fructus Jujubae and uniformly mix with behind the said medicine uniform mixing;
(5), add that acceptable accessories or complementary composition make medically operable medicament according to conventional method medically.
The raw material of medicine of the present invention all derives from natural Chinese medicine, and is evident in efficacy, and has no side effect.Its treating both the principal and secondary aspects of a disease, method of treatment are more reasonable, can be releasing rhinitis slight illness and have given play to definite curative effect.
The specific embodiment
The present invention for the inventor through learning for many years and study intensively, and put into practice for many years and test, the medicine of effective treatment rhinitis of developing.
Embodiment one:
Take by weighing Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g by weight, clean, concoct, remove impurity respectively, dry then, pulverize the back and cross 300 mesh sieves, preferred 100 mesh sieves that use recommend to adopt 50 mesh sieves; Add Moschus 5-10g then, and mix homogeneously.Wherein Moschus can be the artificial Moschus.Adopt method well known in the art, make medically acceptable dosage form.
Embodiment two:
Take by weighing Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g by weight, clean, concoct, remove impurity respectively, dry then, pulverize the back and cross 300 mesh sieves, preferred 100 mesh sieves that use recommend to adopt 50 mesh sieves; Add Moschus 5-10g then, and mix homogeneously; After this use ripe Fructus Jujubae to mix, recommend to use the ripe Fructus Jujubae of enucleation, wherein Moschus can be the artificial Moschus.Adopt method well known in the art, make medically acceptable dosage form.
Embodiment three.Adopt method well known in the art, make Chinese medicine preparation, it comprises the medicine of the above-mentioned treatment rhinitis for the treatment of effective dose and pharmaceutically acceptable carrier, and described Chinese medicine preparation comprises any one pharmaceutically acceptable dosage form; Preferably, be tablet, capsule, granule, pill, powder, quick-dissolving agent or drop.More preferably, described Chinese medicine preparation is a spray.
What further specify is, in technique scheme, can add effective ingredient and to add acceptable accessories or complementary composition.
Fill in the pill of nasal cavity when the said medicine component often is made into to use or inject directly to spray, powder or drop in the nasal cavity, through patient's local absorption, no pain, no wound is applicable to each age groups, safety has no adverse reaction.Being used in particular for treating that acute or chronic rhinitis, sinusitis, the caused giddy of frontal sinusitis, headache, rhinorrhea, nasal obstruction be obstructed etc. that effect is remarkable, is a kind of pure Chinese medicine medicine of fundamentally treating rhinitis.
What need state in addition is, this drug component does not experimentize to the anemia of pregnant woman, and whether still can not determine has other harmful effects to anemia of pregnant woman and fetus, so anemia of pregnant woman's forbidding.
For showing the significant curative effect of Drug therapy rhinitis of the present invention, the diagnostic criteria of the present invention from reach " the disease of tcm diagnosis criterion of therapeutical effect " diagnosis of formulating according to State Administration of Traditional Chinese Medicine the special outpatient clinic in hospital is diagnosed as among the rhinitis patient selects case, through the clinical observation of 326 routine systems, and to select medical history, the state of an illness, age, sex and suitable rhinitis 175 examples of former Therapeutic Method be matched group, carries out medication and long-term follow and follow up a case by regular visits to.
Show in the following table that in two groups of experiments, the cure rate of treatment group and effective percentage be apparently higher than matched group, thereby verified the significant curative effect of this Drug therapy rhinitis.
The example number Cure (%) Effectively (%) Invalid (%) Total effective rate (%)
The treatment group 326 242(74.23) 72(22.09) 12(2.87) 97.13
Matched group 175 46(26.29) 59(33.71) 70(40.00) 60.00
Be the several typical medication example of following up a case by regular visits to below:
Example 1: Huang, the man, 10 years old, frontal sinusitis, was thoroughly cured at course of treatment of medication;
Example 2: Zheng, woman, 18 years old, sinusitis, course of treatment of medication, recovery from illness;
Example 3: Lee so-and-so, man, 54 years old, rhinitis, medical history more than 20 year, two courses of treatment of medication, recovery from illness;
Example 4: the king so-and-so, woman, 20 years old, rhinitis, medical history 3 years, course of treatment of medication, recovery from illness;
Example 5: Fan so-and-so, the man, 11 years old, rhinitis, medical history 1 year, is cured at course of treatment of medication;
Example 6: the river, the woman, 9 years old, rhinitis, was cured at course of treatment of medication;
Example 7: Ma, the man, 40 years old, sinusitis, medical history 11 years, is cured at course of treatment of medication;
Example 8: Zhang, the man, 56 years old, rhinitis, medical history be more than 4 years, two courses of treatment of medication, cures.
Medicine of the present invention shows that through the result of clinical use the medicine of above-mentioned treatment rhinitis has following advantage:
1, medicine of the present invention is fundamentally dispelled rhinitis;
2, curative effect of medication of the present invention is high, can accelerate the rhinitis symptom and alleviate, and has greatly shortened treatment cycle;
3, because this drug component is made arbitrarily medically acceptable formulation, so the patient is simple, convenient when using this kind medicine, can not make troubles to life, and can be repeatedly used;
4, the present invention is take natural Chinese medicinal herb as raw material, and is nontoxic, and nasal cavity is had no side effect.
As above-mentioned, the clear medicine of having described in detail the treatment rhinitis that the present invention proposes, medicament and preparation method thereof. But, although be shown specifically and described the present invention with reference to the preferred embodiments of the present invention, but this area those skilled in the art are appreciated that in the situation of the spirit and scope of the present invention that do not deviate from the claims definition, can make various modifications in form and details.

Claims (10)

1. medicine for the treatment of rhinitis is characterized in that what this medicine was made by the following weight proportion raw material:
Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g, Moschus 5-10g.
2. medicine according to claim 1 is characterized in that also comprising ripe Fructus Jujubae.
3. medicine according to claim 2 is characterized in that ripe Fructus Jujubae is the ripe Fructus Jujubae of enucleation.
4. medicine according to claim 1 is characterized in that Moschus is the artificial Moschus.
5. a Chinese medicine preparation for the treatment of rhinitis is characterized in that comprising the medicine of arbitrary described treatment rhinitis in the claim 1 to 4 for the treatment of effective dose and pharmaceutically acceptable carrier.
6. Chinese medicine preparation according to claim 5 is characterized in that described Chinese medicine preparation comprises any one pharmaceutically acceptable dosage form.
7. Chinese medicine preparation according to claim 6 is characterized in that described Chinese medicine preparation is tablet, capsule, granule, pill, powder, quick-dissolving agent or drop.
8. Chinese medicine preparation according to claim 6 is characterized in that described Chinese medicine preparation is a spray.
9. a method for preparing the medicine for the treatment of rhinitis is characterized in that described method comprises the following steps:
(1) general's Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g crushing screening by weight;
(2) with the component uniform mixing after the above-mentioned pulverizing;
(3) add Moschus moschiferous perfume (or spice);
(4), add that acceptable accessories or complementary composition make medically operable medicament according to conventional method medically.
10. a method for preparing the medicine for the treatment of rhinitis is characterized in that described method comprises the following steps:
(1) general's Lignum Aquilariae Resinatum 20-30g, Olibanum 15-25g, Radix Aucklandiae 5-10g, Semen Crotonis Pulveratum 10g, Fructus Zanthoxyli 5g, Cinnabaris 5-10g, Realgar 5-10g, Sanguis Draxonis 20-30g, Sal Ammoniacus 10-15g crushing screening by weight;
(2) with the component uniform mixing after the above-mentioned pulverizing;
(3) add Moschus moschiferous perfume (or spice);
(4), re-use ripe Fructus Jujubae and uniformly mix with behind the said medicine uniform mixing;
(5), add that acceptable accessories or complementary composition make medically operable medicament according to conventional method medically.
CNB2007101430882A 2007-08-23 2007-08-23 A kind of medicine for the treatment of rhinitis and preparation method thereof Expired - Fee Related CN100542575C (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102872169A (en) * 2012-10-19 2013-01-16 黄庆德 Medicine composition for treating chronic rhinitis and preparation method of medicine composition
CN103893297A (en) * 2014-04-21 2014-07-02 张金淼 Traditional Chinese medicine ointment for treating nasosinusitis
CN104382886A (en) * 2014-10-24 2015-03-04 吴久标 Nasal smoked medicine stick
CN106334034A (en) * 2016-10-13 2017-01-18 中国热带农业科学院热带生物技术研究所 Traditional Chinese medicine compositon, nose drop containing same and application thereof
CN113713011A (en) * 2021-09-17 2021-11-30 蒋占交 Traditional Chinese medicine composition for treating rhinitis and preparation method thereof

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107137547A (en) * 2017-04-13 2017-09-08 宋玉良 Preparation and application method of a kind of rhinitis with nasal obstruction ball

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102872169A (en) * 2012-10-19 2013-01-16 黄庆德 Medicine composition for treating chronic rhinitis and preparation method of medicine composition
CN102872169B (en) * 2012-10-19 2014-01-22 黄庆德 Medicine composition for treating chronic rhinitis and preparation method of medicine composition
CN103893297A (en) * 2014-04-21 2014-07-02 张金淼 Traditional Chinese medicine ointment for treating nasosinusitis
CN103893297B (en) * 2014-04-21 2015-12-02 张金淼 A kind of Chinese medicinal ointment for the treatment of sinusitis
CN104382886A (en) * 2014-10-24 2015-03-04 吴久标 Nasal smoked medicine stick
CN106334034A (en) * 2016-10-13 2017-01-18 中国热带农业科学院热带生物技术研究所 Traditional Chinese medicine compositon, nose drop containing same and application thereof
CN113713011A (en) * 2021-09-17 2021-11-30 蒋占交 Traditional Chinese medicine composition for treating rhinitis and preparation method thereof

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Effective date of registration: 20180927

Address after: 055250 No. 2 team, former village 2, diecun Township, Julu County, Xingtai, Hebei

Patentee after: Guo Jinliang

Address before: 055250 No. 036, former village, diecun Township, Julu County, Hebei

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