CN104288727A - Special healthy traditional Chinese medicine compound preparation for infantile common cold due to wind-cold - Google Patents
Special healthy traditional Chinese medicine compound preparation for infantile common cold due to wind-cold Download PDFInfo
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- CN104288727A CN104288727A CN201410536778.4A CN201410536778A CN104288727A CN 104288727 A CN104288727 A CN 104288727A CN 201410536778 A CN201410536778 A CN 201410536778A CN 104288727 A CN104288727 A CN 104288727A
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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Abstract
The invention discloses a special healthy traditional Chinese medicine compound preparation for infantile common cold due to wind-cold. The preparation is prepared from the following components in parts by weight: 10 parts of purple perilla, 10 parts of herba schizonepetae, 10 parts of folium isatidis, 10 parts of saposhnicovia divaricata, 10 parts of radix bupleuri, 10 parts of peppermint and 10 parts of ginger. The preparation has the advantages of simple and easily available raw materials, simple preparation, no toxic effect and low cost, is put into a water bath when used, is capable of effectively relieving headache, nasal obstruction, running nose and other uncomfortable feeling caused by common cold due to wind-cold to avoid pains of needle and drug taking, beneficial ingredients absorbed by body surface can be maximized, the response is quicker than that of a common medicine, irritation of the medicine on oral mucosa and digestive tracts can be reduced, and the toxic and harmful effect on liver, kidneys and other organs after the medicine directly enters systemic circulation can be reduced.
Description
Technical field
The present invention relates to a kind of Chinese traditional compound medicine, especially a kind of Chinese traditional compound medicine being used for the treatment of anemofrigid cold.
Background technology
Flu is a kind of multiple respiratory tract disease, and infectiousness is high, and cold clinical performance is a lot, as treated not in time, easily causes serious complication.In the traditional Chinese medical science, the flu that wind and cold climate change causes is referred to as diseases caused by exogenous pathogenic factor, flu body asthenic fire Sheng arrived is referred to as interior sense.In life, medicine and the method for the treatment of flu are varied, and common oral medicine is larger to human injury, particularly to the oral mucosa of human body and digestive tract stimulation maximum, some medicine even toxic side effect, the course for the treatment of is long, can not effect a radical cure, although therapy treatment cycle is short and common drop is had an injection, instant effect, but easily cause the symptoms such as irritated, expensive, inconvenient.
The Chinese patent that application number is 201110140620.1 discloses a kind of compositions of anti-influenza of killing the virus and the anti-flu made by said composition is pasted, compositions comprises the effective ingredient that 1-30 weight portion is selected from aromatics Chinese medicine volatile extract and aromatic essential oil, 10-20 weight portion and the compatible polymer colloid with space network of this effective ingredient, the excipient of 0.5-1 weight portion.The weak point of this technical scheme is: 1. there is certain skin irritation side effect: because the air-tightness of patch is strong, so be applied to skin for a long time, make the poor easy anaerobic respiration of skin breathability, even produces skin and the irritative response such as to itch, 2. the skin of easy damaged infant: because patch has extremely strong adhesion to skin, and the skin of infant is very tender, so the epidermal tissue that can dampen child time tearing flu is pasted, makes skin damage, 3. there is the safety risks of Clinical practice: well-known, different pharmaceutical is due to the difference of component or content, incompatibility can be there is, but the aromatics Chinese medicine of this technical scheme contain induce sweat, removing dampness, invigorate blood circulation, the component of the different drug action such as warming the interior, and component is arbitrary proportion combination, objectively there is the probability of pharmaceutical incompatibility, virtually add the security risks of Clinical practice, 4. there is the effectiveness risk for the treatment of anemofrigid cold disease: well-known, the pathogenesis of various disease is all different from pathological characteristic, therefore the medicine with specific drug effect is needed to carry out immunotherapy targeted autoantibody, but the aromatics Chinese medicine of this technical scheme is contained and is induced sweat, removing dampness, invigorate blood circulation, the component of the different drug action such as warming the interior, and as its say that there is sterilization, enhancing immunity, flu-prevention, hand-foot-mouth disease, chickenpox, the effect of the many diseases of the treatment such as measles, the medicine that side demonstrates this technical scheme cannot treat anemofrigid cold disease targetedly, and find through inventor's experimental verification, this technical scheme treatment effect of anemofrigid cold non-significant.
Application number be 200910041596.9 Chinese patent disclose a kind of external washout with traditional Chinese herbs formula of liquid of fever caused by exogenous pathogens, this invention comprises three kinds of formula materials and consumption composition, treat the Chinese medicine formula raw material of wherein treating the cold, fever caused by affection of exogenous wind-cold respectively and consumption consists of Herba Schizonepetae 5 grams-50 grams, Folium Perillae 5 grams-50 grams, Radix Bupleuri 5 grams-50 grams, Folium Artemisiae Argyi 30 grams-100 grams, Radix Saposhnikoviae 5 grams-50 grams, Rhizoma Et Radix Notopterygii 5 grams-50 grams, Ramulus Cinnamomi 5 grams-50 grams, the Radix Angelicae Dahuricae 5 grams-50 grams, Rhizoma Zingberis Recens 30 grams-100 grams, by by medicinal liquid shower drip washing fried for this formula, stifling bath, scouring or warm water dipping bath reach the cold, fever for the treatment of and being caused by affection of exogenous wind-cold.The weak point of this technical scheme is: 1. formula material is more, and cost of manufacture is expensive, and allotment is complicated; 2. wherein the consumption of Folium Artemisiae Argyi is 30 grams-100 grams, the consumption that accounting is more in formula, has certain inhibitory action after excessive Folium Artemisiae Argyi life-time service to human nerve.
In sum, how to provide a kind of have non-stimulated, safety and comfort effectively, allocate simple, with strong points, raw material and be simple and easy to get and the compound Chinese medicinal preparation being exclusively used in treatment anemofrigid cold had no side effect, be the art personnel continue to solve technical barrier.
Summary of the invention
For the deficiency that prior art exists, the object of the invention is to provide a kind of chill cold in children to keep healthy special compound Chinese medicinal preparation, is put in water-bath, can alleviates the discomfort such as headache, nasal obstruction, watery nasal discharge caused by anemofrigid cold.
A kind of chill cold in children of the present invention keeps healthy special compound Chinese medicinal preparation, the technical scheme taked is: medicine is made up of the raw material of following weight proportioning, Folium Perillae 5-15 part, Herba Schizonepetae 5-15 part, Folium Isatidis 5-15 part, Radix Saposhnikoviae 5-15 part, Radix Bupleuri 5-15 part, Herba Menthae 5-15 part, Rhizoma Zingiberis Recens 5-15 part.
A kind of chill cold in children keeps healthy special compound Chinese medicinal preparation, the optimal technical scheme taked is: medicine is made up of the raw material of following weight proportioning, Folium Perillae 10 parts, Herba Schizonepetae 10 parts, Folium Isatidis 10 parts, Radix Saposhnikoviae 10 parts, Radix Bupleuri 10 parts, Herba Menthae 10 parts, 10 parts, Rhizoma Zingiberis Recens.
A kind of chill cold in children keeps healthy special compound Chinese medicinal preparation, be prepared from primarily of following step: get Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Folium Isatidis and Radix Bupleuri mixing, soak about 30 minutes, separately get Rhizoma Zingiberis Recens and smash to pieces, be placed in the soak of Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Folium Isatidis and Radix Bupleuri, boil rapidly with higher than 300 degrees Celsius of intense fires, after use 150-170 degree Celsius of slow fire instead and maintain, approximately pass through 20 minutes and add Herba Menthae continuation slow fire boiling 10 minutes, decoct and get liquid.
Using method: during use, the proportioning of medicament and water is 1:80, stir with hands and get final product balneation, after baby adapts to, water temperature is added to 43-45 degree Celsius, each bathing 10-15 minute, dab whole body skin, slightly perspire with baby and be advisable, need not rinse with clear water after bath, keep suitable indoor temperature during bathing, after bath, suitably drink boiled water.
The advantage of medicine of the present invention is: the present invention with Folium Perillae, Herba Schizonepetae, Folium Isatidis, Radix Saposhnikoviae for principal agent, Radix Bupleuri, Herba Menthae, Rhizoma Zingiberis Recens are that accessory drugs combinationally uses, the synergism between each medicine can be given full play to, have non-stimulated, safety and comfort effectively, simple, the raw material of allotment is simple and easy to get and has no side effect, the advantage such as with strong points, effectively can help the discomfort such as headache, nasal obstruction, watery nasal discharge alleviated because anemofrigid cold causes.Be put in during use in water-bath, the beneficiating ingredient of External absorbability can reach maximization, therefore it is faster than common drug treatment to take effect, avoid having an injection by pain, take medicine and suffer hardships, decrease medicine and toxic action to liver, kidney and other organs after systemic circulation is directly entered to oral mucosa and gastral stimulation and medicine.
Each raw material pharmacological effect is respectively:
Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae: relieving the exterior syndrome by diaphoresis, for wind and cold table disease, see aversion to cold, heating, the disease such as lossless, and the normal Rhizoma Zingiberis Recens that coordinates is with using;
Folium Isatidis: heat-clearing and toxic substances removing;
Radix Bupleuri: induce sweat and bring down a fever;
Herba Menthae: pharynx-clearing throat-benefiting;
Rhizoma Zingiberis Recens: cold expelling diaphoresis, preventing phlegm from forming and stopping coughing.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not restriction of the present invention, those skilled in the art are according to basic ideas of the present invention, various amendment or improvement can be made, but only otherwise come off basic thought of the present invention, all within the scope of the present invention.
A kind of chill cold in children of embodiment 1 the present invention keeps healthy the preparation of special compound Chinese medicinal preparation
Get each 10 grams of mixing of Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Folium Isatidis and Radix Bupleuri, soak about 30 minutes, separately get 10 grams, Rhizoma Zingiberis Recens and smash to pieces, be placed in the soak of Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Folium Isatidis and Radix Bupleuri, boil rapidly with high heat, after use slow fire instead and maintain, approximately pass through 20 minutes and add Herba Menthae 10 grams, continue with slow fire boiling 10 minutes.
Experimental example
Choose the anemofrigid cold infant for the treatment of in my Out-patient Department portion or carry out in 50 example year May in June, 2011 to 2012 in hospital, wherein man 25 example, female 25 example, the infant mean age was 2 one full year of life, had the symptom such as fever with aversion to cold, lossless, head-body-pain, nasal obstruction, snivel, cough, sneeze.According to patient admits's time, above infant is divided into treatment group and matched group at random, often organizes each 25 routine infants.Man 13 example in treatment group, female 12 example; Man 12 example in matched group, female 13 example.Contrast the basic document such as sex, age, symptom of two groups of infants, no significant difference, p>0.05, has comparability.
Therapeutic Method
Add in 20L to the treatment group infant chill cold in children of the 250ml embodiment of the present invention 1 kept healthy special compound Chinese medicinal preparation, to stir balneation with hands, after infant adapts to, water temperature is added to 43-45 degree Celsius, bathing 10-15 minute, dab whole body skin, slightly perspire with infant and be advisable, need not rinse with clear water after bath, keep suitable indoor temperature during bathing, after bath, suitably drink boiled water.Every day 3 times, 1 time 1 dose.Continuous use 4 days, treatment group infant stops using other water-bath health product at experimental session.
Matched group infant uses GANMAO QINGRE KELI to treat, every day 3 times, one time 1 bag, continuously use 4 days, observe situation of change and the untoward reaction of body temperature, sign before and after treatment.
Curative effect determinate standard
Compare the therapeutic effect of two groups of infants, wherein cure as infant medication is after 4 days, symptom and sign disappears; Effective for medication after 4 days symptom obviously alleviate, most of sign disappears; Effectively for medication after 4 days symptom alleviate, part sign disappears; Invalidly symptom and sign can not be made after 4 days to disappear for medication.Total effective rate is: [(curing number of cases+effective number of cases)/total number of cases] %.Two groups of infant skin lesion resume speeds are compared.
Statistical method
This experimental data adopts SPSS13.0 software to carry out statistical analysis, and wherein measurement data contrast adopts t inspection, and enumeration data contrast adopts X 2 test, with p < 0.05 for difference has statistical significance.
Therapeutic outcome
| ? | Patient numbers; M-F | Cure number | Effective number | Significant figure | Invalid number | Total effective rate |
| Treatment group | 25(man 13; Female 12) | 20 | 2 | 2 | 1 | 88% |
| Matched group | 25(man 12; Female 13) | 12 | 8 | 3 | 2 | 80% |
The routine infant for the treatment of group 25 cures 20 examples, and proportion is 80.0%, effective 2 examples, and proportion is 8.0%, and total effective rate is 88.0%; The routine infant of matched group 25 cures 12 examples, and proportion is 48.0%, and effective 8 examples, proportion is 32.0%, and total effective rate is 80.0%.Comparing result between two groups of infant therapeutic effect shows, the contrast therapy group between two groups of infant therapeutic effect is better than matched group, containing there being statistical significance (p<0.05).According to statistical result, can show that the compound Chinese medicinal preparation that infant uses a kind of chill cold in children of the present invention to keep healthy special treats the better conclusion of anemofrigid cold curative effect.
Claims (4)
1. chill cold in children keeps healthy a special compound Chinese medicinal preparation, it is characterized in that it is made up of the raw material of following weight proportioning: Folium Perillae 5-15 part, Herba Schizonepetae 5-15 part, Folium Isatidis 5-15 part, Radix Saposhnikoviae 5-15 part, Radix Bupleuri 5-15 part, Herba Menthae 5-15 part, Rhizoma Zingiberis Recens 5-15 part.
2. a kind of chill cold in children according to claim 1 keeps healthy special compound Chinese medicinal preparation, it is characterized in that it is made up of the raw material of following weight proportioning: Folium Perillae 10 parts, Herba Schizonepetae 10 parts, Folium Isatidis 10 parts, Radix Saposhnikoviae 10 parts, Radix Bupleuri 10 parts, Herba Menthae 10 parts, 10 parts, Rhizoma Zingiberis Recens.
3. a kind of chill cold in children according to claim 1 keeps healthy special compound Chinese medicinal preparation, be prepared from primarily of following step: get Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Folium Isatidis and Radix Bupleuri mixing, soak about 30 minutes, separately get Rhizoma Zingiberis Recens and smash to pieces, be placed in the soak of Folium Perillae, Herba Schizonepetae, Radix Saposhnikoviae, Folium Isatidis and Radix Bupleuri, boil rapidly with the intense fire higher than 300 degrees Celsius, after use instead 150-170 degree Celsius slow fire maintain, approximately pass through 20 minutes and add Herba Menthae continuation slow fire boiling 10 minutes, decoct and get liquid.
4. a kind of chill cold in children according to claim 1 keeps healthy special compound Chinese medicinal preparation, its purposes is: the special compound Chinese medicinal preparation that described chill cold in children kept healthy is put in water-bath, effectively can alleviate the discomforts such as the headache because anemofrigid cold causes, nasal obstruction, watery nasal discharge.
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| CN104587334A (en) * | 2015-02-04 | 2015-05-06 | 吴自和 | Traditional Chinese medicine powder for treating wind-cold influenza |
| CN105412383A (en) * | 2015-12-22 | 2016-03-23 | 路军贞 | Medicated bath bag for infantile wind-cold type common cold |
| CN105853800A (en) * | 2016-05-24 | 2016-08-17 | 王桂英 | Traditional Chinese medicine for treating common cold due to wind-cold |
| CN108704079A (en) * | 2018-08-20 | 2018-10-26 | 李时珍（广州）健康科技有限公司 | A kind of Traditional medicine bubble bath composition, preparation method and application improving cold in children fever symptoms |
| CN115317440A (en) * | 2022-08-25 | 2022-11-11 | 包敏 | Anti-cold bathing medicament and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587334A (en) * | 2015-02-04 | 2015-05-06 | 吴自和 | Traditional Chinese medicine powder for treating wind-cold influenza |
| CN104587334B (en) * | 2015-02-04 | 2017-09-15 | 吴自和 | A kind of traditional Chinese powder medicine for being used to treat anemofrigid cold |
| CN105412383A (en) * | 2015-12-22 | 2016-03-23 | 路军贞 | Medicated bath bag for infantile wind-cold type common cold |
| CN105853800A (en) * | 2016-05-24 | 2016-08-17 | 王桂英 | Traditional Chinese medicine for treating common cold due to wind-cold |
| CN108704079A (en) * | 2018-08-20 | 2018-10-26 | 李时珍（广州）健康科技有限公司 | A kind of Traditional medicine bubble bath composition, preparation method and application improving cold in children fever symptoms |
| CN115317440A (en) * | 2022-08-25 | 2022-11-11 | 包敏 | Anti-cold bathing medicament and preparation method thereof |
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| CN104288727B (en) | 2018-07-20 |
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