CN104288727B - A kind of dedicated compound Chinese medicinal preparation of chill cold in children health care - Google Patents
A kind of dedicated compound Chinese medicinal preparation of chill cold in children health care Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a kind of dedicated compound Chinese medicinal preparation of chill cold in children health care, drug forms by weight:10 parts of purple perilla, 10 parts of schizonepeta, 10 parts of folium isatidis, windproof 10 parts, 10 parts of radix bupleuri, 10 parts of peppermint, 10 parts of ginger, raw material of the present invention are simple and easy to get, proportioning is simple, it is without side-effects, it is at low cost, it is put in water-bath when use, it can be effectively relieved and have a headache caused by anemofrigid cold, nasal obstruction, the discomforts such as runny nose, it avoids having an injection by pain, it takes medicine and suffers hardships, the beneficiating ingredient of External absorbability can reach maximization, it takes effect than common drug treatment faster, and drug can be reduced, mucous membrane of mouth and gastral stimulation and drug are directly entered after systemic circulation to liver, the toxic action of kidney and other organs.
Description
Technical field
The present invention relates to a kind of Chinese traditional compound medicine, especially a kind of Chinese traditional compound medicines for treating anemofrigid cold.
Background technology
Flu is a kind of multiple breathing problem, and infectiousness is high, and there are many cold clinical performance, are such as not treated in time, and hold
Easily cause serious complication.In Chinese medicine, flu caused by chill climate change is referred to as diseases caused by external factors, physically weak fire is arrived
Flu is referred to as to really feel.In life, drug and the method for treating flu are varied, and common medicine for oral administration compares human injury
Greatly, maximum especially is stimulated to the mucous membrane of mouth of human body and alimentary canal, some drugs even toxic side effect, the course for the treatment of is long, cannot
Radical cure, although and common drop therapy treatment cycle of having an injection is short, it is quick, easily cause the symptoms such as allergy, price is high
It is expensive, it has not been convenient to.
Application No. is 201110140620.1 Chinese patents to disclose a kind of composition and the group of anti-influenza of killing the virus
The anti-flu patch made by object is closed, composition includes that 1-30 parts by weight are selected from aromatics Chinese medicine volatile extract and fragrant plant
The active ingredient of essential oil, 10-20 parts by weight and the compatible polymer colloid with space network of the active ingredient, 0.5-
The excipient of 1 parts by weight.The deficiency of this technical solution lies in that:1. there are certain skin irritation side effects:Due to patch
The air-tightness of agent is strong, so being applied to skin for a long time so that the poor easy anaerobic respiration of skin breathability, or even generate skin itch etc.
Irritative response;2. the skin of easy damaged infant:Since patch has skin extremely strong adhesion strength, and the skin of infant is non-
It is often tender, the epidermal tissue of child can be dampened when so tearing flu patch so that skin damage;3. there are Clinical practices
Safety risks:It is well known that different pharmaceutical due to component or the difference of content, can have an incompatibility, however the technical side
The aromatics Chinese medicine of case such as covers in inducing diaphoresis, dampness elimination, promoting blood circulation, temperature at the component of different drug actions, and group is divided into arbitrary proportion group
Close, objectively for there is a possibility that pharmaceutical incompatibility, virtually increase the security risks of Clinical practice;4. existing
Treat the validity risk of anemofrigid cold disease:It is well known that the pathogenesis of various disease is all different from pathological characteristic, therefore
Need to have the drug of specific drug effect to carry out immunotherapy targeted autoantibody, however the aromatics Chinese medicine of the technical solution cover inducing diaphoresis, dampness elimination,
The component of different drug actions such as in promoting blood circulation, temperature, and as it is sayed with sterilization, strengthen immunity, flu-prevention, brothers mouthful
Disease, varicella, measles etc. treat the effect of many diseases, and the drug that side demonstrates the technical solution can not targetedly treat wind
Cold cold disease, and found through inventor's experimental verification, the effect of technical solution treatment anemofrigid cold is simultaneously non-significant.
Application No. is 200910041596.9 Chinese patents to disclose a kind of external washout with traditional Chinese herbs formula of liquid of fever caused by exogenous pathogens, should
Invention includes three kinds of formula materials and dosage composition, treats the Chinese medicine for wherein treating the cold, fever caused by catching cold respectively
Formula material and dosage group become 5 grams -50 grams of schizonepeta, 5 grams -50 grams of perilla leaf, 5 grams -50 grams of radix bupleuri, 30 grams -100 grams of folium artemisiae argyi,
Windproof 5 grams -50 grams, 5 grams -50 grams of Rhizoma Et Radix Notopterygii, 5 grams -50 grams of cassia twig, 5 grams -50 grams of the root of Dahurain angelica, 30 grams -100 grams of personated old man ginger, by should
Be formulated it is fried made of liquid take a shower elution, fumigate bath, clean or warm water dipping bath reach treatment by caused sense of catching cold
Emit fever.The deficiency of this technical solution lies in that:1. formula material is more, cost of manufacture is expensive, and allotment is complicated;2. wherein ending
The dosage of grass is 30 grams -100 grams, more dosage is accounted in formula, to human nerve meeting after excessive wormwood long-time service
There is certain inhibiting effect.
In conclusion how to provide a kind of with non-stimulated, safety and comfort are effective, allotment is simple, with strong points, raw material is simple
Dan Yi takes and the compound Chinese medicinal preparation for being exclusively used in treatment anemofrigid cold without side-effects, is that those skilled in the art continues to solve
Technical barrier.
Invention content
In view of the deficienciess of the prior art, present invention aims at provide a kind of chill cold in children health care it is dedicated in
Medicine compound preparation, is put in water-bath, and the discomforts such as headache, nasal obstruction, runny nose caused by anemofrigid cold can be alleviated.
A kind of dedicated compound Chinese medicinal preparation of chill cold in children health care of the present invention, the technical solution taken are:Drug by
The raw material composition of following weight proportioning, 5-15 parts of purple perilla, 5-15 parts of schizonepeta, 5-15 parts of folium isatidis, 5-15 parts windproof, radix bupleuri 5-15
Part, 5-15 parts of peppermint, 5-15 parts of ginger.
A kind of dedicated compound Chinese medicinal preparation of chill cold in children health care, the optimal technical scheme taken are:Drug is under
State weight proportion raw material composition, 10 parts of purple perilla, 10 parts of schizonepeta, 10 parts of folium isatidis, 10 parts windproof, 10 parts of radix bupleuri, 10 parts of peppermint,
10 parts of ginger.
A kind of dedicated compound Chinese medicinal preparation of chill cold in children health care, is mainly prepared by following step:Take purple perilla,
Schizonepeta, windproof, folium isatidis and radix bupleuri mixing, soak about 30 minutes, separately take ginger and smash to pieces, place it in purple perilla, chaste tree
In the soak of mustard, windproof, folium isatidis and radix bupleuri, boiled rapidly with higher than 300 degrees Celsius intense fires, after to use 150-170 instead Celsius
It spends slow boiling to maintain, approximately passes through 20 minutes addition peppermints and continue, with being cooked by slow fire 10 minutes, to decoct and take liquid.
Application method:The proportioning of medicament and water is 1 when use:80, with hand stir evenly can balneation, after baby adapt to after
Water temperature is added to 43-45 degrees Celsius, each bathing 10-15 minutes, dabs whole body skin, perspiring slightly with baby is advisable, after bath
It need not be rinsed with clear water, when bathing keeps suitable indoor temperature, and plain boiled water is suitably drunk after bath.
The advantages of drug of the present invention is:The present invention is with purple perilla, schizonepeta, folium isatidis, windproof for main ingredient, radix bupleuri, peppermint, ginger
Be applied in combination for adjuvant, the synergistic effect between each drug can be given full play to, have non-stimulated, safety and comfort effectively, allotment it is simple,
Raw material simply easily takes and without side-effects, it is with strong points the advantages that, can effectively help to alleviate headache, nose caused by anemofrigid cold
The discomforts such as plug, runny nose.It is put in water-bath when use, the beneficiating ingredient of External absorbability can reach maximization, therefore the ratio that takes effect
Common drug treatment faster, avoids having an injection by pain, takes medicine and suffer hardships, reduce drug to mucous membrane of mouth and gastral stimulation and
Drug is directly entered the toxic action to liver, kidney and other organs after systemic circulation.
Each raw material pharmacological effect is respectively:
It is purple perilla, schizonepeta, windproof:Inducing sweat and dispelling exogenous evils are used for chill table disease, see the diseases such as aversion to cold, fever, lossless, often coordinate ginger
With use;
Folium isatidis:It is clearing heat and detoxicating;
Radix bupleuri:Inducing diaphoresis is brought down a fever;
Peppermint:Pharynx-clearing throat-benefiting;
Ginger:Cold dispelling sweating, preventing phlegm from forming and stopping coughing.
Specific implementation mode
The following describes the present invention further through the description of specific embodiments, but this is not the limit of the present invention
System, those skilled in the art's basic ideas according to the present invention can make various modifications or improvements, as long as but not falling off this
The basic thought of invention, is all within the scope of the present invention.
A kind of 1 preparation of the dedicated compound Chinese medicinal preparation of chill cold in children health care of the present invention of embodiment
Purple perilla, schizonepeta, windproof, folium isatidis and each 10 grams of mixing of radix bupleuri are taken, soaks about 30 minutes, separately takes ginger 10
Gram and smash to pieces, place it in the soak of purple perilla, schizonepeta, windproof, folium isatidis and radix bupleuri, boil rapidly with high heat, after use instead
Slow boiling maintains, and approximately passes through 20 minutes and 10 grams of peppermint is added, continue with being cooked by slow fire 10 minutes.
Experimental example
The anemofrigid cold infant being treated in our hospital outpatient department or hospitalized in May, 2,012 50 in June, 2011 is chosen,
Wherein man 25, female 25, infant average age be 2 one full year of life, have fever with aversion to cold, lossless, head-body-pain, nasal obstruction, watery nasal discharge,
The symptoms such as cough, sneezing.The above infant is randomly divided into treatment group and control group according to patient's admission time, every group each 25
Infant.Man 13, female 12 in treatment group;Man 12, female 13 in control group.To the gender of two groups of infants, age, symptom etc.
Basic document compares, no significant difference, p>0.05, it is comparable.
Therapy
To treatment group's infant by the dedicated compound Chinese medicinal preparation of chill cold in children health care of the 250ml embodiment of the present invention 1
It is added in 20L, balneation is stirred evenly with hand, water temperature is added to 43-45 degrees Celsius after infant adaptation, bathing 10-15 minutes, gently
Whole body skin is wiped, perspiring slightly with infant is advisable, and need not be rinsed with clear water after bath, and when bathing keeps suitable indoor temperature, bath
Plain boiled water is suitably drunk afterwards.3 times a day, 1 time 1 dose.Continuous use 4 days, treatment group's infant stops using other during the experiment
Water-bath health products.
Control group infant is treated using GANMAO QINGRE KELI, 3 times a day, once a bag, is used continuously 4 days, observation
Pretherapy and post-treatment body temperature, the situation of change of sign and adverse reaction.
Curative effect determinate standard
The therapeutic effect of two groups of infants is compared, wherein curing as after infant medication 4 days, symptom and sign disappears;It is aobvious
Effect is that symptom is substantially reduced after medication 4 days, and most of sign disappears;Effectively mitigate for symptom after medication 4 days, part sign disappears
It loses;Symptom and sign cannot be made to disappear after 4 days for medication in vain.Total effective rate is:[(curing number of cases+effective number of cases)/total example
Number] %.Two groups of infant skin lesion resume speeds are compared.
Statistical method
This experimental data carries out statistical analysis using SPSS13.0 softwares, and wherein measurement data comparison is examined using t,
Enumeration data comparison uses Chi-square Test, is that difference is statistically significant with p < 0.05.
Treatment results
Patient numbers;Male to female ratio | Cure number | Effective number | Significant figure | Invalid number | Total effective rate | |
Treatment group | 25(Man 13;Female 12) | 20 | 2 | 2 | 1 | 88% |
Control group | 25(Man 12;Female 13) | 12 | 8 | 3 | 2 | 80% |
25 infants for the treatment of group cure 20, and proportion 80.0%, effective 2, proportion 8.0% is total effective
Rate is 88.0%;25 infants of control group cure 12, and proportion 48.0%, effective 8, proportion 32.0% always has
Efficiency is 80.0%.Comparing result between two groups of infant therapeutic effects shows that the comparison between two groups of infant therapeutic effects is treated
Group is better than control group, containing statistically significant(p<0.05).According to statistical result, it can show that infant is a kind of using the present invention
The dedicated compound Chinese medicinal preparation treatment anemofrigid cold curative effect of chill cold in children health care more preferably conclusion.
Claims (3)
1. a kind of dedicated compound Chinese medicinal preparation of chill cold in children health care, it is characterised in that it is the original matched by following weight
Material composition:5-15 parts of purple perilla, 5-15 parts of schizonepeta, 5-15 parts of folium isatidis, 5-15 parts windproof, 5-15 parts of radix bupleuri, 5-15 parts of peppermint, life
5-15 parts of ginger;Its purposes is:The dedicated compound Chinese medicinal preparation of chill cold in children health care is put in water-bath, Neng Gouyou
Effect alleviates the discomforts such as headache, nasal obstruction, runny nose caused by anemofrigid cold.
2. a kind of dedicated compound Chinese medicinal preparation of chill cold in children health care according to claim 1, it is characterised in that it
The raw material matched by following weight forms:It is 10 parts of purple perilla, 10 parts of schizonepeta, 10 parts of folium isatidis, 10 parts windproof, 10 parts of radix bupleuri, thin
10 parts of lotus, 10 parts of ginger.
3. a kind of dedicated compound Chinese medicinal preparation of chill cold in children health care according to claim 1, mainly by following steps
Suddenly it is prepared:Purple perilla, schizonepeta, windproof, folium isatidis and radix bupleuri mixing are taken, is soaked about 30 minutes, is separately taken ginger and smash
It is broken, it places it in the soak of purple perilla, schizonepeta, windproof, folium isatidis and radix bupleuri, is boiled rapidly with the intense fire higher than 300 degrees Celsius
Boiling, after use 150-170 degrees Celsius of slow boiling instead and maintain, approximately pass through and peppermint is added within 20 minutes continues with being cooked by slow fire 10 minutes,
It decocts and takes liquid.
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CN104587334B (en) * | 2015-02-04 | 2017-09-15 | 吴自和 | A kind of traditional Chinese powder medicine for being used to treat anemofrigid cold |
CN105412383A (en) * | 2015-12-22 | 2016-03-23 | 路军贞 | Medicated bath bag for infantile wind-cold type common cold |
CN105853800A (en) * | 2016-05-24 | 2016-08-17 | 王桂英 | Traditional Chinese medicine for treating common cold due to wind-cold |
CN108704079A (en) * | 2018-08-20 | 2018-10-26 | 李时珍(广州)健康科技有限公司 | A kind of Traditional medicine bubble bath composition, preparation method and application improving cold in children fever symptoms |
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CN101982190A (en) * | 2010-10-20 | 2011-03-02 | 徐柔云 | External cream for treating wind cold by utilizing percutaneous absorption technology |
CN104027788A (en) * | 2014-06-30 | 2014-09-10 | 陈忠 | Traditional Chinese medicine composition for treating exogenous cold |
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