CN104887702A - Chinese medicinal composition for treating skin injury and ulceration and preparation method thereof - Google Patents
Chinese medicinal composition for treating skin injury and ulceration and preparation method thereof Download PDFInfo
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- CN104887702A CN104887702A CN201510278788.7A CN201510278788A CN104887702A CN 104887702 A CN104887702 A CN 104887702A CN 201510278788 A CN201510278788 A CN 201510278788A CN 104887702 A CN104887702 A CN 104887702A
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Abstract
The invention relates to a Chinese medicinal composition for treating skin injury and ulceration. The Chinese medicinal composition comprises 10-20 parts of borneol, 5-15 parts of potassium aluminium sulfate and 8-14 parts of gypsum. The invention further relates to a preparation method of powder and Chinese medicinal ointment. The Chinese medicinal composition has the advantages that the medicaments are synergistic, jointly achieve the effects of regenerating tissues to heal wound, diminishing swelling, inhibiting ulceration, stopping bleeding and festering, have strong targeting property on treatment based on syndrome differentiation, and can sterilize skin, diminish inflammation, accelerate wound healing and the like; the medicinal effects directly reach the focus; and the Chinese medicinal composition is mainly used for treating ulcerated skin injury, has quick response and short treatment course when being used for wound healing ulcerated injury, and has the characteristics of exact effect, no toxic or side effect, low cost and high cure rate.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind ofly can treat skin injury and Chinese medicine composition of festering and preparation method thereof.
Background technology
Defect caused by the destruction that skin ulceration is knitted for corium or deep skin.Skin ulceration is secondary lesion, every skin injury, infects or infringement that tuberosity ulceration reaches certain depth can cause the generation of skin ulceration.It is generally the limitation Skin preparation caused by wound, infected by microbes, tumor, circulatory disturbance and delayed ischemic neurological deficits, immunologic dysfunction or congenital skin injury etc.Traumatic skin festers and directly acts on tissue by physics and chemistry factor often and cause; Microbial infectious diseases is many causes disorganization by antibacterial, fungus, spirillum, virus etc.; The vasculitic skin ulceration system that dysimmunity causes is formed because tremulous pulse or arteriolitis make tissue necrose; Circulation or delayed ischemic neurological deficits belong to malnutrition and cause tissue necrosis, as varicosis, diabetic skin are festered.
Skin injury and this sick sickness rate that festers higher, though adult or child have generation more.At present, treatment skin injury and festering nothing more than the unguentum of Western medicine external, Chinese medicine or powder etc., its curative effect is not felt quite pleased.Western medicine is corrosive and there is certain side effect.There is weak curative effect in said medicine, take effect slow mostly, analgesic effect not obviously, the problem such as the strong and wound healing time of dissipating blood stasis for subsidence of swelling effect is long; And raw materials used medicine composition drug effect is single in the external used medicine of Chinese drug preparation, crude drug kind is more, and some raw material of Chinese medicine medicines and other crude drug synergism do not occur, and have impact on the overall curative effect of Chinese medicine composition.The present invention be directed to existing Chinese medicine and western medicine to the deficiency that in the treatment of this disease, hemostasis is slow, healing time is long, provide a kind of evident in efficacy, convenient and swift, cheap hemostasis fast, the Chinese medicine composition that healing stage is short.
Summary of the invention
In order to solve the problems referred to above that prior art exists, the invention provides a kind of hemostasis fast, the treatment skin injury that healing stage is short and the Chinese medicine composition that festers and preparation method thereof, its good effect has no side effect.
The technical solution adopted in the present invention is: a kind of Chinese medicine composition for the treatment of skin injury and festering, composed of the following components: Borneolum Syntheticum 10-20 part, raw vitriol 5-15 part, Gypsum Fibrosum 8-14 part.
The component of following weight portion is preferably included: component is Borneolum Syntheticum 10 parts, raw vitriol 5 parts, 8 parts, Gypsum Fibrosum in above-mentioned treatment skin injury and the Chinese medicine composition that festers.
The component of following weight portion is preferably included: Borneolum Syntheticum 15 parts, raw vitriol 10 parts, 12 parts, Gypsum Fibrosum in above-mentioned treatment skin injury and the Chinese medicine composition that festers.
The component of following weight portion is preferably included: Borneolum Syntheticum 20 parts, raw vitriol 15 parts, 14 parts, Gypsum Fibrosum in above-mentioned treatment skin injury and the Chinese medicine composition that festers.
The component of following weight portion is preferably included: Borneolum Syntheticum 12 parts, raw vitriol 15 parts, 13 parts, Gypsum Fibrosum in above-mentioned treatment skin injury and the Chinese medicine composition that festers.
The component of following weight portion is preferably included: Borneolum Syntheticum 18 parts, raw vitriol 6 parts, 9 parts, Gypsum Fibrosum in above-mentioned treatment skin injury and the Chinese medicine composition that festers.
Present invention also offers a kind of preparation containing Chinese medicine composition described above, described preparation is powder or Chinese medicinal ointment.Described powder is mainly used in treating skin injury, adds appropriate distilled water, make Chinese medicinal ointment in powder, and may be used for treating skin ulceration, described Chinese medicinal ointment comprises the powder of 10 weight portions and the distilled water of 1-5 weight portion.
Present invention also offers a kind of preparation method of preparation described above, it is characterized in that, comprise the following steps: parch that various medicated powder is heated respectively, weigh mix homogeneously by described proportioning; Preferably 200-300 degree is heated and is fried 15-20 minute.
Present invention also offers the application that a kind of Chinese medicine composition described above is treated skin injury in preparation and festered in medicine.
In the present invention, the pharmacological property of each raw material is as follows:
Borneolum Syntheticum: have another name called sheet brain, Fructus Citri tangerinae sheet, Blumeae preparatum Tabellae.Meridian distribution of property and flavor: acrid in the mouth, hardship, be slightly cold; GUIXIN, liver, lung meridian.Function cures mainly: have refreshment of having one's ideas straightened out, the loose poison of heat clearing away, and effect of improving acuity of vision and removing nebula cures mainly the loose poison of heat clearing away, effect of improving acuity of vision and removing nebula, cure mainly calentura unconsciousness due to high fever, apoplexy syncope due to accumulation of phlegm infantile convulsion, heat-damp in summer hoodwinks key clearly, and sore throat is deaf, aphtha tooth swells, carbuncle sore infantile malnutrition hemorrhoid, conjunctival congestion and swelling pain, pterygium.
Raw vitriol: meridian distribution of property and flavor: cold; Sour, puckery; Return lung, spleen, liver, large intestine channel.Function cures mainly: hemostasis, detumescence, external removing toxic substances parasite killing, dampness removing to stop itchin.
Gypsum Fibrosum: meridian distribution of property and flavor: sweet, pungent, in Great Cold, attaches to the lung and stomach meridians.Function cures mainly: clearing away heat-fire, and relieving restlessness is quenched the thirst.For fever caused by exogenous pathogenic factors, high hot excessive thirst, dyspnea and cough due to lung-heat, the high Sheng of stomach-fire, headache, toothache.
Beneficial effect of the present invention is: Chinese medicinal powder of the present invention and unguentum have effect of clearing away heat-fire, reducing swelling and alleviating pain, detoxification sore treatment.In crude drug of the present invention, Borneolum Syntheticum has effect of heat-clearing and toxic substances removing, reducing swelling and alleviating pain, cures mainly pyretic toxicity carbuncle; Raw vitriol has effect of dampness removing toxic substances, convergence, cures mainly aphtha of the mouth and tongue, curing ulcer erosion; Gypsum Fibrosum has effect of heat-clearing and toxic substances removing, pathogenic fire purging, convergence skin infection, cures mainly aphtha of the mouth and tongue, bursts and do not close up.
The present invention is a kind of unique new formulation, and contrasting this medicine with the existing external preparation for skin medicine sold on the market has following functions: 1, stop blooding fast.As knife injury, gunshot wound, scuffing, burn haemophilia, with hemostasis at once after this medicine.2, anti-inflammatory analgetic.Knife injury, gunshot wound, scuffing, wound is smeared this medicine, and without antiinflammatory such as medicine injections after stitching, 8-12 days all healeds, burning 30 days can rehabilitation.What 3, a variety of causes caused festers.Can treat that diabetes cause fester, sexually transmitted disease (STD) causes festers.Hospitals at Present and on the market this quasi drugs cure rate are very low, and this medicine by the various dermatoses all healed in 60 days that festers, can reduce the misery of patient.
The present invention adopts Borneolum Syntheticum, raw vitriol, the multiple medical material scientific combination of Gypsum Fibrosum, and each medicine supplements and complements each other, but plays promoting tissue regeneration and ulcer healing altogether, detumescence is festered, effect of arresting hemostasia and suppuration, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs targeting is comparatively strong, can inhibiting bacteria and diminishing inflammation, promotes wound healing etc., drug effect is gone directly focus, cure mainly skin injury and fester, being used for the treatment of skin injury and the instant effect that festers, short treating period, there is determined curative effect, have no side effect, cost is low, the feature that cure rate is high.Effective percentage 100%, cure rate more than 95%.
Detailed description of the invention
Below in conjunction with embodiment, further illustrate content of the present invention.Should be appreciated that enforcement of the present invention is not limited to the following examples, any pro forma accommodation make the present invention and/or change all will fall into scope.
In the present invention, if not refer in particular to, all parts, percentage ratio are unit of weight, and all equipment and raw material etc. all can be buied from market or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
Embodiment 1: a kind of Chinese medicine composition for the treatment of skin injury and festering, comprises following component: Borneolum Syntheticum 10g, raw vitriol 5g, Gypsum Fibrosum 8g.
Embodiment 2: a kind of Chinese medicine composition for the treatment of skin injury and festering, comprises following component: Borneolum Syntheticum 15g, raw vitriol 10g, Gypsum Fibrosum 12g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of skin injury and festering, comprises following component: Borneolum Syntheticum 20g, raw vitriol 15g, Gypsum Fibrosum 14g.
Embodiment 4: a kind of Chinese medicine composition for the treatment of skin injury and festering, comprises following component: Borneolum Syntheticum 12g, raw all 15g, Gypsum Fibrosum 13g.
Embodiment 5: a kind of Chinese medicine composition for the treatment of skin injury and festering, comprises following component: Borneolum Syntheticum 18g, raw all 6g, Gypsum Fibrosum 9g.
Wherein the preparation method of embodiment 1-5 includes following steps: by various medicated powder respectively 200-300 degree heat and fry 15-20 minute, weigh mix homogeneously by described proportioning.
Injure the Chinese medicine composition festered outside treatment chronic skin of the present invention, clinical efficacy is summed up:
One, samples selection
The present invention is in clinical case 150 example, and man 80 example, female 70 example, at 5 years old-50 years old age, the shortest person of the course of disease 1 day, most elder reaches 35 days.Be divided into two groups at random, treatment group 100 people, male 55 people, women 45 people; Matched group 50 people, male 25 people, women 25 people.Usage and dosage: use five floricomes to puncture affected part, is coated with medicine on skin ulcer face, every day 2 times.All case observations are to accepting only to have treated February.If cure, stop treatment therebetween.According to the chapter 13 first segment of the 6th edition " surgery " teaching material in People's Health Publisher, clinical manifestation and diagnosis in burn surface area and depth standards classification, burn degree is divided into gently, in, severe 3 class.In 150 routine cases, minor burn 74 example, moderate burn 72 example, severe burn 4 example.
Two, Therapeutic Method
If wound, be coated with in wound and spill medicated powder, the disposable recovery from illness of the lighter, severe one changes at most three medicines.If affected part saline is cleaned, then at wound smearing ointment by the outer wound response of skin ulceration.Within one day, be coated with 2 times.
Matched group 1-patient 50 example, medication-Chinese medicinal ointment Borneolum Syntheticum 20g, raw vitriol 15g.Usage and dosage: be applied on the skin ulcer face of skin ulceration, every day 2 times.
Matched group 2---patient 50 example, medication-Chinese medicinal ointment Borneolum Syntheticum 20g, Gypsum Fibrosum 15g.Usage and dosage: get Chinese medicinal ointment of the present invention and be applied on the skin ulcer face of skin ulceration, every day 2 times.
Treatment group 2---patient 50 example, Chinese medicinal ointment Borneolum Syntheticum 15g, raw vitriol 10g, Gypsum Fibrosum 12g in medication-embodiment 2.Usage and dosage: get Chinese medicinal ointment of the present invention and be applied on the skin ulcer face of skin ulceration, every day 2 times.
Three, standard is treated:
Cure: wound surface heals completely, slight 6 days, moderate 16 days, severe 32 days, burn wound healing person in regulation healing time.
Effective: in regulation healing time, burn wound reduces, but not healing person completely.
Invalid: the burn wound that exceeds schedule time is not any change.
Four, therapeutic effect: in this clinical observation case, most elder's medication 40 days
Treatment group 1: cure rate 95%; Effective percentage 100%; Inefficiency 0%.
Matched group 1: cure rate 70%; Effective percentage 75%; Inefficiency 25%.
Matched group 2: cure rate 67%; Effective percentage 70%; Inefficiency 30%.
Conclusion:
The cure rate of Chinese medicinal ointment treatment burn prepared by the embodiment of the present invention 2 is 95%, and total effective rate is 100%, its 95% confidence interval 90-100%.Illustrate that externally-applied medicinal composition prepared by the embodiment of the present invention 1 is all burnt definite curative effect.
Five, concrete case
Case 1: Nenjiang town, Nenjiang County, Heilongjiang Province Zhang, 40 years old, trouble diabetes cause festered, obstinate, and having sought all over national various big hospital can not cure the disease, and requires amputation, treats 40 days with this medicine, recovery from illness, has worked as usual after disease is good.
Case 2: Nenjiang County, Heilongjiang Province Mrs Qu, female 50 years old, what dermatosis caused festers all over the body, and all parts of the country have been gone over, and comprises various big hospital and all cannot cure for 3 years, and through treating a wheat harvesting period with this medicine, patient returns to one's perfect health.
Case 3: Mrs Fu, female 50 years old, rear cattle of being in, during hand hay cutter grass, accidentally cutting half section by hands, broken bone half, through treating with this medicine, within 28 days, returning to one's perfect health.
Case 4: Mrs Liu, 26 years old, plane abdomen puerperal, still disunion wound half a year, through treating with this medicine, sealing recovery from illness after month.
In sum, matched group 1, matched group 2 all have notable difference with treatment group in curative effect.Treatment group good effect, time are short, also save expense so simultaneously.Therefore, Chinese medicinal ointment of the present invention be as good as be a kind of effect, honest and clean, just, prompt treatment skin injury and the Chinese medicine preparation that festers.
The present invention is not limited to above-mentioned preferred forms; anyone can draw other various forms of products under enlightenment of the present invention; no matter but any change is done in its shape or structure; every have identical with the application or akin technical scheme, all drops within protection scope of the present invention.
Claims (10)
1. the Chinese medicine composition for the treatment of skin injury and festering, is characterized in that, comprises the component of following weight portion: Borneolum Syntheticum 10-20 part, raw vitriol 5-15 part, Gypsum Fibrosum 8-14 part.
2. a kind of Chinese medicine composition for the treatment of skin injury and festering according to claim 1, is characterized in that, component is Borneolum Syntheticum 10 parts, raw all 5 parts, 8 parts, Gypsum Fibrosum.
3. a kind of Chinese medicine composition for the treatment of skin injury and festering according to claim 1, it is characterized in that, component is: Borneolum Syntheticum 15 parts, raw all 10 parts, 12 parts, Gypsum Fibrosum.
4. a kind of Chinese medicine composition for the treatment of skin injury and festering according to claim 1, it is characterized in that, component is: Borneolum Syntheticum 20 parts, raw vitriol 15 parts, 14 parts, Gypsum Fibrosum.
5. a kind of Chinese medicine composition for the treatment of skin injury and festering according to claim 1, it is characterized in that, component is: Borneolum Syntheticum 12 parts, raw vitriol 15 parts, 13 parts, Gypsum Fibrosum.
6. a kind of Chinese medicine composition for the treatment of skin injury and festering according to claim 1, it is characterized in that, component is: Borneolum Syntheticum 18 parts, raw vitriol 6 parts, 9 parts, Gypsum Fibrosum.
7. containing, for example a preparation for the described Chinese medicine composition of one of claim 1-6, it is characterized in that, described preparation is powder type Chinese medicinal ointment.
8. a preparation method for preparation described in claim 7, is characterized in that, comprises the following steps: parch of being heated respectively by various medicated powder, weighs mix homogeneously by described proportioning.
9. preparation method according to claim 8, is characterized in that, described in the heat temperature of parch be 200-300 degree, the time is 15-20 minute.
10. the application that Chinese medicine composition is treated skin injury in preparation and festered in medicine as described in one of claim 1-6.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108159128A (en) * | 2017-12-22 | 2018-06-15 | 普汝保 | Chinese medicine composition for skin injury and its preparation method and application and the Chinese medicine composition to fester for mucous membrane and its application |
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2015
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Patent Citations (2)
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CN1048325A (en) * | 1990-07-25 | 1991-01-09 | 吴光忠 | The preparation method of skin ointment for healing ulcered wound |
CN1742859A (en) * | 2004-09-02 | 2006-03-08 | 周长居 | Medicinal ointment for regenerating-repairing burn and scald |
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侯桂芝等: "冰片对激光烧伤创面的镇痛及抗炎作用", 《中国药学杂志》 * |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108159128A (en) * | 2017-12-22 | 2018-06-15 | 普汝保 | Chinese medicine composition for skin injury and its preparation method and application and the Chinese medicine composition to fester for mucous membrane and its application |
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