CN108310320A - A kind of externally applied drug and preparation method thereof for treating gout - Google Patents
A kind of externally applied drug and preparation method thereof for treating gout Download PDFInfo
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Abstract
The present invention relates to a kind of externally applied drugs and preparation method thereof for treating gout, the externally applied drug includes turmeric, rheum officinale, Cortex Phellodendri, root of Chinese trichosanthes, unprocessed Arisaema erubescens, windproof, Chinese ephedra, the root of Dahurain angelica, frankincense, myrrh, dragon's blood, safflower, more than ground bettle 13 taste medicines, and production method is as follows：S1：Each ingredient in external used medicine is ground into smalls, is sieved, crude drug is made in mixing；S2：Appropriate vaseline is put into dispensing ware, is heated to 80 °, until melting completely；S3：Medicinal powder is added in dispensing ware, and is stirred continuously to uniformly mixed；S4：Stirring in mixture is added in qs glycerin, and, to being uniformly mixed, cooling is filling to obtain external used medicine finished product.This medicine can not only play the role of anti-inflammatory sterilization, anti-infective, elimination swelling and analgesic and also have stronger activating macrophage, increase the effect of its immune phagocytic function, the medicine ingredient is relatively simple, makes simple, the effect for treating gout is good, therefore has preferable promotional value.
Description
Technical field
The present invention relates to pharmaceutical technology fields, and in particular to a kind of external used medicine and preparation method thereof for treating gout.
Background technology
Gout is by monosodium urate salt（MSU）Deposition caused by crystal correlation arthropathy, with purine metabolic disturbance and
（Or）Hyperuricemia caused by underexcretion is directly related, refers in particular to acute characteristic arthritis and chronic gout stone disease
Disease includes mainly acute attack arthritis, tophus formation, tophaceous chornic arthritis, urate nephropathy and uric acid
Lithangiuria, severe one may occur in which joint deformity and renal insufficiency.
Surgery recipe ruyi jinhuang powder, ruyi jinhuang san is seen earliest written by Ming Dynasty's Chen Shigong《Surgery is authentic》, there is heat-clearing dissipating bind, detumescence
The effect of analgesic, removing toxic substances row's stasis of blood, for damp and hot turbid malicious stasis blocking skin muscles and bones, with the passing of time so that sore, swelling and pain and erysipelas symptoms include stasis blocking
Position is rubescent, swelling, excess heat, pain are acute.The present invention is that the externally used paste of gout is treated made of being improved according to ruyi jinhuang powder, ruyi jinhuang san.
Invention content
The main object of the present invention is to provide a kind of preparation method of external used medicine that treating gout, includes the following steps：
S1：Each ingredient in external used medicine is ground into smalls, is sieved, crude drug powder is made in mixing；
S2：Appropriate vaseline is put into dispensing ware, is heated to 80 °, until melting completely；
S3：Crude drug powder is added in dispensing ware, and is stirred continuously to being uniformly mixed, mixture is obtained；
S4：Stirring in mixture is added in qs glycerin, and, to being uniformly mixed, cooling is filling to obtain external used medicine finished product；
Wherein, in step sl, the external used medicine includes rheum officinale, Cortex Phellodendri, turmeric, rhizoma arisaematis, frankincense, myrrh, root of Chinese trichosanthes,
And in terms of mass fraction, the rheum officinale, Cortex Phellodendri are between 30-60 parts, and the turmeric, frankincense, myrrh are between 20-35 parts, institute
Rhizoma arisaematis, root of Chinese trichosanthes are stated between 55-65 parts.
Wherein, in step sl, external used medicine includes rheum officinale, Cortex Phellodendri, turmeric, rhizoma arisaematis, frankincense, myrrh, root of Chinese trichosanthes, and
In terms of mass fraction, rheum officinale, Cortex Phellodendri are between 32-42 parts, and turmeric, frankincense, myrrh are between 20-35 parts, rhizoma arisaematis, root of Chinese trichosanthes
Between 55-65 parts.
The preferred scheme of the present invention is that in step sl, external used medicine further includes dragon's blood, safflower and ground beetle
Worm.
The present invention a preferred scheme be, in step sl, in terms of mass fraction, in the external used medicine respectively at
Point content is respectively：Rheum officinale, Cortex Phellodendri are between 32-42 parts, and the turmeric, frankincense, myrrh, safflower, ground bettle are between 20-35
Part, the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood are between 55-65 parts.
The preferred scheme of the present invention is that in step sl, the external used medicine further includes the root of Dahurain angelica, windproof and numb
It is yellow.
The present invention a preferred scheme be, in step sl, in terms of mass fraction, each group in the external used medicine
Point content is：The rheum officinale, Cortex Phellodendri are between 32-42 parts, and the turmeric, frankincense, myrrh, the root of Dahurain angelica, Chinese ephedra are between 20-35
Part, it is the rhizoma arisaematis, root of Chinese trichosanthes, windproof between 55-65 parts.
The preferred scheme of the present invention is that in step sl, the external used medicine further includes dragon's blood, safflower, soil
Soft-shelled turtle worm, the root of Dahurain angelica, windproof and Chinese ephedra.
The present invention a preferred scheme be, in step sl, in terms of mass fraction, each ingredient of external used medicine
Content be rheum officinale, Cortex Phellodendri between 32-42 parts, the turmeric, frankincense, myrrh, safflower, ground bettle, the root of Dahurain angelica, Chinese ephedra between
It is 20-35 parts, the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood, windproof between 55-65 parts.
The preferred scheme of the present invention is that in terms of mass fraction, the ratio of the glycerine and the vaseline is
1:2-2:5。
The present invention also provides a kind of external used medicine for treating gout, it is prepared by above-mentioned any preparation method
's.
Beneficial effects of the present invention are as follows：
The externally applied drug for the treatment of gout provided by the invention can not only play anti-inflammatory sterilization, anti-infective, elimination swelling and analgesic and make
With also stronger activating macrophage increases the effect of its immune phagocytic function.
Specific implementation mode
The following is a clear and complete description of the technical scheme in the embodiments of the invention.It illustrates in the following description
Many details to facilitate a thorough understanding of the present invention, still the present invention can also use other be different from it is described here its
Its mode is implemented, and those skilled in the art can do similar popularization, therefore this hair without violating the connotation of the present invention
It is bright not limited by following public specific embodiment.
The indication that drug provided by the present invention is directed to is；Urarthritis patient, especially urarthritis
The damp and hot rheumatism patient of acute attack stage, specific symptom are：Primary symptom：There is rubescent color of the leather, arthroncus, joint hair in lower limb Minor articulus
Heat, arthralgia, and pain can not be touched, that touches is scorching hot, and joint motion is unfavorable.Minor symptom：Fever, it is thirsty, have the fidgets, urine is urinated Huang
Equal diseases.Tongue vein：Tongue nature is slightly red or dark red, yellow tongue fur or yellow greasy, slippery and rapid pulse or chord number.
It is provided by the invention treatment gout the main ingredient of external used medicine be rheum officinale, Cortex Phellodendri, turmeric, rhizoma arisaematis, frankincense,
Myrrh, root of Chinese trichosanthes.Wherein, rheum officinale clearing heat and cooling blood, the removing toxic substances row stasis of blood；Cortex Phellodendri heat-clearing and damp-drying drug, purging intense heat and detonicating；Turmeric blood-activating and qi-promoting leads to
Meridian and relieving pain；Rhizoma arisaematis is eliminating dampness and eliminating phlegm, dispersing swelling and dissipating binds；Frankincense, myrrh can promoting blood circulation and stopping pain, detumescence and promoting granulations；Root of Chinese trichosanthes clearing heat-fire
And detoxify, detumescence and apocenosis is to treat sore, specifically：
Rheum officinale：It is bitter in taste, tremble with fear, returns spleen, stomach, large intestine, liver, pericardium channel, have rush down clearly it is damp and hot, the effect of removing pattogenic heat from the blood and toxic material from the body, Stasis through.
Pharmaceutical research find, rheum officinale has rush down under, hemostasis, resisting pathogenic microbes, it is anti-inflammatory, antitumor, anti-oxidant the effects that, be related to disappearing
Multiple systems such as change, blood, uropoiesis, immune.
Cortex Phellodendri：It is bitter in taste, tremble with fear, return kidney, bladder, large intestine channel, can heat-clearing and damp-drying drug and purging intense heat and detonicating, with control sore swell
Poison.Pharmacological research Cortex Phellodendri has many effects such as antibacterial, antibechic, decompression and anti-oxidant, antigout, anticancer.
Turmeric：It is pungent, bitter for the dry rhizome of zingiberaceous plant turmeric, temperature, Return liver, the spleen channel, it is simultaneous enter blood system and qi leel, have work
The effect of blood promoting qi circulation and relieving pain, and be longer than row limb arm and remove numbness pain.Turmeric in pharmaceutical research turmeric is known as anti-inflammatory effect, can
Mitigate the synovial membrane inflammation reaction in joint.
Rhizoma arisaematis：It is bitter in taste, acrid in flavour and warm in nature, toxic, return lung, liver, the spleen channel, external application energy mass dissipating and swelling eliminating.Pharmaceutical research rhizoma arisaematis
Have it is anti-inflammatory, analgesia, eliminating the phlegm and it is antitumor the effects that.
Frankincense and myrrh are common medicines pair, and the two is resin.Frankincense, pungent, bitter, temperature, the thoughts of returning home, liver, the spleen channel, frankincense element
There is the title of traumatology Radix Notoginseng, there is the effect of promoting blood circulation to remove blood stasis, the carbuncle that disappears analgesic, saprophytic removing, detoxicating and resolving a mass.Myrrh, it is pungent, bitter, it puts down, returns
The heart, liver, the spleen channel are good at dissipation hemostasis, take into account detumescence and promoting granulation.Pharmacological research frankincense have analgesia, anti-inflammatory, increasing leukocyte work
With, and inflammatory seep can be accelerated to drain, promote wound healing, myrrh have bring down a fever, be anti-inflammatory, analgesia, the various aspects such as neuroprotection
Pharmacological activity, and non-evident effect.
Root of Chinese trichosanthes：Nature and flavor are sweet, slight bitter, are slightly cold, attach to the lung and stomach meridians.Clearing heat-fire and detoxify, detumescence and apocenosis is to treat sore.Pharmacology
Learning research root of Chinese trichosanthes has a variety of pharmacological activity such as hypoglycemic, antitumor, anti-inflammatory, antiviral and blood coagulation.
The present invention by research experiment, filtered out from the drugs of many treatment gouts rheum officinale, Cortex Phellodendri, turmeric, rhizoma arisaematis,
The major pharmaceutical component of frankincense, myrrh, root of Chinese trichosanthes as treatment gout.Bitter and cold medicines are followed when inventor makes up a prescription and pungent-warm medicine is same
With, also mixed with the traditional Chinese medicine ingredients being slightly cold, while the effect by two kinds of frankincense and myrrh to medicine, make the drug obtained by the present invention
There is more preferable curative effect in terms of promoting blood circulation to remove blood stasis, saprophytic removing, is proved through inventor's experimental study：When containing between above-mentioned each ingredient
When amount is following content, various traditional Chinese medicine ingredients can be made to play preferable effect：Rheum officinale, Cortex Phellodendri are between 32-42 parts, turmeric, breast
Fragrant, myrrh is between 20-35 parts, and rhizoma arisaematis, root of Chinese trichosanthes are between 55-65 parts.
In addition, the scheme that the present invention is shared using dragon's blood, safflower, three medicine of ground bettle, this three kinds of medicines share logical with promoting blood circulation
Through, the effect of scattered stasis pain, specifically：
Safflower：Nature and flavor are pungent, warm-natured, converge to heart and liver channels.Gas perfume (or spice) row dissipates, and entering blood system has the effect of invigorate blood circulation, stasis-dispelling and pain-killing.Medicine
Reason research safflower has the multiple efficacies such as anti-freezing, anti-inflammatory and analgesia, calmness.
Dragon's blood：Property sweet-salty, put down.Enter the heart, Liver Channel.There are scattered stasis pain, hemostasia and promoting granulation.Control traumatic injury, internal injury stasis caused pain；Outside
Hinder haemophilia, scrofula, ulcer on the shank is burst the effect of not conforming to long.Pharmacological research dragon's blood has and improves microcirculation, analgesia, hemostasis, anti-inflammatory
And promote the multiple efficacies such as epidermis reparation.
Ground bettle：Nature and flavor are salty, cold in nature.Return liver warp.Ground bettle has the effect of dissipating blood stasis with potent drugs, reunion of fractured tendons and bones.For bruise
Damage, injury of tendon and muscle fracture, blood stasis, postpartum stasis abdominal pain, addiction lump in the abdomen lump in the abdomen.Pharmacological research ground bettle have anticoagulation, antithrombotic,
Protect endothelial cell and other effects.
This three tastes medicine of safflower, dragon's blood, ground bettle, which shares, to be made pungent, cold all, coordinates above-mentioned main component, when using as follows
When formula, this externally applied drug effect can be made more preferable, and be more conducive to invigorate blood circulation, scattered stasis pain：In terms of mass fraction, greatly
Yellow, Cortex Phellodendri is between 30-60 parts（Preferably 32-42 parts, alternatively, taking 45-55 parts）, the turmeric, frankincense, myrrh, safflower, soil
Soft-shelled turtle worm is between 20-35 parts, and the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood are between 55-65 parts.
Three kinds of expelling wind drug roots of Dahurain angelica of utilization that the present invention also has characteristic, windproof, Chinese ephedra, wherein root of Dahurain angelica compatibility it is windproof can wind-dispelling it is dry
It is wet, while the root of Dahurain angelica again can dissipating bind Apocenosis pain relieving；Chinese ephedra diaphoresis with drugs pungent in flavor and warm in nature loosing the interspaces of skin and muscles, further can promote the efficacy of a drug to reach, while can profit
Water is subsided a swelling.The externally applied drug of the treatment gout of the present invention（Gout plaster）According to Chinese medicine pharmacology, when treating this disease of gout, although bitter cold
Medicine and the same use of pungent-warm medicine, but bitter cold pharmaceutical quantities should be greater than pungent-warm medicine, that is, based on bitter cold, help with the medicine of pungent-warm, specifically
's：
Chinese ephedra：Nature and flavor are pungent, slight bitter, temperature.Distributed in lung channel, bladder warp.Chinese ephedra has inducing sweat and dispelling exogenous evils, freeings lung and relieving asthma, the work(of inducing diuresis for removing edema
Effect.It is real to cure mainly typhoid fever table, fever with chilliness is lossless, headache nasal obstruction, arthralgia；Cough and asthma；Geomantic omen edema, difficult urination；Wind
Evil stupid numbness, munbness, rubella itch.Pharmacological research shows that Chinese ephedra has sweating, antipyretic, anti-inflammatory, diuresis, a variety of work(such as relieving asthma
Effect.
The root of Dahurain angelica：Nature and flavor are acrid in flavour and warm in nature, return lung, stomach, large intestine channel, can dispel pathogenic wind and remove dampness and dissipating bind Apocenosis pain relieving.Pharmacological research
It was found that the root of Dahurain angelica not only has antipyretic, analgesia, anti-inflammatory effect, also can be used to treat leucoderma and psoriasis.
Specifically, in terms of mass fraction, when each component content is following, preferably effect can be played：Rheum officinale, Cortex Phellodendri are equal
Between 32-42 parts, the turmeric, frankincense, myrrh, the root of Dahurain angelica, Chinese ephedra are the rhizoma arisaematis, root of Chinese trichosanthes, windproof between 20-35 parts
Between 55-65 parts.
It is optimal, according to inventor by long-time research experiment, a kind of gout for the treatment of is summed up from many make up a prescription
The more optimal solution made up a prescription, in terms of mass fraction, the content of each component is as follows：Rheum officinale, Cortex Phellodendri are between 32-42 parts, the ginger
Huang, frankincense, myrrh, safflower, ground bettle, the root of Dahurain angelica, Chinese ephedra between 20-35 parts, the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood, it is windproof
Between 55-65 parts.
Full side is taken a broad view of, though bitter and cold medicines and the same use of pungent-warm medicine, the dosage of right bitter and cold medicines is more than pungent-warm medicine, based on bitter cold, assistant
With the medicine of pungent-warm, so because " all sufferings sores, come under the heart（Fire）", sore swell and ache curative is a lot of from burning hot heresy, method answer clear purging intense heat heat,
Attack malicious dehumidifying, it is right " all sores are formed because of qi and blood stagnation ", therefore when treating, cold and cool medicine it is too many to enumerate with it, to prevent " ice coagulates flesh
It is meat muscles and bones, cause difficult rotten difficulties to hold back more ", treatment is then appropriate with this prescription when with the warm drugs carbuncle that dissipates that its stasis of blood is stagnant, the turbid poison that pulls out its, promoting blood circulation disappear
When being.Modern pharmacology experiment points out that such compatibility can not only play anti-inflammatory sterilization, anti-infective, elimination swelling and analgesic
Effect, also stronger activating macrophage increase the effect of its immune phagocytic function.
In order to preferably make the external used medicine for the treatment of gout provided by the present invention, the present invention also provides prepare this to control
The method for treating the external used medicine of gout：
S1：Take turmeric, rheum officinale, Cortex Phellodendri, root of Chinese trichosanthes, unprocessed Arisaema erubescens, windproof, Chinese ephedra, the root of Dahurain angelica, frankincense, myrrh, dragon's blood, safflower, soil
More than soft-shelled turtle worm 13 taste medicine is ground into smalls, crosses 120 mesh sieve, and crude drug is made in mixing, preferably, in terms of mass fraction, each component
Content is as follows：Between 32-42 parts, the turmeric, frankincense, myrrh, safflower, ground bettle, the root of Dahurain angelica, Chinese ephedra are situated between for rheum officinale, Cortex Phellodendri
It is the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood, windproof between 55-65 parts in 20-35 parts.
S2：In terms of mass fraction, 2800-3200 parts of vaseline are put into dispensing ware, are heated to 80 °, until melting completely；
S3：Above-mentioned manufactured crude drug powder is added in dispensing ware, and is stirred continuously to uniformly mixed；
S4：In terms of mass fraction, stirring is added in mixtures to being uniformly mixed in 1200-1600 parts of glycerine, it is cooling, it is filling to obtain the final product
To external used medicine finished product（When making the drug, in terms of mass fraction, the glycerine of addition and the ratio of vaseline are 1:2-2:
5）.
The use of this externally applied drug made from the above method is cement paste, when use directly appropriate even application affected part, then use
Cotton pad covers, and is fastened with bandage, is dismountable cleaning affected part after continuous use 24-48h.
Inventor is commented by ESR, CRP, UA, VAS of acute gouty arthritis patient after observation gout pasting exterior-applied therapeutic
Point, the variations of the indexs such as Clinical symptom and sign, to assess the Clinical efficacy and safety of gout plaster.
Method：Acute gouty arthritis patient 120 will be diagnosed as and be randomly divided into treatment group and control group, every group each
60.Control group gives colchicines tablets（0.5mg po tid）；Treatment group adds on the basis of giving colchicin and uses gout plaster
It is applied with lesion joint.Every group of course for the treatment of is 1 week.Observe pretherapy and post-treatment ESR, CRP, UA, VAS scoring of two groups of patients, clinic
The variation of the indexs such as symptom integral, clinical efficacy, adverse reaction.
As a result：Baseline index between (1) two group there are no significant difference（P ＞ 0.05）.（2）ESR, CRP of two groups of patients,
VAS scores before the treatment without significant difference（P ＞ 0.05）.Before ESR, CRP, VAS scoring of two groups of patients is relatively treated after treatment
There is significant decrease（P ＜ 0.05）, and the reduction degree for the treatment of group becomes apparent compared with control group（P ＜ 0.05）.(3) two groups of patients'
UA levels are before the treatment without significant difference（P ＞ 0.05）.Two groups of patient's serum uric acid levels reduce before relatively treating after treatment（P ＜
0.05）, but there was no significant difference compared with control group for the blood uric acid fall for the treatment of group（P ＞ 0.05）.It is clinical before (4) two groups of treatments
Symptom integral compares, no significant difference（P ＞ 0.05）；Clinical symptoms integral after two groups of treatments reduces before relatively treating
（P ＜ 0.05）；And clinical symptoms integral is significantly lower than control group after the treatment for the treatment of group, difference is statistically significant（P ＜
0.05）.Conclusion：Gout plaster can reduce the inflammation index of acute gouty arthritis patient, VAS scorings, clinical symptoms integral；
Gout plaster combines western medicine acute gouty arthritis patient has apparent clinic compared with simple western medicine；Gout plaster treats acute pain
Wind arthritis is safe and effective, is worthy to be popularized, and can become a kind of effective Chinese traditional treatment method.
In the present invention, so-called ESR refers to erythrocyte sedimentation rate (ESR).
In the present invention, so-called CRP refers to C reactive proteins.
In the present invention, so-called VAS refers to visual analogue scales.
In the present invention, so-called UA refers to blood uric acid.
Obviously, described embodiment is only a part of the embodiment of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Claims (10)
1. a kind of preparation method of external used medicine that treating gout, which is characterized in that include the following steps：
S1：Each ingredient in external used medicine is ground into smalls, is sieved, crude drug powder is made in mixing；
S2：Appropriate vaseline is put into dispensing ware, is heated to 80 °, until melting completely；
S3：Crude drug powder is added in dispensing ware, and is stirred continuously to being uniformly mixed, mixture is obtained；
S4：Stirring in mixture is added in qs glycerin, and, to being uniformly mixed, cooling is filling to obtain external used medicine finished product；
Wherein, in step sl, the external used medicine includes rheum officinale, Cortex Phellodendri, turmeric, rhizoma arisaematis, frankincense, myrrh, root of Chinese trichosanthes,
And in terms of mass fraction, the rheum officinale, Cortex Phellodendri are between 30-60 parts, and the turmeric, frankincense, myrrh are between 20-35 parts, institute
Rhizoma arisaematis, root of Chinese trichosanthes are stated between 55-65 parts.
2. the preparation method of the external used medicine for the treatment of gout according to claim 1, which is characterized in that in step sl,
The external used medicine includes rheum officinale, Cortex Phellodendri, turmeric, rhizoma arisaematis, frankincense, myrrh, root of Chinese trichosanthes, and in terms of mass fraction, described
Rheum officinale, Cortex Phellodendri are between 32-42 parts, and between 20-35 parts, the rhizoma arisaematis, root of Chinese trichosanthes are situated between for the turmeric, frankincense, myrrh
In 55-65 parts.
3. the preparation method of the external used medicine for the treatment of gout according to claim 1 or 2, which is characterized in that in the step
In rapid S1, the external used medicine further includes dragon's blood, safflower and ground bettle.
4. the preparation method of the external used medicine for the treatment of gout according to claim 3, which is characterized in that in step sl,
In terms of mass fraction, each component content is respectively in the external used medicine：Rheum officinale, Cortex Phellodendri between 32-42 parts, the turmeric,
Frankincense, myrrh, safflower, ground bettle are between 20-35 parts, and the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood are between 55-65 parts.
5. the preparation method of the external used medicine for the treatment of gout according to claim 1 or 2, which is characterized in that in step S1
In, the external used medicine further includes the root of Dahurain angelica, windproof and Chinese ephedra.
6. the preparation method of the external used medicine for the treatment of gout according to claim 5, which is characterized in that in step sl,
In terms of mass fraction, each component content is in the external used medicine：The rheum officinale, Cortex Phellodendri between 32-42 parts, the turmeric,
Frankincense, myrrh, the root of Dahurain angelica, Chinese ephedra are the rhizoma arisaematis, root of Chinese trichosanthes, windproof between 55-65 parts between 20-35 parts.
7. the preparation method of the external used medicine for the treatment of gout according to claim 1 or 2, which is characterized in that in step S1
In, the external used medicine further includes dragon's blood, safflower, ground bettle, the root of Dahurain angelica, windproof and Chinese ephedra.
8. the preparation method of the external used medicine for the treatment of gout according to claim 7, which is characterized in that in step sl,
In terms of mass fraction, the content of each ingredient of external used medicine is rheum officinale, Cortex Phellodendri between 32-42 parts, the turmeric, frankincense,
Myrrh, safflower, ground bettle, the root of Dahurain angelica, Chinese ephedra are the rhizoma arisaematis, root of Chinese trichosanthes, dragon's blood, windproof between 55- between 20-35 parts
65 parts.
9. the preparation method of the external used medicine for the treatment of gout according to claim 1 or 2, which is characterized in that with mass parts
The ratio of number meter, the glycerine and the vaseline is 1:2-2:5.
10. a kind of external used medicine for treating gout, which is characterized in that by the preparation of any one of claim 1-9 preparation methods
At.
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| CN113144095A (en) * | 2020-01-07 | 2021-07-23 | 成都医学院 | Pharmaceutical composition for treating gouty arthritis and preparation method and application thereof |
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Application publication date: 20180724 |