CN106334034A - Traditional Chinese medicine compositon, nose drop containing same and application thereof - Google Patents
Traditional Chinese medicine compositon, nose drop containing same and application thereof Download PDFInfo
- Publication number
- CN106334034A CN106334034A CN201610893618.4A CN201610893618A CN106334034A CN 106334034 A CN106334034 A CN 106334034A CN 201610893618 A CN201610893618 A CN 201610893618A CN 106334034 A CN106334034 A CN 106334034A
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- China
- Prior art keywords
- chinese medicine
- lignum aquilariae
- aquilariae resinatum
- compositionss
- preparation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
- A61K36/835—Aquilaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, a nose drop containing the same and application thereof. The traditional Chinese medicine nose drop is made of, by weight, 2-4 parts of agarwood, 1-5 parts of xanthium sibiricum and 1-4 parts of mint. The traditional Chinese medicine nose drop not only has effects of antisepsis and anti-inflammation and nasal mucosa protection, but also has effects of calming the nerves and relieving fatigue, and has fewer side effects.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly to Chinese medicine composition, the nasal drop containing this Chinese medicine composition and its should
With.
Background technology
Rhinitis is the inflammation of nasal membrane and submucous tissue, shows as hyperemia or edema.Patient often occur nasal obstruction,
The diseases such as rhinorrhea rhinocnesmus, throat's discomfort, cough, sneeze.It is because chronic or acute nasal mucosa as virus, courses of infection or
Irritating effect is impaired caused.Obstinate even causes rhinocarcinoma, some patients with rhinitis's hypertrophic inferior turbinates, and during sleep, oxygen is not
Foot, causes cerebral infarction, hypertension, heart attack when serious, or even sudden death, and domestic 300,000,000 populations that there are about are perplexed by rhinitis.
At present, adopting Western medicine local treatment clinical treatment rhinitis more, and nasal cavity triumph structure more than Western medicine, can be destroyed, at a specified future date
Curative effect is unsatisfactory, and side effect is more, and particularly antibiotic etc. easily makes pathogenic bacteria develop immunity to drugs.For example on market common
The good Naphazoline Chloridum collunarium drop of effectiveness comparison, frequent medication easily causes rebound nasal congestion, can also result in Drug nose
Inflammation, has slight burn feeling, prickling sensation, nasal mucosa is dried and the side effect such as headache, dizziness, increased heart rate is larger after medication.
The Therapeutic Method of existing Chinese medicine for oral administration, the rare side effect of Chinese medicine, but short time effect undesirable it is difficult to relief of symptoms.On market
Also have Chinese medicine class nasal drop, the peaceful nasal drop of such as BITONG, cure mainly nasal obstruction obstructed, effect is more single, and has pungent.
Therefore it provides a kind of good Chinese medicine nasal drop of rhinitis effect for the treatment of has important practical significance.
Content of the invention
In view of this, the present invention provides a kind of Chinese medicine composition, the nasal drop containing this Chinese medicine composition and its application.Should
Chinese medicine nasal drop has the effect of antibacterial, antiinflammatory, tranquillizing and allaying excitement, fatigue alleviating.
In order to realize foregoing invention purpose, present invention offer technical scheme below:
The invention provides a kind of compositionss, including Lignum Aquilariae Resinatum, Herba Xanthii and Herba Menthae.
In some specific embodiments of the present invention, described compositionss include the raw material of following mass parts:
2~4 parts of Lignum Aquilariae Resinatum
1~5 part of Herba Xanthii
1~4 part of Herba Menthae.
In some specific embodiments of the present invention, described compositionss include the raw material of following mass parts:
4 parts of Lignum Aquilariae Resinatum
5 parts of Herba Xanthii
4 parts of Herba Menthae.
Present invention also offers described compositionss prepare anti-inflammation, protection nasal mucosa, calm calm the nerves, fatigue alleviating
Medicine in application.
Present invention also offers application in the medicine of preparation treatment rhinitis for the described compositionss.
Present invention also offers the preparation method of described compositionss, comprise the steps:
Step 1: take the Herba Xanthii of formula ratio and Herba Menthae mix with water after reflux, extract, filter, collect filtrate reduced in volume, obtain
Obtain concentrated solution;
Step 2: supersound extraction after taking the Lignum Aquilariae Resinatum of formula ratio to be mixed with ethanol, is filtered, concentrating under reduced pressure removes ethanol, it is heavy to obtain
Fragrant extract;
Step 3: take the Lignum Aquilariae Resinatum extract mixing that the prepared concentrated solution of step 1 and step 2 are obtained.
In some specific embodiments of the present invention, in the preparation method step 1 of described compositionss, the addition of water is
Herba Xanthii and 5~10 times of Herba Menthae weight.
In some specific embodiments of the present invention, in the preparation method step 2 of described compositionss, the volume of ethanol is dense
Spend for 95%;Described ethanol weight is 1~10 times of Lignum Aquilariae Resinatum weight.
In some specific embodiments of the present invention, ultrasonic described in the preparation method step 2 of described compositionss carries
It is taken as 2~3 times, each time is 50min~70min, merging filtrate;Described decompression temperature is 40 DEG C~60 DEG C.
Present invention also offers a kind of Chinese medicine nasal drop, the group being obtained including described compositionss or described preparation method
Compound and pharmaceutically acceptable adjuvant.
The invention discloses a kind of Chinese medicine nasal drop, it is made up of the Chinese crude drug of following weight: 2~4 parts of Lignum Aquilariae Resinatum, Herba Xanthii 1~5
Part, 1~4 part of Herba Menthae.This Chinese medicine nasal drop not only has anti-inflammation, protection nasal mucosa effect, and have calm calm the nerves, slow
Effect of solution fatigue, few side effects.
Specific embodiment
The invention discloses a kind of Chinese medicine composition, the nasal drop containing this Chinese medicine composition and its application, this area skill
Art personnel can use for reference present disclosure, be suitably modified technological parameter and realize.Specifically, all similar replacements and
Change apparent to those skilled in the art, they are considered as including in the present invention.The method of the present invention and
Application is described by preferred embodiment, and related personnel substantially can be without departing from present invention, spirit and scope
Interior method described herein and application are modified or suitably change and combine, to realize and to apply the technology of the present invention.
The present invention provides a kind of technical scheme below: Chinese medicine nasal drop, is made up of the following raw material:
2~4 parts of Lignum Aquilariae Resinatum
1~5 part of Herba Xanthii
1~4 part of Herba Menthae.
Preferably, in described compositionss, the weight portion of Lignum Aquilariae Resinatum is 4 parts.
Preferably, in described compositionss, the weight portion of Herba Xanthii is 2 parts.
Preferably, in described compositionss, the weight portion of Herba Menthae is 2 parts.
Compared with prior art, the present invention is as the main functional component of Chinese medicine nasal drop, have in Lignum Aquilariae Resinatum Lignum Aquilariae Resinatum spiral alcohol,
The sesquiterpenoidss and 2- (2- phenethyl) chromone etc. such as baimuxinal, α-agarofuran, Lignum Aquilariae Resinatum refined sill indigo plant alcohol, baimuxinic acid
Chromone constituents, show that Lignum Aquilariae Resinatum has the multiple pharmacological effect such as antibacterial, antiinflammatory, antiallergic, tranquillizing and allaying excitement and fatigue alleviating.
There are the sesquiterpenes such as myrcene, β-eucalyptol, the sesquiterpene such as hidden Herba Xanthii lactone, Herba Xanthii lactone, Herba Xanthii Saponin in Herba Xanthii
Lactone constituents, show that Herba Xanthii has the multiple pharmacological effect such as antibacterial, antiinflammatory, antiviral, antiallergic.
Herba Menthae contains menthol, menthone, has wind-dispelling heat-dissipating, wards off dirty merit of removing toxic substances effect.
Using Lignum Aquilariae Resinatum as the main functional component of Chinese medicine nasal drop, the effect of antibacterial, antiinflammatory can be effectively acted as, with now
Some nasal drop compare, the present invention also have functions that calm calm the nerves, fatigue alleviating, have no side effect, be not likely to produce drug resistance,
Shorten the course of disease hence it is evident that improving the quality of living.
Present invention also offers the preparation method of above-mentioned Chinese medicine nasal drop, comprise the following steps:
1. the compositionss of each raw material blending, are taken by following proportionings:
1~5 part of Herba Xanthii
1~4 part of Herba Menthae
2., add water reflux, extract, in compositionss;Filter, by filtrate reduced in volume;
3., take Lignum Aquilariae Resinatum, add ethanol ultrasonic extraction;Filter, concentrating under reduced pressure removes ethanol;
4., 3. gained Lignum Aquilariae Resinatum extract will add 2. in gained concentrated solution, and mix, obtain final product Chinese medicine nasal drop.Preferably, walk
Rapid 2. middle 5~10 times of volumes for compositionss for the amount adding water;Described reflux, extract, be 2~3 times, each time be 40min~
70min, merging filtrate.
Preferably, 2. middle concentrating under reduced pressure is carried out step for 40~60 DEG C, and is concentrated into the 1/5~1/20 of original volume.
Preferably, 3. middle concentration of alcohol is 95% to step;Described supersound extraction is 2~3 times, and each time is 50min
~70min, merging filtrate;Described decompression is carried out for 40~60 DEG C.
The present invention only need to be carried out reflux, extract, reconcentration, add Lignum Aquilariae Resinatum extract by compositionss under solvent action
Obtain Chinese medicine nasal drop;The condition of whole manufacturing process is simple, processing ease, and used various crude drug all can be from medicine
Shop is commercially available, and its specification meets country or industry standard.
Raw materials used and examination in Chinese medicine composition, the nasal drop containing this Chinese medicine composition and its application that the present invention provides
Agent all can be buied by market.
With reference to embodiment, the present invention be expanded on further:
Embodiment 1
Weigh Herba Xanthii 100g, Herba Menthae 100g, add reflux, extract, 2 times, each 60min in 1000g water.Filter, merge filter
Liquid;By filtrate at 50 DEG C, it is evaporated to 50g.Weigh Lignum Aquilariae Resinatum 200g, add in the ethanol solution of 200ml 95%, ultrasonic
Extract 2 times, each 50min, filter, merging filtrate, by filtrate at 40 DEG C, be evaporated to no ethanol.Ethanol is removed under reduced pressure,
Gained Lignum Aquilariae Resinatum extract is added in the concentrated liquid of tradition Chinese medicine of 100g, mixes, as Chinese medicine nasal drop.
Embodiment 2
Weigh Lignum Aquilariae Resinatum 400g, add in the ethanol solution of 400ml 95%, supersound extraction 2 times, each 60min, filters, closes
And filtrate, ethanol is removed under reduced pressure, obtains Lignum Aquilariae Resinatum extract.Weigh Herba Xanthii 500g, Herba Menthae 400g, add reflux, extract, 2 in 9000g water
Secondary, each 70min.Filter, merging filtrate;By filtrate at 60 DEG C, it is evaporated to 1800g.Lignum Aquilariae Resinatum extract is added dense
In contracting liquid, mix, as Chinese medicine nasal drop.
Embodiment 3
Weigh Herba Xanthii 200g, Herba Menthae 160g, add reflux, extract, 3 times, each 50min in 2500g water.Filter, merge filter
Liquid;By filtrate at 50 DEG C, it is evaporated to 300g.Weigh Lignum Aquilariae Resinatum 160g, add in the ethanol solution of 200ml 95%, ultrasonic
Extract 3 times, each 60min, filter, merging filtrate, by filtrate at 60 DEG C, be evaporated to no ethanol.Ethanol is removed under reduced pressure,
Gained Lignum Aquilariae Resinatum extract is added in the concentrated liquid of tradition Chinese medicine of 300g, mixes, as Chinese medicine nasal drop.
The antibacterial experiment of test example 4 Chinese medicine nasal drop of the present invention
Chinese medicine nasal drop prepared by Example 1~3 respectively, nasal drop is diluted to 50mg/ml (to be provided for the present invention
Nasal drop solute mass concentration).Measure the anti-Staphylococcus aureus of concentrated solution using filter paper agar diffusion method
(staphylococcus aureus) and methicillin-resistant staphylococcus Fructus Vitis viniferae ball (methicillin-resistant
Staphylococcus aureus, mrsa) activity.S.aureus and mrsa adopts na culture medium culturing.By s.aureus and
Mrsa is respectively prepared certain density bacteria suspension (105~107Cfu/ml), it is spread evenly across for examination aseptic flat board with cotton swab,
Make flat board containing bacterium.Then separately sampled product solution (the Chinese medicine nasal drop prepared by embodiment 1~3 and positive control) 50 μ l
Deca (φ=6mm) on sterilizing filter paper piece, after solvent volatilizes, filter paper is affixed on flat board containing bacterium respectively, often processes and repeats
3 times.Then 37 DEG C of constant temperature culture.Observed result after 24h, measures and records antibacterial circle diameter.With naphcon nasal drop
As positive control.
Result of the test table 1 shows, the present invention is respectively provided with significantly compared with positive controls (naphcon nasal drop)
Difference (p < 0.05), the extract of the inventive method preparation shows obvious inhibitory action to two kinds of human body pathogen.
The antibacterial circle diameter (mm, n=3) to two kinds of pathogen for table 1 present composition
Note: significant difference (p < 0.05);The a diameter of 6mm of filter paper dick.
Naphcon nasal drop does positive control.
The antiinflammatory experiment of test example 5 present composition
Take Kunming mouse 100, be randomly divided into 6 groups, every group 20, male and female half and half.Negative control group gives equal-volume
Distilled water, positive controls by specification gives naphcon nasal drop, and other 3 groups give prepared by embodiment 1~3
Concentrated solution, each dosage be 10ml concentrated solution, one time a day, for three days on end.1h after last dose, drips to mouse right ear with two
Only, left ear compares toluene 0.05ml/.Put to death animal after 15 minutes, with the card punch of diameter 6cm, ears taken with position,
Weigh on sensibility reciprocal is for the analytical precision balances of 1mg, each group swelling is calculated with the difference of left and right ear piece weight, and between comparable group
Difference.
As shown in table 2, the present invention is respectively provided with significance difference compared with positive controls (naphcon nasal drop) to result
Different (p < 0.05), the present composition can substantially resist the mice auricle swelling caused by dimethylbenzene, have stronger antiinflammatory action.
The impact to mice auricle swelling for table 2 present composition
Group | Number of animals | Swelling (%) |
Negative control group | 20 | 0.59±0.15? |
Embodiment 1 | 20 | 0.17±0.10? |
Embodiment 2 | 20 | 0.16±0.11? |
Embodiment 3 | 20 | 0.14±0.08? |
Naphcon nasal drop | 20 | 0.13±0.10? |
?p<0.05
Embodiment 6 crowd tries out
100 triers are allowed to use each 10 times of the Chinese medicine nasal drop of nasal drop and embodiment 2 preparation on market, contrast is beaten
The situation of dividing is as shown in table 3:
Table 3 compound agilawood hair cream crowd tries out marking
Test group (present invention) in table 3 is respectively provided with significant difference (p < 0.05) compared with matched group (commercially available), and this is described
Invention Chinese medicine nasal drop can effectively suppress bacterial viruses growth, promote nasal cavity tissue reparation, protection nasal mucosa effect,
Non-stimulated, and compared with the medicine on market, the present invention also have functions that calm calm the nerves, fatigue alleviating, have no side effect, contracting
The short course of disease is hence it is evident that improve the quality of living.
Example 1, the Chinese medicine nasal drop of embodiment 3 preparation carry out above-mentioned experiment, experimental result and embodiment 2 preparation
The experimental result of Chinese medicine nasal drop is close, no significant difference (p > 0.05).
The above is only the preferred embodiment of the present invention it is noted that ordinary skill people for the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (10)
1. a kind of compositionss are it is characterised in that include Lignum Aquilariae Resinatum, Herba Xanthii and Herba Menthae.
2. compositionss according to claim 1 are it is characterised in that include the raw material of following mass parts:
2~4 parts of Lignum Aquilariae Resinatum
1~5 part of Herba Xanthii
1~4 part of Herba Menthae.
3. compositionss according to claim 1 and 2 are it is characterised in that include the raw material of following mass parts:
4 parts of Lignum Aquilariae Resinatum
5 parts of Herba Xanthii
4 parts of Herba Menthae.
4. the compositionss according to any one of claims 1 to 3 are being prepared anti-inflammation, protection nasal mucosa, are being calmed and calm the nerves, delay
Application in the medicine of solution fatigue.
5. application in the medicine of preparation treatment rhinitis for the compositionss according to any one of claims 1 to 3.
6. the preparation method of the compositionss according to any one of claims 1 to 3 is it is characterised in that comprise the steps:
Step 1: take the Herba Xanthii of formula ratio and Herba Menthae mix with water after reflux, extract, filter, collect filtrate reduced in volume, obtain dense
Contracting liquid;
Step 2: supersound extraction after taking the Lignum Aquilariae Resinatum of formula ratio to be mixed with ethanol, is filtered, concentrating under reduced pressure removes ethanol, obtains Lignum Aquilariae Resinatum and carry
Take thing;
Step 3: take the Lignum Aquilariae Resinatum extract mixing that the prepared concentrated solution of step 1 and step 2 are obtained.
7. preparation method according to claim 6 is it is characterised in that the addition of water is Herba Xanthii and Herba Menthae is heavy in step 1
5~10 times of amount.
8. preparation method according to claim 6 it is characterised in that in step 2 ethanol volumetric concentration be 95%;Described
Ethanol weight be 1~10 times of Lignum Aquilariae Resinatum weight.
9. preparation method according to claim 6 is it is characterised in that the supersound extraction described in step 2 is 2~3 times, often
The secondary time is 50min~70min, merging filtrate;Described decompression temperature is 40 DEG C~60 DEG C.
10. a kind of Chinese medicine nasal drop is it is characterised in that include compositionss as described in any one of claims 1 to 3 or as right
Require the prepared compositionss of the preparation method described in 6~9 any one and pharmaceutically acceptable adjuvant.
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CN201610893618.4A CN106334034A (en) | 2016-10-13 | 2016-10-13 | Traditional Chinese medicine compositon, nose drop containing same and application thereof |
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CN201610893618.4A CN106334034A (en) | 2016-10-13 | 2016-10-13 | Traditional Chinese medicine compositon, nose drop containing same and application thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107050198A (en) * | 2017-03-17 | 2017-08-18 | 上海中医药大学 | A kind of health care stacte and preparation method for winter health |
CN111407858A (en) * | 2020-03-25 | 2020-07-14 | 东方花梨之乡开发有限公司 | Chinese eaglewood mixture for sterilizing, disinfecting, diminishing inflammation and dispelling wind-damp and preparation method thereof |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1413675A (en) * | 2002-08-28 | 2003-04-30 | 李家文 | Hollow multifunction incense and its preparation method and using method |
CN101112483A (en) * | 2007-08-23 | 2008-01-30 | 郭锡珍 | Medicine for treating rhinitis and method for preparing the same |
CN104288226A (en) * | 2014-10-20 | 2015-01-21 | 中山百鸥医药科技有限公司 | Compound nasal drops |
CN104474142A (en) * | 2014-12-17 | 2015-04-01 | 董长海 | Traditional Chinese medicine composition for treating rhinitis |
CN105106814A (en) * | 2015-08-21 | 2015-12-02 | 刘高志 | Traditional Chinese medicine combination for treating viral rhinitis |
CN105193892A (en) * | 2014-05-31 | 2015-12-30 | 张小粉 | Xanthium sibiricum naristillae |
-
2016
- 2016-10-13 CN CN201610893618.4A patent/CN106334034A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1413675A (en) * | 2002-08-28 | 2003-04-30 | 李家文 | Hollow multifunction incense and its preparation method and using method |
CN101112483A (en) * | 2007-08-23 | 2008-01-30 | 郭锡珍 | Medicine for treating rhinitis and method for preparing the same |
CN105193892A (en) * | 2014-05-31 | 2015-12-30 | 张小粉 | Xanthium sibiricum naristillae |
CN104288226A (en) * | 2014-10-20 | 2015-01-21 | 中山百鸥医药科技有限公司 | Compound nasal drops |
CN104474142A (en) * | 2014-12-17 | 2015-04-01 | 董长海 | Traditional Chinese medicine composition for treating rhinitis |
CN105106814A (en) * | 2015-08-21 | 2015-12-02 | 刘高志 | Traditional Chinese medicine combination for treating viral rhinitis |
Non-Patent Citations (3)
Title |
---|
年思新: "苍耳子滴鼻剂治疗鼻炎47例报告", 《江西中医药》 * |
李西林 等: "《名贵中药材鉴别》", 31 October 2013, 上海科学技术出版社 * |
陈堃 等: "《陈卫川回医临证实录方》", 31 August 2015, 阳光出版社 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107050198A (en) * | 2017-03-17 | 2017-08-18 | 上海中医药大学 | A kind of health care stacte and preparation method for winter health |
CN107050198B (en) * | 2017-03-17 | 2020-06-26 | 上海中医药大学 | Health-care incense for preserving health in winter and preparation method thereof |
CN111407858A (en) * | 2020-03-25 | 2020-07-14 | 东方花梨之乡开发有限公司 | Chinese eaglewood mixture for sterilizing, disinfecting, diminishing inflammation and dispelling wind-damp and preparation method thereof |
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Application publication date: 20170118 |