CN101069098B - 基于颗粒的结合测定 - Google Patents

基于颗粒的结合测定 Download PDF

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Publication number
CN101069098B
CN101069098B CN200580041554.5A CN200580041554A CN101069098B CN 101069098 B CN101069098 B CN 101069098B CN 200580041554 A CN200580041554 A CN 200580041554A CN 101069098 B CN101069098 B CN 101069098B
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China
Prior art keywords
binding
particles
analyte
porous surface
binding component
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Expired - Fee Related
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CN200580041554.5A
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English (en)
Chinese (zh)
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CN101069098A (zh
Inventor
胡阿尼·卢奥托拉
汉努·尼库拉
米拉·穆尔托弗瑞
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Aidian Oy
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Orion Diagnostica Oy
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/971—Capture of complex after antigen-antibody reaction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN200580041554.5A 2004-12-03 2005-11-23 基于颗粒的结合测定 Expired - Fee Related CN101069098B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0426592.2 2004-12-03
GB0426592A GB2420850A (en) 2004-12-03 2004-12-03 Particle based binding assay
PCT/EP2005/012523 WO2006058645A1 (en) 2004-12-03 2005-11-23 Particle based binding assay

Publications (2)

Publication Number Publication Date
CN101069098A CN101069098A (zh) 2007-11-07
CN101069098B true CN101069098B (zh) 2013-03-27

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Family Applications (1)

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CN200580041554.5A Expired - Fee Related CN101069098B (zh) 2004-12-03 2005-11-23 基于颗粒的结合测定

Country Status (11)

Country Link
US (1) US7709212B2 (enExample)
EP (1) EP1825273B1 (enExample)
JP (2) JP4482035B2 (enExample)
CN (1) CN101069098B (enExample)
AU (1) AU2005311530B2 (enExample)
CA (1) CA2589071C (enExample)
DK (1) DK1825273T3 (enExample)
ES (1) ES2536741T3 (enExample)
GB (1) GB2420850A (enExample)
NO (1) NO20073311L (enExample)
WO (1) WO2006058645A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4964161B2 (ja) * 2008-02-07 2012-06-27 株式会社日立ハイテクノロジーズ 磁性粒子を用いた分析方法
WO2012030870A1 (en) * 2010-08-30 2012-03-08 Mks Technology (D/B/A Snowy Range Instruments) Spectroscopic assays and tagging
EP2694965B1 (en) * 2011-04-05 2017-01-18 Purdue Research Foundation Micro-fluidic system using micro-apertures for high throughput detection of entities
US9889445B2 (en) 2013-10-22 2018-02-13 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
EP3783094B1 (en) * 2013-10-22 2023-10-11 Berkeley Lights, Inc. Micro-fluidic devices for assaying biological activity
SG11201602340TA (en) * 2013-10-22 2016-05-30 Berkeley Lights Inc Exporting a selected group of micro-objects from a micro-fluidic device
DK3060912T3 (da) * 2013-10-22 2020-09-28 Berkeley Lights Inc Fremgangsmåde og mikrofluidanordning til analyse af biologisk aktivitet
CN104459127B (zh) * 2013-12-16 2018-03-23 顾晋元 生物载体及其在检测中的应用
BR112017002136A2 (pt) 2014-08-03 2017-11-21 Pogotec Inc ?sistema de dispositivo eletrônico?
CN111812336A (zh) * 2020-08-10 2020-10-23 苏州康和顺医疗技术有限公司 用于检测冠状病毒抗体的检测试剂盒及其制备方法
CN117554606A (zh) * 2023-10-13 2024-02-13 北京大学 多孔滤膜辅助的磁珠法免疫检测方法

Citations (3)

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US5236836A (en) * 1989-04-25 1993-08-17 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US6096563A (en) * 1996-03-29 2000-08-01 Strategic Diagnostics Inc. Dual particle immunoassay method and kit
US6632603B1 (en) * 1996-02-22 2003-10-14 Dexall Biomedical Labs Inc Non-captive substrate liquid phase immunoassay

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US4054646A (en) 1973-07-30 1977-10-18 General Electric Method and apparatus for detection of antibodies and antigens
SE407115B (sv) 1975-10-06 1979-03-12 Kabi Ab Forfarande och metelektroder for studium av enzymatiska och andra biokemiska reaktioner
US4238757A (en) 1976-03-19 1980-12-09 General Electric Company Field effect transistor for detection of biological reactions
US4219335A (en) 1978-09-18 1980-08-26 E. I. Du Pont De Nemours And Company Immunochemical testing using tagged reagents
GB2045431B (en) 1979-02-26 1983-04-20 Technicon Instr Immunoassay utilising two particulate reagents
US4233144A (en) 1979-04-16 1980-11-11 Technicon Instruments Corporation Electrode for voltammetric immunoassay
US4287300A (en) 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
GB2123146B (en) 1982-06-28 1985-09-25 Abbott Lab Dual parameter flow immunoassays
US4632901A (en) 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
TW203120B (enExample) 1985-10-04 1993-04-01 Abbott Lab
US5501949A (en) 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
US5236826A (en) * 1985-12-10 1993-08-17 Murex Corporation Immunoassay for the detection or quantitation of an analyte
US4916056A (en) 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
US5137827A (en) 1986-03-25 1992-08-11 Midwest Research Technologies, Inc. Diagnostic element for electrical detection of a binding reaction
CA1288690C (en) 1986-07-14 1991-09-10 Virginia Petro-Roy Apparatus and process for immunoassays
US4853335A (en) 1987-09-28 1989-08-01 Olsen Duane A Colloidal gold particle concentration immunoassay
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
NO164622C (no) * 1988-05-11 1990-10-24 Tore Lindmo Binaer immunometrisk partikkelbasert metode for maaling av spesifikke serum-antigener ved hjelp av vaeskestroemsmikrofotometri og et ferdigpreparert maaloppsett derav.
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
WO1991013353A1 (en) 1990-02-22 1991-09-05 The Royal Institution For The Advancement Of Learning (Mcgill University) A solid-phase interferometric immunoassay system
EP0556202B1 (en) 1990-09-26 1997-05-14 Akers Laboratories, Inc. Improved ligand assay
JP3142873B2 (ja) 1993-02-01 2001-03-07 ラブシステムズ オユ 磁性粒子の特異的結合による検定の方法および装置
CA2318779C (en) 1998-01-22 2009-08-25 Luminex Corporation Microparticles with multiple fluorescent signals
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
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US7361313B2 (en) * 2003-02-18 2008-04-22 Intel Corporation Methods for uniform metal impregnation into a nanoporous material
US20050214737A1 (en) * 2004-03-26 2005-09-29 Dejneka Matthew J Transparent filtered capillaries

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5236836A (en) * 1989-04-25 1993-08-17 Igen, Inc. Autoantibodies which enhance the rate of a chemical reaction
US6632603B1 (en) * 1996-02-22 2003-10-14 Dexall Biomedical Labs Inc Non-captive substrate liquid phase immunoassay
US6096563A (en) * 1996-03-29 2000-08-01 Strategic Diagnostics Inc. Dual particle immunoassay method and kit

Also Published As

Publication number Publication date
AU2005311530B2 (en) 2011-12-15
AU2005311530A1 (en) 2006-06-08
JP2008522170A (ja) 2008-06-26
NO20073311L (no) 2007-09-03
ES2536741T3 (es) 2015-05-28
CA2589071A1 (en) 2006-06-08
GB2420850A (en) 2006-06-07
JP2010060567A (ja) 2010-03-18
EP1825273A1 (en) 2007-08-29
DK1825273T3 (en) 2015-05-26
WO2006058645A1 (en) 2006-06-08
GB0426592D0 (en) 2005-01-05
CN101069098A (zh) 2007-11-07
US20080160537A1 (en) 2008-07-03
EP1825273B1 (en) 2015-04-15
JP4482035B2 (ja) 2010-06-16
US7709212B2 (en) 2010-05-04
CA2589071C (en) 2014-05-13

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Granted publication date: 20130327