CN101056617A - 用于动物的在原位形成的植入物 - Google Patents
用于动物的在原位形成的植入物 Download PDFInfo
- Publication number
- CN101056617A CN101056617A CNA2005800386792A CN200580038679A CN101056617A CN 101056617 A CN101056617 A CN 101056617A CN A2005800386792 A CNA2005800386792 A CN A2005800386792A CN 200580038679 A CN200580038679 A CN 200580038679A CN 101056617 A CN101056617 A CN 101056617A
- Authority
- CN
- China
- Prior art keywords
- compositions
- solvent
- thermoplastic polymer
- adjuvant
- bioactivator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
制剂 | 生物活性成分1 | 热塑性聚合物2 | 溶剂3 | 佐剂:乙醇 | 佐剂:甘油缩甲醛 | 佐剂:甘油 |
A | 200 | 200 | 799 | - | - | - |
B | 200 | 150 | 845 | - | - | - |
C | 200 | 200 | 653 | 100 | - | - |
D | 200 | 150 | 698 | 100 | - | - |
E | 200 | 200 | 702 | - | 100 | - |
F | 200 | 200 | 705 | - | - | 100 |
制剂 | 犬编号 | 最大值(注射后天数) | 50天 | 100天 | 200天 | 400天 |
A | 1 | 89.2(2) | 8.2 | 7.6 | 3.5 | 4.1 |
A | 2 | 87.6(2) | 44.7 | 32.1 | 5.7 | 5.9 |
B | 3 | 92.7(2) | 27.4 | 26.2 | 26.7 | 5.6 |
B | 4 | 117.2(13) | 21 | 15.3 | 7.4 | 8.9 |
C | 5 | 44.2(3) | 2.4 | 3.3 | 9.8 | 14 |
C | 6 | 47.5(4) | 5.4 | 4.2 | 2.6 | 1.9 |
D | 7 | 61.2(1) | 7.1 | 3.8 | 2.1 | - |
D | 8 | 48.9(2) | 10.1 | 4.8 | 3.1 | - |
E | 9 | 35.6(2) | 4.9 | 2.8 | 1.9 | 3.0 |
E | 10 | 37.4(6) | 11.5 | 7.4 | 3.7 | 3.4 |
F | 11 | 35.0(2) | 3.3 | 2.6 | 1.0 | 1.8 |
F | 12 | 40.6(2) | 2.2 | 2.5 | 2.0 | 2.4 |
Claims (20)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04029498 | 2004-12-14 | ||
EP04029498.5 | 2004-12-14 | ||
PCT/EP2005/013377 WO2006063794A1 (en) | 2004-12-14 | 2005-12-13 | In-situ forming implant for animals |
Publications (2)
Publication Number | Publication Date |
---|---|
CN101056617A true CN101056617A (zh) | 2007-10-17 |
CN101056617B CN101056617B (zh) | 2012-07-11 |
Family
ID=34927750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005800386792A Expired - Fee Related CN101056617B (zh) | 2004-12-14 | 2005-12-13 | 用于动物的在原位形成的植入物 |
Country Status (16)
Country | Link |
---|---|
JP (1) | JP5372378B2 (zh) |
KR (1) | KR101304160B1 (zh) |
CN (1) | CN101056617B (zh) |
AR (1) | AR052155A1 (zh) |
AT (1) | ATE389386T1 (zh) |
AU (1) | AU2005315823B2 (zh) |
BR (1) | BRPI0519022A2 (zh) |
CA (1) | CA2585779C (zh) |
DE (1) | DE602005005522T2 (zh) |
ES (1) | ES2301084T3 (zh) |
MX (1) | MX2007007099A (zh) |
NZ (1) | NZ554904A (zh) |
RU (1) | RU2394558C2 (zh) |
TW (1) | TWI369218B (zh) |
WO (1) | WO2006063794A1 (zh) |
ZA (1) | ZA200703506B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8300883B2 (en) | 2007-11-29 | 2012-10-30 | Tencent Technology (Shenzhen) Company Ltd. | Sketch generating system and method for generating sketch based on image |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
BRPI0811319A2 (pt) | 2007-05-25 | 2015-02-10 | Tolmar Therapeutics Inc | Composição fluida, método de formação de uma composição fluida, implante biodegrádavel formado in situ, método de formação de um implante biodegradável in situ, kit, implante e método de trataento |
US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US9877973B2 (en) | 2008-05-12 | 2018-01-30 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
US10588855B2 (en) | 2008-05-12 | 2020-03-17 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
JP6543431B2 (ja) * | 2013-10-10 | 2019-07-10 | ユニバーシティー オブ ユタ リサーチ ファウンデーションUniversity of Utah Research Foundation | 眼内薬物送達デバイスおよび付随する方法 |
EP3609470B1 (en) | 2017-04-13 | 2023-11-22 | Ceva Santé Animale | Implant for treating parasites infestations |
CN112336682B (zh) * | 2020-09-28 | 2022-07-08 | 浙江大学 | 具有缓控释药物作用的可注射复合载体与组合物及制备方法 |
WO2024003291A1 (en) | 2022-06-30 | 2024-01-04 | Virbac | Deslorelin use in chemical castration of a non-human mammal related to pk/pd interaction |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US5324519A (en) * | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
ES2158611T3 (es) * | 1996-12-20 | 2001-09-01 | Alza Corp | Composicion en gel inyectable con efecto retard y procedimiento para la preparacion de dicha composicion. |
ME00867B (me) * | 1998-03-19 | 2008-08-07 | Merck Sharp & Dohme | Tečne polimerne smeše za kontrolisano oslobađanje bioaktivnih supstanci |
US7128927B1 (en) * | 1998-04-14 | 2006-10-31 | Qlt Usa, Inc. | Emulsions for in-situ delivery systems |
JP4317606B2 (ja) * | 1998-09-18 | 2009-08-19 | サンスター株式会社 | 固体粒子形成用組成物 |
RU2355385C2 (ru) * | 2002-11-06 | 2009-05-20 | Алза Корпорейшн | Композиции пролонгированного действия с контролируемым высвобождением |
JP2007525429A (ja) * | 2003-03-11 | 2007-09-06 | キューエルティー ユーエスエー,インコーポレイテッド. | 細胞スケジュール依存性抗癌剤のための処方 |
-
2005
- 2005-12-12 TW TW094143807A patent/TWI369218B/zh not_active IP Right Cessation
- 2005-12-12 AR ARP050105195A patent/AR052155A1/es unknown
- 2005-12-13 DE DE602005005522T patent/DE602005005522T2/de active Active
- 2005-12-13 CN CN2005800386792A patent/CN101056617B/zh not_active Expired - Fee Related
- 2005-12-13 WO PCT/EP2005/013377 patent/WO2006063794A1/en active Application Filing
- 2005-12-13 RU RU2007126759/15A patent/RU2394558C2/ru not_active IP Right Cessation
- 2005-12-13 JP JP2007545931A patent/JP5372378B2/ja not_active Expired - Fee Related
- 2005-12-13 CA CA2585779A patent/CA2585779C/en not_active Expired - Fee Related
- 2005-12-13 BR BRPI0519022-3A patent/BRPI0519022A2/pt not_active IP Right Cessation
- 2005-12-13 ES ES05815330T patent/ES2301084T3/es active Active
- 2005-12-13 MX MX2007007099A patent/MX2007007099A/es active IP Right Grant
- 2005-12-13 KR KR1020077013264A patent/KR101304160B1/ko not_active IP Right Cessation
- 2005-12-13 AT AT05815330T patent/ATE389386T1/de not_active IP Right Cessation
- 2005-12-13 AU AU2005315823A patent/AU2005315823B2/en not_active Ceased
- 2005-12-13 NZ NZ554904A patent/NZ554904A/en not_active IP Right Cessation
-
2007
- 2007-05-02 ZA ZA200703506A patent/ZA200703506B/xx unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8300883B2 (en) | 2007-11-29 | 2012-10-30 | Tencent Technology (Shenzhen) Company Ltd. | Sketch generating system and method for generating sketch based on image |
Also Published As
Publication number | Publication date |
---|---|
ATE389386T1 (de) | 2008-04-15 |
CA2585779C (en) | 2014-01-28 |
ES2301084T3 (es) | 2008-06-16 |
AR052155A1 (es) | 2007-03-07 |
KR101304160B1 (ko) | 2013-09-04 |
RU2007126759A (ru) | 2009-01-27 |
MX2007007099A (es) | 2007-06-22 |
AU2005315823A1 (en) | 2006-06-22 |
RU2394558C2 (ru) | 2010-07-20 |
JP2008523131A (ja) | 2008-07-03 |
JP5372378B2 (ja) | 2013-12-18 |
CN101056617B (zh) | 2012-07-11 |
NZ554904A (en) | 2009-11-27 |
DE602005005522T2 (de) | 2009-04-16 |
WO2006063794A1 (en) | 2006-06-22 |
DE602005005522D1 (de) | 2008-04-30 |
BRPI0519022A2 (pt) | 2008-12-23 |
CA2585779A1 (en) | 2006-06-22 |
AU2005315823B2 (en) | 2009-06-04 |
TW200635616A (en) | 2006-10-16 |
KR20070092964A (ko) | 2007-09-14 |
TWI369218B (en) | 2012-08-01 |
ZA200703506B (en) | 2008-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: NOVARTIS CO., LTD. Free format text: FORMER NAME: NOVARTIS AG |
|
CP01 | Change in the name or title of a patent holder |
Address after: Basel Patentee after: Novartis Ag Address before: Basel Patentee before: Novartis AG |
|
ASS | Succession or assignment of patent right |
Owner name: SWISS NOVARTIS ANIMAL HEALTH CO., LTD. Free format text: FORMER OWNER: NOVARTIS CO., LTD. Effective date: 20150423 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20150423 Address after: Basel Patentee after: Animal health company limited of Novartis of Switzerland Address before: Basel Patentee before: Novartis Ag |
|
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120711 Termination date: 20151213 |
|
EXPY | Termination of patent right or utility model |