CN101044242B - 肿瘤特异性抗体 - Google Patents

肿瘤特异性抗体 Download PDF

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Publication number
CN101044242B
CN101044242B CN2005800272005A CN200580027200A CN101044242B CN 101044242 B CN101044242 B CN 101044242B CN 2005800272005 A CN2005800272005 A CN 2005800272005A CN 200580027200 A CN200580027200 A CN 200580027200A CN 101044242 B CN101044242 B CN 101044242B
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antibody
cancer
cells
protein
seq
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Expired - Fee Related
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CN101044242A (zh
Inventor
尼古拉斯·罗纳德·格罗沃
格伦·克里斯多佛·麦克唐纳
乔伊斯林·恩特韦斯特尔
吉恩尼克·西兹尔尤
丹尼斯·乔治沙·鲍斯克
弗兰西娜·C.·查海尔
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Viventia Bio Inc
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Viventia Biotech Inc
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2884—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD44
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • C07K2319/00—Fusion polypeptide
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CN2005800272005A 2004-06-10 2005-06-10 肿瘤特异性抗体 Expired - Fee Related CN101044242B (zh)

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US57829104P 2004-06-10 2004-06-10
US60/578,291 2004-06-10
PCT/CA2005/000899 WO2005121341A1 (en) 2004-06-10 2005-06-10 Tumor specific antibody

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CN101044242A CN101044242A (zh) 2007-09-26
CN101044242B true CN101044242B (zh) 2013-10-30

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EP (2) EP2927322A1 (cg-RX-API-DMAC7.html)
JP (2) JP5026268B2 (cg-RX-API-DMAC7.html)
CN (1) CN101044242B (cg-RX-API-DMAC7.html)
AU (1) AU2005252275B2 (cg-RX-API-DMAC7.html)
CA (1) CA2569788C (cg-RX-API-DMAC7.html)
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EP2382990B1 (en) 2003-04-30 2014-09-17 Universität Zürich Methods for treating cancer using an immunotoxin
JP5025460B2 (ja) 2004-03-19 2012-09-12 メルク パテント ゲーエムベーハー 修飾ブーゲニンタンパク質、サイトトキシン、ならびにそれらの方法および使用
CA2633138A1 (en) * 2005-12-23 2007-06-28 Viventia Biotech Inc. Methods for generating and screening fusion protein libraries and uses thereof
US8263744B2 (en) 2007-04-19 2012-09-11 Viventia Biotechnologies Inc. Binding proteins that bind to EpCAM linked to an effector molecule
GB0718045D0 (en) 2007-09-14 2007-10-24 Peptcell Ltd Pharmaceutical compound
US8318472B2 (en) 2007-09-27 2012-11-27 Viventia Biotechnologies Inc. Optimized nucleic acid sequences for the expression of VB4-845
CA2709380A1 (en) * 2007-12-21 2009-07-09 University Of Rochester Cd24 as a brain tumor stem cell marker and a diagnostic and therapeutic target in primary neural and glial tumors of the brain
US20100008978A1 (en) * 2008-05-09 2010-01-14 The Regents Of The University Of California Nanoparticles effective for internalization into cells
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