CN101028375B - Oral externally-applied Chinese medicinal composition for treating leucoderma - Google Patents

Oral externally-applied Chinese medicinal composition for treating leucoderma Download PDF

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CN101028375B
CN101028375B CN2007100142233A CN200710014223A CN101028375B CN 101028375 B CN101028375 B CN 101028375B CN 2007100142233 A CN2007100142233 A CN 2007100142233A CN 200710014223 A CN200710014223 A CN 200710014223A CN 101028375 B CN101028375 B CN 101028375B
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fructus
radix
skin
radix angelicae
vitiligo
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CN101028375A (en
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李春玲
任晓
高圣龙
孙立新
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Li Chunling
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Abstract

A Chinese medicine for treating leukoderma by both exterior and interior applications is prepared from 19 Chinese-medicinal materials including Chinese angelica root, Chuan-xiong rhizome, fleece flower root, black sesame, etc through immersing them in liquor for 7 days.

Description

The leukodermic Chinese medicine composition of a kind of oral administration and externally used for curing
Technical field
The present invention relates to the leukodermic Chinese medicine composition of a kind of oral administration and externally used for curing, belong to the field of Chinese medicines.
Background technology
Vitiligo is a kind of common skin disease, and it is that a kind of acquired skin pigment takes off the property lost disease, and sickness rate is 0.5%-2%.Primary disease is known from ancient times, and " leucoderma " speech sees 610 years Christian eras Sui's Chao Yuanfang (550-630 A.D.)s and shows " all source of disease marquis's opinions " on motherland doctor nationality, and this book is stated vitiligo and is " it is different with yellowish pink that face and neck body skin yellowish pink bleach, also sufferings not, the leucoderma of meaning ".Primary disease is common in the world, all can suffer from each race, and this disease is local depigmentation, and the influence beauty treatment is easily examined and refractory.
The vitiligo pathogenic factor mainly is because human body heat in blood or body heat, outer wind-engaging, is subjected to humidity, and rheumatism is invaded skin, causes local disorder of QI and blood, the not flourish skin of blockage of main and collateral channels, blood, and the stagnation of QI, chosure of pores, thus form vitiligo; Wound also causes vitiligo easily; So dizzy nevus can reduce leukodermic a kind of owing to pathology is identical.This onset of disease speckle that is white in color spreads into patch, skin lesion appearing without definite location for a long time.It is attractive in appearance to influence human body.The often out in the cold and mistaken diagnosis of initial stage vitiligo.The external symptom of vitiligo shows as generally speaking: the affected part is white in color, and is more obvious with normal colour of skin boundary, do not protrude in skin, chosure of pores, illing skin is more smooth, no squama, no sufferings, be symmetrically distributed mostly, individual patient bleaches with hair, the premorbid non-evident sympton.Said pathogenic factor is an endogenous cause of ill above us, and the exopathogenic factor that causes vitiligo morbidity much and very complicated according to clinical observation, following situation occurred mostly to some extent before patients with vitiligo is ill: trick heating in summer, and serious when especially sleeping; Hyperhidrosis; It is bad to sleep; Work, living or studying pressure is big; Experience great misfortune or tribulation; The moist environment of long-term contact; Under the sun, be exposed to the sun for a long time; Wind-engaging behind the antiperspirant; The diet collocation is unreasonable; Be subjected to wound; Peppery irritable food of surfeit raw meat or the like.Present various pollution also is a factor that causes patients with vitiligo to increase year by year.This disease does not infect, and also less according to clinical observation heredity probability, most of patient is the gained day after tomorrow.
Leucoderma disease is mainly in the abundant position of sweat glands such as human body face, cervical region, extremity, waist and belly and back.Spring and summer, development was very fast.Disease sites is superficial generally speaking.But have discrete patient's disease sites that scratchiness is arranged, this is indicating that there is the trend of diffusion, development in this affected part.Leucoderma disease exists incubation period, and the state of an illness does not temporarily develop, and does not just mean that from now on and no longer developed.In case patient flu, unhappy, be subjected to factor affecting such as external environment stimulation cause the function disorder, when body immunity descends, the state of an illness also can continue development.During the initial stage and pay no attention to, there is fluke mind in vitiligo in many patients, have often missed the best period of treatment, wait and develop into area when quite big, and curing just needs long period of time.Especially this sick skin lesion appearing without definite location is exposed to outer position if develop into, and can have influence on patient's emotion and work from now on life, if be further development of the leukodermic words of general large tracts of land, can cause perspire not smooth, the skin cell metabolism disorder might be brought out other disease.
The therapy for vitiligo method has at present: Chinese-western medicine preparation, Western medicine injection of hormone, ultraviolet radiation, surgery skin grafting, instrument treatment and enhance immunity therapy etc.Above therapeutic scheme all belongs to the refractory basis of taking stopgap measures, and easily recurrence causes bad mental pressure and serious financial burden to extensive patients, and allows the patient miss best occasion for the treatment.
Summary of the invention
The present invention has overcome the deficiencies in the prior art, and provides a kind of oral administration and externally used for curing leukodermic Chinese medicine composition, all selects natural Chinese medicinal herb for use, fundamentally treats vitiligo.
Technical scheme of the present invention is: the leukodermic Chinese medicine composition of this kind oral administration and externally used for curing, it is characterized in that, make raw materials of effective components and be: Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Fructus Ligustri Lucidi 15, Fructus Psoraleae 15, Radix Polygoni Multiflori 30, Fructus Atriplicis Sibiricae 30, Semen Sesami Nigrum 30, Radix Saposhnikoviae 10, the Rhizoma Atractylodis Macrocephalae 10, Fructus Lycii 10, Flos Carthami 10, Agkistrodon 3, Radix Clematidis 12, Herba Lysimachiae 20, Fructus Mori 6, Fructus Psoraleae 30, Semen Cuscutae 10, the Radix Angelicae Dahuricae 10 and Borneolum Syntheticum 2 by following weight portion.
Preparation and instructions of taking: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Ligustri Lucidi, Fructus Psoraleae, Radix Polygoni Multiflori, Fructus Atriplicis Sibiricae, Semen Sesami Nigrum, Radix Saposhnikoviae, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii, Flos Carthami, Agkistrodon, Radix Clematidis, Herba Lysimachiae and Fructus Mori are put into marmite, add 500 milliliters in water, be decocted in water for oral dose, potion on the one, potion is taken at twice.With the back external of 60 ° of soaking in Chinese liquor one week, every day is twice outer skin lesion position of wiping sooner or later with Fructus Psoraleae, Semen Cuscutae, the Radix Angelicae Dahuricae and Borneolum Syntheticum, and suitably friction increases sunshine, obvious erythema vesicle degree of being to occur.Ten days is a course of treatment.
Pharmacological action:
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.
Radix Polygoni Multiflori: tonifying liver, kidney tonifying nourishes blood, and dispels the wind.The treating the liver kidney yin is lost, and sending out must be early white, blood deficiency dizziness, waist knee joint weakness etc.
Fructus Psoraleae: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.Be used for impotence and seminal emission, chills and pain of the waist and kness, suffer from a deficiency of the kidney and do to breathe heavily, have loose bowels just before dawn; Vitiligo, alopecia areata.
Semen Sesami Nigrum: invigorating the liver and kidney, benefiting essence-blood, intestine moistening is dry.Be used for dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation.
Fructus Ligustri Lucidi: nourishing the liver and kidney, black hair makes eye bright.Be used for vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
Fructus Atriplicis Sibiricae: suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.Be used for the dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, diseases such as skin pruritus.
Radix Clematidis: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Be used for rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, the bone larynx of choking with sobs.
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping.
Radix Saposhnikoviae: deliver, dispel the wind, win and wet, pain relieving.
Fructus Lycii: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, blood-enriching tranquillizing, promoting the production of body fluid to quench thirst, nourishing the lung to arrest cough.
Herba Spirodelae: the hot carbuncle of row when controlling, macule is not saturating, wind heat pain rash, skin pruritus, edema, amenorrhea, the skin ulcer tinea, erysipelas is scalded.
Flos Carthami: the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.Be used for that amenorrhea, dysmenorrhea, lochia are not all right, lump in the abdomen mass in the abdomen, traumatic injury.
Herba Lysimachiae: heat clearing away, diuresis, antitussive, detumescence, detoxifcation.
Fructus Mori: tonifying liver, kidney tonifying relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid.The treating the liver kidney yin is lost, and send and take off, constipation, order is dark, tinnitus, former infections, articular instability.
Agkistrodon: control the lung-wind syndrome nasal obstruction, vitiligo, scrofula infections, speckle and floating urticaria.
Semen Cuscutae: nourishing the liver and kidney, the controlling nocturnal emission with astringent drugs reducing urination, antiabortive, make eye bright antidiarrheal.Be used for impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
The Radix Angelicae Dahuricae: dispel the wind dampness, detumescence, pain relieving.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Borneolum Syntheticum: heat-clearing and toxic substances removing, erosion prevention and muscle growing effect
After the present invention made up said medicine, drug effect had synergism, and in the therapy for vitiligo process, effect is remarkable.Reach the purpose for the treatment of both the principal and secondary aspects of a disease.The leukodermic Chinese medicine composition of this kind oral administration and externally used for curing is through clinical 100 example checkings, effective percentage 89.5%, cure rate 20.1%.
Model case:
Case one: Mrs Ceng, 40 years old, suffer from the Secondary cases vitiligo, symptom is found at left facial part, two superciliums have white macula, waist has the bulk white macula, eats many medicines, tries a variety of therapies, but poor effect, when the patient loses the confidence, recognized afterwards that the leukodermic Chinese medicine composition effect of this kind oral administration and externally used for curing was very good nearly, just had the phychology of trying in arms, after beginning to take three courses of treatment, effect is very definite, and the state of an illness is controlled fully, and the patient sets up confidence after seeing effect, mood changes calmness over to, full of hope, serve on recovery from illness after two months, so far not recurrence.
Case two: Mrs Hou, 36 years old, see that the year before white macula appears in hand, be diagnosed as vitiligo in local hospital, taking the leukodermic medicine of treatment does not have obvious curative effects.After taking the leukodermic Chinese medicine composition one and a half months of this kind oral administration and externally used for curing afterwards, a large amount of melanin in white macula place generate, and are slightly darker than normal skin color.Took three months, the white macula complete obiteration, former white macula place color is slightly different with the normal colour of skin.Continue to take medicine, now withdrawn any medicine, white macula complete obiteration so far, the same normal human skin of color.
Case three: Mrs sentence, 26 years old, suffered from vitiligo 4 years, stumbling on during beginning grows small particles in one's ear with in the eyebrow, and beginning is not taken notice of yet, is not gone to think more yet.Three April small particles in gradually expansion, become whiter.White macula as the coin size also appears in facial and other position of health, and is superficial, is general property vitiligo after diagnosing.It is not very few that the leukodermic Western medicine of relevant treatment, Chinese medicine are eaten, 1 year in the past, be exactly not get better, begin to take the leukodermic Chinese medicine composition of this kind oral administration and externally used for curing upon somebody's introduction, controlled the white macula diffusion and stretched very soon after medication two courses of treatment, skin pigment forms after the 3rd course of treatment, white macula is light brown transformation after five courses of treatment, and fusion is dwindled, and skin gloss occurs.White macula all disappears after six courses of treatment.
Case four: Mr. Gao, 27 years old, the little white macula of grain of rice sample appearred in forehead at the beginning of 2004.Do not do any processing, white macula extends to the wing of nose after February, is diagnosed as vitiligo.Once wiped outward with photosensitization therapy, cmm of simple prescription treatment and benefit bone cream.Not control.After be extended down to hand and abdomen back, in JIUYUE, 2005 is diagnosed as vitiligo and distributes type.Take three courses of treatment of the leukodermic Chinese medicine composition of this kind oral administration and externally used for curing, the white macula area obviously dwindles, and the state of an illness is controlled, and white macula place color is close with normal skin after six courses of treatment.Continue to take medicine, after four months, the same ordinary person of skin satisfies drug withdrawal.So far do not see recurrence.
Case five: Mr. Cao, 50 years old, the patient suffered from vitiligo before 3 years, the white macula left forehead that distributes, shirtfront and abdominal part, the all about yuan coin-size of abdominal part white macula, through taking the leukodermic Chinese medicine composition of this kind oral administration and externally used for curing, produce effects after two courses of treatment, continue to take convention amount, white macula recovers gradually to the normal colour of skin, and three place's white maculas of patient are different phenomenons: the white macula of volume forward part one yuan size is to recover to the normal colour of skin, and the white macula of front part monobasic money size is rubescent, hair follicle is clear, the black island occurs and recover gradually, the white macula of abdominal part is to reduce the scope gradually and recover and heal to the normal colour of skin.Through the recovery from illness of six course of therapy, after continue to take and consolidate curative effect 1 course of treatment, recurrence so far.
Case six: Mrs Cui, 19 years old, make a definite diagnosis in June, 2005 and to suffer from the posteriority vitiligo.Symptom: by the facial cheeks, the many places white macula appears in nose bridge, very low the seeking medical advice in many ways of patient's emotion do not healed, and the head of a family is also very worried.After upon somebody's introduction, buy with the phychology of trying to see and to take the leukodermic traditional Chinese medicine composition for treating of this kind oral administration and externally used for curing.After treating two courses of treatment, sb.'s illness took a favorable turn 80%, is almost recovered the 5th course of treatment continuing to take.Continue to strengthen two courses of treatment, so far not recurrence.
The specific embodiment
Example one: making raw materials of effective components by following weight portion is: Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Fructus Ligustri Lucidi 15, Fructus Psoraleae 15, Radix Polygoni Multiflori 30, Fructus Atriplicis Sibiricae 30, Semen Sesami Nigrum 30, Radix Saposhnikoviae 10, the Rhizoma Atractylodis Macrocephalae 10, Fructus Lycii 10, Flos Carthami 10, Agkistrodon 3, Radix Clematidis 12, Herba Lysimachiae 20, Fructus Mori 6, Fructus Psoraleae 30, Semen Cuscutae 10, the Radix Angelicae Dahuricae 10 and Borneolum Syntheticum 2.
Preparation and instructions of taking: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Ligustri Lucidi, Fructus Psoraleae, Radix Polygoni Multiflori, Fructus Atriplicis Sibiricae, Semen Sesami Nigrum, Radix Saposhnikoviae, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii, Flos Carthami, Agkistrodon, Radix Clematidis, Herba Lysimachiae and Fructus Mori are put into marmite, add 500 milliliters in water, be decocted in water for oral dose, potion on the one, potion is taken at twice.With the back external of 60 ° of soaking in Chinese liquor one week, every day is twice outer skin lesion position of wiping sooner or later with Fructus Psoraleae, Semen Cuscutae, the Radix Angelicae Dahuricae and Borneolum Syntheticum, and suitably friction increases sunshine, obvious erythema vesicle degree of being to occur.Ten days is a course of treatment.

Claims (1)

1. leukodermic Chinese medicine composition of oral administration and externally used for curing, it is characterized in that, making raw materials of effective components by following weight portion is: Radix Angelicae Sinensis 10, Rhizoma Chuanxiong 10, Fructus Ligustri Lucidi 15, Fructus Psoraleae 15, Radix Polygoni Multiflori 30, Fructus Atriplicis Sibiricae 30, Semen Sesami Nigrum 30, Radix Saposhnikoviae 10, the Rhizoma Atractylodis Macrocephalae 10, Fructus Lycii 10, Flos Carthami 10, Agkistrodon 3, Radix Clematidis 12, Herba Lysimachiae 20, Fructus Mori 6, Fructus Psoraleae 30, Semen Cuscutae 10, the Radix Angelicae Dahuricae 10 and Borneolum Syntheticum 2, wherein above-mentioned Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Ligustri Lucidi, Fructus Psoraleae, Radix Polygoni Multiflori, Fructus Atriplicis Sibiricae, Semen Sesami Nigrum, Radix Saposhnikoviae, the Rhizoma Atractylodis Macrocephalae, Fructus Lycii, Flos Carthami, Agkistrodon, Radix Clematidis, Herba Lysimachiae and Fructus Mori are for taking Fructus Psoraleae orally, Semen Cuscutae, the Radix Angelicae Dahuricae and Borneolum Syntheticum are external.
CN2007100142233A 2007-04-04 2007-04-04 Oral externally-applied Chinese medicinal composition for treating leucoderma Expired - Fee Related CN101028375B (en)

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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101288738B (en) * 2008-06-19 2011-05-25 魏永全 Production method of medicine for treating vitiligo
CN101574431B (en) * 2009-06-17 2010-09-08 赵富刚 Drug for treating vitligo
CN102228538A (en) * 2011-06-21 2011-11-02 王伯寅 Traditional Chinese medicine preparation for treating vitiligo
CN102319365B (en) * 2011-08-31 2013-04-24 刘巧 Shouwu capsules
CN104257781A (en) * 2014-09-27 2015-01-07 唐国萍 External preparation for treating vitiligo
CN104491170A (en) * 2014-11-23 2015-04-08 溧阳市天目湖大紫王葡萄专业合作社 Traditional Chinese medicinal composition for treating pathogenic wind type leucoderma
CN104524373A (en) * 2014-12-21 2015-04-22 葛文涛 Traditional Chinese medicine combination used for leucoderma and preparation method thereof
CN108578513A (en) * 2018-06-24 2018-09-28 熊明彬 A kind of Chinese medicine preparation for treating leucoderma

Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1080862A (en) * 1993-06-05 1994-01-19 郭念筠 Treat leukodermic medicine

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN1080862A (en) * 1993-06-05 1994-01-19 郭念筠 Treat leukodermic medicine

Non-Patent Citations (1)

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周守红等.中药内服联合其他外治法治疗白癜风.中国美容医学16 2.2007,16(2),275-277. *

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