CN104491170A - Traditional Chinese medicinal composition for treating pathogenic wind type leucoderma - Google Patents
Traditional Chinese medicinal composition for treating pathogenic wind type leucoderma Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
A traditional Chinese medicinal composition for treating pathogenic wind type leucoderma comprises an oral medicine and an external medicine which are used cooperatively. The oral medicine is prepared from the following medicinal raw materials, by weight, 9-30 parts of ramulus mori, 3-12 parts of periostracum cicadae, 4.5-18 parts of catnip, 4.5-18 parts of divaricate saposhnikovia root, 3-20 parts of cassia twig, 5-20 parts of white peony root, 3-18 parts of safflower, 6-24 parts of matrimony vine, 10-30 parts of mulberry, 6-24 parts of bighead atractylodes rhizome and 1.5-18 parts of licorice. The external medicine is prepared from the following medicinal raw materials, by weight, 6-18 parts of fructus tribuli, 3-18 parts of xanthium and 9-24 parts of zaocys dhumnade. After one treatment course, total effective rate reaches 88%.
Description
Technical field
The present invention relates to one to treat outside ailment said due to cold or exposure and attack the leukodermic Chinese medicine composition of type.Specifically, being take Chinese herbal medicine as preparation prepared by raw material.The invention still further relates to the external medicine composition simultaneously used with this oral traditional Chinese medicine composition.
Background technology
Vitiligo is acquired skin pigment depigmentation disease a kind of common day after tomorrow, show as skin limitation or general property depigmentation speckle, be tryrosinase system in the melanin due to illing skin and hair follicle hypofunction caused by, modern medicine due to etiology unknown so easily examine and refractory.Although this disease does not bring sensual misery to patient, but the skin lesion due to primary disease directly affects the outward appearance appearance of people, great stress and psychological burden is brought to patient, many negative factors are brought to the aspect such as life, work, social activity of patient, thus have impact on the quality of life of patient.But, to the treatment of primary disease, there is no definite effective Therapeutic Method up to now
The etiology and pathogenesis of Chinese medicine to primary disease has suitable research.There is speech in Qing Dynasty's " Yizong Jinjian surgery heart method gist ": this card color in face and neck bleaches suddenly, shape class white macula, not sufferings.Being fought mutually to cause in skin by ailment said due to cold or exposure makes qi-blood disharmony, and treating should early, if follow with the passing of time, notably to prolong and all over.Attack outside its ailment said due to cold or exposure and cause the qi-blood disharmony cause of disease and say, said one of reason of primary disease.Chinese invention patent application CN 102698033A discloses one and treats leukodermic Chinese medicine composition.Said composition forms with external two groups of medicines by taking orally: endo-medicine is made up of Radix Rehmanniae, Fructus Corni, Rhizoma Dioscoreae, Herba Euphorbiae Helioscopiae, Poria, Fructus Psoraleae; External used medicine is made up of Fructus Psoraleae, Lithargyrum, sulfur, inside and outside rule together, have liver and kidney tonifying, regulate the flow of vital energy and blood, invigorating striae of the skin effect.This invention is not for attacking type vitiligo outside ailment said due to cold or exposure.
Summary of the invention
The object of the present invention is to provide one to treat outside ailment said due to cold or exposure and attack the leukodermic Chinese medicine composition of type.
The present invention selects 11 herbal medicines such as Ramulus Mori, Periostracum Cicadae, Herba Schizonepetae, Radix Saposhnikoviae, Ramulus Cinnamomi, the Radix Paeoniae Alba, Flos Carthami, Fructus Lycii, Fructus Mori, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae to carry out prescription according to the principle of differentiation of tcm.The micro-hardship of Ramulus Mori is put down, and returns Liver Channel, wind-damp dispelling, sharp joint; Periostracum Cicadae is sweet cold, returns lung Liver Channel, loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic; The pungent tepor of Herba Schizonepetae, returns lung Liver Channel, induce sweat loose wind, rash; Radix Saposhnikoviae Xin Ganwen, returns bladder liver spleen channel, and inducing diaphoresis to dispel wind, victory are wet, relieving convulsion; Four medicine compounds, wind dispelling heresy is gone out.Ramulus Cinnamomi Xin Ganwen, GUIXIN lung bladder, relieving the exterior syndrome by diaphoresis, warming the meridian for promoting the flow of YANG QI; Radix Paeoniae Alba picric acid is slightly cold, and returns liver spleen channel, the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG; Two medicines share, harmonizing yingfen and weifen, make QI and blood must be with.Disharmony between QI and blood and the hyperamization stasis of blood, the pungent temperature of Flos Carthami, GUIXIN Liver Channel, invigorates blood circulation with dissipating blood stasis.Fructus Lycii is sweet flat, returns Liver and kidney warp, nourishing the liver and kidney, replenishing vital essence to improve eyesight; Fructus Mori is sweet cold, GUIXIN Liver and kidney warp; Nourishing YIN and supplementing blood, promote the production of body fluid, intestine moistening; The bitter sweet temperature of the Rhizoma Atractylodis Macrocephalae, returns taste warp, invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive; The first day after tomorrow must support, righting and eliminating evil.Radix Glycyrrhizae is sweet flat, and GUIXIN lung taste warp, helps Rhizoma Atractylodis Macrocephalae invigorating the spleen and replenishing QI and coordinating the actions of various ingredients in a prescription.
The each amounts of components of the present invention effect within the scope of following weight parts is better:
Ramulus Mori 9 ~ 30 parts, Periostracum Cicadae 3 ~ 12 parts, Herba Schizonepetae 4.5 ~ 18 parts, Radix Saposhnikoviae 4.5 ~ 18 parts, Ramulus Cinnamomi 3 ~ 20 parts, the Radix Paeoniae Alba 5 ~ 20 parts, 3 ~ 18 parts, Flos Carthami, Fructus Lycii 6 ~ 24 parts, 10 ~ 30 parts, Fructus Mori, the Rhizoma Atractylodis Macrocephalae 6 ~ 24 parts, 1.5 ~ 18 parts, Radix Glycyrrhizae.
Instant component consumption can also be: Ramulus Mori 12 ~ 25 parts, Periostracum Cicadae 5 ~ 9 parts, Herba Schizonepetae 6 ~ 12 parts, Radix Saposhnikoviae 6 ~ 12 parts, Ramulus Cinnamomi 6 ~ 15 parts, the Radix Paeoniae Alba 9 ~ 15 parts, Flos Carthami 6 ~ 15, Fructus Lycii 9 ~ 18 parts, 15 ~ 25 parts, Fructus Mori, the Rhizoma Atractylodis Macrocephalae 9 ~ 18 parts, 3 ~ 15 parts, Radix Glycyrrhizae.
Be preferably: Ramulus Mori 15 parts, Periostracum Cicadae 6 parts, Herba Schizonepetae 9 parts, Radix Saposhnikoviae 9 parts, Ramulus Cinnamomi 10 parts, the Radix Paeoniae Alba 10 parts, 9 parts, Flos Carthami, Fructus Lycii 12 parts, 15 parts, Fructus Mori, the Rhizoma Atractylodis Macrocephalae 12 parts, 9 parts, Radix Glycyrrhizae.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations, such as: decoction, medicinal tea, powder, pill, tablet, oral liquid, unguentum, capsule etc.
The present invention selects natural drug to be raw material, and each component meets pharmaceutical control law regulation.Utilize the comprehensive function treatment vitiligo of each taste Chinese medicine, without chemical addition agent, harmless to human non-toxic.
In order to reach better therapeutic effect, the present invention discloses a kind of topical composition, said composition is by Fructus Atriplicis Sibiricae, Fructus Xanthii, Zaocys.Fructus Atriplicis Sibiricae is worked hard tepor, slightly poisonous, returns Liver Channel, has suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic effect; The arduous temperature of Fructus Xanthii, poisonous, return lung meridian, the wind that can fall apart dehumidifying, clearing the nasal passage; Zaocys: Gan Ping, returns Liver Channel, dispels the wind, dredging collateral, relieving convulsion.Three medicines share, and make tincture external, gather the effect of eliminating blood stasis and removing ecchymoses of dispeling the wind altogether.
The each amounts of components of this topical composition effect within the scope of following weight parts is better: Fructus Atriplicis Sibiricae 6 ~ 18 parts, Fructus Xanthii 3 ~ 18 parts, Zaocys 9 ~ 24 parts.
This topical composition amounts of components can also be: Fructus Atriplicis Sibiricae 9 ~ 15 parts, Fructus Xanthii 6 ~ 15 parts, Zaocys 12 ~ 21 parts.
Be preferably: Fructus Atriplicis Sibiricae 9 parts, Fructus Xanthii 9 parts, Zaocys 15 parts.
For showing that Chinese medicine of the present invention is to the leukodermic therapeutic effect of type of attacking outside ailment said due to cold or exposure, the present invention have passed through 50 routine system clinical observations: patient 50 example, wherein man 24 example, female 26 example; 18 ~ 60 years old age, wherein less than 20 years old person 5 example, 20 examples between 21 ~ 30 years old, 8 examples between 31 ~ 40 years old, 12 examples between 41 ~ 50 years old, 5 examples between 51 ~ 60 years old.Patient shows as color in face and neck more and suddenly bleaches, shape class white macula, and without sufferings, PD is fast, companion red tongue, Tai Bai or Huang, rapid pulse etc.For the effect of ruling together inside and outside verifying, during clinical observation, 50 routine patients are divided into two groups at random, first group of 25 people only takes oral medicine, and second group of 25 people's oral administration and externally carries out simultaneously.
Instructions of taking: internal composition adopts the Chinese medicine in embodiment 5, is decocted in water for oral dose, day potion, within three months, be a course for the treatment of.Topical composition adopts the Chinese medicine pulverize in embodiment 10, and used time Oleum Sesami is in harmonious proportion, and puts on the skin, every day three times with cotton swab outside dipping in.
Curative effect determinate standard
According to " vitiligo Clinical typing and the criterion of therapeutical effect " of Dermatology Professional Committee of CAIM (Chinese Association Of Integrative Medicine) pigment disease group in combination of Chinese and Western medicine skin pigment disease investigation club of in December, 2003 China revision.Recovery from illness: white macula disappears completely, recovers normal skin tone.Effective: white macula reduces, recover normal skin tone more than 50%.Effective: white macula reduces, recover normal skin tone 10% ~ 49%.Invalid: white macula reduces, recover normal skin tone less than 10%.
Result
After the course for the treatment of, in first group of 25 routine patient, effective 7 examples, effective 10 examples, invalid 8 examples, total effective rate 68%; In the second routine patient in composition portion 25, effective 10 examples, effective 12 examples, invalid 3 examples, total effective rate 88%;
Detailed description of the invention
Internal composition takes raw material (part) by following proportioning
1, Ramulus Mori 9, Periostracum Cicadae 3, Herba Schizonepetae 4.5, Radix Saposhnikoviae 4.5, Ramulus Cinnamomi 3, the Radix Paeoniae Alba 5, Flos Carthami 3, Fructus Lycii 6, Fructus Mori 10, the Rhizoma Atractylodis Macrocephalae 6, Radix Glycyrrhizae 1.5;
2, Ramulus Mori 30, Periostracum Cicadae 12, Herba Schizonepetae 18, Radix Saposhnikoviae 18, Ramulus Cinnamomi 20, the Radix Paeoniae Alba 20, Flos Carthami 18, Fructus Lycii 24, Fructus Mori 30, the Rhizoma Atractylodis Macrocephalae 24, Radix Glycyrrhizae 18;
3, Ramulus Mori 12, Periostracum Cicadae 5, Herba Schizonepetae 6, Radix Saposhnikoviae 6, Ramulus Cinnamomi 6, the Radix Paeoniae Alba 9, Flos Carthami 6, Fructus Lycii 9, Fructus Mori 15, the Rhizoma Atractylodis Macrocephalae 9, Radix Glycyrrhizae 3;
4, Ramulus Mori 25, Periostracum Cicadae 9, Herba Schizonepetae 12, Radix Saposhnikoviae 12, Ramulus Cinnamomi 15, the Radix Paeoniae Alba 15, Flos Carthami 15, Fructus Lycii 18, Fructus Mori 25, the Rhizoma Atractylodis Macrocephalae 18, Radix Glycyrrhizae 15;
5, Ramulus Mori 15, Periostracum Cicadae 6, Herba Schizonepetae 9, Radix Saposhnikoviae 9, Ramulus Cinnamomi 10, the Radix Paeoniae Alba 10, Flos Carthami 9, Fructus Lycii 12, Fructus Mori 15, the Rhizoma Atractylodis Macrocephalae 12, Radix Glycyrrhizae 9.
This internal composition can make the multiple dosage forms such as decoction, medicinal tea, powder, pill, tablet, oral liquid, unguentum, capsule by needs of patients.
Topical composition takes raw material (kilogram) by following proportioning
6, Fructus Atriplicis Sibiricae 6, Fructus Xanthii 3, Zaocys 9.
7, Fructus Atriplicis Sibiricae 18, Fructus Xanthii 18 parts, Zaocys 24.
8, Fructus Atriplicis Sibiricae 9, Fructus Xanthii 6, Zaocys 12.
9, Fructus Atriplicis Sibiricae 15, Fructus Xanthii 15, Zaocys 21.
10, Fructus Atriplicis Sibiricae 9 parts, Fructus Xanthii 9 parts, Zaocys 15 parts.
This compositions pulverize, Oleum Sesami mediation external.
Claims (5)
1. treat outside ailment said due to cold or exposure and attack the leukodermic Chinese medicine composition of type, it is characterized in that comprising simultaneously with the use of oral medicine and medicine for external use;
Oral medicine is made up of the crude drug of following weight portion:
Ramulus Mori 9 ~ 30 parts, Periostracum Cicadae 3 ~ 12 parts, Herba Schizonepetae 4.5 ~ 18 parts, Radix Saposhnikoviae 4.5 ~ 18 parts, Ramulus Cinnamomi 3 ~ 20 parts, the Radix Paeoniae Alba 5 ~ 20 parts, Flos Carthami 3 ~ 18, Fructus Lycii 6 ~ 24 parts, 10 ~ 30 parts, Fructus Mori, the Rhizoma Atractylodis Macrocephalae 6 ~ 24 parts, 1.5 ~ 18 parts, Radix Glycyrrhizae;
Medicine for external use is made up of the crude drug of following weight portion:
Fructus Atriplicis Sibiricae 6 ~ 18 parts, Fructus Xanthii 3 ~ 18 parts, Zaocys 9 ~ 24 parts.
2. attack the leukodermic Chinese medicine composition of type outside treatment ailment said due to cold or exposure according to claim 1, it is characterized in that oral medicine is made up of the crude drug of following weight portion:
Ramulus Mori 12 ~ 25 parts, Periostracum Cicadae 5 ~ 9 parts, Herba Schizonepetae 6 ~ 12 parts, Radix Saposhnikoviae 6 ~ 12 parts, Ramulus Cinnamomi 6 ~ 15 parts, the Radix Paeoniae Alba 9 ~ 15 parts, 6 ~ 15 parts, Flos Carthami, Fructus Lycii 9 ~ 18 parts, 15 ~ 25 parts, Fructus Mori, the Rhizoma Atractylodis Macrocephalae 9 ~ 18 parts, 3 ~ 15 parts, Radix Glycyrrhizae.
3. attack the leukodermic Chinese medicine composition of type outside treatment ailment said due to cold or exposure according to claim 1, it is characterized in that oral medicine is made up of the crude drug of following weight portion:
Ramulus Mori 15 parts, Periostracum Cicadae 6 parts, Herba Schizonepetae 9 parts, Radix Saposhnikoviae 9 parts, Ramulus Cinnamomi 10 parts, the Radix Paeoniae Alba 10 parts, 9 parts, Flos Carthami, Fructus Lycii 12 parts, 15 parts, Fructus Mori, the Rhizoma Atractylodis Macrocephalae 12 parts, 9 parts, Radix Glycyrrhizae.
4. attack the leukodermic Chinese medicine composition of type outside treatment ailment said due to cold or exposure according to claim 1, it is characterized in that medicine for external use is made up of the crude drug of following weight portion:
Fructus Atriplicis Sibiricae 9 ~ 15 parts, Fructus Xanthii 6 ~ 15 parts, Zaocys 12 ~ 21 parts.
5. attack the leukodermic Chinese medicine composition of type outside treatment ailment said due to cold or exposure according to claim 1, it is characterized in that medicine for external use is made up of the crude drug of following weight portion:
Fructus Atriplicis Sibiricae 9 parts, Fructus Xanthii 9 parts, Zaocys 15 parts.
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Citations (4)
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| CN1185970A (en) * | 1998-01-06 | 1998-07-01 | 宋守金 | External use medicine for vitiligo |
| CN1483469A (en) * | 2003-07-21 | 2004-03-24 | 马柏林 | Baidianxiao treaditional Chinese medicine for treating vitiligo and preparation method thereof |
| CN1907332A (en) * | 2006-08-02 | 2007-02-07 | 胡彩芳 | Decoction preparation for treating cold type urticaria and its preparation process |
| CN101028375A (en) * | 2007-04-04 | 2007-09-05 | 孙立新 | Oral externally-applied Chinese medicinal composition for treating leucoderma |
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2014
- 2014-11-23 CN CN201410676280.8A patent/CN104491170A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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