CN100571678C - Semen Litchi extract is killed application in the face cleaning product of acarid and fungus in preparation - Google Patents
Semen Litchi extract is killed application in the face cleaning product of acarid and fungus in preparation Download PDFInfo
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Abstract
The invention belongs to the household chemicals field, specifically disclose a kind of face cleaning product, it comprises facial milk cleanser, cleansing milk and face washing mud.Face cleaning product of the present invention is to be that raw material is made by Semen Litchi extract.This face cleaning product has the effect of killing acarid and killing fungus, has good market prospect.
Description
[technical field]
The invention belongs to the household chemicals technical field, be specifically related to the application of Semen Litchi extract in the face cleaning product of killing acarid and fungus.
[background technology]
Semen Litchi is the mature seed of Sapindaceae aiphyllium plant Fructus Litchi (Litchi chinsis Sonn.).Main product in Fujian, ground such as Guangdong, Guangxi.Pluck mature fruit summer, remove peel and meat aril, clean, dry.Give birth to or saline process usefulness.Time spent smashes.Semen Litchi acrid in the mouth, little hardship, temperature.Return liver, stomach through being mainly used in colicky, painful and swollen testis.This product catharsis of working hard has the merit of depressed liver-energy dispersing and QI regulating, promoting QI to circulate and dispersing the agglomeration of the pathogens, dispersing cold for relieving pain.Semen Litchi is controlled colic of cold type pain, can be equal to usefulness with Fructus Foeniculi, Fructus Evodiae, Semen Citri Reticulatae, as the hernia internal diabetes ball of " Beijing's Chinese traditional patent formulation selected works ".Control painful and swollen testis, many and Semen Citri Reticulatae, Fructus Toosendan are equal to usefulness.Semen Litchi also can be used for gastral cavilty pain of a specified duration, dysmenorrhea, puerperal abdonimal pain.It is logical that the hot row of this product hardship is let out temperature, and dispersing the stagnated liver-QI for regulating the stomach, regulating QI to relieve pain effect are arranged.The gastral cavilty pain of a specified duration of Semen Litchi treating the liver stagnation of QI knot, incoordination between the liver and stomach can be ground clothes into powder with the Radix Aucklandiae, looses as the Jing-Yue Complete Works litchi is fragrant, the dysmenorrhea and the puerperal abdonimal pain of the strongly fragrant qi depression to blood stasis for the treatment of the liver, can grind clothes into powder with perfume (or spice) limit, diffusing bitterly as " married woman's good recipe " stannum, or be equal to usefulness with Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Bupleuri.
Semen Litchi is Long Circle or oval, and is slightly flat, long 1.5～2.2cm, diameter 0.6～1.5cm.Surface brownish red or purple brown, glossy, slightly cave in and insertion waves.One end has the hilum of similar round or oval yellowish-brown, diameter 5～7mm.Matter is hard, cuts 2 of the visible plump cotyledons in back open with water infiltration, and orange-yellow or pale brown color is combined closely with kind of a skin.Feeble QI, it is little sweet, bitter, puckery to distinguish the flavor of.Big, full, bright person is good with grain.Its microscopical identification is: Semen Litchi (middle part) cross section: all plant the chrotoplast wall and be pale brown color.Plant the exocuticle cell extend radially of skin.About 10～15 row of parenchyma cell are arranged in it, and cell tangentially prolongs, the visible sparse Kong Wen that has.Brown oil cell similar round or Long Circle.The interrupted annular arrangement of vascular bundle.Decadent near the several layers of parenchyma cell of planting the skin epidermis, cell shrinkage, the gap is big.The endepidermis of planting skin is 1 row parenchyma cell, and is flat, different in size.Be full of starch grain in the parenchyma cell of cotyledon, and as seen have brown oil cell to be dispersed in.
American documentation literature US2004/0101508A1 discloses the purposes of extract aspect cosmetics and medicine of Fructus Litchi.Chinese patent literature (200410022559) provides Fructus Litchi extract and preparation method thereof, and this invention also provides the application of this Fructus Litchi extract in medicine, health food and cosmetics.But to the deep development of Semen Litchi extract, especially Semen Litchi extract does not have document to mention in the application of face cleaning product, does not have product open yet.Zheng Linying etc. reported Semen Litchi have suppress hbs antigen, effect (Chinese medicine journal, 1998 (5): 51-53) such as blood sugar lowering, enhancing mouse liver albumen and RNA be synthetic; (Chinese Journal of New Drugs, 2000 (1): 14-16) reported that also Semen Litchi has blood lipid regulation and antioxidation such as Pan Jing clanging or clanking sound except above effect.
[summary of the invention]
The object of the present invention is to provide the Semen Litchi that is annual about 500,000 tons to turn waste into wealth, development and use are used to prepare face cleaning product, and this face cleaning product has the effect of killing acarid and killing fungus.
Another object of the present invention is to provide the face cleaning product preparation method.
Face cleaning product of the present invention is characterized in that described face cleaning product contains Semen Litchi extract.
Face cleaning product of the present invention is characterized in that described face cleaning product contains Semen Litchi extract and face cleaning product adjuvant.
Above-mentioned face cleaning product comprises facial milk cleanser, cleansing milk and face washing mud.
Above-mentioned face cleaning product, the Semen Litchi extract weight ratio in face cleaning product is 0.1-25%, preferred 0.1-15%, more preferably 0.5-10%, most preferably 0.5-5%.
Above-mentioned Semen Litchi extract is that the mixed solvent extraction of Semen Litchi with the second alcohol and water obtained.Semen Litchi extract among the present invention also can adopt commercially available product (existing at present Semen Litchi extract is sold), can also obtain by other organic solvents or water extraction.
Above-mentioned face cleaning product can also add Herba Leonuri extract, Radix Salviae Miltiorrhizae extract, Radix Angelicae Sinensis extract, Rhizoma Chuanxiong extract, Semen Tritici aestivi extract, Radix Polygoni Multiflori extract, Radix Ginseng extract, Margarita, Margarita micropowder, Rhizoma Atractylodis Macrocephalae extract, Fructus Lycii extract, Radix Saposhnikoviae extract, Radix Angelicae Dahuricae extract, Radix Astragali extract, Rhizoma Dioscoreae extract, Radix Rehmanniae extract, alfalfa extract, Sargassum extract, Aloe extract, Radix Arnebiae extract, the XINGTAO extract, Camellia extract, camomile extract, green algal extract, Radix Arnebiae extract, Radix Glycyrrhizae extract, Caulis Hederae Sinensis extract, Herba Euphrasiae Regelii extract, Radix Oenotherae erythrosepalae oil, Fructus Foeniculi extract, Rhizoma Zingiberis Recens extract, Semen Ginkgo extrac, Semen Vitis viniferae extract, the Radix Hamamelidis Mollis extract, Fructus Crataegi extract, citron extract, Radix Glycyrrhizae extract, Bulbus Lilii extract, the SONGGUOJU extract, Herba Plantaginis extract, Herba Rosmarini Officinalis extract, sage extract, in the Rhizoma Seu Herba Bergeniae extract one or more.
The preparation method of face cleaning product of the present invention is: water and alcoholic acid mixed solvent extraction were 1-3 time after Semen Litchi was pulverized, each 1-2 hour, the temperature of extracting is 40-75 ℃, concentrated after drying promptly gets Semen Litchi extract, with Semen Litchi extract add the dressing of face cleaning product, stirring and evenly mixing, fill promptly under the aseptic condition.
The water content of the Semen Litchi extract in the preparation method of above-mentioned face cleaning product is controlled at 2.5-3.5%.
Another purpose of the present invention is to provide Semen Litchi extract to kill application in the face cleaning product of acarid and fungus in preparation, the preparation method of wherein said Semen Litchi extract is: 500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrated, spray drying, promptly get Semen Litchi extract, water content is 3.5%, and described Semen Litchi extract weight ratio in face cleaning product is 0.1-25%.
Preferred weight ratio is 0.1-15% described in the above-mentioned application; More preferably 1-10%, most preferably 1-5%.
Face cleaning product described in the above-mentioned application is facial milk cleanser or cleansing milk.
The preparation method of face cleaning product is described in the above-mentioned application: with the dressing of above-mentioned Semen Litchi extract adding face cleaning product, and stirring and evenly mixing, fill is promptly under the aseptic condition.
Because Guangdong and Guangxi Provinces, Fujian and Taiwan Fructus Litchi output are huge, many mountain areas, the Fructus Litchi place of production and hills, have inconvenient traffic, and Fructus Litchi requires very harsh to storage and traffic condition, often occur going mouldy owing to Fructus Litchi can not be caused by place of production outward transport in time, at this moment pulp and Fructus Litchi kind skin have not all had value, Semen Litchi can also add in the face cleaning product by drying, sterilization and pulverizing back or processing extraction only, turn waste into wealth, produce bigger economic worth, also can increase farmers' income for the Fructus Litchi grower retrieves a loss.
China's Fructus Litchi output is huge, and Fructus Litchi output was about 1,500,000 tons in 2005, and resource is very abundant, because the difference of Fructus Litchi kind accounts for Fructus Litchi gross weight 1/3 with Semen Litchi and calculates, annual China just has 500,000 tons of Semen Litchi resources to develop.From the raw material as face cleaning product, Semen Litchi has than the better advantage of Fructus Litchi, says that from content of effective difference of them is little, but because Fructus Litchi is in the fruit outside, contacts with air, and active component is oxidized easily; And Fructus Litchi is as a kind of fruit, by people edible after, peel is difficult to collect, the gross weight ratio that Fructus Litchi accounts for litchi fruits is little; And Semen Litchi weight is big, is easy to collect after eating; Directly Semen Litchi is taken out when also having businessman to produce canned litchi, be more convenient for the collection of Semen Litchi like this.
Fructus Litchi is since ancient times owing to the well-known phrase of " rides the human society imperial concubine laughs at; nobody knows Fructus Litchi " fires one's imagination, become a kind of and beautiful fruit of becoming attached to, Semen Litchi really is used to beautify people's life, also be not used in the preparation face cleaning product but also have no talent at present.
The present invention verifies by experiment, the performance of face cleaning product among the present invention is killed acarid and killed that fungus kills acarid and kill the fungus effect is that various compositions comprehensively play a role in the Semen Litchi extract, rather than a certain or a certain compounds plays a role, therefore Semen Litchi extract is as a kind of raw material of face cleaning product, has the incomparable effect of other face cleaning product, especially going to kill acarid and killing to have significant improvement effect aspect the fungus, in addition, Semen Litchi extract also has favorable compatibility, also can make face cleaning product by compatibility with other plant or plant extract, also have the effect of killing acarid and killing fungus, wherein the effect of Semen Litchi extract is indispensable.
The inventor attempts to adopt the active component of the extract of litchi rind as face cleaning product, but experimental results show that the face cleaning product that litchi rind is made does not possess the obvious effect of killing acarid and killing fungus.
[specific embodiment]
Following embodiment further describes the present invention, but described embodiment only is used to illustrate the present invention rather than restriction the present invention.
The preparation of embodiment 1-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 1-2 hour at every turn 2-3 time, the temperature of extracting is 55-65 ℃, concentrates the back under 60 ℃ of conditions, vacuum drying oven 6 hours, promptly get Semen Litchi extract, water content is 2.5%.
The preparation of embodiment 2-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and ethanol and being 1: 3 are got 1-2 hour at every turn 2-3 time, the temperature of extracting is 55-70 ℃, concentrates the back under 80 ℃ of conditions, vacuum drying oven 5 hours, promptly get Semen Litchi extract, water content is 2.9%.
The preparation of embodiment 3-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 2-3 time, and each 1-2 hour, the temperature of extraction was 55-70 ℃, and concentrated, spray drying promptly get Semen Litchi extract, and water content is 3.5%.
Embodiment 4-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 1) of 1g, behind the irradiation sterilization, after adding 10g sorbitol, 30g glycerol, 30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 5-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 2) of 5g, behind the irradiation sterilization, after adding 10g sorbitol, 30g glycerol, 30g cetomacrogol 1000,50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 6-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 3) of 10g, behind the irradiation sterilization, after adding 10g sorbitol, 30g polyethylene glycol 1500,30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 7-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 1) of 50g, behind the irradiation sterilization, after adding 10g sorbitol, 30g glycerol, 30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 8-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 3) of 100g, behind the irradiation sterilization, after adding 10g sorbitol, 30g polyethylene glycol 1500,30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus supplies 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 9-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 3) of 150g, behind the irradiation sterilization, after adding 10g sorbitol, 5g Semen Tritici aestivi extract, 30g polyethylene glycol 1500,30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 10-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 3) of 250g, behind the irradiation sterilization, after adding 10g sorbitol, 5g Radix Angelicae Sinensis extract, 30g polyethylene glycol 1500,30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 11-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 3) of 150g, behind the irradiation sterilization, after adding 10g sorbitol, 30g polyethylene glycol 1500,30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 12-contains the preparation of Semen Litchi extract facial milk cleanser
Get the Semen Litchi extract (embodiment 3) of 300g, behind the irradiation sterilization, after adding 10g sorbitol, 30g polyethylene glycol 1500,30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 13-contains the preparation of Semen Litchi extract cleansing milk
Get the Semen Litchi extract (embodiment 1) of 50g, behind the irradiation sterilization, after adding 10g sorbitol, 10g Margarita micropowder, 30g glycerol, 30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Embodiment 14-contains the preparation of Semen Litchi extract cleansing milk
Get the Semen Litchi extract (embodiment 1) of 50g, behind the irradiation sterilization, after adding 10g sorbitol, 10g Aloe extract, 30g glycerol, 30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
The preparation of Comparative Examples 1-litchi rind extract
1 kilogram of litchi rind, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and ethanol and being 1: 3 are got 1-2 hour at every turn 2-3 time, the temperature of extracting is 40-70 ℃, concentrates the back under 50 ℃ of conditions, vacuum drying oven 10 hours, promptly get the litchi rind extract, extraction ratio is 8.5%.
The preparation of Comparative Examples 2-litchi rind extract
1 kilogram of litchi rind, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and ethanol and being 3: 1 are got 3 times, and each 1-2 hour, the temperature of extraction was 40-70 ℃, concentrated, spray drying, promptly got the litchi rind extract, and extraction ratio is 9.9%.
Comparative Examples 3-contains the preparation of litchi rind extract cleansing milk
Get the litchi rind extract (Comparative Examples 1) of 50g, behind the irradiation sterilization, after adding 10g sorbitol, 30g glycerol, 30g imidazoles beautiful jade betanin, 50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Comparative Examples 4-contains the preparation of litchi rind extract facial milk cleanser
Get the litchi rind extract (Comparative Examples 2) of 100g, behind the irradiation sterilization, after adding 10g sorbitol, 30g glycerol, 30g cetomacrogol 1000,50g trialkyl methyl ammonium chloride and 0.5g methyl parahydroxybenzoate, surplus is supplied 1000g high-speed stirred mixing with pure water, fill is 10 packings, promptly.
Experimental example 1-human safety (skin irritation) test
1 test objective
Detection is tried the probability that thing causes the human body skin untoward reaction, and the effect of being tried thing is carried out preliminary assessment.
2 test basic principles
2.1 select qualified volunteer object on probation.
2.2 according to the type and the character of cosmetics, allow the actual use of experimenter be subjected to test product, tried the safety (skin irritation) of thing to human body with evaluation.
3 experimenters' selection
3.1 select volunteer that the Pass Test of 18-60 year requires as study subject.
3.2 can not select following situation person as the experimenter: a nearly week uses antihistaminic or uses immunosuppressant person in nearly one month; Tried the position in nearly two months and used any anti-inflammatory drug person; The experimenter suffers from the sick clinical person of not healing of inflammatory skin; The insulin-dependent diabetes patient; The asthma of receiving treatment or other chronic respiratory system diseases patient; The person that in nearly 6 months, accepts the anticancer chemotherapy; Immunodeficiency or autoimmune disease patient; Age of sucking or gravid woman; Bilateral mastectomy and bilateral axillary lymph knot excision person; Wait to try the position influences result of the test owing to cicatrix, pigment, atrophy, nevus flammeus or other flaw judgement person at skin; Participate in other clinical trial person; The extremely sensitive person of body constitution; Non-aspiration participant maybe can not finish specified content person by test requirements document.
4 dermoreaction grade scales: see Table 1.
Table 1 human body proof test skin adverse reaction grade scale
5 test methods
Press subject enrollment experimenter 20 examples (male's 10 examples, women's 10 examples), the time on probation is 1 month.On 3 days skin, labelling, be coated with same position with 0.5 * 0.5 centimetre of face cleaning product (embodiment 4-14) separate application in experimenter's forearm inboard at every turn.Observe 1 experimenter's dermoreaction every 1 day, press table 1 skin adverse reaction grade scale record result.
6 result safety evaluations:
Nothing 1 example has the skin adverse reaction more than 1 grade or 1 grade among the of the present invention 20 routine experimenters, judges that face cleaning product of the present invention has without any untoward reaction human body.
Experimental example 2-face cleaning product is to the removal effect of acarid
Prepared face cleaning product is on probation 36 male university students, and being divided into is 6 groups, every group 6 people, and promptly A group (blank group), B group (embodiment 7), C group (embodiment 8), D group (embodiment 9), E group (embodiment 10), F organize (Comparative Examples 4).Ginseng survey personnel and experimenter do not know the kind (double-blind method) of employed face cleaning product.
Experimental technique: before 6 groups of male university students use, after rising morning, put on the skin gently one time at face, then wet paper towel is detected acarid quantity, record respectively under 100 power microscopes with wet paper towel.6 groups of male university students use the corresponding face cleaning product of each group, every day 3 times.Continue after 15 days, with wet paper towel at face gently put one time after rising the 16th day morning, then wet paper towel detected acarid quantity respectively under 100 power microscopes, is recorded in microscopically and detects acarid quantity, record, the situation that detects of observing acarid.Effect is divided into 4 grades: 1 grade: wet paper towel does not have acarid and detects, 2 grades: wet paper towel has 1 acarid to detect 3 grades: wet paper towel has 2 acarids to detect 4 grades: wet paper towel has 3 or 3 above acarids to detect.Concrete data see Table 2
Table 2 is respectively organized experimenter's acarid situation
Above data declaration face cleaning product of the present invention has remarkable result to removing acarid; And the face cleaning product of litchi rind extract preparation does not possess the effect of removing acarid.
Experimental example 3-face cleaning product of the present invention is to antifungic action
1. experimenter's selection method:
Choose facial and auricle rear portion skin person 12 people that have the fungal infection.Male's 6 examples wherein, women's 6 examples.
2. using method:
Use group: the embodiment 6 an amount of affected parts of cleaning, adhered to using 15 days at every day 2 times.
The blank group: common face cleaning product cleans the affected part, every day 2 times, adheres to using 15 days.
3. in-service evaluation standard: adopt " TCM Dermatology disease diagnosis criterion of therapeutical effect ".Cure: skin lesion disappears fully, and wound surface heals fully, no longer includes new rash and occurs.Take a turn for the better: skin lesion heals more than 50%.Do not heal: skin lesion seemingly has new rash constantly to occur or healing skin lesion deficiency as before.Experimental results show that face cleaning product of the present invention has the broad-spectrum antifungal effect, deep fungal and part superficial fungi are had good killing and inhibitory action, and the present invention is used for the skin affected part, suppresses antibacterial, fungi growth and breeding, antipruritic, anti-allergic effects is played on the cleaning skin surface simultaneously.
4. use and the results are shown in Table 3
The caused skin infection curative effect statistics of 6 pairs of funguses of table 3 embodiment
Total routine number is cured the routine number routine number routine number of not healing that takes a turn for the better
Use organizes 6420
Blank group 6015
5 conclusions
Face cleaning product of the present invention has the broad-spectrum antifungal effect, and deep fungal and part superficial fungi are had good killing and inhibitory action.
Claims (6)
1. Semen Litchi extract is killed application in the face cleaning product of acarid and fungus in preparation, the preparation method of wherein said Semen Litchi extract is: 500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, and concentrated, spray drying promptly get Semen Litchi extract, water content is 3.5%, and described Semen Litchi extract weight ratio in face cleaning product is 0.1-25%.
2. according to the described application of claim 1, it is characterized in that described weight ratio is 0.1-15%.
3. according to the described application of claim 2, it is characterized in that described weight ratio is 1-10%.
4. according to the described application of claim 3, it is characterized in that described weight ratio is 1-5%.
5. the arbitrary described application of claim 1-4 is characterized in that described face cleaning product is facial milk cleanser or cleansing milk.
6. the arbitrary described application of claim 1-4 is characterized in that the preparation method of described face cleaning product is: with the dressing of described Semen Litchi extract adding face cleaning product, and stirring and evenly mixing, fill is promptly under the aseptic condition.
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| CN102764214A (en) * | 2012-07-04 | 2012-11-07 | 江苏天辅星光学材料有限公司 | Facial cleanser |
| CN102764220A (en) * | 2012-08-10 | 2012-11-07 | 启东市通洋机电有限公司 | Chinese medicinal herb facial cleanser |
| CN103735472B (en) * | 2014-02-11 | 2016-04-20 | 李振新 | Moisturizing cleansing milk that a kind of anemia of pregnant woman is suitable for and preparation method thereof |
| CN104434639A (en) * | 2014-11-14 | 2015-03-25 | 成都鹏翔生物科技有限公司 | Purely-natural facial cleanser capable of deeply decontaminating and controlling oil and preparation method thereof |
| CN104434638A (en) * | 2014-11-14 | 2015-03-25 | 成都鹏翔生物科技有限公司 | Chestnut tree extract-containing natural aftershave |
| CN104546608A (en) * | 2014-12-26 | 2015-04-29 | 刘三猫 | Composition for preparing facial cleaner and facial cleaner |
| CN108635255A (en) * | 2018-04-28 | 2018-10-12 | 广东巴松那生物科技有限公司 | It is a kind of to activate plant skin cream of Telomerase and preparation method thereof |
| CN108524358A (en) * | 2018-05-21 | 2018-09-14 | 李均辉 | A kind of hand cleanser and its preparation method and application of anti-inflammatory skin care |
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