CN1907257B - Application of litchi extract in preparation of teeth cleaning product with caries preventing and curing function - Google Patents
Application of litchi extract in preparation of teeth cleaning product with caries preventing and curing function Download PDFInfo
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Abstract
The invention belongs to the field of tooth health care products, and in particular a tooth cleaning product is provided which is prepared from the following lychee seed extract as the raw material. The tooth cleaning product has the functions of preventing dental caries, alleviating gingivitis, tooth root loosening, tooth haemorrhagia and dentalgia.
Description
[technical field]
The invention belongs to the dental care field, be specifically related to the application of Semen Litchi extract in the teeth cleaning product of preparation caries prevention.
[background technology]
Semen Litchi is the mature seed of Sapindaceae aiphyllium plant Fructus Litchi (Litchi chinsis Sonn.).Main product in Fujian, ground such as Guangdong, Guangxi.Pluck mature fruit summer, remove peel and meat aril, clean, dry.Give birth to or saline process usefulness.Time spent smashes.Semen Litchi acrid in the mouth, little hardship, temperature.Return liver, stomach through being mainly used in colicky, painful and swollen testis.This product catharsis of working hard has the merit of depressed liver-energy dispersing and QI regulating, promoting QI to circulate and dispersing the agglomeration of the pathogens, dispersing cold for relieving pain.Semen Litchi is controlled colic of cold type pain, can be equal to usefulness with Fructus Foeniculi, Fructus Evodiae, Semen Citri Reticulatae, as the hernia internal diabetes ball of " Beijing's Chinese traditional patent formulation selected works ".Control painful and swollen testis, many and Semen Citri Reticulatae, Fructus Toosendan are equal to usefulness.Semen Litchi also can be used for gastral cavilty pain of a specified duration, dysmenorrhea, puerperal abdonimal pain.It is logical that the hot row of this product hardship is let out temperature, and dispersing the stagnated liver-QI for regulating the stomach, regulating QI to relieve pain effect are arranged.The gastral cavilty pain of a specified duration of Semen Litchi treating the liver stagnation of QI knot, incoordination between the liver and stomach can be ground clothes into powder with the Radix Aucklandiae, looses as the Jing-Yue Complete Works litchi is fragrant, the dysmenorrhea and the puerperal abdonimal pain of the strongly fragrant qi depression to blood stasis for the treatment of the liver, can grind clothes into powder with perfume (or spice) limit, diffusing bitterly as " married woman's good recipe " stannum, or be equal to usefulness with Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Bupleuri.
Semen Litchi is Long Circle or oval, and is slightly flat, long 1.5～2.2cm, diameter 0.6～1.5cm.Surface brownish red or purple brown, glossy, slightly cave in and insertion waves.One end has the hilum of similar round or oval yellowish-brown, diameter 5～7mm.Matter is hard, cuts 2 of the visible plump cotyledons in back open with water infiltration, and orange-yellow or pale brown color is combined closely with kind of a skin.Feeble QI, it is little sweet, bitter, puckery to distinguish the flavor of.Big, full, bright person is good with grain.Its microscopical identification is: Semen Litchi (middle part) cross section: all plant the chrotoplast wall and be pale brown color.Plant the exocuticle cell extend radially of skin.About 10～15 row of parenchyma cell are arranged in it, and cell tangentially prolongs, the visible sparse Kong Wen that has.Brown oil cell similar round or Long Circle.The interrupted annular arrangement of vascular bundle.Decadent near the several layers of parenchyma cell of planting the skin epidermis, cell shrinkage, the gap is big.The endepidermis of planting skin is 1 row parenchyma cell, and is flat, different in size.Be full of starch grain in the parenchyma cell of cotyledon, and as seen have brown oil cell to be dispersed in.
American documentation literature US2004/0101508A1 discloses the purposes of extract aspect cosmetics and medicine of Fructus Litchi.Chinese patent literature (200410022559) provides Fructus Litchi extract and preparation method thereof, and this invention also provides the application of this Fructus Litchi extract in medicine, health food and cosmetics.But to the deep development of Semen Litchi extract, especially Semen Litchi extract does not have document to mention in the application of teeth cleaning product, does not have product open yet.Zheng Linying etc. reported Semen Litchi have suppress hbs antigen, effect (Chinese medicine journal, 1998 (5): 51-53) such as blood sugar lowering, enhancing mouse liver albumen and RNA be synthetic; (Chinese Journal of New Drugs, 2000 (1): 14-16) reported that also Semen Litchi has blood lipid regulation and antioxidation such as Pan Jing clanging or clanking sound except above effect.
[summary of the invention]
The objective of the invention is to turns waste into wealth annual about 500,000 tons Semen Litchi, and development and use are used to prepare teeth cleaning product, and this teeth cleaning product has caries prevention and alleviates the effect of gingivitis, tooth root loosening, dental root hemorrhage and toothache.
Another object of the present invention is to provide the teeth cleaning product preparation method.
Teeth cleaning product of the present invention contains Semen Litchi extract.
Teeth cleaning product of the present invention contains Semen Litchi extract and teeth cleaning product adjuvant.
Above-mentioned teeth cleaning product comprises toothpaste or dentifrice.
Above-mentioned teeth cleaning product, the Semen Litchi extract weight ratio in teeth cleaning product is 0.5-30%, preferred 0.5-20%, most preferably 1-10%.
Semen Litchi extract among the present invention also can adopt commercially available product (existing at present Semen Litchi extract is sold), can also obtain by other organic solvents or water extraction.
Above-mentioned teeth cleaning product can also add one or more in Margarita, Margarita micropowder, Folium Menthae extract, Aloe extract, Radix Zanthoxyli extract, Radix Notoginseng extract, Semen Vitis viniferae extract, vitamin C and the sodium chloride.
The preparation method of teeth cleaning product of the present invention is: water and alcoholic acid mixed solvent extraction were 2-3 time after Semen Litchi was pulverized, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrated after drying promptly gets Semen Litchi extract, with Semen Litchi extract add the dressing of teeth cleaning product, stirring and evenly mixing, packing promptly.
The water content of the Semen Litchi extract in the preparation method of above-mentioned teeth cleaning product is controlled at 2.5-3.5%.
Another object of the present invention is to provide the application of Semen Litchi extract in the teeth cleaning product of preparation caries prevention, the percentage by weight of wherein said Semen Litchi extract in teeth cleaning product is 1%, and described Semen Litchi extract adopts following method preparation: 500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrated, spray drying, promptly get Semen Litchi extract, the water content of Semen Litchi extract is 3.1%.
In the above-mentioned application, described teeth cleaning product can also add one or more in Margarita, Folium Menthae extract, Aloe extract, Radix Zanthoxyli extract, Radix Notoginseng extract, Semen Vitis viniferae extract, vitamin C and the sodium chloride.
Because Guangdong and Guangxi Provinces, Fujian and Taiwan Fructus Litchi output are huge, many mountain areas, the Fructus Litchi place of production and hills, have inconvenient traffic, and Fructus Litchi requires very harsh to storage and traffic condition, often occur going mouldy owing to Fructus Litchi can not be caused by place of production outward transport in time, at this moment pulp and Fructus Litchi kind skin have not all had value, Semen Litchi can also add in the teeth cleaning product by drying, sterilization and pulverizing back or processing extraction only, turn waste into wealth, produce bigger economic worth, also can increase farmers' income for the Fructus Litchi grower retrieves a loss.
China's Fructus Litchi output is huge, and Fructus Litchi output was about 1,500,000 tons in 2005, and resource is very abundant, because the difference of Fructus Litchi kind accounts for Fructus Litchi gross weight 1/3 with Semen Litchi and calculates, annual China just has 500,000 tons of Semen Litchi resources to develop.From the raw material as teeth cleaning product, Semen Litchi has than the better advantage of Fructus Litchi, says that from content of effective difference of them is little, but because Fructus Litchi is in the fruit outside, contacts with air, and active component is oxidized easily; And Fructus Litchi is as a kind of fruit, by people edible after, peel is difficult to collect, the gross weight ratio that Fructus Litchi accounts for litchi fruits is little; And Semen Litchi weight is big, is easy to collect after eating; Directly Semen Litchi is taken out when also having businessman to produce canned litchi, be more convenient for the collection of Semen Litchi like this.
Fructus Litchi is since ancient times owing to the well-known phrase of " rides the human society imperial concubine laughs at; nobody knows Fructus Litchi " fires one's imagination, become a kind of and beautiful fruit of becoming attached to, Semen Litchi really is used to beautify people's life, also be not used in preparation toothpaste or dentifrice but also have no talent at present.
The present invention verifies the raw material of Semen Litchi extract as a kind of teeth cleaning product by experiment, has the incomparable effect of other teeth cleaning product, especially going caries prevention and alleviating gingivitis, tooth root loosening, dental root hemorrhage and toothache aspect have significant improvement effect, in addition, Semen Litchi extract also has favorable compatibility, also can make teeth cleaning product by compatibility with other plant or plant extract, also have caries prevention and alleviate gingivitis, tooth root loosening, the effect of dental root hemorrhage and toothache effect, wherein the effect of Semen Litchi extract is indispensable.
[specific embodiment]
Following embodiment further describes the present invention, but described embodiment only is used to illustrate the present invention rather than restriction the present invention.
The preparation of embodiment 1-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 1-2 hour at every turn 2-3 time, the temperature of extracting is 55-65 ℃, concentrates the back under 70 ℃ of conditions, vacuum drying oven 6 hours, promptly get Semen Litchi extract, water content is 2.8%.
The preparation of embodiment 2-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and ethanol and being 1: 3 are got 1-2 hour at every turn 2-3 time, the temperature of extracting is 55-70 ℃, concentrates the back under 80 ℃ of conditions, vacuum drying oven 5 hours, promptly get Semen Litchi extract, water content is 2.9%.
The preparation of embodiment 3-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 2-3 time, and each 1-2 hour, the temperature of extraction was 55-70 ℃, and concentrated, spray drying promptly get Semen Litchi extract, and water content is 3.1%.
The preparation of embodiment 4-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 3 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrate, after the spray drying under 75 ℃ of conditions, vacuum drying oven 5 hours promptly gets Semen Litchi extract, and water content is 3.0%.
The preparation of embodiment 5-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and ethyl acetate and being 1: 3 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrate, after the spray drying under 50 ℃ of conditions, vacuum drying oven 8 hours promptly gets Semen Litchi extract, and water content is 2.5%.
The preparation of embodiment 6-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 20 are got 2-3 time, and each 1-2 hour, the temperature of extraction was 55-70 ℃, and concentrated, spray drying promptly get Semen Litchi extract, and water content is 3.5%.
The preparation of embodiment 7-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and acetone and being 20: 1 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrate, after the spray drying under 50 ℃ of conditions, vacuum drying oven 5 hours promptly gets Semen Litchi extract, and water content is 3.0%.
The preparation of embodiment 8-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and ethanol and being 1: 20 are got 2-3 time, and each 1-2 hour, the temperature of extraction was 40-70 ℃, and concentrated, spray drying promptly get Semen Litchi extract, and water content is 2.7%.
The preparation of embodiment 9-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and ethanol and being 20: 1 are got 2-3 time, each 1-2 hour, the temperature of extracting is 40-70 ℃, concentrate, after the spray drying under 50 ℃ of conditions, vacuum drying oven 5 hours promptly gets Semen Litchi extract, and water content is 3.5%.
The preparation of embodiment 10-Semen Litchi extract
500 gram Semen Litchis, mixed solvent 3 ascending of pulverizing the two weight ratio of back water and ethyl acetate and being 1: 5 are got 2-3 time, each 1-2 hour, the temperature of extracting is 40-70 ℃, concentrate, after the spray drying under 60 ℃ of conditions, vacuum drying oven 8 hours promptly gets Semen Litchi extract, and water content is 3.1%.
The preparation of embodiment 11-Semen Litchi extract
500 gram Semen Litchis are pulverized the back and are got 2-3 time with acetone 2.5 ascending, and each 1-2 hour, the temperature of extraction was 40-70 ℃, and concentrated, spray drying promptly get Semen Litchi extract, and water content is 2.7%.
The preparation of embodiment 12-Semen Litchi extract
500 gram Semen Litchis are pulverized the back and are got 2-3 time with ethyl acetate 3 ascending, and 1-2 hour at every turn, the temperature of extraction was 40-70 ℃, and under 50 ℃ of conditions, vacuum drying oven 5 hours promptly gets Semen Litchi extract after concentrated, the spray drying, and water content is 3.2%.
The preparation of embodiment 13-Semen Litchi extract
500 gram Semen Litchis are pulverized the back and are got 2-3 time with ethanol 3 ascending, and 1-2 hour at every turn, the temperature of extraction was 40-70 ℃, and under 50 ℃ of conditions, vacuum drying oven 8 hours promptly gets Semen Litchi extract after concentrated, the spray drying, and water content is 3.0%.
Embodiment 14-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract (embodiment 1) of 1g, behind the irradiation sterilization, after adding 550g dimethyl-silicon, 200g calcium carbonate, 100g glycerol, 130g propylene glycol, 5g retinoic acid, 10g sodium lauryl sulphate, 3.5g carboxymethyl cellulose and 0.5g methyl parahydroxybenzoate, the high-speed stirred mixing, obtain the 1000g creme with pre-hair jelly water law processing, fill is 10 packings, promptly.
Embodiment 15-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract (embodiment 2) of 50g, behind the irradiation sterilization, after adding 45g Radix Zanthoxyli extract, 5000g calcium carbonate, 2200g carboxymethyl cellulose, polyvinyl alcohol 300g, 5g potassium nitrate and 2400g glycerol, the high-speed stirred mixing, obtain the 10000g creme with pre-hair jelly water law processing, fill is 200 packings, promptly.
Embodiment 16-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract (embodiment 3) of 100g, behind the irradiation sterilization, after adding 3000g calcium carbonate, 2800g silicon dioxide, 590g sorbitol, 5g dichloroacetic acid, 2000g glycerol, 1500g ethyl cellulose and 5g sodium monofluorophosphate, the high-speed stirred mixing, obtain the 10000g creme with pre-hair jelly water law processing, fill is 200 packings, promptly.
Embodiment 17-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract (embodiment 4) of 500g, behind the irradiation sterilization, after adding 1600g calcium carbonate, 2500g silicon dioxide, 3600g carboxymethyl cellulose, 1290g glycerol, sodium fluoride 1g, sodium monofluorophosphate 4g, 1000g pure water and 5g sodium benzoate, the high-speed stirred mixing, obtain the 10000g creme with pre-hair jelly water law processing, fill is 100 packings, promptly.
Embodiment 18-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract of 1000g, behind the irradiation sterilization, after adding 2500g calcium carbonate, 2500g calcium hydrogen phosphate, 100g silicon dioxide, 300g POLYPROPYLENE GLYCOL, 1500g glycerol, 2000g pure water, 50g sorbitol, 5g Folium Menthae extract, 40g potassium nitrate, 3g HANSHENGJIAO, 1g sodium monofluorophosphate, 1g sodium fluoride and 5g essence, the high-speed stirred mixing, obtain the 10000g creme with pre-hair jelly water law processing, fill is 100 packings, promptly.
Embodiment 19-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract (embodiment 1) of 150g, behind the irradiation sterilization, after adding 400g calcium carbonate, 180g silicon dioxide, 10g aluminium hydroxide, 150g sorbitol, 0.1g sodium fluoride, 4.9g vitamin C, 0.5g sodium lauryl sulphate, 100g pure water and 4.5g potassium nitrate, high-speed stirred, add the 0.5g methyl parahydroxybenzoate, stirring and evenly mixing obtains 1000g creme, fill with the processing of pre-hair jelly water law and is 10 and packs, promptly.
Embodiment 20-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract (embodiment 1) of 200g, behind the irradiation sterilization, after adding 300g calcium carbonate, 230g silicon dioxide, 10g Semen Vitis viniferae extract, 150g sorbitol, 0.1g sodium fluoride, 4.9g retinoic acid, 0.5g sodium lauryl sulphate, 100g pure water and 4.5g potassium nitrate, high-speed stirred, add the 0.5g methyl parahydroxybenzoate, stirring and evenly mixing obtains 1000g creme, fill with the processing of pre-hair jelly water law and is 10 and packs, promptly.
Embodiment 21-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract of 300g, behind the irradiation sterilization, after adding 300g calcium carbonate, 5g Margarita micropowder, 45g sorbitol, 4.5g dichloroacetic acid, 200g glycerol, 150g ethyl cellulose and 0.5g sodium monofluorophosphate, the high-speed stirred mixing, obtain the 1000g creme with pre-hair jelly water law processing, fill is 10 packings, promptly.
Embodiment 22-contains the preparation of Semen Litchi extract toothpaste
Get the Semen Litchi extract of 10g, behind the irradiation sterilization, after adding 440g calcium carbonate, 230g silicon dioxide, 10g vitamin C, 150g sorbitol, 0.1g sodium fluoride, 4.9g retinoic acid, 0.5g sodium lauryl sulphate, 100g pure water and 4.5g potassium nitrate, high-speed stirred, after adding the 0.5g methyl parahydroxybenzoate, stirring and evenly mixing obtains 1000g creme, fill with the processing of pre-hair jelly water law and is 10 and packs, promptly.
Embodiment 23-contains the preparation of Semen Litchi extract dentifrice
Get the Semen Litchi extract (embodiment 4) of 10g, behind the irradiation sterilization, after adding 890g calcium carbonate, 5g Folium Menthae extract, 45g hydroxy-methylbenzene dibutyl ester, 4.5g dichloroacetic acid, 50g glycerol, stirring and evenly mixing, high-speed stirred adds the 0.5g methyl parahydroxybenzoate, stirring and evenly mixing behind 200 mesh sieves excessively, be packed as 40 packings, promptly.
Embodiment 24-contains the preparation of Semen Litchi extract dentifrice
Get the Semen Litchi extract (embodiment 1) of 1500g, behind the irradiation sterilization, after adding 6000g calcium carbonate, 1800g silicon dioxide, 100g aluminium hydroxide, 500g sorbitol, 5g sodium fluoride, 50g vitamin C, 5g sodium lauryl sulphate and 40g potassium nitrate, high-speed stirred, cross 200 mesh sieves, stirring and evenly mixing is packed as 40 packings, promptly.
Experimental example 1
Object of study: the school junior middle school student, wherein male 16 people, women 18 people.
Make the method for getting rid of: get toothpaste of the present invention (embodiment 16) and brush teeth, kept 3 minutes at every turn, every day, 3 (three after the meal) logotypes were 14 days.
Result of the test: after brushing teeth, oral sensation is pressed from both sides clearly, and lasting is lasting, and none routine kainogenesis dental caries and toothache.
This shows that the present invention can caries prevention and toothache.
Experimental example 2
Object of study: gingivitis patients 32 people, wherein male 18 people, women 14 people.
Using method: brush teeth with toothpaste of the present invention (embodiment 17), kept 3 minutes at every turn, every day 3 times, (three reach after the meal sleep before each 1 time) logotype was 10.
Result of the test: 24 people that fully recover, transference cure accounts for 75%; Produce effects 8 people, symptom obviously alleviates, and accounts for 25%; Invalid 0 people.
This shows that the present invention can be alleviated gingivitis.
Experimental example 3
Kindergarten is selected 102 5-6 year children, is divided into two groups to test, and every group 51 people brushes teeth with toothpaste of the present invention (embodiment 18) for one group, uses common children's toothpaste for one group.On inspection, these children caries all between 0-3, are learned by statistics and are handled P＞0.05 no significant difference before experiment.After 12 months, remake the dental caries check, calculate each children caries increased numbers.
Table 1 dental caries increased numbers contrasting data
| The dental caries increased numbers | Teeth cleaning product of the present invention | Common children's toothpaste |
| 0 | 33 | 18 |
| 1 | 15 | 12 |
| 2 | 2 | 13 |
| 3 | 1 | 7 |
| 4 | 0 | 1 |
| 5 | 0 | 0 |
| Add up to | 22 | 63 |
From last table as seen, observation group's children caries increased numbers is 0.43, and matched group is 1.24, learns by statistics and handles, and matched group is to be higher than test group (P＜0.01) significantly.
This shows that teeth cleaning product of the present invention has certain anti-caries, mothproof effect.
Experimental example 4
Typical case:
Case a: the man, 55 years old, suffer from gingivitis, gingival swelling and pain, often hemorrhage, use toothpaste of the present invention (embodiment 21) to brush teeth, every day 3 times, each 3 minutes, after 15 days, the red and swollen disappearance, no longer hemorrhage, continue to use after one month and cure, do not see recurrence half a year.
Case b: woman 38 years old, toothache, tooth were diagnosed as dentin hypersensitiveness and tooth wine inflammation with hemorrhage 8 years through examination in hospital, taking the anti-microbial type Drug therapy does not have obvious curative effects, uses toothpaste of the present invention (embodiment 22) to brush teeth every day 3 times, each 3 minutes, after one week, tooth is followed no longer hemorrhage, pain relief, continue to make articles for use after 2 weeks, pain disappears, and continues to use 2 weeks to consolidate curative effect, does not see recurrence half a year.
Case c: the woman, 27 years old, suffer from toothache 8 years, send out when the time heals, over nearly two months, outbreak again and again, pain is periodontitis and tooth root loosening through hospital diagnosis unbearably, injection antimicrobial drug and take the antibiotic medicine and all do not have produce effects, use dentifrice of the present invention (embodiment 24) to brush teeth, every day 3 times, each 3 minutes, pain relief after the week, continue to make three all pain to disappear, continue to use five all backs teeth loosening.
Case d, man, 51 years old, toothache, red swelling of gingiva were had a surplus in hemorrhage skilful year, through examination in hospital, were diagnosed as periodontitis, though through how tame hospital and Chinese traditional treatment, curative effect is very little, use dentifrice of the present invention (embodiment 24) to brush teeth, every day 3 times, each 3 minutes, after two weeks, pain, hemorrhage, red and swollen, the basic disappearance, after continuing to use for two weeks, the above-mentioned symptom complete obiteration.
This shows that the present invention can all have mitigation to periodontitis, toothache, tooth root loosening, dental root hemorrhage.
Claims (2)
1. the application of Semen Litchi extract in the teeth cleaning product of preparation caries prevention, the percentage by weight of wherein said Semen Litchi extract in teeth cleaning product is 1%, and described Semen Litchi extract adopts following method preparation: 500 gram Semen Litchis, mixed solvent 2.5 ascending of pulverizing the two weight ratio of back water and acetone and being 1: 2 are got 2-3 time, each 1-2 hour, the temperature of extracting is 55-70 ℃, concentrated, spray drying, promptly get Semen Litchi extract, the water content of Semen Litchi extract is 3.1%.
2. according to the described application of claim 1, it is characterized in that described teeth cleaning product can also add one or more in Margarita, Folium Menthae extract, Aloe extract, Radix Zanthoxyli extract, Radix Notoginseng extract, Semen Vitis viniferae extract, vitamin C and the sodium chloride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006101116689A CN1907257B (en) | 2006-08-22 | 2006-08-22 | Application of litchi extract in preparation of teeth cleaning product with caries preventing and curing function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006101116689A CN1907257B (en) | 2006-08-22 | 2006-08-22 | Application of litchi extract in preparation of teeth cleaning product with caries preventing and curing function |
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| CN1907257B true CN1907257B (en) | 2010-04-07 |
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| CN103536497B (en) * | 2013-10-30 | 2015-08-26 | 昆明理工大学 | A kind of Traditional Chinese medicinal compound collutory and preparation method thereof |
| CN108524714A (en) * | 2018-07-10 | 2018-09-14 | 李�杰 | Alleviate the buccal tablets for symptom of having a toothache |
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