CN103893074A - Toothpaste containing traditional Chinese medicine plant essences and preparation method of toothpaste - Google Patents
Toothpaste containing traditional Chinese medicine plant essences and preparation method of toothpaste Download PDFInfo
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Abstract
The invention discloses toothpaste containing traditional Chinese medicine plant essences and a preparation method of the toothpaste, wherein the toothpaste disclosed by the invention comprises the following components in parts by weight: 40-55 parts of gypsum powder, 10-20 parts of purified water, 5-20 parts of plant essence extractives, 1-10 parts of a corrigent, 1-10 parts of an excipient, and 5-15 parts of accessories; and the plant essence extractives comprises the following components in parts by weight: 1-10 parts of honeysuckle extractive, 1-10 parts of dandelion extractive, 0.5-5 parts of folium ginkgo extractive, 0.5-5 parts of lucid ganoderma extractive, and 1-10 parts of pseudo-ginseng ultrafine powder. The preparation method of the toothpaste disclosed by the invention comprises the following steps of: mixing the plant essence extractives in a pre-mixer, then, after respectively pre-mixing oil-soluble materials and water-soluble materials in other components, adding into a vacuum toothpaste making machine to make toothpaste, wherein the vacuum degree is minus 0.085 to minus 0.095 MPa; the density of the toothpaste material is more than 1.58 g/cm<3>; the temperature is 25-45 DEG C; and the pH is 9; and finally, filling and tabulating the toothpaste body, and obtaining the toothpaste.
Description
Technical field
The invention belongs to Chinese medicine daily necessities field, more particularly to a kind of toothpaste succinct containing Chinese medicinal plant and preparation method thereof.
Background technology
With the development of science and technology, human health problems increasingly become problem of concern, more and more wider with the scope of diet, and our oral health issue is increasingly severe.Illness finds its way in by the mouth, and the species of people's diet of modern society is more and more miscellaneous, and the time of diet is more and more changeable, and tooth is also a most important pass as the first pass of our diet links, is faced with increasingly stern challenge.In recent years, the dentistry of each hospital turns into popular section office, the epidemic disease having in terms of tooth of city crowd more or less, carious tooth, decayed tooth, anaphylaxis dentine, gingivitis, periodontitis etc. have deeply had influence on our daily life, among many people just endure the worries that can't have dinner because having a toothache to the fullest extent and decocted.
In recent years by Chinese herbal medicine effect type toothpaste obtained by Chinese herbal medicine extract or crude drug addition toothpaste increasingly by the accreditation and purchase of consumers in general.This kind of toothpaste not only has the function of general toothpaste, also there are unique anti-caries, effect of inhibiting bacteria and diminishing inflammation, analgesic hemostatic, what is played the role of also prevents hemodia with good, and existing multiple domestic brands are in commercial type, such as Radix zanthoxyli, Luclean, pseudo-ginseng, Yunnan Baiyao etc., external Colgate-Palmolive, Crest etc. are also proposed the draft concept toothpaste of oneself one after another immediately following trend.With the development of holistic science, the understanding to Chinese herbal medicine and Chinese herbal medicine extract is constantly deepened and correlative study is constantly in progress, and the market proportion shared by Chinese herbal toothpaste will be increasing.
But the comparison of ingredients containing Chinese herbal medicine is single in Traditional-Chinese-medicine-type toothpaste in the market, although certain medicinal effects can be played, but certain effect can just be reached by needing to use for a long time, therefore a kind of more preferable Chinese herbal toothpaste of the medicinal effects containing composite Chinese herbal composition of exploitation is needed, the need for meeting market.
The content of the invention
Invent the technical problem solved：It is an object of the invention to a kind of toothpaste succinct containing Chinese medicinal plant and preparation method thereof is provided to solve above the deficiencies in the prior art.
Technical scheme
A kind of toothpaste succinct containing Chinese medicinal plant, includes by weight part：40-55 parts of land plaster, 10-20 parts of purified water, plant 5-20 parts of extract of essence, 1-10 parts of flavouring, 1-10 parts of excipient, 5-15 parts of auxiliary material；The wherein succinct extract of plant includes 1-10 parts of Honegsukle flower P.E, 1-10 parts of dandelion extract, 0.5-5 parts of ginkgo biloba p.e, 0.5-5 parts of Ganodenna Lucidum P.E, 1-10 parts of pseudo-ginseng superfine powder；Wherein auxiliary material is one kind in guar gum, waterglass, sorbierite, propane diols, silica, Nepal's methyl esters or Nepal's propyl ester.
The described toothpaste succinct containing Chinese medicinal plant, land plaster can be 325 mesh.
The described toothpaste succinct containing Chinese medicinal plant, flavouring can be saccharin, menthol or Mint Essence.
The described toothpaste succinct containing Chinese medicinal plant, excipient can be carboxymethyl cellulose or sodium alginate.
The described toothpaste succinct containing Chinese medicinal plant, the content of Honegsukle flower P.E Content of Chlorogenic Acid can be 5%.
The described toothpaste succinct containing Chinese medicinal plant, the withdrawal ratio of dandelion extract can be 10:1.
The described toothpaste succinct containing Chinese medicinal plant, the withdrawal ratio of Ganodenna Lucidum P.E can be 20:1.
The described toothpaste succinct containing Chinese medicinal plant, pseudo-ginseng superfine powder particle diameter can be 100-200 mesh.
The preparation method of the toothpaste succinct containing Chinese medicinal plant described in more than one any one, step is as follows：
（1）The succinct extract of plant is placed in premixed device and mixed, mixing condition is normal temperature, 20r/min, incorporation time 3min；
（2）Other components oil-soluble material is premixed respectively with Water-solubility Material according to formula rate, cream to be made is used；
（3）Material after premix is added in vacuum Manufacturing medicine extract machine and carries out cream processed, cream condition processed is vacuum -0.085~-0.095MPa, creme density is more than 1.58g/cm3, 25-45 DEG C of temperature, pH9；
（4）Lotion after cream processed is subjected to filling and tubulation, finished toothpaste is obtained.
Beneficial effect
The toothpaste succinct containing Chinese medicinal plant that the present invention is provided is a kind of Chinese herbal medicine feature toothpaste that with the addition of the succinct extract of plant.With Chinese traditional herbs toothpaste except that plant essence toothpaste is played a role jointly by multiple functional components, the Chinese herbal toothpaste single compared to tradition, the effect with more preferable inhibiting bacteria and diminishing inflammation hemostasis and pain-relieving.Its main component has：Honegsukle flower P.E, dandelion extract, ginkgo biloba p.e, Ganodenna Lucidum P.E and pseudo-ginseng superfine powder.According to《Pharmacopoeia of People's Republic of China》（Version one in 2010）Record, a few taste medicinal materials have following functions respectively：
1st, pseudo-ginseng, dissipate stasis of blood hemostasis, detumescence ding-tong for spitting blood, is spitted blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, traumatism and bleeding, chest and abdomen shouting pain, tumbling and swelling.
2nd, ganoderma lucidum, invigorating qi for tranquilization is relieving cough and asthma, for having no peace of mind, and palpitaition of having a sleepless night, deficiency syndrome of the lung cough and asthma, consumptive disease is losed heart, do not feel like eating.
3rd, ginkgo leaf, it is promoting blood circulation and removing blood stasis, remove obstruction in channels to relieve pain, astringe the lung and relieving asthma, change turbid lipid-loweringing, network, obstruction of qi in the chest worry, hemiplegia, deficiency syndrome of the lung cough and asthma, hyperlipidemia are hindered for extravasated blood.
4th, dandelion, clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia, for treating pyogenic infections from tumour or sore, acute mastitis scrofula, hot eyes pharyngalgia, lung carbuncle acute appendicitis, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.
5th, honeysuckle, clearing heat and detoxicating, dispelling wind and heat from the body, for carbuncle swells furunculosis, larynx numbness, erysipelas, toxic-heat and blood stasis, anemopyretic cold, warm morbidity.
Gomi herbs or extract are cooperateed with mutually together, both effect of pseudo-ginseng detumescence hemostasis can have been expanded, dandelion and the clearing heat and detoxicating effect of honeysuckle can be played simultaneously again, the dredging collateral effect calmed the nerves with ginkgo leaf of ganoderma lucidum is also utilized well in we, and user's oral problem can further be alleviated by coordinating effect of other three tastes medicinal materials.
Universal thinks that herbal medicine efficacy is the result acted synergistically by each prescription component, especially in Chinese medicine compound prescription.Plant essence in the toothpaste succinct containing Chinese medicinal plant that the present invention is provided is mixed by traditional Chinese medicine of the five flavours material or extract, its main component has flavonoids, alkaloids, terpene, polysaccharide etc., component can produce synergy again while respective effect is played, and expand mutual effect.Wherein Flavonoid substances and terpene substances antibacterial, it is antiviral in terms of there is good action, and drug resistance and adverse reaction will not be produced.Plant essence in the toothpaste succinct containing Chinese medicinal plant that the present invention is provided with cell membrane and cell membrane system by acting, cell permeability and osmotic pressure is forced to produce change, so that the institutional framework of bacterial cell itself is degraded, or cellular genetic material is undergone mutation, or make it that the metabolic function of cell in itself gets muddled and causes cell loss.Flavones ingredient wherein in notoginsenoside constituents and honeysuckle has good anastalsis, it is applied in numerous Chinese medicine preparations, flavones ingredient in ginkgo biloba p.e plays the role of anti-inflammation, dandelion is conducive to clearing heat and removing internal heat, alleviates oral inflammation, the generation of pre- preventing parodontitis etc., triterpenes components in ganoderma lucidum have good bioactivity, can pre- anti-caries, make oral cavity refreshing, remove effect of bacterial plaque etc..The toothpaste prepared by this formula, have the advantages that the pure and fresh effect of mouthfeel is definite, and the selected Chinese medicine preparation of the present invention is extract or superfine powder, embodies the modernization practical application of traditional Chinese medicine, more beneficial to the performance of effect, while being also beneficial to the preparation of lotion of toothpaste.
Chinese medicinal toothpaste conventional at present is generally folk prescription into agent, with the addition of herbal mixture extraction elite in the toothpaste of this patent, compared with traditional Chinese medicine toothpaste, every Chinese medical extract or Chinese medicine preparation in we play synergy so that more notable with curative effect.The toothpaste of this patent is used in vacuum cream simultaneously, and a step is into cream method.Compared with traditional interval legal system cream and substep legal system cream, more preferable program control operation can be achieved, operating efficiency is greatly improved, meanwhile, the method make it that spices ease consumption cost the most valuable in toothpaste is substantially reduced, and effectively reduces the loss of cost.
The overall step for the toothpaste preparation method succinct containing Chinese medicinal plant that the present invention is provided is completed under vacuum conditions, and obtained toothpaste craft sanitary is up to standard.Technique simplifies, and required plant area is small, is easy to modern management, is a route for being well suited for middle-size and small-size toothpaste technological updating of enterprises.
Brief description of the drawings
Fig. 1 is the preparation technology flow chart of the toothpaste succinct containing Chinese medicinal plant of the present invention.
Embodiment
Preparation technology flow containing the succinct toothpaste of Chinese medicinal plant in following examples is as shown in figure 1, the land plaster particle diameter used in preparation process is 325 mesh.
Embodiment 1
A kind of toothpaste succinct containing Chinese medicinal plant, its formula is as follows：
Wherein plant essence extraction composition formula is as follows：
Honegsukle flower P.E（5% chlorogenic acid content）1.65 parts；Dandelion extract（Crude drug is 10 with extract withdrawal ratio:1）1.65 parts；Ginkgo biloba p.e（Pharmacopeia annex）0.5 part；Ganodenna Lucidum P.E（Crude drug is 20 with extract withdrawal ratio:1）0.5 part；Pseudo-ginseng superfine powder（100 mesh）1 part
The above-described toothpaste succinct containing Chinese medicinal plant is prepared in accordance with the following methods：
（1）Plant essence is placed in premixed device and mixed, mixing condition is normal temperature, 20r/min, 3min.
（2）According to formula ingredient proportion, by land plaster, silica and other powders are mixed after being measured with electronic weighbridge, standby in premix dry powder batch can；It is according to formula ingredient proportion, oil-soluble constitents are mutually pre- mixed, obtain oil phase；According to formula ingredient proportion, water-soluble co-solvents are mixed in water in advance, and add quantitative sorbierite, aqueous phase is obtained.
（3）The scraper of first trial operation vacuum Manufacturing medicine extract machine under vacuum conditions, after without exception, starts vavuum pump, injects water, fed intake when vacuum reaches -0.085MPa, advanced aqueous phase starts scraper, then enter oil phase glue, start stirring, control glue charging rate, prevent foaming knot grain.When vacuum reaches -0.085MPa after charging is finished, colloid mill is opened 5 minutes, stop mill 3 minutes, be then turned on shutting down after 5 minutes, stand.
（4）Open and stirring is then turned on after scraper, treat that vacuum reaches -0.095MPa, put into powder, plant is succinct while putting into, and control charging rate prevents that foaming from overflowing.Treat that charging finishes vacuum and reaches that cream face is steady in -0.095MPa reactors, opens colloid mill 5 minutes, stop mill 3 minutes, then open homogeneous 5 minutes, then stop mill 3 minutes, then open homogeneous 5 minutes, put into the essence of formula rate.Homogeneous is opened after vacuum reaches -0.095MPa 5-10 minutes, shut down, cream processed is finished.Cream condition processed is vacuum -0.095MPa, creme density 1.62g/cm3, 25 DEG C, pH9 or so.
（5）Lotion progress after cream processed is filling, tubulation is carried out using PAP, finished toothpaste is obtained.
Embodiment 2
A kind of toothpaste succinct containing Chinese medicinal plant, its formula is as follows：
Wherein plant essence extraction composition formula is as follows：
Honegsukle flower P.E（5% chlorogenic acid content）1 part；Dandelion extract（Crude drug is 10 with extract withdrawal ratio:1）10 parts；Ginkgo biloba p.e（Pharmacopeia annex）2 parts；Ganodenna Lucidum P.E（Crude drug is 20 with extract withdrawal ratio:1）3 parts；Pseudo-ginseng superfine powder（150 mesh）5 parts
The above-described toothpaste succinct containing Chinese medicinal plant is prepared in accordance with the following methods：
（1）Plant essence is placed in premixed device and mixed, mixing condition is normal temperature, 20r/min, 3min.
（2）According to formula ingredient proportion, by land plaster, silica and other powders are mixed after being measured with electronic weighbridge, standby in premix dry powder batch can；It is according to formula ingredient proportion, oil-soluble constitents are mutually pre- mixed, obtain oil phase；According to formula ingredient proportion, water-soluble co-solvents are mixed in water in advance, and add quantitative sorbierite, aqueous phase is obtained.
（3）The scraper of first trial operation vacuum Manufacturing medicine extract machine under vacuum conditions, after without exception, starts vavuum pump, injects water, fed intake when vacuum reaches -0.090MPa, advanced aqueous phase starts scraper, then enter oil phase glue, start stirring, control glue charging rate, prevent foaming knot grain.When vacuum reaches -0.090MPa after charging is finished, colloid mill is opened 8 minutes, stop mill 4 minutes, be then turned on shutting down after 5 minutes, stand.
（4）Open and stirring is then turned on after scraper, treat that vacuum reaches -0.090MPa, put into powder, plant is succinct while putting into, and control charging rate prevents that foaming from overflowing.Treat that charging finishes vacuum and reaches that cream face is steady in -0.090MPa reactors, opens colloid mill 5 minutes, stop mill 5 minutes, then open homogeneous 6 minutes, then stop mill 4 minutes, then open homogeneous 5 minutes, put into the essence of formula rate.Homogeneous is opened after vacuum reaches -0.090MPa 8 minutes, shut down, cream processed is finished；Cream condition processed is creme density 2.03g/cm3, 30 DEG C, pH9 or so.
（5）Lotion progress after cream processed is filling, tubulation is carried out using PAP, finished toothpaste is obtained.
Embodiment 3
A kind of toothpaste succinct containing Chinese medicinal plant, its formula is as follows：
Wherein plant essence extraction composition formula is as follows：
Honegsukle flower P.E（5% chlorogenic acid content）10 parts；Dandelion extract（Crude drug is 10 with extract withdrawal ratio:1）1 part；Ginkgo biloba p.e（Pharmacopeia annex）5 parts；Ganodenna Lucidum P.E（Crude drug is 20 with extract withdrawal ratio:1）5 parts；Pseudo-ginseng superfine powder（200 mesh）10 parts
The above-described toothpaste succinct containing Chinese medicinal plant is prepared in accordance with the following methods：
（1）Plant essence is placed in premixed device and mixed, mixing condition is normal temperature, 20r/min, 3min.
（2）According to formula ingredient proportion, by land plaster, silica and other powders are mixed after being measured with electronic weighbridge, standby in premix dry powder batch can；It is according to formula ingredient proportion, oil-soluble constitents are mutually pre- mixed, obtain oil phase；According to formula ingredient proportion, water-soluble co-solvents are mixed in water in advance, and add quantitative sorbierite, aqueous phase is obtained.
（3）The scraper of first trial operation vacuum Manufacturing medicine extract machine under vacuum conditions, after without exception, starts vavuum pump, injects water, fed intake when vacuum reaches -0.092MPa, advanced aqueous phase starts scraper, then enter oil phase glue, start stirring, control glue charging rate, prevent foaming knot grain.When vacuum reaches -0.092MPa after charging is finished, colloid mill is opened 10 minutes, stop mill 5 minutes, be then turned on shutting down after 10 minutes, stand.
（4）Open and stirring is then turned on after scraper, treat that vacuum reaches -0.092MPa, put into powder, plant is succinct while putting into, and control charging rate prevents that foaming from overflowing.Treat that charging finishes vacuum and reaches that cream face is steady in -0.092MPa reactors, opens colloid mill 5 minutes, stop mill 5 minutes, then open homogeneous 7 minutes, then stop mill 4 minutes, then open homogeneous 10 minutes, put into the essence of formula rate.Homogeneous is opened after vacuum reaches -0.092MPa 10 minutes, shut down, cream processed is finished.Cream condition processed is creme density 1.92g/cm3, 45 DEG C, pH9 or so.
（5）Lotion progress after cream processed is filling, tubulation is carried out using PAP, finished toothpaste is obtained.
Embodiment 4
A kind of toothpaste succinct containing Chinese medicinal plant, its formula is as follows：
Wherein plant essence extraction composition formula is as follows：
Honegsukle flower P.E（5% chlorogenic acid content）6 parts；Dandelion extract（Crude drug is 10 with extract withdrawal ratio:1）10 parts；Ginkgo biloba p.e（Pharmacopeia annex）5 parts；Ganodenna Lucidum P.E（Crude drug is 20 with extract withdrawal ratio:1）5 parts；Pseudo-ginseng superfine powder（180 mesh）10 parts
The above-described toothpaste succinct containing Chinese medicinal plant is prepared in accordance with the following methods：
（1）Plant essence is placed in premixed device and mixed, mixing condition is normal temperature, 20r/min, 3min.
（2）According to formula ingredient proportion, by land plaster, silica and other powders are mixed after being measured with electronic weighbridge, standby in premix dry powder batch can；It is according to formula ingredient proportion, oil-soluble constitents are mutually pre- mixed, obtain oil phase；According to formula ingredient proportion, water-soluble co-solvents are mixed in water in advance, and add quantitative sorbierite, aqueous phase is obtained.
（3）The scraper of first trial operation vacuum Manufacturing medicine extract machine under vacuum conditions, after without exception, starts vavuum pump, injects water, fed intake when vacuum reaches -0.088MPa, advanced aqueous phase starts scraper, then enter oil phase glue, start stirring, control glue charging rate, prevent foaming knot grain.When vacuum reaches -0.088MPa after charging is finished, colloid mill is opened 10 minutes, stop mill 3 minutes, be then turned on shutting down after 5 minutes, stand.
（4）Open and stirring is then turned on after scraper, treat that vacuum reaches -0.088MPa, put into powder, plant is succinct while putting into, and control charging rate prevents that foaming from overflowing.Treat that charging finishes vacuum and reaches that cream face is steady in -0.088MPa reactors, opens colloid mill 10 minutes, stop mill 5 minutes, then open homogeneous 10 minutes, then stop mill 5 minutes, then open homogeneous 5 minutes, put into the essence of formula rate.Homogeneous is opened after vacuum reaches -0.088MPa 10 minutes, shut down, cream processed is finished.Cream condition processed is creme density 1.75g/cm3, 38 DEG C, pH9 or so.
（5）Lotion progress after cream processed is filling, tubulation is carried out using PAP, finished toothpaste is obtained.
The toothpaste prepared to above example 1 carries out functional test experiment, and process is as follows：
1. the succinct inhibitory action to streptococcus bacterium colony of plant in choosing the toothpaste for containing Chinese medicinal plant essence that the present invention is provided is as confirmatory experiment, it is performance assessment criteria by investigating the situation of colony growth of the streptococcus on blood agar culture-medium, blank control group and administration group are set, experimental result shows that administration group occurs without streptococcus bacterium colony, there were significant differences with blank control group, shows that plant essence has good fungistatic effect.
2. choosing Normal healthy mice 30, three groups, every group ten are randomly divided into, plant essence is injected by gavage, continuous 3d sets high dose group and low dose group, rat-tail point about 5-10mm is cut off after last dose after 1h, treats that blood voluntarily overflows, drop of blood is sucked with filter paper every 10s.From plant essence using the formation of the artificial surface of a wound to stopped bleeding time as the bleeding time, is as a result shown with good anastalsis, anastalsis imitates relation with dosage into a certain amount.
As a result show that the succinct toothpaste of plant has certain anastalsis, can effectively shorten mouse and cut the tail bleeding time, and have certain dose dependent.
3. using mice caused by dimethylbenzene xylene ear swelling as inflammatory model, positive drug control group is used as using Compound Dexamethasone ointment, first being smeared with dimethylbenzene causes mouse to produce ear swelling, then contain the toothpaste that Chinese medicinal plant is succinct in the left ear auricle positive and negative of mouse smears positive drug and this patent respectively, auris dextra is left intact, disconnected neck puts to death mouse, the auricle at the same position of bilateral ear is taken with card punch, weigh, swelling is used as using the weight difference of two auricles, Testing index is used as using swelling rate and inhibiting rate
Swelling rate (%)=[(the average swelling of the average swelling-administration group of negative control group) the average swelling of/negative control group] * 100%.
Inhibiting rate (%)=[(the average swelling rate of the average swelling rate-administration group of negative control group) the average swelling rate of/negative control group] * 100%.
As a result show that containing the succinct toothpaste of Chinese medicinal plant there is certain antiinflammatory action, inhibiting rate is less than positive drug group.
4. investigate the prevention effect to carious tooth containing the succinct toothpaste of Chinese medicinal plant by observing containing the succinct toothpaste of Chinese medicinal plant to streptococcic inhibitory action on culture medium.Reference culture is first subjected to recovery culture, taken in its third generation axenic culture, streak inoculation to corresponding culture medium, blank control group and administration group are set, and administration group is in the medium containing 20% toothpaste succinct containing Chinese medicinal plant.Culture 3d is carried out after the completion of inoculation in 37 DEG C of incubators, daily observation colony growth situation.Test result indicate that, blank control group colony growth is good, and administration group colony growth is suppressed.As a result show that containing the succinct toothpaste of Chinese medicinal plant there is certain prevention effect to carious tooth.
Claims (9)
1. a kind of toothpaste succinct containing Chinese medicinal plant, it is characterised in that include by weight part：40-55 parts of land plaster, 10-20 parts of purified water, plant 5-20 parts of extract of essence, 1-10 parts of flavouring, 1-10 parts of excipient, 5-15 parts of auxiliary material；The wherein succinct extract of plant includes 1-10 parts of Honegsukle flower P.E, 1-10 parts of dandelion extract, 0.5-5 parts of ginkgo biloba p.e, 0.5-5 parts of Ganodenna Lucidum P.E, 1-10 parts of pseudo-ginseng superfine powder；Wherein auxiliary material is one kind in guar gum, waterglass, sorbierite, propane diols, silica, Nepal's methyl esters or Nepal's propyl ester.
2. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that land plaster is 325 mesh.
3. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that flavouring is saccharin, menthol or Mint Essence.
4. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that excipient is carboxymethyl cellulose or sodium alginate.
5. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that the content of Honegsukle flower P.E Content of Chlorogenic Acid is 5%.
6. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that the withdrawal ratio of dandelion extract is 10:1.
7. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that the withdrawal ratio of Ganodenna Lucidum P.E is 20:1.
8. the toothpaste succinct containing Chinese medicinal plant according to claim 1, it is characterised in that pseudo-ginseng superfine powder particle diameter is 100-200 mesh.
9. the preparation method of the toothpaste succinct containing Chinese medicinal plant described in a kind of any one of claim 1-8, it is characterised in that step is as follows：
（1）The succinct extract of plant is placed in premixed device and mixed, mixing condition is normal temperature, 20r/min, incorporation time 3min；
（2）Other components oil-soluble material is premixed respectively with Water-solubility Material according to formula rate, cream to be made is used；
（3）Material after premix is added in vacuum Manufacturing medicine extract machine and carries out cream processed, cream condition processed is vacuum -0.085~-0.095MPa, creme density is more than 1.58g/cm3, 25-45 DEG C of temperature, pH9；
（4）Lotion after cream processed is subjected to filling and tubulation, finished toothpaste is obtained.
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| CN104188889A (en) * | 2014-08-27 | 2014-12-10 | 仙芝科技(福建)股份有限公司 | Lucid ganoderma toothpaste |
| CN106109382A (en) * | 2016-07-31 | 2016-11-16 | 申秋英 | Aminoacid toothpaste preparation method |
| US9517197B1 (en) * | 2015-12-15 | 2016-12-13 | Jiangsu Daocheng Biotechnology Co., Ltd. | Toothpaste composition containing ganoderma lucidum component and preparation method thereof |
| CN106309215A (en) * | 2016-08-24 | 2017-01-11 | 宁波枫叶杰科生物技术有限公司 | Toothpaste containing herbal essence extract |
| CN106361671A (en) * | 2016-10-15 | 2017-02-01 | 北海益生源农贸有限责任公司 | Antibacterial anti-inflammation toothpaste and preparation method thereof |
| CN108836989A (en) * | 2018-08-31 | 2018-11-20 | 大连丹特生物技术有限公司 | A kind of composition and its preparation method and application with hemostatic bacteriostatic function |
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| CN104188889B (en) * | 2014-08-27 | 2017-04-05 | 仙芝科技(福建)股份有限公司 | ganoderma toothpaste |
| US9517197B1 (en) * | 2015-12-15 | 2016-12-13 | Jiangsu Daocheng Biotechnology Co., Ltd. | Toothpaste composition containing ganoderma lucidum component and preparation method thereof |
| CN106109382A (en) * | 2016-07-31 | 2016-11-16 | 申秋英 | Aminoacid toothpaste preparation method |
| CN106309215A (en) * | 2016-08-24 | 2017-01-11 | 宁波枫叶杰科生物技术有限公司 | Toothpaste containing herbal essence extract |
| CN106361671A (en) * | 2016-10-15 | 2017-02-01 | 北海益生源农贸有限责任公司 | Antibacterial anti-inflammation toothpaste and preparation method thereof |
| CN108836989A (en) * | 2018-08-31 | 2018-11-20 | 大连丹特生物技术有限公司 | A kind of composition and its preparation method and application with hemostatic bacteriostatic function |
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Application publication date: 20140702 |