CN106309215A - Toothpaste containing herbal essence extract - Google Patents

Toothpaste containing herbal essence extract Download PDF

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Publication number
CN106309215A
CN106309215A CN201610714333.XA CN201610714333A CN106309215A CN 106309215 A CN106309215 A CN 106309215A CN 201610714333 A CN201610714333 A CN 201610714333A CN 106309215 A CN106309215 A CN 106309215A
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CN
China
Prior art keywords
extract
herbal essences
weight
herbal
toothpaste
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610714333.XA
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Chinese (zh)
Inventor
胡奕清
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ningbo Maple Leaf Jieke Biological Technology Co Ltd
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Ningbo Maple Leaf Jieke Biological Technology Co Ltd
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Priority to CN201610714333.XA priority Critical patent/CN106309215A/en
Publication of CN106309215A publication Critical patent/CN106309215A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses toothpaste containing herbal essence extract, prepared from, gypsum powder, purified water, corrective agent, excipient, accessories and herbal essence extract, with accessories including guar gum, sodium silicate, sorbic alcohol, propylene glycol, silicon dioxide, and Nepal methyl (or Nepal silica). The components are, by weight, 44-45% of gypsum powder, 12-18% of purified water, 2-8% of corrective agent, 2-8% of excipient, 8-12% of accessories and 12-20% of herbal essence extract; wherein the herbal essence extract is prepared from, by weight, 60-65% of total flavonoids, 1.3-1.8% of amino acid, 0.8-1.1% of phytosterin, 0.5-1% of tannin, 0.6-1.3% of vitaminm, 0.2-0.3% of superoxide dismutase, and the rest of impurity substance. The toothpaste contains a variety of effective components of Chinese herbal medicine which are reasonably mixed and with high concentration, presenting multiple functions.

Description

A kind of toothpaste containing herbal essences extract
Technical field
The present invention relates to household chemicals field, particularly relate to a kind of toothpaste containing herbal essences extract.
Background technology
Along with the development of science and technology, human health problems increasingly becomes problem of concern, along with the model of diet Enclosing increasingly wider, our oral health issue is increasingly severe.Illness finds its way in by the mouth, and the kind of people's diet of modern society is more come The most miscellaneous, the time of diet is more and more changeable, and tooth is also a most important pass as the first pass of our diet link, is faced with Increasingly stern challenge.In recent years, the dentistry of each hospital becomes popular section office, city crowd more or less have tooth The epidemic disease of aspect, dental caries, decayed tooth, anaphylaxis dentine, gingivitis, periodontitis etc. have had influence on our daily life the most deeply Live, among many people are just enduring the worries can't have dinner because having a toothache to the fullest extent and decocting.
Toothpaste can effectively keep the sanitation and hygiene of tooth, and can effectively gingival disease, such as gingivitis, gingiva Hemorrhage, gingiva is got angry.In recent years Chinese herbal medicine extract or crude drug are added the Chinese herbal medicine effect type toothpaste obtained by toothpaste Increasingly by accreditation and the purchase of consumers in general.At present existing multiple domestic brands are at commercial type, such as Radix Zanthoxyli, Luclean, Radix Notoginseng, YUNNAN BAIYAO etc., the draft that external Colgate-Palmolive, Crest etc. are also proposed oneself one after another immediately following trend is general Read toothpaste.
But the most existing herbal essences toothpaste major part effect is the best, generally have following several defect: 1. with The mode of production Chinese medicine decocts and is brewed into medicinal liquid or Chinese medicine is made imperceptible fine powder, is mixed into toothpaste matrix and i.e. can get institute The herbal essences toothpaste of meaning.The use of this toothpaste is because brushing time is limited, and powdery Chinese medicine has little time to play a role, medicinal liquid shape The Chinese medicine that formula is mixed into also usually because concentration is too low and poor effect.2. the kind of Chinese herbal medicine is less, arranges in pairs or groups unreasonable, it is impossible to full Comprehensive requirement of foot mouth care.
Grass, Folium Mori, Fructus Rosae Normalis are most commonly seen but that effect is splendid herbaceous plant, and it has well health care to human body Effect, and with low cost.Grass can heat-clearing and toxic substances removing, inducing diuresis to remove edema, external curing carbuncle furuncle and phyma poison, eczema, venom etc., and right Gram positive bacteria such as staphylococcus aureus, streptococcus faecalis, streptococcus pneumoniae, diphtheria corynebacterium, anthrax bacillus, bacillus subtilis and wax Sample bacillus has obvious inhibiting effect.Folium Mori contain the compositions such as substantial amounts of protein, polysaccharide, total flavones and alkaloid and show Go out multiple biological activity.Fructus Rosae Normalis has removing toxic substances, stomach invigorating, helps digestion, the function of silt of invigorating blood circulation, change, and can play the mystery of cancer-resisting Effect.The extract of these three plant, the most single extract or combinations thereof, for toothpaste research the most not yet Appear in the newspapers.
Summary of the invention
For drawbacks described above present in prior art, effectively become it is desirable to provide a kind of containing multiple Chinese herbal medicine Divide, beneficiating ingredient collocation is reasonable, concentration is high, have the toothpaste containing herbal essences extract of multi-efficiency.
To achieve these goals, the present invention by the following technical solutions: a kind of toothpaste containing herbal essences extract, Component includes Gypsum Fibrosum powder, purified water, correctives, excipient, adjuvant, herbal essences extract, adjuvant be guar gum, waterglass, One in sorbitol, propylene glycol, silicon dioxide, Nepal's methyl ester or Nepal's propyl ester, its each component includes by weight: stone Cream powder 45-55%, purified water 12-18%, correctives 2-8%, excipient 2-8%, adjuvant 8-12%, herbal essences extract 10-20%; Wherein, herbal essences extract contains by weight: total flavones 60-65%, amino acid/11 .3-1.8%, plant sterol 0.8-1.1%, Tannin 0.5-1%, vitamin 0.6-1.3%, superoxide dismutase 0.2-0.3%, surplus is impurity.
The above-mentioned toothpaste containing herbal essences extract, wherein: described composition by weight be preferably Gypsum Fibrosum powder 50%, Purified water 14%, correctives 4%, excipient 5%, adjuvant 10%, herbal essences extract 17%.
The above-mentioned toothpaste containing herbal essences extract, wherein: the raw material of described herbal essences extract is fresh Grass, Folium Mori, Fructus Rosae Normalis, match ratio is weight ratio 3:1:1.
Compared with the prior art, due to the fact that and have employed such scheme, have the advantage that in herbal essences extract The net content of each beneficiating ingredient is high, has reached self more than 65%, also accounts for about the 6.5-13% of toothpaste gross weight, therefore its Pharmacologic action is the most obvious;The total flavones contained in herbal essences extract is up to 60-65%, from grass and Folium Mori, kind bag Include and comprise rutin, Quercetin, isoquercitrin, luteolin, vitexin etc., there is the strongest antioxidation, eliminate free radical, guarantor Protect blood vessel, dredge microcirculatory effect;Aminoacid is mainly derived from Folium Mori and Fructus Rosae Normalis, and content also reaches 1.3-1.8%, kind bag Include whole 20 several amino acids necessary to human body;Content of phytosterol 0.8-1.1%, is mainly derived from Folium Mori, has good Antioxidant, and in terms for the treatment of ulcer, there is special effect;Tannin content 0.5-1%, mostlys come from Fructus Rosae Normalis, and tannin has removing certainly By base, the metabolic effect of promotion Stomatocyte;Vitamin 0.6-1.3%, is mainly derived from Fructus Rosae Normalis and Folium Mori, contains The necessary vitamin A of human body, B2, C, D, E, P etc., vitamin B2 therein can treat cheilitis and glossitis;Superoxide dismutase Being mainly derived from Fructus Rosae Normalis and Folium Mori, content has reached 0.2-0.3%, is internationally recognized to have anti-ageing, the active matter of protective effect on cancer risk Matter, also has the effect of antiviral.To sum up, to have the strongest sterilization, antiviral, elimination words scorching for this herbal essences extract The multiple efficacies such as disease, protection oral cavity blood vessel, treatment ulcer.
Detailed description of the invention
Embodiment 1:
A kind of toothpaste containing herbal essences extract, each component includes by weight: Gypsum Fibrosum powder 50%, purified water 14%, taste masking Agent 4%, excipient 5%, adjuvant 10%, herbal essences extract 17%;Wherein, herbal essences extract contains by weight: always yellow Ketone 60-65%, amino acid/11 .3-1.8%, plant sterol 0.8-1.1%, tannin 0.5-1%, vitamin 0.6-1.3%, superoxides discrimination Changing enzyme 0.2-0.3%, surplus is impurity;Total flavones in herbal essences extract, comprise rutin, Quercetin, isoquercitrin, The kind that luteolin, vitexin and other content are relatively low.
The preparation method of this herbal essences extract is discussed in detail in another part of invention that the present inventor applies on the same day, Make a summary as follows:
1) raw material is chosen: raw material is fresh grass, Folium Mori, Fructus Rosae Normalis, and match ratio is weight ratio 3:1:1;
2) pulverize: mixing raw material powder is broken into coarse powder, and fineness is not more than 5 millimeters;
3) sterilization: made thinner by raw material on a moving belt, uses ultraviolet sterilization in course of conveying;
4) grind: raw material meal is added the water of its 50% weight, use high-strength ceramic ball that mixing is ground, thin to slurry Mill is stopped in degree D90≤300 micron, crosses 40 mesh sieves and goes out mill;
5) soak: adding ethanol in filtrate, the ethanol volumetric concentration of regulation solution is 60-75%, stands 4-5 hour after stirring;
6) dissolve: solution is applied pulse ultrasonic wave, and parameter is repetition rate 50-100HZ, power 400-500w, and the time is 40- 50 minutes;
7) filter: filter precipitation, leave and take filtrate;
8) it is dried: be spray-dried, obtain described herbal essences extract.
Embodiment 2:
A kind of toothpaste containing herbal essences extract, each component includes by weight: Gypsum Fibrosum powder 55%, purified water 18%, taste masking Agent 2%, excipient 7%, adjuvant 8%, herbal essences extract 10%.The details of herbal essences extract as described in Example 1, Hereinafter repeat no more.
Embodiment 3:
A kind of toothpaste containing herbal essences extract, each component includes by weight: Gypsum Fibrosum powder 45%, purified water 13%, taste masking Agent 8%, excipient 2%, adjuvant 12%, herbal essences extract 20%.
Embodiment 4:
A kind of toothpaste containing herbal essences extract, each component includes by weight: Gypsum Fibrosum powder 52%, purified water 12%, taste masking Agent 4%, excipient 8%, adjuvant 9%, herbal essences extract 15%.
The toothpaste of above-mentioned each embodiment, through clinical trial, uses ordinary toothbrush, calculates with 2-3 minute brushing time, energy Effectively kill noxious bacteria more than 98% in oral cavity, effectively alleviate gingival hemorrhage, gingivitis, oral ulcer symptom, life-time service energy Make oral cavity blood vessel be protected and more there is elasticity, using other toothpaste instead and also significantly reduce gingival hemorrhage symptom.
Described above to the disclosed embodiments, only for making professional and technical personnel in the field be capable of or using this Invention.Multiple amendment to these embodiments will be apparent from for those skilled in the art, herein institute The General Principle of definition can realize without departing from the spirit or scope of the present invention in other embodiments.Therefore, The present invention is not intended to be limited to the embodiments shown herein, and is to fit to special with principles disclosed herein and novelty The widest scope that point is consistent.

Claims (3)

1. containing the toothpaste of herbal essences extract, component include Gypsum Fibrosum powder, purified water, correctives, excipient, adjuvant, Herbal essences extract, adjuvant is guar gum, waterglass, sorbitol, propylene glycol, silicon dioxide, Nepal's methyl ester or Nepal One in propyl ester, it is characterised in that each component includes by weight: Gypsum Fibrosum powder 45-55%, purified water 12-18%, correctives 2- 8%, excipient 2-8%, adjuvant 8-12%, herbal essences extract 10-20%;Wherein, herbal essences extract contains by weight: Total flavones 60-65%, amino acid/11 .3-1.8%, plant sterol 0.8-1.1%, tannin 0.5-1%, vitamin 0.6-1.3%, super oxidation Thing dismutase 0.2-0.3%, surplus is impurity.
Toothpaste containing herbal essences extract the most according to claim 1, it is characterised in that: described composition by weight It is preferably Gypsum Fibrosum powder 50%, purified water 14%, correctives 4%, excipient 5%, adjuvant 10%, herbal essences extract 17%.
Toothpaste containing herbal essences extract the most according to claim 1 and 2, it is characterised in that: described herbal essences The raw material of extract is fresh grass, Folium Mori, Fructus Rosae Normalis, and match ratio is weight ratio 3:1:1.
CN201610714333.XA 2016-08-24 2016-08-24 Toothpaste containing herbal essence extract Pending CN106309215A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112120987A (en) * 2020-11-01 2020-12-25 贵州锦黔商贸有限公司 Roxburgh rose VC toothpaste and preparation method thereof
WO2021062607A1 (en) * 2019-09-30 2021-04-08 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid
US11690792B2 (en) 2019-09-30 2023-07-04 The Procter & Gamble Company Oral care compositions comprising hops beta acids and metal ions

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146311A (en) * 1995-09-23 1997-04-02 林叔明 Mulberry leaves food and articles for use
CN103385805A (en) * 2013-07-18 2013-11-13 广州薇美姿个人护理用品有限公司 Composite children toothpaste suitable for use in the morning and in the evening and children toothpaste suitable for use in the evening
CN103893074A (en) * 2014-04-16 2014-07-02 南京中科集团股份有限公司 Toothpaste containing traditional Chinese medicine plant essences and preparation method of toothpaste
CN105769705A (en) * 2016-04-23 2016-07-20 李大兴 Mulberry leaf and mulberry fruit antibacterial toothpaste

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1146311A (en) * 1995-09-23 1997-04-02 林叔明 Mulberry leaves food and articles for use
CN103385805A (en) * 2013-07-18 2013-11-13 广州薇美姿个人护理用品有限公司 Composite children toothpaste suitable for use in the morning and in the evening and children toothpaste suitable for use in the evening
CN103893074A (en) * 2014-04-16 2014-07-02 南京中科集团股份有限公司 Toothpaste containing traditional Chinese medicine plant essences and preparation method of toothpaste
CN105769705A (en) * 2016-04-23 2016-07-20 李大兴 Mulberry leaf and mulberry fruit antibacterial toothpaste

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021062607A1 (en) * 2019-09-30 2021-04-08 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid
US11690792B2 (en) 2019-09-30 2023-07-04 The Procter & Gamble Company Oral care compositions comprising hops beta acids and metal ions
US11696881B2 (en) 2019-09-30 2023-07-11 The Procter & Gamble Company Oral care compositions comprising hops beta acids and fluoride ions
US11918681B2 (en) 2019-09-30 2024-03-05 The Procter & Gamble Company Oral care compositions comprising hops beta acid and amino acid
CN112120987A (en) * 2020-11-01 2020-12-25 贵州锦黔商贸有限公司 Roxburgh rose VC toothpaste and preparation method thereof

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