CN100558376C - Plain tablet of peppery second and preparation technology thereof - Google Patents
Plain tablet of peppery second and preparation technology thereof Download PDFInfo
- Publication number
- CN100558376C CN100558376C CNB031146112A CN03114611A CN100558376C CN 100558376 C CN100558376 C CN 100558376C CN B031146112 A CNB031146112 A CN B031146112A CN 03114611 A CN03114611 A CN 03114611A CN 100558376 C CN100558376 C CN 100558376C
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- peppery
- ethanol
- rhizoma corydalis
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Abstract
Plain sheet of knotweed second of the present invention and preparation technology thereof provide treatment various traumatic infection medicinal preparation for oral administration, this medicament is made by Herba polygoni hydropiperis and the Rhizoma Corydalis two flavor Chinese crude drug sides of closing, preparation technology produces soft extracts with decoction alcohol precipitation method and alcohol extracting method respectively, and mix homogeneously after dry, the powder process, granulation again, tabletting, outer sugar coating, packing, preparation technology's standard, effectively medical substance extraction ratio height, this tablet have promoting the circulation of QI to relieve pain, the hemostasis invigorate blood circulation, antimicrobial and anti-inflammation efficacy, be used for the treatment of various traumatic infections.
Description
Technical field
Plain tablet of the peppery second of the present invention and preparation technology thereof belong to pure compound Chinese medicinal preparation and preparation technology thereof, relate in particular to compound preparation and preparation technology thereof that Chinese crude drug extracts effective medical substance.
Background technology
Traumatic infection is war, rescue and relief work, unexpected injury, mechanically actuated, easily send out sick and wounded in surgical injury and the daily work, infect generally by due to gram negative strain and the gram positive bacterial strain, the former is a bacillus pyocyaneus, with escherichia coli is many, the latter is that staphylococcus aureus and Candida albicans are many, the traditional treatment medicine is based on medicine for external use, mostly the Chinese medicine preparation of the treatment traumatic infection of market sale is powder and ointment, prescription medicine is many in the prescription, the oral traditional Chinese medicine preparation seldom particularly only uses the treatment traumatic infection oral compound preparation of two kinds of Chinese crude drugs rarely found in the prescription.
Summary of the invention
The objective of the invention is:
The medical substance of selecting for use two kinds of Chinese crude drugs to extract is formed prescription, produce have promoting the circulation of QI to relieve pain, hemostasis is invigorated blood circulation, the herbal mixture tablet of anti-inflammation function, is used for orally, treat various traumatic infections, and reach safe, effective, inexpensive, practical.
In order to realize the purpose of foregoing invention, the technical scheme that plain tablet of the peppery second of the present invention and preparation technology thereof take is:
The plain sheet of peppery second is by Herba polygoni hydropiperis and two kinds of Chinese crude drug compositing formulas of Rhizoma Corydalis, and extracts medical substance respectively and make tablet.In preparation process, earlier complete three decoctings of medicine employing of Herba polygoni hydropiperis and ethanol precipitation are collected thick paste, and it is standby that the thick paste spray drying is made fine powder; Again vinegar system Rhizoma Corydalis is adopted twice pure extracting method to collect thick paste, and it is standby that the thick paste spray drying is made fine powder,, behind the outer sugar coating of tabletting, be packaged into Chinese patent medicine at last with two kinds of fine powder mixings, oral for the patient.According to traditional Chinese medicine theory, Herba polygoni hydropiperis has effects such as expelling wind and removing dampness, heat-clearing and toxic substances removing, hemostasis and anti-inflammation, killing parasites for relieving itching, the diseases such as dysentery, enteritis that are used for the treatment of for oral administration, Rhizoma Corydalis then have invigorate blood circulation, the function of promoting the circulation of QI, pain relieving, diseases such as the orally taken for curing breast side of body, abdominal cavity pain, treating swelling and pain by traumatic injury, two medicines are collaborative plays heat clearing away, detoxifcation, pain relieving, antiinflammatory, antidiarrheal, hemostasia effect altogether, effectively treats traumatic infection.According to modernization of Chinese medicine theory, in the plain sheet prescription of the peppery second of the present invention, Herba polygoni hydropiperis extract has the antimicrobial acivity function based on volatile oil, tannin, Flavonoid substances, its tannin has inhibitory action to dysentery bacterium, and water extract has suitable antibacterial activity to gram negative strain; Rhizoma Corydalis is rich in tetrahydropalmatine (racemization tetrahydrochysene palm coptisine), has very strong analgesic activity on the central nervous system, can suppress and have antiulcer action, oral absorption rapidly and fully, function is based on promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain, anti-inflammation and sterilization, excellent to disease curative effects such as treatment obstruction of qi in the chest and cardialgia, epigastric pain, traumatic injury, two flavor Chinese crude drug wide material sources, be worth cheap, all have no side effect, play antiinflammatory, pain relieving, hemostatic healing efficacy behind the side of closing altogether, the triple effect unification, curative effect is rapid, and has no side effect.
Plain sheet of the peppery second of the present invention and preparation technology's thereof beneficial effect is: the plain sheet of peppery second selects YAOJING few, processing technique is easy, low production cost, oral curative effect is outstanding, especially army's war wound, training being injured all diseases such as pain due to the traumatic injury, infection, hemorrhage, rheumatic arthralgia has specially good effect, has no side effect.
The specific embodiment
1, the best effectively prescription amount of each prescription in the plain sheet of peppery second, degree is as shown in the table:
| Prescription Chinese crude drug title | Formula ratio (gram) | Content (%) |
| Herba polygoni hydropiperis (herb) | 2625 | 87.5 |
| Rhizoma Corydalis (vinegar system) | 375 | 12.5 |
| Add up to | 3000 | 100 |
2, the plain sheet preparation technology of peppery second
1. get the Herba polygoni hydropiperis remove impurity, clean, cutting is standby.
2. it is standby to get the remove impurity of vinegar system Rhizoma Corydalis.
3. 2625 gram Herba polygoni hydropiperis medical herbs are added 10 times of water gagings at every turn decoct three times, each 1 hour, collecting decoction filtered, and concentrating under reduced pressure is used 95% ethanol precipitation, reclaims ethanol to thick paste, and spray drying powder process is standby.
4. vinegar system Rhizoma Corydalis 375 grams were added 3 times of amount 60% soak with ethanol 24 hours, heating and refluxing extraction 3 hours is emitted extracting liquid filtering, add 2 times of amount 60% ethanol again, heating and refluxing extraction 2 hours is emitted extracting liquid filtering, 2 filtrates are merged, reclaim ethanol and be paste, spray drying powder process is standby.
5. above two kinds of standby fine powders are merged, mixed pelletization, tabletting add sugar-coat, every heavy 0.3 gram, the packing back patent medicine.
3, plain sheet instructions of taking of peppery second and consumption:
Oral for the patient, be grown up 3 times on the one, each 2-3 sheet, the child is not taken by pregnant women.
Claims (2)
1, the plain sheet of a kind of peppery second is characterized in that being made by following raw material medicines in percentage by weight: Herba polygoni hydropiperis 87.5%, vinegar system Rhizoma Corydalis 12.5%.
2, the preparation technology of the plain sheet of peppery second according to claim 1, it is characterized in that: get Herba polygoni hydropiperis, clean system takes by weighing 2625 grams, adds 10 times of decoctings at every turn and boils three times, each 1 hour, collecting decoction filters, and uses 95% ethanol precipitation behind the concentrating under reduced pressure, reclaims ethanol to thick paste, spray drying powder process is standby, took by weighing 3 times of amounts of 375 gram addings, 60% soak with ethanol 24 hours after getting the remove impurity of vinegar system Rhizoma Corydalis again, heating and refluxing extraction 3 hours is emitted extracting liquid filtering, adding 2 times of amount 60% alcohol heating reflux again extracted 2 hours, emit extracting liquid filtering, 2 filtrates are merged, reclaim ethanol and be paste, spray drying powder process is standby, at last above two kinds of fine powders are merged mixed pelletization, tabletting adds sugar-coat, every heavy 0.3 gram gets patent medicine after the packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031146112A CN100558376C (en) | 2003-04-07 | 2003-04-07 | Plain tablet of peppery second and preparation technology thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB031146112A CN100558376C (en) | 2003-04-07 | 2003-04-07 | Plain tablet of peppery second and preparation technology thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1535709A CN1535709A (en) | 2004-10-13 |
| CN100558376C true CN100558376C (en) | 2009-11-11 |
Family
ID=34320215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB031146112A Expired - Fee Related CN100558376C (en) | 2003-04-07 | 2003-04-07 | Plain tablet of peppery second and preparation technology thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100558376C (en) |
-
2003
- 2003-04-07 CN CNB031146112A patent/CN100558376C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1535709A (en) | 2004-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20091111 Termination date: 20120407 |