CN101843683B - Inflammation-diminishing and muscle-growing oil - Google Patents
Inflammation-diminishing and muscle-growing oil Download PDFInfo
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- CN101843683B CN101843683B CN201010177080XA CN201010177080A CN101843683B CN 101843683 B CN101843683 B CN 101843683B CN 201010177080X A CN201010177080X A CN 201010177080XA CN 201010177080 A CN201010177080 A CN 201010177080A CN 101843683 B CN101843683 B CN 101843683B
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Abstract
The invention belongs to the medicine field and particularly relates to inflammation-diminishing and muscle-growing oil, which is prepared by decocting a mixed medicine by edible vegetable oil with slow fire and then filtering, wherein, the ratio of the edible vegetable oil to the mixed medicine is 3:1-5:1; the mixed medicine is prepared by mixing a heat-clearing antimicrobial drug, sanguisorba officinalis, polygonum cuspidatum, schisandra chinensis, semen strychni and borneol; and the heat-clearing antimicrobial drug is one or a mixture of coptis chinensis and radix scutellariae. The inflammation-diminishing and muscle-growing oil has simple process and low manufacture cost; treatment of diminishing inflammation, easing pain and growing muscle can be effectively carried out to a superficial wound through extracting effective ingredients of the medicine by edible oil; the oil has strong effects of antibiosis, astringency, relieving swelling and promoting wound healing, can promote the growth of a granulation tissue and newly born epithelium and shorten the time of wound healing, has wide indications, and can be taken as one of the standing medicine in a health-care and treating medicine box for families.
Description
Technical field
The invention belongs to field of medicaments, be specifically related to a kind of inflammation-diminishing and muscle-growing oil antibacterial, the dephlogistication and promoting nuscle growth effect that has.
Background technology
Wound especially burn and scald, skin is frustrated the epidermis sexual trauma inflammation that easy bacterial infection causes because of wound exposes such as sassafras wound, is one of commonly encountered diseases, frequently-occurring disease of surgery, department of dermatologry.Treat untimely frequent secondary systemic infection, septicemia, serious consequences such as shock, even cause death.The specific medicament of these diseases of treatment seldom at present, mainly be to rely on antibacterials directly to kill or suppress the microbial growth breeding for a long time, reach the purpose of treatment, but curative effect is satisfied not to the utmost, only can antibiotic, infection, no granulation promoting analgesic effect, and multiple medicine is used repeatedly, causes bacterial drug resistance to take place easily, reduces the fungistatic effect of antibiotics, and purposes is single, and blood circulation promoting and blood stasis dispelling, dephlogistication and promoting nuscle growth ability have nothing in common with each other.Some are also arranged is the medicine for external use of raw material with the Chinese herbal medicine, exists in various degree that types of medicines is various, mechanism is not clear, curative effect is not high, the course of treatment is very long, complicated process of preparation, cost are crossed high deficiency.
Summary of the invention
The purpose of this invention is to provide a kind of inflammation-diminishing and muscle-growing oil, utilize the extraction of edible oil to effective ingredient, the shallow sexual trauma of his-and-hers watches carries out the treatment of anti-inflammation, debridement pain relieving, convergence granulation promoting effectively, effect with clean wound, can promote the growth of granulation tissue and new epithelize, greatly shorten the time of wound healing, facts have proved that antiinflammatory life oil hinders under the prerequisite of face immediate union guaranteeing, reduce medical expense significantly.
The technical solution adopted in the present invention:
A kind of inflammation-diminishing and muscle-growing oil is with edible vegetable oil hybrid medicine to be carried out making after filtration after slow fire decocts, and wherein the ratio of edible vegetable oil and hybrid medicine is 3: 1～5: 1 by weight; Described hybrid medicine is to be mixed by heat clearing away antimicrobial drug, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Fructus Schisandrae Chinensis, Semen Strychni and Borneolum Syntheticum, and wherein each components contents is by weight percentage: heat clearing away antimicrobial drug 35%～50%, Radix Sanguisorbae 13%～17%, Rhizoma Polygoni Cuspidati 8%～13%, Fructus Schisandrae Chinensis 13%～17%, Semen Strychni 13%～17%, Borneolum Syntheticum 3%～8%; Described heat clearing away antimicrobial drug is meant a kind of or mixing in Rhizoma Coptidis or the Radix Scutellariae.
Described edible vegetable oil is meant Oleum Arachidis hypogaeae semen, Oleum sesami, Oleum Brassicae campestris or Oleum Helianthi.
The preparation method of above-mentioned inflammation-diminishing and muscle-growing oil: after medicine cleaned filter and do, heat clearing away antimicrobial drug, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Fructus Schisandrae Chinensis and Semen Strychni joined carry out slow fire in the edible vegetable oil and decoct, when treating the medicinal residues zoom, filter, then Borneolum Syntheticum is added in the oil, bottling is sealed up for safekeeping stand-by.
Rhizoma Coptidis: have heat clearing and damp drying, the merit of eliminating fire and detoxication.Tool very wide antimicrobial spectrum, can suppress the growth and the breeding of various bacteria.And can strengthen leukocytic phagocytic activity.
Radix Scutellariae: performance and effect and Rhizoma Coptidis are close.
Radix Sanguisorbae: bitter in the mouth cold in nature, cooling blood for hemostasis, wound is held back in detoxifcation, and minimizing is oozed out, and the convergence wound promotes healing.
Rhizoma Polygoni Cuspidati: heat-clearing and toxic substances removing, stasis-dispelling and pain-killing is suitable for burn and scald, carbuncle sore tumefacting virus.
Fructus Schisandrae Chinensis: the nourishing kidney of astringing the lung, the arresting sweating that promotes the production of body fluid, the sour in the mouth convergence reduces the wound sepage, keeps the wound drying, helps wound healing.
Semen Strychni: mass dissipating and swelling eliminating, removing obstruction in the collateral to relieve pain (sensory nerve ending is had the paralysis effect), poisonous should the use as one feels fit.
Borneolum Syntheticum: clearing up internal heat by using drugs of bitter in taste and cold in nature, detumescence relieves the pain, removing the necrotic tissue and promoting granulation.
Edible vegetable oil: decoct the effective ingredient that can fully extract in the medicine through slow fire; Be coated in and hinder on the face, can prevent the intrusion of antibacterial in the air; Oil gauze is dry gradually in the surplus that medicine infiltrates, and continues protection and hinders face, promotes to hinder face healing acceleration under gnotobasis.
Check:
One, toxicity inspection
Get 20 mices and record median lethal dose(LD 50) LD by acute oral toxicity test
50＞5g/kg (gets LD
50Be the 5g/kg body weight) calculate the cumulative toxicity poisoning dosage, the 1st～4 day poisoning dosage is 0.1LD
50, increased progressively once in per four days by 1.5 times with post dose, until 20 days, result of the test saw Table one.
Table one cumulative toxicity test result
| Contamination natural law (day) | Poisoning dosage * LD 50 | Accumulated dose * LD 50 | Animal dead number (only) |
| 1～4 | 0.10 | 0.40 | 0 |
| 5～8 | 0.15 | 1.00 | 0 |
| 9～12 | 0.22 | 1.88 | 0 |
| 13～16 | 0.34 | 3.24 | 0 |
| 17～20 | 0.50 | 5.24 | 0 |
Conclusion: administration 20 days, accumulated dose are 5.24 * LD
50, not seeing animal dead, the present invention is weak cumulative toxicity to cumulative coefficient K＞5 of mice.
Two, bactericidal assay
To coliform, golden Portugal bacterium, read bacterium in vain and carry out quantitative disinfecting test, result of the test sees Table two.
The killing effect of table two test organisms
Conclusion: the present invention to coliform, golden Portugal bacterium, read bacterium in vain and all have stronger killing effect, bacteriostasis is obvious.
Three, animal experiment
Choose 12 rabbit and be divided into administration group and matched group.The helix of every rabbit immersed respectively in 53 ℃ the hot water 3 minutes, and caused the II degree to scald, be coated with full medicine then on the ear of the rabbit of administration group, be coated with once in per 3 minutes, not medication of matched group is used for controlled observation.
To color, swelling degree, the erosion of observing helix behind every rabbit dipping bath in 8,16,24,48,74,96 hours and situation about infecting.
The result: it is volume gain that the rabbit ear of matched group begins hyperemia, swelling, helix, blister occurred in 16 hours, peaked in 24 hours, after 48 hours helix partly peel, rotten to the corn, infect; Administration group helix is obviously lighter, does not have decortication, rotten to the corn and infection generation, and swelling is disappeared substantially after 72 hours, recovers from injury.
Conclusion: the present invention has effect antibiotic, that restrain, subside a swelling, promote wound healing.
Clinical example: the male patient, 30 years old, outside boiled water was scalded 2 hours before the left leg, and the shallow II degree of area 16cmx28cm. has blister, and causalgia is violent.After cutting off the blister skin, stick the gauze that inflammation-diminishing and muscle-growing oil soaks, " ache and promptly end ".Check after three days sees that two places still have and ooze out (respectively have an appointment 1.5cmx2cm and 2cmx2cm, and a little sepage is arranged), will have to ooze out the gauze of heaving and cut off unction gauze once more, tears the gauze that has become dry after five days gently off, hinders face and heals fully.
Technology of the present invention is simple, cost of manufacture is low, utilize the extraction of edible oil to effective ingredient, effectively the shallow wound is carried out the treatment of anti-inflammatory analgetic, convergence granulation promoting, have stronger antibiotic, convergence, detumescence, promote the effect of wound healing, can promote granulation tissue and newborn epithelial growth, shorten the time of wound healing.Can be used as one of medicament categories in the standing health therapy medicine-chest of family.
The specific embodiment
The present invention will be further described with indefiniteness embodiment below.
Embodiment one
Get Rhizoma Coptidis 2.4kg, Radix Sanguisorbae 0.8kg, Rhizoma Polygoni Cuspidati 0.5kg, Fructus Schisandrae Chinensis 0.9kg, Semen Strychni 0.9kg and join and carry out slow fire in the 20kg Oleum Arachidis hypogaeae semen and decoct, when treating the medicinal residues zoom, filter, then will Borneolum Syntheticum 0.2kg add in the oil inflammation-diminishing and muscle-growing oil, bottling is sealed up for safekeeping stand-by.
Embodiment two
Getting Rhizoma Coptidis 1.5kg, Radix Scutellariae 1.2kg, Radix Sanguisorbae 0.9kg, Rhizoma Polygoni Cuspidati 0.8kg, Fructus Schisandrae Chinensis 1.0kg, Semen Strychni 1.0kg joins and carries out slow fire in the 30kg Oleum Arachidis hypogaeae semen and decoct, when treating the medicinal residues zoom, filter, then Borneolum Syntheticum 0.4kg is added the interior inflammation-diminishing and muscle-growing oil that gets of oil, bottling is sealed up for safekeeping stand-by.
Embodiment three
Getting Rhizoma Coptidis 1.5kg, Radix Scutellariae 2.5kg, Radix Sanguisorbae 1.5kg, Rhizoma Polygoni Cuspidati 1.0kg, Fructus Schisandrae Chinensis 1.3kg, Semen Strychni 1.3kg joins and carries out slow fire in the 45kg Oleum Arachidis hypogaeae semen and decoct, when treating the medicinal residues zoom, filter, then Borneolum Syntheticum 0.6kg is added the interior inflammation-diminishing and muscle-growing oil that gets of oil, bottling is sealed up for safekeeping stand-by.
Embodiment four
Get Radix Scutellariae 2.5kg, Radix Sanguisorbae 1.0kg, Rhizoma Polygoni Cuspidati 0.8kg, Fructus Schisandrae Chinensis 0.9kg, Semen Strychni 1.0kg and join and carry out slow fire in the 30kg Oleum Arachidis hypogaeae semen and decoct, when treating the medicinal residues zoom, filter, then will Borneolum Syntheticum 0.5kg add in the oil inflammation-diminishing and muscle-growing oil, bottling is sealed up for safekeeping stand-by.
Claims (2)
1. the inflammation-diminishing and muscle-growing oil of an external is characterized in that with edible vegetable oil hybrid medicine being carried out making after filtration after slow fire decocts, and wherein the ratio of edible vegetable oil and hybrid medicine is 3: 1～5: 1 by weight; Described hybrid medicine is to be mixed by heat clearing away antimicrobial drug, Radix Sanguisorbae, Rhizoma Polygoni Cuspidati, Fructus Schisandrae Chinensis, Semen Strychni and Borneolum Syntheticum, and wherein each components contents is by weight percentage: heat clearing away antimicrobial drug 35%～50%, Radix Sanguisorbae 13%～17%, Rhizoma Polygoni Cuspidati 8%～13%, Fructus Schisandrae Chinensis 13%～17%, Semen Strychni 13%～17%, Borneolum Syntheticum 3%～8%; Described heat clearing away antimicrobial drug is meant a kind of or mixing in Rhizoma Coptidis or the Radix Scutellariae.
2. inflammation-diminishing and muscle-growing oil according to claim 1 is characterized in that: described edible vegetable oil is meant Oleum Arachidis hypogaeae semen, Oleum sesami, Oleum Brassicae campestris or Oleum Helianthi.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010177080XA CN101843683B (en) | 2010-05-04 | 2010-05-04 | Inflammation-diminishing and muscle-growing oil |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010177080XA CN101843683B (en) | 2010-05-04 | 2010-05-04 | Inflammation-diminishing and muscle-growing oil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN101843683A CN101843683A (en) | 2010-09-29 |
| CN101843683B true CN101843683B (en) | 2011-07-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201010177080XA Expired - Fee Related CN101843683B (en) | 2010-05-04 | 2010-05-04 | Inflammation-diminishing and muscle-growing oil |
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Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1320435A (en) * | 2000-04-26 | 2001-11-07 | 林翠兰 | Medicine for treating burn and scald |
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2010
- 2010-05-04 CN CN201010177080XA patent/CN101843683B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN101843683A (en) | 2010-09-29 |
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