CN100488497C - 白三烯阻滞剂在制备药物中的应用 - Google Patents

白三烯阻滞剂在制备药物中的应用 Download PDF

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Publication number
CN100488497C
CN100488497C CNB018118860A CN01811886A CN100488497C CN 100488497 C CN100488497 C CN 100488497C CN B018118860 A CNB018118860 A CN B018118860A CN 01811886 A CN01811886 A CN 01811886A CN 100488497 C CN100488497 C CN 100488497C
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mice
endotoxin
wild
inhalation
pulmonary
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Chinese (zh)
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CN1635923A (zh
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肯尼思·布洛克
一之濑文人
沃伦·M·扎波尔
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General Hospital Corp
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General Hospital Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CNB018118860A 2000-06-28 2001-06-22 白三烯阻滞剂在制备药物中的应用 Expired - Fee Related CN100488497C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/605,900 US6601580B1 (en) 2000-06-28 2000-06-28 Enhancing therapeutic effectiveness of nitric oxide inhalation
US09/605,900 2000-06-28

Publications (2)

Publication Number Publication Date
CN1635923A CN1635923A (zh) 2005-07-06
CN100488497C true CN100488497C (zh) 2009-05-20

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Country Link
US (2) US6601580B1 (https=)
EP (1) EP1301076A4 (https=)
JP (1) JP2004509850A (https=)
KR (1) KR100849103B1 (https=)
CN (1) CN100488497C (https=)
AU (2) AU2001273622B2 (https=)
CA (1) CA2414409A1 (https=)
IL (1) IL153702A0 (https=)
MX (1) MXPA03000182A (https=)
WO (1) WO2002000175A2 (https=)

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WO2004000368A1 (en) * 2002-06-21 2003-12-31 University Of Pittsburgh Of The Commonwealth System Of Higher Education Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
US9138707B2 (en) 2002-12-10 2015-09-22 Sy Kimball Portable, nitric oxide generator
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
ES2294543T3 (es) * 2003-07-09 2008-04-01 The Government Of The United States Of America, As Represented By The Secretary, Department Of Heal Uso de sales de nitrilo para el tratamiento de afecciones cardiovasculares.
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas
AU2005244078A1 (en) 2004-05-11 2005-11-24 Pulmonox Technologies Corporation Intermittent dosing of nitric oxide gas
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
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WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
WO2007057763A2 (en) * 2005-11-18 2007-05-24 Pulmonox Technologies Corporation Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
US8790715B2 (en) 2006-02-16 2014-07-29 Ino Therapeutics Llc Method and apparatus for generating nitric oxide for medical use
WO2007136789A2 (en) * 2006-05-19 2007-11-29 Medimmune, Inc. Methods of preventing, treating or ameliorating enhanced respiratory disease via innate immune mechanisms
FR2902002B1 (fr) * 2006-06-12 2010-08-27 Lvmh Rech Composition cosmetique anti-radicaux libres
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
WO2008063868A2 (en) * 2006-11-07 2008-05-29 The General Hospital Corporation Attenuation of vasoactive oxygen carrier-induced vasoconstriction
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
CA2743334A1 (en) * 2007-11-12 2009-05-22 Samsara Medicin Ab Methods relating to breathing disorders
WO2009086470A2 (en) * 2007-12-27 2009-07-09 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide - donating compounds and uses thereof
US8720436B2 (en) * 2008-01-31 2014-05-13 Genosys, Inc. Nitric oxide gel apparatus and method
US8434475B2 (en) 2008-01-31 2013-05-07 Genosys, Inc. Nitric oxide reactor and distributor apparatus and method
US9649467B2 (en) 2008-01-31 2017-05-16 Syk Technologies, Llc Nitric oxide reactor and distributor apparatus and method
US8501090B2 (en) * 2008-03-24 2013-08-06 Christian S. Minton Anti-microbial gas apparatus and method
CA2671029A1 (en) 2009-06-30 2010-12-30 James S. Baldassarre Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
JP5581500B2 (ja) * 2010-03-10 2014-09-03 学校法人北里研究所 虚血再灌流障害軽減用治療剤および治療装置
US8685467B2 (en) 2010-08-03 2014-04-01 J. W. Randolph Miller Nitric oxide generation, dilution, and topical application apparatus and method
EP2691087A2 (en) 2011-03-31 2014-02-05 László Gábor Szabó Pharmaceutical composition containing no, process for the preparation and use thereof
CN104159591A (zh) 2011-11-07 2014-11-19 通用医疗公司 红细胞的处理
US10517817B2 (en) 2013-05-09 2019-12-31 Syk Technologies, Llc Deep topical systemic nitric oxide therapy apparatus and method
EP2908137A1 (en) * 2014-02-14 2015-08-19 Institut Pasteur Methods for in vitro investigating mitochondrial replication dysfunction in a biological sample, kits and uses thereof, therapeutic methods against progeroid-like syndromes or symptomes and screening method for identifying particular protease inhibitor(s) and/or nitroso-redox stress scavenger compound(s)
JP2014141536A (ja) * 2014-05-16 2014-08-07 Kitasato Institute 虚血再灌流障害軽減用治療剤および治療装置
US10058542B1 (en) 2014-09-12 2018-08-28 Thioredoxin Systems Ab Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith
CA3009986A1 (en) * 2015-12-28 2017-07-06 Vero Biotech LLC Method and apparatus for administering nitric oxide with supplemental drugs
WO2017132275A1 (en) 2016-01-27 2017-08-03 Syk Technologies, Llc Nitric oxide topical application apparatus and methods
AU2017362500B2 (en) 2016-11-17 2024-09-26 Renovion, Inc. Treatment of Respiratory Tract Diseases and Infections with Ascorbic Acid Compositions
BR112020009910A2 (pt) 2017-11-17 2020-11-03 Renovion, Inc. composições de ácido ascórbico estáveis e métodos de usar as mesmas
CN109169638A (zh) * 2018-11-12 2019-01-11 苏州瑞徕生物科技有限公司 一种细胞保存液及其用途
US12459820B2 (en) 2020-06-11 2025-11-04 J. W. Randolph Miller Stabilized and NO2-inhibited nitric oxide generating gels for inhaled nitric oxide therapy
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Also Published As

Publication number Publication date
WO2002000175A3 (en) 2002-08-15
MXPA03000182A (es) 2004-02-26
EP1301076A2 (en) 2003-04-16
KR20030029530A (ko) 2003-04-14
JP2004509850A (ja) 2004-04-02
US6935334B2 (en) 2005-08-30
CN1635923A (zh) 2005-07-06
CA2414409A1 (en) 2002-01-03
WO2002000175A2 (en) 2002-01-03
AU7362201A (en) 2002-01-08
EP1301076A4 (en) 2004-09-22
IL153702A0 (en) 2003-07-06
US6601580B1 (en) 2003-08-05
KR100849103B1 (ko) 2008-07-30
AU2001273622B2 (en) 2007-05-10
US20030202969A1 (en) 2003-10-30

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Termination date: 20100622