Composite mold toxin sorbent
Technical field
The present invention relates to a kind of composite mold toxin sorbent.This adsorbent can be used as feed addictive and uses, and can effectively remove the mycotoxin in the feed, thereby improve livestock and poultry production performance.Belong to the feed safety field.
Background technology
Worldwide, cereal and feed all exist serious mycotoxin contamination.Mycotoxin not only can directly cause murder by poisoning to animal, also can transfer to the human body from animal by food chain.Some toxin produces some toxin related compounds by the metabolism meeting in animal body, and these compounds also can produce injury to human body through food chain.At present, in the feed processing and using, the general method of chemistry and physics that adopts removes mycotoxin.
The method of chemistry as: utilize monoethyl amine calcium hydroxide, ozone or ammoniacal liquor to wait to handle feed or its raw material, degraded mycotoxin wherein.The method of this kind chemical degradation, though can remove a certain amount of mycotoxin, its shortcoming is that specific chemical can only be degraded a kind of or a few mycotoxin; Simultaneously, these chemical substances part nutrition in the feed of also can degrading; In addition, the high residue of these chemical substances in feed produces also for the fowl dirty swine and brought negative effect.
The method of physics mainly is by suction-operated, promptly in feed, add can absorbing mycotoxin material, mycotoxin is not absorbed by animal through animal intestinal the time, directly discharge outside the animal body.These have adsorbing material, be to provide absorption required energy by discharging free energy (Δ G), its most important characteristic is the physical arrangement of these adsorbents, comprises the distribution of its total charge dosage, electric charge, the size and the available surface area (specific area) of hole.For example: natural aluminosilicate hydrochlorate zeolite, montmorillonite, diatomite, kaolin etc. because have bigger specific area and ion adsorption capacity, all have certain selection adsorption capacity to mycotoxin.But the shortcoming of physical method is also fairly obvious, for example: the absorption affinity of natural silicon aluminium acid salt mineral is little, efficient is low, account for the feed capacity big, nutriment is also had certain absorption, thereby it is bad to be directly used in the effect of feed.Therefore, people carry out modification to natural alumino-silicate, to improve its selective adsorption capacity to mycotoxin.As the hydrated sodium aluminosilicate calcium that extracts from zeolite AFB1 there is selective adsorption capacity preferably.But, when hydrated sodium aluminosilicate calcium uses separately, not strong to other mycotoxin adsorption capacity except that aflatoxin, not good as the adsorption effect of zearalenone, ochratoxin A, T-2 toxin and deoxidation being avenged rotten sickle spore bacterium enol (being vomitoxin).The generation of this situation is that different mycotoxins has diverse physicochemical property because mycotoxin has the organic compound of the complexity of different chemical constitutions as a big class.For example, the fundamental structural unit of aflatoxin is two hydrogen furan nucleus and a cumarin; Zearalenone is a kind of two phenolic compounds; Ochratoxin A is the compound with carboxyl and phenolic group group; It is sesquiterpenoid that rotten sickle spore bacterium enol is avenged in T-2 toxin and deoxidation.The negative charged surface of adsorbent (as the hydrated aluminosilicate) possess hydrophilic property that obtains based on clay class mineral is suitable for adsorbing the mould mycomycin that has polar group, as aflatoxin; The mycotoxin that those polarity are not strong (as zearalenone and ochratoxin A) then is difficult for adsorbed by this class adsorbent.In a word, hydrated aluminosilicate class adsorbent has the good adsorption ability to AFB1, but to toxin adsorption capacity deficiency (Santin such as zearalenone, ochratoxin, trichothecins, E.Paulillo, A.C.Majorka, P.C.Alessi, A.C.Krabbe, A.S.2002.The effects of ochratoxin-aluminosilicate interaction on the tissues and jumoral immune response of broilers.Avian Pathol.31 (1): 73-79).The cell wall components of yeast or yeast also can be used as mold toxin sorbent and uses.The adsorption capacity of yeast cell wall contratoxin will obviously be better than the full composition of yeast, and the special construction of this explanation yeast cell wall produces absorption affinity to mycotoxin.Polysaccharide, protein and lipid are arranged on the yeast cell wall, and these materials are realized by hydrogen bond, ionic bond and hydrophobic effect power etc. the absorption of mycotoxin.Result of the test shows that yeast cell wall can adsorb mycotoxins such as zearalenone, vomitoxin, and these mycotoxins be difficult for by hydrated aluminosilicate adsorbed (
![Figure C20061002472300041](https://patentimages.storage.googleapis.com/12/13/45/18e699305e8fbd/C20061002472300041.png)
, A.Karlovsky, P.1998.Personalcommunication, University of Hohenheim, Stuttgart, Germany;
, A.Karlovsky, P.1999.Hefen und Tonminerale binden Mycotoxine.AgrarzeitungErna ¨ hrungsdienst 24,10 April.).Simultaneously, this series products is relatively poor to the adsorption capacity of other types mycotoxin, and price is higher.
In sum, the method for the present removal mycotoxin of using, the kind of removing mycotoxin is more single, also exists the price problem of higher simultaneously.Therefore, by dissimilar adsorbents is carried out suitable proportioning, make composite mold toxin sorbent, make it to give full play to the absorption property of heterogeneity to different mycotoxins, thereby reaching the wide spectrum adsorption effect, is a research work highly significant.
Summary of the invention
The objective of the invention is at the deficiencies in the prior art, a kind of composite mold toxin sorbent is provided, can be used as feed addictive and use, effectively reduce the various mycotoxins in the feed, and have that raw material is easy to get, characteristics with low cost.
For realizing this purpose, the present invention uses the very extensive raw mineral materials that is easy to get in source, tunning extract and natral plant ingredients, adopt compound mode, the multiple adsorption effect that superposes, aspects such as the mold toxin sorbent that obtains can close at raw material, cost pass, wide spectrum absorption property realize the breakthrough of existing mold toxin sorbent technology.
Composite mold toxin sorbent of the present invention comprises as active ingredient: (a) hydrated aluminosilicate; (b) yeast cell wall; (c) water hyacinth root powder.Above-mentioned three kinds of effective ingredients are carried out mechanical mixture according to suitable ratio, make composite mold toxin sorbent.
Hydrated aluminosilicate of the present invention (commercially available), is pulverized, is sieved drying, and the weight content in mold toxin sorbent is 15-85%.
Yeast cell wall of the present invention, for yeast obtains through physical wall breaking, cell membrane extraction, drying, pulverizing, the weight content in mold toxin sorbent is 5-50%.
Water hyacinth root powder of the present invention is the root system of water hyacinth, drying, pulverize, sieving obtains, the weight content in mold toxin sorbent is 5-50%.
Mold toxin sorbent of the present invention is a solid powder.
Composite mold toxin sorbent provided by the present invention can be used as additive for farm animal feed and uses, and its addition in feed is 0.03%~0.8% of a feed weight.
Composite mold toxin sorbent of the present invention compares with other like product, has tangible beneficial effect: 1, utilize raw mineral materials, microorganism and natural plants to make composite mold toxin sorbent first.2, this prescription combines the adsorption function of three kinds of materials to different mycotoxins, has obtained the wide spectrum absorption property to multiple mycotoxin; Thereby compare with other mold toxin sorbent of the same type, the wide spectrum absorption property is significantly improved.3, first water hyacinth root powder is applied to mold toxin sorbent.The water hyacinth root system has powerful adsorption capacity, and this plantation goods and materials source is abundant.4, water hyacinth is acknowledged as a kind of environment malignant weed, the present invention proposes a kind of new way of water hyacinth is innoxious, recycling, and this utilization and environmental protection to living beings is of great immediate significance.5, product of the present invention is compared with other like product, and is cheap.6, as a kind of composite mold toxin sorbent, its production technology is very easy.
The specific embodiment
Below by specific embodiment the present invention is further described.
The preparation of composite mold toxin sorbent: according to the needed weight content of mold toxin sorbent, take by weighing hydrated aluminosilicate, yeast cell wall respectively, water hyacinth root powder, dry according to a conventional method, the 100-200 order of pulverizing, sieve, physical mixed is even, packing is the composite mold toxin sorbent finished product.
Embodiment 1:
Composition |
Hydrated aluminosilicate |
Yeast cell wall |
Water hyacinth root powder |
Mold toxin sorbent |
Content (%) |
85 |
10 |
5 |
100 |
Embodiment 2:
Composition |
Hydrated aluminosilicate |
Yeast cell wall |
Water hyacinth root powder |
Mold toxin sorbent |
Content (%) |
45 |
5 |
50 |
100 |
Embodiment 3:
Composition |
Hydrated aluminosilicate |
Yeast cell wall |
Water hyacinth root powder |
Mold toxin sorbent |
Content (%) |
15 |
50 |
35 |
100 |
Embodiment 4:
Composition |
Hydrated aluminosilicate |
Yeast cell wall |
Water hyacinth root powder |
Mold toxin sorbent |
Content (%) |
80 |
15 |
5 |
100 |
Embodiment 5:
Composition |
Hydrated aluminosilicate |
Yeast cell wall |
Water hyacinth root powder |
Mold toxin sorbent |
Content (%) |
70 |
20 |
10 |
100 |
The composite mold toxin sorbent that above embodiment is obtained uses as additive for farm animal feed, its addition in feed is 0.03%~0.8% of a feed weight, can effectively reduce the multiple mycotoxin in the feed after the use, acquisition is to the wide spectrum adsorption capacity of multiple mycotoxin, particularly Chinese common mycotoxins such as AFB1, ochratoxin A, zearalenone, zearalenol, vomitoxin there is the good adsorption performance, has improved feed quality and livestock and poultry production performance.
Embodiment 6:
According to the prescription of embodiment 4, promptly the part by weight of hydrated aluminosilicate, yeast cell wall, water hyacinth root powder is 80: 15: 5, makes composite mold toxin sorbent.Press the content of feed weight 0.1%, add in the pig feed that contains the corn that goes mouldy, pig is fed, measure after 7 days, compare with negative control group pig (the normal feed of the no toxin of feeding), the feed intake of pig, daily gain, each index of blood are identical; With the positive control group pig (pig feed of corn of going mouldy of feeding, but do not add this composite mold toxin sorbent) compare, the feed intake of pig, daily gain, each index of blood all are better than positive control group, poisoning symptoms such as no food refusal, vomiting, false heat, and poisoning symptom appears in positive control group.
Embodiment 7:
According to the prescription of embodiment 5, promptly the part by weight of hydrated aluminosilicate, yeast cell wall, water hyacinth root powder is 70: 20: 10, makes composite mold toxin sorbent.Press the content of feed weight 0.1%, add in the broiler fodder that contains go mouldy corn and peanut meal, fryer is fed, measure after 7 days, compare with negative control group fryer (the normal feed of the no toxin of feeding), the feed intake of fryer, daily gain, each index of blood are identical; With the positive control group fryer (broiler fodder of corn of going mouldy of feeding, but do not add this composite mold toxin sorbent) compare, the feed intake of fryer, daily gain, each index of blood all are better than positive control group, no food refusal, poisoning symptom such as One's spirits are drooping, and poisoning symptom appears in positive control group.