CN100384986C - 用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞 - Google Patents

用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞 Download PDF

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CN100384986C
CN100384986C CNB028151445A CN02815144A CN100384986C CN 100384986 C CN100384986 C CN 100384986C CN B028151445 A CNB028151445 A CN B028151445A CN 02815144 A CN02815144 A CN 02815144A CN 100384986 C CN100384986 C CN 100384986C
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cells
cell
neural
neurons
cell population
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CN1630713A (zh
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M·K·卡朋特
J·J·邓汉姆
M·S·因诺库马
S·R·希斯
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ASTERIAS BIOTHERAPY CORP
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Geron Corp
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CNB028151445A 2001-06-21 2002-06-20 用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞 Expired - Fee Related CN100384986C (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US09/888,309 2001-06-21
US09/888,309 US20020019046A1 (en) 2000-01-11 2001-06-21 Direct differentiation of human pluripotent stem cells and characterization of differentiated cells
US10/157,288 2002-05-28
US10/157,288 US7250294B2 (en) 2000-05-17 2002-05-28 Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
PCT/US2002/019477 WO2003000868A1 (en) 2001-06-21 2002-06-20 Dopaminergic neurons and proliferation-competent precursor cells for treating parkinson's disease

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CN2006101013714A Division CN101029302B (zh) 2001-06-21 2002-06-20 用于治疗帕金森病的多巴胺能神经元和具有增殖能力的前体细胞

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CN1630713A CN1630713A (zh) 2005-06-22
CN100384986C true CN100384986C (zh) 2008-04-30

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US (1) US7250294B2 (enExample)
EP (1) EP1404812B1 (enExample)
JP (4) JP4526265B2 (enExample)
KR (2) KR101247037B1 (enExample)
CN (1) CN100384986C (enExample)
AU (1) AU2002322270B2 (enExample)
CA (1) CA2451486C (enExample)
GB (1) GB2393733B (enExample)
IL (2) IL159324A0 (enExample)
WO (1) WO2003000868A1 (enExample)

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US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6667176B1 (en) * 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US20050042749A1 (en) * 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
AU2001263199B2 (en) 2000-05-17 2004-09-16 Asterias Biotherapeutics, Inc. Neural progenitor cell populations
US20030134422A1 (en) * 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US20050090004A1 (en) * 2003-01-16 2005-04-28 Sayre Chauncey B. Stem cell maturation for all tissue lines
US20050170506A1 (en) * 2002-01-16 2005-08-04 Primegen Biotech Llc Therapeutic reprogramming, hybrid stem cells and maturation
CA2488429C (en) * 2002-06-05 2013-05-07 Benjamin Eithan Reubinoff Generation of neural stem cells from undifferentiated human embryonic stem cells
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US20040224302A1 (en) * 2002-07-16 2004-11-11 Thomas Jessel Systems and methods for screening for modulators of neural differentiation
US7632679B2 (en) * 2002-07-16 2009-12-15 The Trustees Of Columbia University In The City Of New York Systems and methods for screening for modulators of neural differentiation
US8293488B2 (en) * 2002-12-09 2012-10-23 Neuralstem, Inc. Method for screening neurogenic agents
EP2457999B1 (en) 2002-12-16 2018-10-17 Technion Research & Development Foundation Ltd. Culture medium for pluripotent stem cells
KR100763477B1 (ko) * 2003-03-12 2007-10-04 리라이언스 라이프 사이언시스 프라이빗. 리미티드 사람 배아 줄기세포로부터 최종적으로 분화된 도파민작용성 뉴런의 유도
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