GB2393733B - Dopaminergic neurons and proliferation-competent precursor cells for treating parkinson's disease - Google Patents

Dopaminergic neurons and proliferation-competent precursor cells for treating parkinson's disease

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Publication number
GB2393733B
GB2393733B GB0400167A GB0400167A GB2393733B GB 2393733 B GB2393733 B GB 2393733B GB 0400167 A GB0400167 A GB 0400167A GB 0400167 A GB0400167 A GB 0400167A GB 2393733 B GB2393733 B GB 2393733B
Authority
GB
United Kingdom
Prior art keywords
proliferation
disease
precursor cells
dopaminergic neurons
treating parkinson
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB0400167A
Other languages
English (en)
Other versions
GB0400167D0 (en
GB2393733A (en
Inventor
Melissa K Carpenter
Jerrod J Denham
Margaret S Inokuma
Scott R Thies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geron Corp
Original Assignee
Geron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/888,309 external-priority patent/US20020019046A1/en
Application filed by Geron Corp filed Critical Geron Corp
Publication of GB0400167D0 publication Critical patent/GB0400167D0/en
Publication of GB2393733A publication Critical patent/GB2393733A/en
Application granted granted Critical
Publication of GB2393733B publication Critical patent/GB2393733B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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GB0400167A 2001-06-21 2002-06-20 Dopaminergic neurons and proliferation-competent precursor cells for treating parkinson's disease Expired - Fee Related GB2393733B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/888,309 US20020019046A1 (en) 2000-01-11 2001-06-21 Direct differentiation of human pluripotent stem cells and characterization of differentiated cells
US10/157,288 US7250294B2 (en) 2000-05-17 2002-05-28 Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
PCT/US2002/019477 WO2003000868A1 (en) 2001-06-21 2002-06-20 Dopaminergic neurons and proliferation-competent precursor cells for treating parkinson's disease

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GB0400167D0 GB0400167D0 (en) 2004-02-11
GB2393733A GB2393733A (en) 2004-04-07
GB2393733B true GB2393733B (en) 2005-09-14

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GB0400167A Expired - Fee Related GB2393733B (en) 2001-06-21 2002-06-20 Dopaminergic neurons and proliferation-competent precursor cells for treating parkinson's disease

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US (1) US7250294B2 (enExample)
EP (1) EP1404812B1 (enExample)
JP (4) JP4526265B2 (enExample)
KR (2) KR101247037B1 (enExample)
CN (1) CN100384986C (enExample)
AU (1) AU2002322270B2 (enExample)
CA (1) CA2451486C (enExample)
GB (1) GB2393733B (enExample)
IL (2) IL159324A0 (enExample)
WO (1) WO2003000868A1 (enExample)

Cited By (3)

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US9018010B2 (en) 2009-11-12 2015-04-28 Technion Research & Development Foundation Limited Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
US9040297B2 (en) 2006-08-02 2015-05-26 Technion Research & Development Foundation Limited Methods of expanding embryonic stem cells in a suspension culture
US9404079B2 (en) 2005-08-29 2016-08-02 Technion Research & Development Foundation Limited Media for culturing stem cells

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GB9518606D0 (en) 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6667176B1 (en) * 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US20050042749A1 (en) * 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
AU2001263199B2 (en) 2000-05-17 2004-09-16 Asterias Biotherapeutics, Inc. Neural progenitor cell populations
US20030134422A1 (en) * 2002-01-16 2003-07-17 Sayre Chauncey Bigelow Stem cell maturation for all tissue lines
US20050090004A1 (en) * 2003-01-16 2005-04-28 Sayre Chauncey B. Stem cell maturation for all tissue lines
US20050170506A1 (en) * 2002-01-16 2005-08-04 Primegen Biotech Llc Therapeutic reprogramming, hybrid stem cells and maturation
CA2488429C (en) * 2002-06-05 2013-05-07 Benjamin Eithan Reubinoff Generation of neural stem cells from undifferentiated human embryonic stem cells
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US20040224302A1 (en) * 2002-07-16 2004-11-11 Thomas Jessel Systems and methods for screening for modulators of neural differentiation
US7632679B2 (en) * 2002-07-16 2009-12-15 The Trustees Of Columbia University In The City Of New York Systems and methods for screening for modulators of neural differentiation
US8293488B2 (en) * 2002-12-09 2012-10-23 Neuralstem, Inc. Method for screening neurogenic agents
EP2457999B1 (en) 2002-12-16 2018-10-17 Technion Research & Development Foundation Ltd. Culture medium for pluripotent stem cells
KR100763477B1 (ko) * 2003-03-12 2007-10-04 리라이언스 라이프 사이언시스 프라이빗. 리미티드 사람 배아 줄기세포로부터 최종적으로 분화된 도파민작용성 뉴런의 유도
ZA200401646B (en) * 2003-03-12 2004-06-07 Reliance Life Sciences Pvt Ltd Derivation of terminally differentiated dopaminergic neurons from human embryonic stem cells.
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