CN100360554C - 肽缀合物 - Google Patents
肽缀合物 Download PDFInfo
- Publication number
- CN100360554C CN100360554C CNB2004800035664A CN200480003566A CN100360554C CN 100360554 C CN100360554 C CN 100360554C CN B2004800035664 A CNB2004800035664 A CN B2004800035664A CN 200480003566 A CN200480003566 A CN 200480003566A CN 100360554 C CN100360554 C CN 100360554C
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- Prior art keywords
- conjugate according
- vesicles
- particulate
- group
- peg
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
样品 | 血小板的SC(%) |
PEG小囊泡H12-PEG小囊泡H12-PEG(PEG)小囊泡 | 9.6±0.915.0±5.017.3±1.9 |
样品 | PAC-1结合(%) | 小囊泡结合(%) |
PBSPEG小囊泡H12-PEG(PEG)小囊泡 | 3.8±0.93.4±0.33.7±0.4 | -1.3±0.71.4±0.6 |
Claims (19)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003029847 | 2003-02-06 | ||
JP029847/2003 | 2003-02-06 | ||
JP017046/2004 | 2004-01-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1747967A CN1747967A (zh) | 2006-03-15 |
CN100360554C true CN100360554C (zh) | 2008-01-09 |
Family
ID=36166966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2004800035664A Expired - Fee Related CN100360554C (zh) | 2003-02-06 | 2004-02-06 | 肽缀合物 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN100360554C (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2011272860A1 (en) * | 2010-06-30 | 2013-02-07 | Brandeis University | Small-molecule-targeted protein degradation |
CN107404921B (zh) * | 2015-03-19 | 2020-12-25 | 雀巢产品有限公司 | 糖-二肽缀合物 |
GB201508014D0 (en) * | 2015-05-11 | 2015-06-24 | Haemostatix Ltd | Haemostatic device |
CN107163134B (zh) * | 2017-06-23 | 2021-03-23 | 广州维奥康药业科技有限公司 | 一种胸腺法新聚乙二醇聚合物、包含其的药物组合物及应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4661471A (en) * | 1984-04-10 | 1987-04-28 | New England Deaconess Hospital | Method of inhibiting and inducing human platelet aggregation |
-
2004
- 2004-02-06 CN CNB2004800035664A patent/CN100360554C/zh not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4661471A (en) * | 1984-04-10 | 1987-04-28 | New England Deaconess Hospital | Method of inhibiting and inducing human platelet aggregation |
Non-Patent Citations (4)
Title |
---|
Antiplatelet "hybrid" peptides analogous to receptorregognition domains on gamma and alpha chains of humanfibrinogen. Timmons S.等.Biochemistry,Vol.28 No.7. 1989 * |
Fibrinogen Ketsugo Albumin Jugotai no KesshobanDaitaibutsu toshite no Kino Hyoka. Yoshuke OKAMURA等.Polymer Preprints,Vol.50 No.5. 2001 * |
Kesshobanmaku Tanpakushitsuo Albumin Jugotai Aruiha RinShiashitsu Kohotai ni Ketsugo Saseta Kesshoban Daitaibutsuno Hyoka. Yuji TERAMURA等.Polymer Preprints,Vol.50 No.14. 2001 * |
Platelet receptor recognition domain on the gamma chain o fhuman fibrinogen and its synthetic peptide analogues. Kloczewiak M. 等.Biochemistry,Vol.28 No.7. 1989 * |
Also Published As
Publication number | Publication date |
---|---|
CN1747967A (zh) | 2006-03-15 |
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C14 | Grant of patent or utility model | ||
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Owner name: LEGAL PERSON OF THE SCHOOL KEIO UNIVERSITY; TANABE Free format text: FORMER NAME OR ADDRESS: LEGAL PERSON OF THE SCHOOL KEIO UNIVERSITY; MITSUBISHI PHARMACEUTICAL CORP. |
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Address after: Tokyo, Japan Co-patentee after: MITSUBISHI TANABE PHARMA Corp. Patentee after: Kelo University Address before: Tokyo, Japan Co-patentee before: MITSUBISHI PHARMA Corp. Patentee before: Kelo University |
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Free format text: FORMER OWNER: MITSUBISHI TANABE PHARMA CORPORATION |
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Free format text: CORRECT: ADDRESS; FROM: TOKYO, JAPAN TO: NO.15-45, MITA 2-CHOME, MINATO-KU, TOKYO, JAPAN |
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CP03 | Change of name, title or address |
Address after: Tokyo, Japan Co-patentee after: MITSUBISHI TANABE PHARMA Corp. Patentee after: Kelo University Address before: Tokyo, Japan Co-patentee before: MITSUBISHI TANABE PHARMA Corp. Patentee before: Kelo University |
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TR01 | Transfer of patent right |
Effective date of registration: 20100617 Address after: Japan Tokyo Mita port 2 chome 15 No. 45 Patentee after: Kelo University Address before: Tokyo, Japan Co-patentee before: MITSUBISHI TANABE PHARMA Corp. Patentee before: Kelo University |
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C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080109 Termination date: 20110206 |