CN100345496C - Heat-stress alleviant for milk-cow, prepn. method and application thereof - Google Patents

Heat-stress alleviant for milk-cow, prepn. method and application thereof Download PDF

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Publication number
CN100345496C
CN100345496C CNB2003101056843A CN200310105684A CN100345496C CN 100345496 C CN100345496 C CN 100345496C CN B2003101056843 A CNB2003101056843 A CN B2003101056843A CN 200310105684 A CN200310105684 A CN 200310105684A CN 100345496 C CN100345496 C CN 100345496C
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vitamin
alleviant
yeast
chromium
carrier
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CNB2003101056843A
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CN1618316A (en
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梁学武
张龙涛
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Fujian Agriculture and Forestry University
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Fujian Agriculture and Forestry University
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Abstract

The present invention relates to a milk cow fodder additive, particularly to a special alleviant for relieving the heat stress reaction generated by a milk cow in a high-temperature summer, a preparation method and an application of the alleviant. A preparation of the present invention comprises components of organic chromium (yeast chromium or Chromium nicotinate) which can be used as fodder, yeast culture (beer yeast or aspergillus oryzae and a base material for the beer yeast or the aspergillus oryzae), nicotinic acid, vitamin A, vitamin D, vitamin E, sodium selenite (or yeast selenium), cupric sulfate, zinc sulphate, cobalt sulfate, calcium iodate, manganese sulphate, potassium chloride (or potassium carbonate), sodium bicarbonate, magnesium oxide, an antioxidant and carriers. The alleviant not only has the advantages of easily obtained raw material source, simple preparation technology and convenient and safe use, but also can effectively relieve the heat stress reaction generated by a milk cow, raise the milk yield and the organism immunizing power of the milk cow, prevent retained afterbirth and rumen acidosis, reduce mastitis generation and raise a conception rate. The present invention has a wide application perspective.

Description

Cow heat stress alleviant and its production and application
Technical field
The present invention relates to a kind of cow feed additive, particularly a kind of alleviant of alleviating the physiological responses to heat stress that milk cow produces at summer high temperature season and its production and application that is exclusively used in.
Background technology
As everyone knows, China is with most countries is the same in the world, and the milk cow of raising mostly is He Sitanniu greatly.Holstein cow is cold-resistant relatively, and To Be Protected from Heat, it compares the adapt circumstance temperature is 10~16 ℃, when temperature rises to (relative humidity is 80%) more than 23 ℃, the feed intake minimizing promptly appears in this kind ox, the output of milk reduces, heat stress symptoms such as reproductive performance obstacle, the milk cow health situation worsens, and then causes a series of health problems such as cud acid poisoning, ketonemia, retained afterbirth.
By nutrition regulation, cow heat stress relief, the existing more research of colleague both at home and abroad.Existing technology mainly is to add rumen-undegraded fat, improves dietary digestibility of energy concentration; Add rumen buffering agents, the minimizing of anti-system because milk cow roughage is searched for food, the fine fodder overfeeding causes the cud acid poisoning; Add Chinese herb feed additive; Improve the daily ration electrolyte concentration; Use vitamin, trace mineral supplement etc.; but the technology of report only limits to certain single nourishing regulate and control technique mostly; and for the milk cow body; adopt single nourishing regulate and control technique to solve the cow heat stress problem, often poor effect (the milk production of cow increase rate is all below 2.30kg) or the output of milk do not had effect.What the present invention adopted for this reason is to utilize entire system nutrition regulation theory and technology, and with the in addition system integration of various nourishing regulate and control techniques, a kind of cow heat stress alleviant of novel practical is developed in comprehensive study.
Summary of the invention
Primary and foremost purpose of the present invention will provide a kind of cow heat stress alleviant and preparation method thereof exactly, next provides the application of cow heat stress alleviant in raising dairy cattle, this product can not only effectively be alleviated the physiological responses to heat stress of milk cow, improve the output of milk and the immunity of organisms of milk cow, prevent retained afterbirth and cud acid poisoning, reduce mastitis, improve conception rate, and raw material sources are easy, and preparation technology is simple, and safety easy to use has no side effect.
Preparation of the present invention comprises Organic Chromium (yeast chromium or nicotinic acid chromium), yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof), nicotinic acid, vitamin A, vitamin D, vitamin E, sodium selenite (or yeast selenium), copper sulphate, zinc sulfate, cobaltous sulfate, calcium iodate, manganese sulfate, potassium chloride (or potash), sodium acid carbonate, magnesia, antioxidant and the carrier that can be used as the feed use.
Described Organic Chromium is yeast chromium or nicotinic acid chromium; Yeast culture is the matrix of brewer's yeast (or aspergillus oryzae) and growth thereof.
Preparation technology's concrete steps of the present invention are as follows:
(1) prepares the A premix of forming by sodium selenite (or yeast selenium), copper sulphate, zinc sulfate, cobaltous sulfate, calcium iodate, manganese sulfate, potassium chloride (or potash), sodium acid carbonate, magnesia and carrier (zeolite powder); A premix formulation: selenium element 16~40mg/kg, copper 400~914mg/kg, zinc element 2057~4342mg/kg, cobalt element 5.7~14.9mg/kg, I 18~45.7mg/kg, manganese element 800~2629mg/kg, potassium chloride (or potash) 229~343g/kg, sodium acid carbonate 217~434g/kg, magnesia 57~171g/kg according to above-mentioned prescription and material purity or content and purpose dosage, calculates and takes by weighing each raw material consumption, then use carrier (zeolite powder) to be assigned to aequum, promptly the difference by purpose dosage and each raw material total amount takes by weighing carrier;
(2) prepare the B premix of forming by Organic Chromium, yeast culture, nicotinic acid, vitamin A, vitamin D, vitamin E, antioxidant (ethoxyquinoline) and carrier (corn protein powder); B premix formulation: chromium element 48~200mg/kg, yeast culture 200~800g/kg, vitamin A 144~3,840,000 IU/kg, vitamin D 32~960,000 IU/kg, vitamin E 8000~22400IU/Kg, nicotinic acid 120~400g/kg, antioxidant (ethoxyquinoline) 0.40~0.80g/kg, according to above-mentioned prescription and material purity or content and purpose dosage, calculate and take by weighing each raw material consumption, then use carrier (corn protein powder) to be assigned to aequum, promptly the difference by purpose dosage and each raw material total amount takes by weighing carrier;
(3) A premix and B premix are packed respectively deposit; In use, with A premix and B premix in 6~8: 1 ratio takes by weighing and mixes and promptly gets cow heat stress alleviant of the present invention.
After formulation preparation is finished, during use the cow heat stress alleviant that makes is sneaked in the cow concentrate in 3~5% ratio, get final product feeding cow.
The alleged cow heat stress alleviant of the present invention is a kind of feed addictive, it is in the summer high temperature phase physiological and biochemical index Changing Pattern that physiological responses to heat stress produced to take place according to milk cow, in comprehensive study milk cow various trace elements under the heat stress condition, vitamin needs amount and Organic Chromium (yeast chromium or nicotinic acid chromium), on the bases of material to the heat stress remission effect such as yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof) and nicotinic acid, utilize entire system nutrition regulation theory and technology, with the system integration in addition of various nourishing regulate and control techniques, thereby a kind of cow heat stress alleviant of novel practical is developed in comprehensive study.
The used chromium element of the present invention is acknowledged as the necessary nutrient of human foods normal glucose metabolism, participates in being made up of trivalent chromium (Cr 3+), the glucose tolerance factor (NRC 2001 dairy cow nutrition needs) formed of niacin, glutamic acid, amion acetic acid and cysteine, under the heat stress situation, can accelerate the speed of utilizing of glucose in the blood, improve the susceptibility of middle insulin of target tissue (as muscle, mammary gland and other immune system) and quasi-insulin growthing factor I, improve immunoglobulin content, reduce rectal temperature, reduce the incidence of disease (Bunting etc., 1994; Mowat, 1993), and product and excreta all meet national nuisanceless standard.The used nicotinic acid of the present invention can improve blood sugar and red blood cell nicotinic acid concentration, and diastole periphery and internal blood vessel to strengthen the transfer of heat from internal organ to skin, make heat turn to external environment by skin.Used yeast culture of the present invention (matrix of brewer's yeast or aspergillus oryzae and growth thereof) can be got rid of the oxygen in the cud, guarantees the anaerobic environment (Dawson, 2001) of cud; When containing Hi CHO in the daily ration, add the growth of yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof) energy stimulating lactic acid bacteria, reduce the cud lactic acid concn, correspondingly regulate ruminal pH value, and the nutriment that contains by yeast secretary and yeast culture itself is to accelerate increasing of cellulose-decomposing bacteria in the cud, promote rumen microorganism quantity to increase and the raising of microbial fermentation ability, thereby improve the production performance Dawson of animal, 1993).
In sum, under the heat stress condition, Organic Chromium (yeast chromium or nicotinic acid chromium), yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof) and nicotinic acid all have the effect of certain alleviation heat stress; Other trace elements: selenium, copper, zinc, iodine, cobalt, manganese and vitamin A, D, E and buffer sodium acid carbonate, magnesia also have extremely important nutrition and physiological action to milk cow.The present invention utilizes entire system nutrition regulation theory and technology; with the system integration in addition of above-mentioned various nourishing regulate and control techniques; both considered to give full play to, excite and utilized milk cow body idiotrophic adjusting function and anti-stress ability; consider the combined effect between the various nourishing regulate and control techniques again, thereby reached the effect of giving full play to various nourishing regulate and control technique global advantages.Thereby the cow heat stress alleviant of making has following remarkable advantage:
(1) can obviously alleviate the physiological responses to heat stress of milk cow, the output of milk increases the 3.06kg/ head. day, improve 17.6% (P<0.01), strengthen body's immunity and premunition, obviously change the physiological status under the body heat stress condition, reduce serum cortisol 50.7%, prevent retained afterbirth and cud acid poisoning, reduce mastitis, improve conception rate;
(2) raw material sources are easy, and preparation technology is simple, and are easy to use, help utilization and extention;
(3) input-output ratio is 1: 8.15, and economic benefit and social benefit are obvious;
(4) the present invention meets national nuisance free feed standard, uses animal product that the present invention produces not have bad residual.
The specific embodiment
Below in conjunction with embodiment preparation of the present invention and application specifically are described below: (embodiments of the invention never only limit to this)
Raw materials used kind and effective element content (or material purity): Organic Chromium (containing chromium 0.1%), yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof), nicotinic acid (purity is 99.5%), vitamin A 500,000 IU/g, vitamin D 500,000 IU/g, vitamin E 500IU/g, sodium selenite (containing selenium 0.5%), copper sulphate (cupric 25%), zinc sulfate (containing zinc 35%), cobaltous sulfate (containing cobalt 1%), calcium iodate (containing iodine 1%), manganese sulfate (containing manganese 31.8%), potassium chloride (purity is 95%), sodium acid carbonate (purity is 95%), magnesia (purity is 94%) and ethoxyquinoline (purity is 66.6%).
Embodiment one:
Take by weighing raw material sodium selenite 12.60kg, copper sulphate 7.20kg, zinc sulfate 19.29kg, cobaltous sulfate 2.70kg, calcium iodate 6.30kg, manganese sulfate 11.32kg, potassium chloride 1005.32kg, sodium acid carbonate 994.74kg, magnesia 498.91kg, carrier (zeolite powder) 591.62kg mix A premix 3150Kg;
Take by weighing raw material Organic Chromium (yeast chromium or nicotinic acid chromium) 27.00kg, yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof) 90.00kg, nicotinic acid 55.00kg, vitamin A 1.80kg, vitamin D 0.30kg, vitamin E 7.20kg, antioxidant (ethoxyquinoline) 0.17kg, carrier (corn protein powder) 268.53kg mix B premix 450.00Kg.
Above-mentioned A premix and B premix packing are deposited, mix in 7: 1 ratio in use, promptly can be made into the cow heat stress alleviant, sneak in the dairy cow diet fine fodder, get final product feeding cow in 3~5% ratio.
The said goods was June 1---and September 1, (humidity-temperature index THI>70) feeding cow was 100, the raising output of milk 17.41% (the 3.06kg/ head. day).
Embodiment two:
Take by weighing sodium selenite 21.6kg, copper sulphate 11.16kg, zinc sulfate 29.57kg, cobaltous sulfate 3.78kg, calcium iodate 12.15kg, manganese sulfate 25.47kg, potassium chloride 1005.32kg, sodium acid carbonate 994.74kg, magnesia 498.91kg, carrier (zeolite powder) 547.30kg mix A premix 3150Kg;
Take by weighing raw material Organic Chromium (yeast chromium or nicotinic acid chromium) 54.00kg, yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof) 225.00kg, nicotinic acid 117.00kg, vitamin A 2.79kg, vitamin D 0.41kg, vitamin E 10.80kg, antioxidant (ethoxyquinoline) 0.17kg, carrier (corn protein powder) 39.83kg mix B premix 450Kg.
All the other preparations and applying step are with embodiment one.
The said goods was June 1---and September 1, (humidity-temperature index THI>70) feeding cow was 100, the raising output of milk 6.26% (the 1.10kg/ head. day).
Embodiment three:
Take by weighing raw material sodium selenite 24.30kg, copper sulphate 9.00kg, zinc sulfate 38.57kg, cobaltous sulfate 4.05kg, calcium iodate 13.50kg, manganese sulfate 25.47kg, potassium chloride 1005.32kg, sodium acid carbonate 994.74kg, magnesia 498.91kg, carrier (zeolite powder) 536.14kg mix A premix 3150Kg;
Take by weighing Organic Chromium (yeast chromium or nicotinic acid chromium) 80.00kg, yeast culture (matrix of brewer's yeast or aspergillus oryzae and growth thereof) 180.00kg, nicotinic acid 144.00kg, vitamin A 3.42kg, vitamin D 0.54kg, vitamin E 12.96kg, antioxidant (ethoxyquinoline) 0.17kg, carrier (corn protein powder) 28.91kg mix B premix 450Kg.
All the other preparations and applying step are with embodiment one.
The said goods was June 1---and September 1, (humidity-temperature index THI>70) feeding cow was 100, the raising output of milk 5% (the 0.88kg/ head. day).
Preparation technology of the present invention is simple, and safe effect easy to use is good, has broad application prospects.

Claims (1)

1, a kind of cow heat stress alleviant, it is characterized in that: this alleviant is the preparation method comprise the steps:
(1) effective ingredient of A premix, weight proportion and preparation: its effective ingredient and weight proportion thereof are selenium element 16~40mg/kg, copper 400~914mg/kg, zinc element 2057~4342mg/kg, cobalt element 5.7~14.9mg/kg, I 18~45.7mg/kg, manganese element 800~2629mg/kg, potassium chloride or potash 229~343g/kg, sodium acid carbonate 217~434g/kg, magnesia 57~171g/kg, carrier is some, described selenium element, copper, the zinc element, cobalt element, I, manganese element is derived from respectively and can be used as the sodium selenite that feed uses, copper sulphate, zinc sulfate, cobaltous sulfate, calcium iodate, manganese sulfate, described carrier is a zeolite powder, according to above-mentioned prescription and material purity or content and purpose dosage, calculate and take by weighing each raw material consumption, be that carrier is assigned to aequum with zeolite powder then, pack is deposited;
(2) effective ingredient of B premix, weight proportion and preparation: its effective ingredient and weight proportion thereof are chromium element 48~200mg/kg, yeast culture 200~800g/kg, nicotinic acid 120~400g/kg, vitamin A 144~3,840,000 IU/kg, vitamin D 32~960,000 IU/kg, vitamin E 8000~22400IU/kg, antioxidant ethoxyquinoline 0.40~0.80g/kg, carrier is some, described chromium element source is from can be used as the yeast chromium that feed uses, described carrier is a corn protein powder, according to above-mentioned prescription and material purity or content and purpose dosage, calculate and take by weighing each raw material consumption, be that carrier is assigned to aequum with corn protein powder then, pack is deposited;
(3) with A premix and B premix in 6~8: 1 ratio takes by weighing, and mixes, and promptly gets cow heat stress alleviant of the present invention.
CNB2003101056843A 2003-11-19 2003-11-19 Heat-stress alleviant for milk-cow, prepn. method and application thereof Expired - Fee Related CN100345496C (en)

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