CN100335034C - Oral cavity cleaning health products containing balsam pear leaf and making method thereof - Google Patents

Oral cavity cleaning health products containing balsam pear leaf and making method thereof Download PDF

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Publication number
CN100335034C
CN100335034C CNB2005100498075A CN200510049807A CN100335034C CN 100335034 C CN100335034 C CN 100335034C CN B2005100498075 A CNB2005100498075 A CN B2005100498075A CN 200510049807 A CN200510049807 A CN 200510049807A CN 100335034 C CN100335034 C CN 100335034C
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China
Prior art keywords
balsam pear
momordicae charantiae
oral
oral cavity
products containing
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Expired - Fee Related
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CNB2005100498075A
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Chinese (zh)
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CN1698577A (en
Inventor
童富淡
汪俏梅
胡家恕
孙海燕
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Zhejiang University ZJU
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Zhejiang University ZJU
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Priority to CNB2005100498075A priority Critical patent/CN100335034C/en
Publication of CN1698577A publication Critical patent/CN1698577A/en
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Publication of CN100335034C publication Critical patent/CN100335034C/en
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  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention discloses a balsam pear leaf type health product for oral cleaning and a making method thereof. Fresh juice is extracted out of mature balsam pear leaves which are already cleaned and dried in the air, and added into toothpaste, collutory, oral cleaning agents or oral gum according to the proportion of 10 to 35% after being condensed. Since balsam pear leaves have the functions of relieving inflammation and removing pathogeneic fire as recorded in Compendium of Materia Medica, the balsam pear leaf extract of the present invention has strong cold and thermal stability and wide pH range of bacteriostasis. The product can effectively inhibit oral pathogenic bacteria and prevent stomatitis, and does not produce any side effect during frequent use.

Description

Leaf of Bitter Gourd Buccal Cavity Cleaned Health Product and Preparation Method
Technical field
The invention belongs to daily cleaning health product and processing technique field thereof, relate to toothpaste, collutory, oral spray, perhaps chewing gum etc. has antibacterial and oral health care product antiinflammation.
Background technology
Oral disease is one of human commonly encountered diseases, is mainly caused by antibacterial or viral infection.World Health Organization (WHO) and the United Nations's oral prophylaxis centre of development statistics show that global oral pathology patient reached 700,000,000 2 thousand ten thousand in 1999, and wherein the patient with severe symptoms is 400,000,000 3 thousand ten thousand, and the death of cancerating is 1,900,000; China is oral disease country occurred frequently, and there were 4,000 ten thousand oral pathology patients in China in 1999, and with 13.27% speed increase.Microorganisms such as antibacterial have not only directly destroyed the barrier protection effect of oral cavity tissue in intraoral existence and breeding, and a large amount of toxin that these microorganisms discharge can impel malignant change of cell, might cause the generation of oral cancer.The prevention of oral disease at present mainly contains two kinds of methods, one is to use antibiotic, patented product-antibiotic CC10232 as U.S. Abbort pharmaceutical factory, it has stronger inhibitory action to gram positive bacterias such as staphylococcus aureus, streptococcus, gargle with 0.01%CC10232, the growth of control dental plaque, the formation that suppresses tartar and elimination gingivitis are had effect preferably.But the life-time service antibiotic can increase drug-resistance of bacteria or make antibacterial imbalance even generation allergy in the body, and some antibiotic produces toxic and side effects in vivo simultaneously, jeopardizes the healthy of people.Two are to use natural active matter, mainly are to add saccharide digestive enzymes such as glucanase, glucoseoxidase in toothpaste, and the viscous polysaccharide substance that the degraded oral cavity bacterium forms is eliminated the bacteria live condition, destroys bacteria cell wall simultaneously, bacteria growing inhibiting.But biological enzyme activity and effect thereof both be subjected to the influence of multiple environmental conditions such as temperature, pH, and prevention effect instability and individual variation are bigger.
The cause of disease complexity of oral diseases such as ulcerative stomatitis, relevant with infection, vitamin deficiency, trace element deficiency and autoimmune function imbalance etc., and there is not specific medicament, often giving treatments such as anti-inflammation, vitimin supplement and trace element clinically, is one of important means of prevention oral disease and use effective oral cavity cleaning health products containing to carry out daily health caring.Purpose of the present invention just provides a kind ofly has the inhibiting bacteria and diminishing inflammation effect unlike the prior art, has no side effect the oral cavity cleaning health protection articles for use that life-time service can not have side effects.
Summary of the invention
The present invention is Main Ingredients and Appearance with the Folium Momordicae Charantiae extract, adds flavorant, flavoring agent and adjuvant, makes toothpaste, collutory, mouth cleaning agent, perhaps makes chewing gum.Contain 10~35% Folium Momordicae Charantiae extract in this oral cavity cleaning health products containing.The manufacture method of above-mentioned Folium Momordicae Charantiae extract is: bright juice, concentration are cleaned, dry, squeezed to the mature leaf of Fructus Momordicae charantiae to 1/5~1/10 of original volume.In the toothpaste base stock, add 15~20% Folium Momordicae Charantiae extract and make toothpaste; In collutory or mouth cleaning agent base stock, add 10~35% Folium Momordicae Charantiae extract and make collutory or mouth cleaning agent; In the chewing gum base stock, add 20~30% Folium Momordicae Charantiae extract and make chewing gum.
Toothpaste of the present invention contains 15~20% Folium Momordicae Charantiae extract, collutory or mouth cleaning agent and contains 10~35% Folium Momordicae Charantiae extract, wherein can add adjuvants such as edible essence, sweeting agent.
Chewing gum of the present invention is made by 20%~30% Folium Momordicae Charantiae extract, edible latex, edible essence, cellulose and flavoring agent etc.
Fructus Momordicae charantiae (Monlordica charantia L.) is the annual climing property herbaceous plant of Cucurbitaceae Momordica, has another name called balsam pear, balsam pear, leprosy Fructus Vitis viniferae and bright and beautiful Fructus Litchi etc., is a kind of medicinal and edible plant.Put down in writing according to Compendium of Material Medica: " Fructus Momordicae charantiae abnormal smells from the patient hardship, cold, nontoxic, have except that pathogenic heat, separate tired, clear away heart-fire make eye bright, the QI invigorating tonifying YANG " etc. effect; " the southern regions of the Yunnan Province book on Chinese herbal medicine " recorded and narrated: Fructus Momordicae charantiae can " rush down the six channels excess-fire, relieve summer heat, QI invigorating be quenched the thirst ", " control red fire-toxin gas, treat malignant boil knot poison ".Fructus Momordicae charantiae not only contains nutrient substance such as protein, carbohydrate, fatty crude fibre, vitamin (Vc content occupy first of the vegetable) and trace element, also has ingredients such as Charantin, Charantin, 5-hydroxy tryptamine, aminobutyric acid, galacturonic acid and pectin.
Folium Momordicae Charantiae can be used as medicine, Compendium of Material Medica record: " leaf dries and is the end, controls all red fire-toxin gas, and incised wound knot poison, sesame furuncle, big furuncle painfully can not be born, gastric qi is ached, GUNTANG, ophthalmalgia, and sub-bitter cold is nontoxic under the Medulla Junci soup, but the QI invigorating tonifying YANG ".Our result of study shows that the hot and cold stability of Folium Momordicae Charantiae extract is strong, and antibacterial pH scope is wide, and minimal inhibitory concentration is low, and has the broad-spectrum antibacterial effect.Based on above-mentioned result of study, correlated product provided by the invention can effectively suppress oral cavity pathogen, the prevention stomatitis; The main component that goods of the present invention use is as the Folium Momordicae Charantiae of Medicine Food Homology, and without any toxic and side effects, often use can not produce any negative effect.
The specific embodiment
Embodiment 1: Folium Momordicae Charantiae toothpaste
Folium Momordicae Charantiae extract 15%~20%, surplus are the toothpaste base stock.
Embodiment 2: the component preferable amount of Folium Momordicae Charantiae toothpaste of the present invention is:
Folium Momordicae Charantiae extract 15~20g sodium carboxymethyl cellulose 10~15g
Glycerol 10~15g sodium lauryl sulphate 10~15g
Calcium bicarbonate 40~50g essence 0.5~1.0g
Distilled water 10~15g saccharin sodium 0.1~0.5g
Embodiment 3: the Folium Momordicae Charantiae collutory
Folium Momordicae Charantiae extract 10%~15%, surplus is a distilled water, adds an amount of essence, fill behind the mixing.
Embodiment 4: the Folium Momordicae Charantiae mouth cleaning agent
Folium Momordicae Charantiae extract 25%~35%, surplus is a distilled water, adds an amount of essence, fill behind the mixing.
Embodiment 5: the Folium Momordicae Charantiae chewing gum
Folium Momordicae Charantiae extract 20%~30%, surplus adds an amount of essence, sweeting agent etc. for edible latex and cellulose.
Compared with the prior art the present invention has the following advantages:
The present invention is with the food and medicament dual-purpose plant---and the leaf of Fructus Momordicae charantiae is a raw material, has no side effect, and cost is low, and the source is abundant, and technology is simple, is a kind of green product.
The embodiments of the invention prescription is reasonable, and the various composition coordinating and unifyings in the raw material are mutually supported, have strengthened the refrigerant anti-inflammatory effect of Folium Momordicae Charantiae extract, and toothpaste color and abnormal smells from the patient are pleasant, through on probation, has the key tooth, prevents and treats dental caries and gingivitis has effect.
The active component that goods of the present invention use is as the Folium Momordicae Charantiae extract of Medicine Food Homology, and without any toxic and side effects, often use can not produce any negative effect, and market potential is big, and application prospect is wide.

Claims (2)

1, a kind of oral cavity cleaning health products containing is characterized in that: it is that the mature leaf of Fructus Momordicae charantiae is through cleaning, dry, squeeze 1/5~1/10 the extract that bright juice is concentrated into the mature leaf original volume that 10~35% composition is arranged in this oral cavity cleaning health products containing.
2, a kind of according to claim 1 oral cavity cleaning health products containing, its manufacture method is: the said extracted thing that adds 15~20% Folium Momordicae Charantiae in the toothpaste base stock is made toothpaste; The said extracted thing that adds 10~35% Folium Momordicae Charantiae in collutory or mouth cleaning agent base stock is made collutory or mouth cleaning agent; The said extracted thing that adds 20~30% Folium Momordicae Charantiae in the chewing gum base stock is made chewing gum.
CNB2005100498075A 2005-05-24 2005-05-24 Oral cavity cleaning health products containing balsam pear leaf and making method thereof Expired - Fee Related CN100335034C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB2005100498075A CN100335034C (en) 2005-05-24 2005-05-24 Oral cavity cleaning health products containing balsam pear leaf and making method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2005100498075A CN100335034C (en) 2005-05-24 2005-05-24 Oral cavity cleaning health products containing balsam pear leaf and making method thereof

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CN1698577A CN1698577A (en) 2005-11-23
CN100335034C true CN100335034C (en) 2007-09-05

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Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103190663A (en) * 2013-04-08 2013-07-10 林华 Balsam pear vine juice
CN104523505A (en) * 2014-12-16 2015-04-22 广西科技大学 Application of bitter gourd root extract in preparation of toothpaste for treating gingiva pain

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
苦瓜叶的抑菌试验 张瑞其等,赣南医学院学报,第23卷第3期 2003 *
苦瓜抑菌防腐作用的实验研究 张绪忠等,预防医学情报杂志,第12卷第1期 1996 *
苦瓜抗菌作用研究 何煜波,食品科学,第19卷第3期 1998 *

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C06 Publication
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C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
EE01 Entry into force of recordation of patent licensing contract

Assignee: Haolai Chemical (Zhongshan) Co., Ltd.

Assignor: Zhejiang University

Contract fulfillment period: 2009.9.10 to 2013.9.10 contract change

Contract record no.: 2008440000534

Denomination of invention: Oral cavity cleaning health products containing balsam pear leaf and making method thereof

Granted publication date: 20070905

License type: Exclusive license

Record date: 20081211

LIC Patent licence contract for exploitation submitted for record

Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2009.9.10 TO 2013.9.10; CHANGE OF CONTRACT

Name of requester: HAOLAI CHEMICAL ENGINEERING (ZHONGSHAN) CO., LTD.

Effective date: 20081211

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20070905

Termination date: 20140524