CL2018000142A1 - Métodos para el tratamiento de trastornos de desarrollo con gaboxadol. - Google Patents
Métodos para el tratamiento de trastornos de desarrollo con gaboxadol.Info
- Publication number
- CL2018000142A1 CL2018000142A1 CL2018000142A CL2018000142A CL2018000142A1 CL 2018000142 A1 CL2018000142 A1 CL 2018000142A1 CL 2018000142 A CL2018000142 A CL 2018000142A CL 2018000142 A CL2018000142 A CL 2018000142A CL 2018000142 A1 CL2018000142 A1 CL 2018000142A1
- Authority
- CL
- Chile
- Prior art keywords
- gaboxadol
- treatment
- syndrome
- developmental disorders
- methods
- Prior art date
Links
- 208000012239 Developmental disease Diseases 0.000 title abstract 3
- ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title abstract 2
- 229950004346 gaboxadol Drugs 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 208000009575 Angelman syndrome Diseases 0.000 abstract 1
- 206010003805 Autism Diseases 0.000 abstract 1
- 208000020706 Autistic disease Diseases 0.000 abstract 1
- 206010008025 Cerebellar ataxia Diseases 0.000 abstract 1
- 208000001914 Fragile X syndrome Diseases 0.000 abstract 1
- 208000006289 Rett Syndrome Diseases 0.000 abstract 1
- 206010044565 Tremor Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000001228 spectrum Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
<p>Uso de 0,05 mg a 30 mg de gaboxadol o su sal farmacéuticamente aceptable para el tratamiento de trastornos del desarrollo tal como síndrome de Angelman, síndrome de X frágil, síndrome de temblor/ataxia relacionado con X frágil, trastorno de espectro autista, autismo, Asperger, trastorno general de desarrollo, trastorno disociativo de la infancia y síndrome de Rett. </p>
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562193717P | 2015-07-17 | 2015-07-17 | |
US201562207595P | 2015-08-20 | 2015-08-20 | |
US201662332567P | 2016-05-06 | 2016-05-06 | |
US201662346763P | 2016-06-07 | 2016-06-07 | |
US15/209,862 US20170014393A1 (en) | 2015-07-17 | 2016-07-14 | Methods of treating developmental disorders with gaboxadol |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2018000142A1 true CL2018000142A1 (es) | 2018-07-13 |
Family
ID=57774846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2018000142A CL2018000142A1 (es) | 2015-07-17 | 2018-01-17 | Métodos para el tratamiento de trastornos de desarrollo con gaboxadol. |
Country Status (16)
Country | Link |
---|---|
US (8) | US20170014393A1 (es) |
EP (1) | EP3324961A4 (es) |
JP (3) | JP2018520189A (es) |
KR (1) | KR20180031721A (es) |
CN (2) | CN108024997A (es) |
AU (2) | AU2016295138B2 (es) |
BR (1) | BR112018000933A2 (es) |
CA (1) | CA2992734A1 (es) |
CL (1) | CL2018000142A1 (es) |
CO (1) | CO2018000375A2 (es) |
HK (1) | HK1250951A1 (es) |
IL (2) | IL256912B2 (es) |
MX (2) | MX2018000745A (es) |
PE (2) | PE20230735A1 (es) |
TW (2) | TWI819995B (es) |
WO (1) | WO2017015049A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
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ES2875742T3 (es) | 2014-06-06 | 2021-11-11 | Ovid Therapeutics Inc | Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman |
US20170014393A1 (en) | 2015-07-17 | 2017-01-19 | Ovid Therapeutics Inc. | Methods of treating developmental disorders with gaboxadol |
KR102518846B1 (ko) | 2016-08-11 | 2023-04-05 | 오비드 테라퓨틱스 인크. | 간질 장애의 치료를 위한 방법 및 조성물 |
US20180140586A1 (en) * | 2016-11-22 | 2018-05-24 | Ovid Therapeutics Inc. | Methods of treating developmental disorders and/or seizure disorders with flupirtine |
US10071083B2 (en) * | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
US20180338959A1 (en) * | 2017-05-24 | 2018-11-29 | Ovid Therapeutics Inc. | Treatment of depressive disorders |
EP3648762A4 (en) | 2017-08-04 | 2021-03-24 | Ovid Therapeutics, Inc. | USE OF GABOXADOL IN THE TREATMENT OF DIABETES AND RELATED DISEASES |
KR20210040358A (ko) | 2018-06-14 | 2021-04-13 | 오비드 테라퓨틱스 인크. | 안젤만 증후군의 치료에서 mir-92a 또는 mir-145의 사용 |
US20210177805A1 (en) * | 2018-08-22 | 2021-06-17 | Ovid Therapeutics Inc. | Use of gaboxadol in the treatment of gastrointestinal tract disorders and asthma |
KR20210062662A (ko) * | 2018-09-20 | 2021-05-31 | 오비드 테라퓨틱스 인크. | 투렛 증후군, 틱들 및 말더듬의 치료를 위한 가복사돌의 사용 |
MX2021005994A (es) * | 2018-11-21 | 2021-09-14 | Certego Therapeutics Inc | Combinacion de gaboxadol y litio para el tratamiento de trastornos psiquiatricos. |
SG11202105358RA (en) | 2018-11-21 | 2021-06-29 | Certego Therapeutics | Gaboxadol for reducing risk of suicide and rapid relief of depression |
MX2021007224A (es) | 2018-12-17 | 2021-09-23 | Ovid Therapeutics Inc | Uso de gaboxadol para el tratamiento del trastorno del sue?o vigilia que no es de 24 horas. |
US20220226268A1 (en) * | 2019-06-07 | 2022-07-21 | Paxmedica, Inc. | Compositions and methods for treating central nervous system disorders |
CA3146737A1 (en) * | 2019-07-15 | 2021-01-21 | Ovid Therapeutics Inc. | Pharmaceutical formulations containing gaboxadol for therapeutic treatment |
JP2023507764A (ja) * | 2019-12-18 | 2023-02-27 | オービッド・セラピューティクス・インコーポレイテッド | 1p36欠失症候群の治療的処置のためのガボキサドール |
IL298334A (en) | 2020-05-20 | 2023-01-01 | Certego Therapeutics Inc | A canceled gaboxadol ring and its use for the treatment of psychiatric disorders |
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ES2875742T3 (es) | 2014-06-06 | 2021-11-11 | Ovid Therapeutics Inc | Métodos para aumentar la inhibición tónica y tratamiento del síndrome de Angelman |
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US20170014393A1 (en) | 2015-07-17 | 2017-01-19 | Ovid Therapeutics Inc. | Methods of treating developmental disorders with gaboxadol |
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KR102518846B1 (ko) | 2016-08-11 | 2023-04-05 | 오비드 테라퓨틱스 인크. | 간질 장애의 치료를 위한 방법 및 조성물 |
US10071083B2 (en) | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
-
2016
- 2016-07-14 US US15/209,862 patent/US20170014393A1/en not_active Abandoned
- 2016-07-14 CN CN201680054308.1A patent/CN108024997A/zh active Pending
- 2016-07-14 WO PCT/US2016/042238 patent/WO2017015049A1/en active Application Filing
- 2016-07-14 CN CN202310549878.XA patent/CN116531370A/zh active Pending
- 2016-07-14 JP JP2018502084A patent/JP2018520189A/ja not_active Withdrawn
- 2016-07-14 BR BR112018000933A patent/BR112018000933A2/pt not_active Application Discontinuation
- 2016-07-14 EP EP16828266.3A patent/EP3324961A4/en active Pending
- 2016-07-14 CA CA2992734A patent/CA2992734A1/en active Pending
- 2016-07-14 PE PE2022002752A patent/PE20230735A1/es unknown
- 2016-07-14 MX MX2018000745A patent/MX2018000745A/es unknown
- 2016-07-14 IL IL256912A patent/IL256912B2/en unknown
- 2016-07-14 KR KR1020187004863A patent/KR20180031721A/ko not_active Application Discontinuation
- 2016-07-14 IL IL305342A patent/IL305342A/en unknown
- 2016-07-14 AU AU2016295138A patent/AU2016295138B2/en active Active
- 2016-07-14 PE PE2018000085A patent/PE20190338A1/es unknown
- 2016-07-15 TW TW105122538A patent/TWI819995B/zh active
- 2016-07-15 TW TW112110413A patent/TW202325293A/zh unknown
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2017
- 2017-12-13 US US15/840,521 patent/US20180098974A1/en not_active Abandoned
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2018
- 2018-01-17 CL CL2018000142A patent/CL2018000142A1/es unknown
- 2018-01-17 MX MX2022004734A patent/MX2022004734A/es unknown
- 2018-01-22 CO CONC2018/0000375A patent/CO2018000375A2/es unknown
- 2018-08-02 US US16/053,343 patent/US20180338960A1/en not_active Abandoned
- 2018-08-15 HK HK18110494.0A patent/HK1250951A1/zh unknown
- 2018-12-17 US US16/221,794 patent/US11096929B2/en active Active
-
2019
- 2019-05-01 US US16/400,227 patent/US20190255027A1/en not_active Abandoned
- 2019-06-25 US US16/451,591 patent/US20190321342A1/en not_active Abandoned
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2020
- 2020-06-25 US US16/911,540 patent/US20210030727A1/en not_active Abandoned
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2021
- 2021-05-25 JP JP2021087584A patent/JP2021130687A/ja active Pending
- 2021-10-12 AU AU2021250862A patent/AU2021250862B2/en active Active
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2022
- 2022-11-04 US US17/981,148 patent/US20230071127A1/en active Pending
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2023
- 2023-05-16 JP JP2023080696A patent/JP2023103375A/ja active Pending
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