EP3324961A4 - Methods of treating developmental disorders with gaboxadol - Google Patents

Methods of treating developmental disorders with gaboxadol Download PDF

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Publication number
EP3324961A4
EP3324961A4 EP16828266.3A EP16828266A EP3324961A4 EP 3324961 A4 EP3324961 A4 EP 3324961A4 EP 16828266 A EP16828266 A EP 16828266A EP 3324961 A4 EP3324961 A4 EP 3324961A4
Authority
EP
European Patent Office
Prior art keywords
gaboxadol
methods
developmental disorders
treating developmental
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
EP16828266.3A
Other languages
German (de)
French (fr)
Other versions
EP3324961A1 (en
Inventor
Matthew During
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ovid Therapeutics Inc
Original Assignee
Ovid Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ovid Therapeutics Inc filed Critical Ovid Therapeutics Inc
Publication of EP3324961A1 publication Critical patent/EP3324961A1/en
Publication of EP3324961A4 publication Critical patent/EP3324961A4/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EP16828266.3A 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol Pending EP3324961A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562193717P 2015-07-17 2015-07-17
US201562207595P 2015-08-20 2015-08-20
US201662332567P 2016-05-06 2016-05-06
US201662346763P 2016-06-07 2016-06-07
PCT/US2016/042238 WO2017015049A1 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol

Publications (2)

Publication Number Publication Date
EP3324961A1 EP3324961A1 (en) 2018-05-30
EP3324961A4 true EP3324961A4 (en) 2019-03-13

Family

ID=57774846

Family Applications (1)

Application Number Title Priority Date Filing Date
EP16828266.3A Pending EP3324961A4 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol

Country Status (16)

Country Link
US (8) US20170014393A1 (en)
EP (1) EP3324961A4 (en)
JP (3) JP2018520189A (en)
KR (1) KR20180031721A (en)
CN (2) CN108024997A (en)
AU (2) AU2016295138B2 (en)
BR (1) BR112018000933A2 (en)
CA (1) CA2992734A1 (en)
CL (1) CL2018000142A1 (en)
CO (1) CO2018000375A2 (en)
HK (1) HK1250951A1 (en)
IL (2) IL305342A (en)
MX (2) MX2018000745A (en)
PE (2) PE20230735A1 (en)
TW (2) TW202325293A (en)
WO (1) WO2017015049A1 (en)

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IL305342A (en) 2015-07-17 2023-10-01 Ovid Therapeutics Inc Methods of treating developmental disorders with gaboxadol
AU2017311412B2 (en) 2016-08-11 2023-05-18 Ovid Therapeutics Inc. Methods and compositions for treatment of epileptic disorders
EP3528807A4 (en) * 2016-11-22 2020-06-17 Ovid Therapeutics Inc Methods of treating developmental disorders and/or seizure disorders with flupirtine
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
US10813918B2 (en) 2017-08-04 2020-10-27 Ovid Therapeutics Inc. Use of Gaboxadol in the treatment of diabetes and related conditions
MX2020013667A (en) 2018-06-14 2021-03-02 Ovid Therapeutics Inc Use of mir-92a or mir-145 in the treatment of angelman syndrome.
CN112888437A (en) * 2018-08-22 2021-06-01 奥维德医疗公司 Use of gaboxadol for treating gastrointestinal disorders and asthma
JP2022501384A (en) 2018-09-20 2022-01-06 オービッド・セラピューティクス・インコーポレイテッドOvid Therapeutics Inc. Use of gaboxador for the treatment of Tourette's syndrome, tics and stuttering
WO2020106927A1 (en) 2018-11-21 2020-05-28 Certego Therapeutics Gaboxadol for reducing risk of suicide and rapid relief of depression
WO2020106976A1 (en) * 2018-11-21 2020-05-28 Certego Therapeutics Combination of gaboxadol and lithium for the treatment of psychiatric disorders
CA3123876A1 (en) 2018-12-17 2020-06-25 Ovid Therapeutics Inc. Use of gaboxadol for the treatment of non-24 hour sleep-wake disorder
CA3142842A1 (en) * 2019-06-07 2020-12-10 Paxmedica, Inc. Compositions and methods for treating central nervous system disorders
KR20220035195A (en) * 2019-07-15 2022-03-21 오비드 테라퓨틱스 인크. Pharmaceutical formulations containing gaboxadol for therapeutic treatment
JP2023507764A (en) * 2019-12-18 2023-02-27 オービッド・セラピューティクス・インコーポレイテッド Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
IL298334A (en) 2020-05-20 2023-01-01 Certego Therapeutics Inc Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders

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EP3372229A1 (en) * 2014-06-06 2018-09-12 Ovid Therapeutics, Inc. Methods of increasing tonic inhibition and treating secondary insomnia

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EP3372229A1 (en) * 2014-06-06 2018-09-12 Ovid Therapeutics, Inc. Methods of increasing tonic inhibition and treating secondary insomnia

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Also Published As

Publication number Publication date
US20230071127A1 (en) 2023-03-09
JP2023103375A (en) 2023-07-26
HK1250951A1 (en) 2019-01-18
US11096929B2 (en) 2021-08-24
US20180338960A1 (en) 2018-11-29
BR112018000933A2 (en) 2018-09-04
WO2017015049A1 (en) 2017-01-26
CN108024997A (en) 2018-05-11
IL256912A (en) 2018-03-29
CO2018000375A2 (en) 2018-04-19
AU2016295138A1 (en) 2018-02-08
PE20230735A1 (en) 2023-05-03
AU2016295138B2 (en) 2021-11-04
KR20180031721A (en) 2018-03-28
TWI819995B (en) 2023-11-01
CL2018000142A1 (en) 2018-07-13
CN116531370A (en) 2023-08-04
US20190117632A1 (en) 2019-04-25
MX2022004734A (en) 2022-05-13
US20170014393A1 (en) 2017-01-19
US20210030727A1 (en) 2021-02-04
JP2018520189A (en) 2018-07-26
US20190255027A1 (en) 2019-08-22
US20190321342A1 (en) 2019-10-24
US20180098974A1 (en) 2018-04-12
JP2021130687A (en) 2021-09-09
PE20190338A1 (en) 2019-03-07
MX2018000745A (en) 2018-08-15
IL305342A (en) 2023-10-01
CA2992734A1 (en) 2017-01-26
TW202325293A (en) 2023-07-01
TW201707700A (en) 2017-03-01
EP3324961A1 (en) 2018-05-30
IL256912B2 (en) 2024-01-01
IL256912B1 (en) 2023-09-01
AU2021250862A1 (en) 2021-11-04
AU2021250862B2 (en) 2023-11-09

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