CL2015000038A1 - Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. - Google Patents

Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Info

Publication number
CL2015000038A1
CL2015000038A1 CL2015000038A CL2015000038A CL2015000038A1 CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1 CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A CL2015000038 A CL 2015000038A CL 2015000038 A1 CL2015000038 A1 CL 2015000038A1
Authority
CL
Chile
Prior art keywords
methods
intermediates
preparing substituted
substituted triazolopyridines
triazolopyridines
Prior art date
Application number
CL2015000038A
Other languages
English (en)
Spanish (es)
Inventor
Volker Schulze Dr
Franz-Josef Mais Dr
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of CL2015000038A1 publication Critical patent/CL2015000038A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CL2015000038A 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios. CL2015000038A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12175640 2012-07-10
EP12185590 2012-09-24
EP13170585 2013-06-05

Publications (1)

Publication Number Publication Date
CL2015000038A1 true CL2015000038A1 (es) 2015-03-13

Family

ID=48793197

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015000038A CL2015000038A1 (es) 2012-07-10 2015-01-08 Métodos para preparar triazolopiridinas sustituidas y compuestos intermediarios.

Country Status (24)

Country Link
US (1) US9388177B2 (enExample)
EP (1) EP2872506A1 (enExample)
JP (1) JP6238979B2 (enExample)
KR (1) KR20150040845A (enExample)
CN (1) CN104603136B (enExample)
AP (1) AP3778A (enExample)
AU (1) AU2013289381A1 (enExample)
BR (1) BR112015000308A2 (enExample)
CA (1) CA2878481A1 (enExample)
CL (1) CL2015000038A1 (enExample)
CO (1) CO7160002A2 (enExample)
CR (1) CR20150006A (enExample)
DO (1) DOP2015000007A (enExample)
EA (1) EA027544B1 (enExample)
HK (1) HK1206731A1 (enExample)
IL (1) IL236265A (enExample)
IN (1) IN2015DN00085A (enExample)
MX (1) MX2015000348A (enExample)
NZ (1) NZ703020A (enExample)
PE (1) PE20150354A1 (enExample)
PH (1) PH12015500061A1 (enExample)
SG (1) SG11201408419QA (enExample)
TN (1) TN2015000008A1 (enExample)
WO (1) WO2014009219A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014195276A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines having activity as mps-1 inhibitors
PT3008062T (pt) * 2013-06-11 2017-06-07 Bayer Pharma AG Derivados de profármaco de triazolopiridinas substituídas
MA38656A1 (fr) 2013-06-11 2018-05-31 Bayer Pharma AG Combinaisons pour le traitement du cancer comprenant un inhibiteur de la kinase mps-1 et un inhibiteur de la mitose
CN107567503B (zh) 2015-04-17 2022-03-22 荷兰转化研究中心有限责任公司 用于ttk抑制剂化疗的预后生物标记
TW201800408A (zh) 2016-06-15 2018-01-01 拜耳製藥公司 Mps-1抑制劑

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JPWO2003030937A1 (ja) * 2001-10-05 2005-01-20 小野薬品工業株式会社 ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤
WO2005110410A2 (en) * 2004-05-14 2005-11-24 Abbott Laboratories Kinase inhibitors as therapeutic agents
UA89503C2 (uk) * 2004-09-13 2010-02-10 Х. Луннбек А/С Заміщені похідні аніліну
US7524860B2 (en) * 2004-10-07 2009-04-28 Pfizer Inc. Antibacterial agents
US20060194823A1 (en) * 2004-12-22 2006-08-31 Georg Kettschau Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
MX2008015747A (es) * 2006-06-06 2008-12-19 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa.
EP1870416A1 (en) * 2006-06-21 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Sulphonamido-macrocycles as tie2 inhibitors
SG174086A1 (en) 2006-08-30 2011-09-29 Cellzome Ltd Triazole derivatives as kinase inhibitors
JO3598B1 (ar) * 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
KR20100049073A (ko) 2007-07-18 2010-05-11 노파르티스 아게 비시클릭 헤테로아릴 화합물 및 키나제 억제제로서의 그의 용도
JP2010536841A (ja) 2007-08-23 2010-12-02 アストラゼネカ アクチボラグ 増殖性疾患治療のためのｔｔｋ／ｍｐｓ１阻害剤としての２−アニリノプリン−８−オン類
JP2010536917A (ja) 2007-08-31 2010-12-02 メルク セローノ ソシエテ アノニム トリアゾロピリジン化合物と、ａｓｋ阻害剤としてのその化合物の利用法
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB0724342D0 (en) * 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
WO2009137322A2 (en) * 2008-05-05 2009-11-12 The Trustees Of The University Of Pennsylvania Processes for the preparation of biphenyl compounds
WO2009155527A2 (en) * 2008-06-19 2009-12-23 Progenics Pharmaceuticals, Inc. Phosphatidylinositol 3 kinase inhibitors
KR20110116160A (ko) 2009-02-13 2011-10-25 포비어 파마수티칼스 카이네이스 저해제로서의 〔1,2,4〕트리아졸로〔1,5-ａ〕피리딘
CN102413831B (zh) 2009-04-29 2014-06-04 拜耳知识产权有限责任公司 取代的咪唑并喹喔啉
WO2010141360A1 (en) * 2009-06-05 2010-12-09 Merck Sharp & Dohme Corp. Biaryl benzotriazole derivatives
MX2011012961A (es) * 2009-06-05 2012-01-30 Cephalon Inc Preparacion y usos de derivados de 1,2,4-triazolo[1,5a]-piridina.
CA2772790C (en) 2009-09-04 2017-06-27 Benjamin Bader Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors
EP2343294A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
EP2343295A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
UY33452A (es) 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
WO2012044567A2 (en) * 2010-09-30 2012-04-05 Merck Sharp & Dohme Corp. Imidazole derivatives
PL2699575T3 (pl) * 2011-04-21 2015-08-31 Bayer Ip Gmbh Triazolopirydyny
WO2012160029A1 (en) * 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk

Also Published As

Publication number Publication date
CA2878481A1 (en) 2014-01-16
AP2014008177A0 (en) 2014-12-31
PH12015500061A1 (en) 2015-03-02
CN104603136B (zh) 2017-06-27
JP2015523372A (ja) 2015-08-13
US9388177B2 (en) 2016-07-12
CR20150006A (es) 2015-02-16
SG11201408419QA (en) 2015-01-29
AP3778A (en) 2016-08-31
DOP2015000007A (es) 2015-02-15
AU2013289381A1 (en) 2015-01-22
PE20150354A1 (es) 2015-03-21
CN104603136A (zh) 2015-05-06
WO2014009219A1 (en) 2014-01-16
US20150148542A1 (en) 2015-05-28
HK1206731A1 (en) 2016-01-15
CO7160002A2 (es) 2015-01-15
KR20150040845A (ko) 2015-04-15
IL236265A0 (en) 2015-02-26
TN2015000008A1 (en) 2016-06-29
JP6238979B2 (ja) 2017-11-29
BR112015000308A2 (pt) 2017-06-27
EP2872506A1 (en) 2015-05-20
IL236265A (en) 2017-07-31
MX2015000348A (es) 2015-04-14
NZ703020A (en) 2017-08-25
EA201590116A1 (ru) 2015-07-30
EA027544B1 (ru) 2017-08-31
IN2015DN00085A (enExample) 2015-05-29

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