CL2010000470A1 - Anticuerpo que se une a efrina-b2 que comprende la region variable de la cadena liviana y pesada bvr-l1, hvr-l2, hvr-h1, hvr-h2 y hvr-h3; polinucleotido que codifica dicho anticuerpo; vector y celula huesped que comprende al polinucleotido; metodo para elaborar el anticuerpo, detectar efrina-b2; y uso de dicho anticuerpo. - Google Patents

Anticuerpo que se une a efrina-b2 que comprende la region variable de la cadena liviana y pesada bvr-l1, hvr-l2, hvr-h1, hvr-h2 y hvr-h3; polinucleotido que codifica dicho anticuerpo; vector y celula huesped que comprende al polinucleotido; metodo para elaborar el anticuerpo, detectar efrina-b2; y uso de dicho anticuerpo.

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Publication number
CL2010000470A1
CL2010000470A1 CL2010000470A CL2010000470A CL2010000470A1 CL 2010000470 A1 CL2010000470 A1 CL 2010000470A1 CL 2010000470 A CL2010000470 A CL 2010000470A CL 2010000470 A CL2010000470 A CL 2010000470A CL 2010000470 A1 CL2010000470 A1 CL 2010000470A1
Authority
CL
Chile
Prior art keywords
hvr
antibody
efrin
polynucleotide
bvr
Prior art date
Application number
CL2010000470A
Other languages
English (en)
Spanish (es)
Inventor
Minhong Yan
Yan Wu
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38656280&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2010000470(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CL2010000470A1 publication Critical patent/CL2010000470A1/es

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • CCHEMISTRY; METALLURGY
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    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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CL2010000470A 2006-01-20 2010-05-11 Anticuerpo que se une a efrina-b2 que comprende la region variable de la cadena liviana y pesada bvr-l1, hvr-l2, hvr-h1, hvr-h2 y hvr-h3; polinucleotido que codifica dicho anticuerpo; vector y celula huesped que comprende al polinucleotido; metodo para elaborar el anticuerpo, detectar efrina-b2; y uso de dicho anticuerpo. CL2010000470A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76089106P 2006-01-20 2006-01-20

Publications (1)

Publication Number Publication Date
CL2010000470A1 true CL2010000470A1 (es) 2010-09-24

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CL2010000470A CL2010000470A1 (es) 2006-01-20 2010-05-11 Anticuerpo que se une a efrina-b2 que comprende la region variable de la cadena liviana y pesada bvr-l1, hvr-l2, hvr-h1, hvr-h2 y hvr-h3; polinucleotido que codifica dicho anticuerpo; vector y celula huesped que comprende al polinucleotido; metodo para elaborar el anticuerpo, detectar efrina-b2; y uso de dicho anticuerpo.

Country Status (18)

Country Link
US (4) US8197815B2 (enExample)
EP (1) EP1976884B1 (enExample)
JP (2) JP5368110B2 (enExample)
KR (2) KR101617108B1 (enExample)
CN (2) CN101410413B (enExample)
AR (1) AR059096A1 (enExample)
AU (1) AU2007243132B2 (enExample)
BR (1) BRPI0706935A2 (enExample)
CA (1) CA2638133A1 (enExample)
CL (1) CL2010000470A1 (enExample)
DK (1) DK1976884T3 (enExample)
IL (3) IL192571A (enExample)
NO (1) NO20083593L (enExample)
RU (1) RU2451031C2 (enExample)
SI (1) SI1976884T1 (enExample)
TW (2) TWI557138B (enExample)
WO (1) WO2007127506A2 (enExample)
ZA (1) ZA200806187B (enExample)

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ZA200806187B (en) 2006-01-20 2009-10-28 Genentech Inc Anti-EphrinB2 antibodies and methods using same
JP2010518115A (ja) * 2007-02-09 2010-05-27 ジェネンテック, インコーポレイテッド 抗Robo4抗体およびそれらのための使用
ES2378976B1 (es) * 2010-09-21 2013-05-06 Fundación Centro Nacional De Investigaciones Oncológicas (Cnio) Anticuerpo contra ephrin b2 y su uso.
AR083819A1 (es) 2010-11-10 2013-03-27 Genentech Inc UN ANTICUERPO QUE SE UNE A BACE1 (ENZIMA 1 DE DISOCIACION DE PROTEINA PRECURSORA DEL AMILOIDE DE SITIO b), METODOS Y COMPOSICIONES PARA INMUNOTERAPIA PARA ENFERMEDAD NEURAL
US20120207743A1 (en) * 2011-02-14 2012-08-16 Allergan, Inc. Inhibiting Aberrant Blood Vessel Formation Using Retargeted Endopeptidases
KR101505157B1 (ko) * 2012-05-08 2015-03-24 주식회사 종근당 항―ErbB2 항체 변이체
EP3221361B1 (en) 2014-11-19 2021-04-21 Genentech, Inc. Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use
JP6859259B2 (ja) 2014-11-19 2021-04-14 ジェネンテック, インコーポレイテッド BACElに対する抗体及び神経疾患免疫療法のためのその使用
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
CN110090295B (zh) * 2018-01-29 2022-12-23 武汉康理通科技有限公司 Ephrin-B1在制备治疗炎症性肠病的药物中的用途
ES2973536T3 (es) 2020-10-21 2024-06-20 Nordex Energy Se & Co Kg Método para calibrar uno o más sensores de carga en una pala de rotor de una turbina eólica

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