CL2009000135A1 - Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios. - Google Patents
Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios.Info
- Publication number
- CL2009000135A1 CL2009000135A1 CL2009000135A CL2009000135A CL2009000135A1 CL 2009000135 A1 CL2009000135 A1 CL 2009000135A1 CL 2009000135 A CL2009000135 A CL 2009000135A CL 2009000135 A CL2009000135 A CL 2009000135A CL 2009000135 A1 CL2009000135 A1 CL 2009000135A1
- Authority
- CL
- Chile
- Prior art keywords
- cataracts
- benzodiazepines
- glaucoma
- cancer
- diseases
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
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Abstract
Compuestos derivados de 1,4-benzodiazepinas; proceso de preparación; composición farmacéutica; y su uso para la profilaxis y el tratamiento de enfermedades, tales como, cataratas, glaucoma, hipertrofia prostática benigna, osteoporosis, dolor, epilepsia, Enfermedad de Parkinson, trastornos gastrointestinales y cáncer entre otras.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN202DE2008 | 2008-01-24 | ||
IN688DE2008 | 2008-03-18 |
Publications (1)
Publication Number | Publication Date |
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CL2009000135A1 true CL2009000135A1 (es) | 2009-10-09 |
Family
ID=40474786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2009000135A CL2009000135A1 (es) | 2008-01-24 | 2009-01-23 | Compuestos derivados de 1,4-benzodiazepinas sustituidas, inhibidores de dipeptidilpeptidasa iv (dpp-iv); composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento de enfermedades tales como diabetes tipo 2, cataratas, glaucoma, hipertrofia prostatica benigna, cancer, entre otras; compuestos intermediarios. |
Country Status (14)
Country | Link |
---|---|
US (1) | US8455479B2 (es) |
EP (1) | EP2250157B1 (es) |
JP (1) | JP5640208B2 (es) |
KR (1) | KR20100113122A (es) |
CN (1) | CN101925586B (es) |
AP (1) | AP2010005364A0 (es) |
AR (1) | AR070520A1 (es) |
AU (1) | AU2009207297B2 (es) |
BR (1) | BRPI0906705A2 (es) |
CA (1) | CA2712685A1 (es) |
CL (1) | CL2009000135A1 (es) |
EA (1) | EA018612B1 (es) |
PE (1) | PE20091353A1 (es) |
WO (1) | WO2009093269A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2011107494A1 (de) | 2010-03-03 | 2011-09-09 | Sanofi | Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8492376B2 (en) * | 2010-04-21 | 2013-07-23 | Hoffmann-La Roche Inc. | Heteroaryl-cyclohexyl-tetraazabenzo[e]azulenes |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
IN2010DE02164A (es) | 2010-09-13 | 2015-07-24 | Panacea Biotec Ltd | |
CN102617566B (zh) * | 2011-01-30 | 2015-03-04 | 山东轩竹医药科技有限公司 | 吡啶并咪唑烷衍生物 |
CN102241678B (zh) * | 2011-04-26 | 2014-10-29 | 辽宁利锋科技开发有限公司 | 含有脂环结构化合物的抗肿瘤作用与应用 |
CN104230935A (zh) * | 2011-04-26 | 2014-12-24 | 辽宁利锋科技开发有限公司 | 含有脂环结构化合物的抗肿瘤作用与应用 |
WO2013037390A1 (en) | 2011-09-12 | 2013-03-21 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
WO2013045413A1 (en) | 2011-09-27 | 2013-04-04 | Sanofi | 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors |
US20150297573A1 (en) | 2012-10-24 | 2015-10-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | TPL2 KINASE INHIBITORS FOR PREVENTING OR TREATING DIABETES AND FOR PROMOTING Beta-CELL SURVIVAL |
KR20160028241A (ko) | 2014-09-03 | 2016-03-11 | 김형도 | 목욕탕용 순환배관 슬러지 제거방법 |
ES2805743T3 (es) | 2015-03-24 | 2021-02-15 | Inst Nat Sante Rech Med | Método y composición farmacéutica para uso en el tratamiento de la diabetes |
CA3014644A1 (en) * | 2016-02-15 | 2017-08-24 | The Regents Of The University Of Michigan | Fused 1,4-oxazepines and related analogs as bet bromodomain inhibitors |
CN106883152A (zh) * | 2017-04-07 | 2017-06-23 | 上海应用技术大学 | 一种β‑氨基酮的制备方法 |
CN108084187A (zh) * | 2017-12-15 | 2018-05-29 | 宜昌人福药业有限责任公司 | 苯并二氮杂*类氢化物 |
AR124008A1 (es) | 2020-11-06 | 2023-02-01 | Cytokinetics Inc | 1,4-diazepanonas bicíclicas y sus usos terapéuticos |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA74912C2 (en) | 2001-07-06 | 2006-02-15 | Merck & Co Inc | Beta-aminotetrahydroimidazo-(1,2-a)-pyrazines and tetratriazolo-(4,3-a)-pyrazines as inhibitors of dipeptylpeptidase for the treatment or prevention of diabetes |
WO2004007468A1 (en) * | 2002-07-15 | 2004-01-22 | Merck & Co., Inc. | Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes |
EP1554280B1 (en) * | 2002-10-07 | 2007-08-15 | Merck & Co., Inc. | Antidiabetic beta-amino heterocyclic dipeptidyl peptidase inhibitors |
EP1556362B1 (en) * | 2002-10-18 | 2008-03-26 | Merck & Co., Inc. | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
WO2004058266A1 (en) | 2002-12-20 | 2004-07-15 | Merck & Co., Inc. | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
ATE447574T1 (de) * | 2003-05-14 | 2009-11-15 | Merck & Co Inc | 3-amino-4-phenylbutansäurederivate als dipeptidylpeptidase-hemmer zur behandlung oder vorbeugung von diabetes |
JP2007500704A (ja) * | 2003-07-31 | 2007-01-18 | メルク エンド カムパニー インコーポレーテッド | 糖尿病の治療又は予防のためのジペプチジルペプチダーゼiv−阻害剤としてのヘキサヒドロジアゼピノン |
US20090156465A1 (en) * | 2005-12-30 | 2009-06-18 | Sattigeri Jitendra A | Derivatives of beta-amino acid as dipeptidyl peptidase-iv inhibitors |
-
2009
- 2009-01-23 EA EA201070864A patent/EA018612B1/ru not_active IP Right Cessation
- 2009-01-23 PE PE2009000101A patent/PE20091353A1/es not_active Application Discontinuation
- 2009-01-23 CN CN200980103148.5A patent/CN101925586B/zh not_active Expired - Fee Related
- 2009-01-23 AU AU2009207297A patent/AU2009207297B2/en not_active Ceased
- 2009-01-23 US US12/863,016 patent/US8455479B2/en active Active
- 2009-01-23 CA CA2712685A patent/CA2712685A1/en not_active Abandoned
- 2009-01-23 CL CL2009000135A patent/CL2009000135A1/es unknown
- 2009-01-23 BR BRPI0906705-1A patent/BRPI0906705A2/pt not_active IP Right Cessation
- 2009-01-23 EP EP09703708.9A patent/EP2250157B1/en not_active Not-in-force
- 2009-01-23 JP JP2010543630A patent/JP5640208B2/ja not_active Expired - Fee Related
- 2009-01-23 AP AP2010005364A patent/AP2010005364A0/en unknown
- 2009-01-23 KR KR1020107018056A patent/KR20100113122A/ko not_active Application Discontinuation
- 2009-01-23 WO PCT/IN2009/000061 patent/WO2009093269A1/en active Application Filing
- 2009-01-26 AR ARP090100236A patent/AR070520A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP5640208B2 (ja) | 2014-12-17 |
AU2009207297B2 (en) | 2011-11-10 |
BRPI0906705A2 (pt) | 2015-06-30 |
CN101925586A (zh) | 2010-12-22 |
AR070520A1 (es) | 2010-04-14 |
EP2250157A1 (en) | 2010-11-17 |
EA018612B1 (ru) | 2013-09-30 |
US20100311732A1 (en) | 2010-12-09 |
PE20091353A1 (es) | 2009-09-05 |
EP2250157B1 (en) | 2014-11-05 |
KR20100113122A (ko) | 2010-10-20 |
WO2009093269A1 (en) | 2009-07-30 |
CA2712685A1 (en) | 2009-07-30 |
JP2011510068A (ja) | 2011-03-31 |
CN101925586B (zh) | 2014-05-07 |
WO2009093269A9 (en) | 2009-10-15 |
AU2009207297A1 (en) | 2009-07-30 |
US8455479B2 (en) | 2013-06-04 |
EA201070864A1 (ru) | 2011-02-28 |
AP2010005364A0 (en) | 2010-08-31 |
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