CL2007001911A1 - Uso de un componente neurotoxico de un complejo de toxina de clostridium botulinum, en donde la composicion carece de cualquier otro componente proteico del complejo para tratar una afeccion asociada con la inervacion colinergica muscular hiperactiva - Google Patents
Uso de un componente neurotoxico de un complejo de toxina de clostridium botulinum, en donde la composicion carece de cualquier otro componente proteico del complejo para tratar una afeccion asociada con la inervacion colinergica muscular hiperactivaInfo
- Publication number
- CL2007001911A1 CL2007001911A1 CL200701911A CL2007001911A CL2007001911A1 CL 2007001911 A1 CL2007001911 A1 CL 2007001911A1 CL 200701911 A CL200701911 A CL 200701911A CL 2007001911 A CL2007001911 A CL 2007001911A CL 2007001911 A1 CL2007001911 A1 CL 2007001911A1
- Authority
- CL
- Chile
- Prior art keywords
- complex
- component
- hypercular
- inervation
- affection
- Prior art date
Links
- 108030001720 Bontoxilysin Proteins 0.000 title 1
- 241000193155 Clostridium botulinum Species 0.000 title 1
- 229940053031 botulinum toxin Drugs 0.000 title 1
- 230000003387 muscular Effects 0.000 title 1
- 231100000189 neurotoxic Toxicity 0.000 title 1
- 230000002887 neurotoxic effect Effects 0.000 title 1
- 235000004252 protein component Nutrition 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81775606P | 2006-06-29 | 2006-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2007001911A1 true CL2007001911A1 (es) | 2008-03-14 |
Family
ID=38462381
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL200701911A CL2007001911A1 (es) | 2006-06-29 | 2007-06-28 | Uso de un componente neurotoxico de un complejo de toxina de clostridium botulinum, en donde la composicion carece de cualquier otro componente proteico del complejo para tratar una afeccion asociada con la inervacion colinergica muscular hiperactiva |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US8557255B2 (OSRAM) |
| EP (2) | EP2032157A1 (OSRAM) |
| JP (2) | JP5897784B2 (OSRAM) |
| KR (3) | KR20150126979A (OSRAM) |
| CN (1) | CN101460190A (OSRAM) |
| AR (1) | AR061669A1 (OSRAM) |
| AU (1) | AU2007264008B2 (OSRAM) |
| BR (1) | BRPI0713061A2 (OSRAM) |
| CA (1) | CA2654214C (OSRAM) |
| CL (1) | CL2007001911A1 (OSRAM) |
| IL (1) | IL195201A (OSRAM) |
| MX (1) | MX2009000253A (OSRAM) |
| RU (1) | RU2453333C2 (OSRAM) |
| TW (1) | TWI519310B (OSRAM) |
| UY (1) | UY30450A1 (OSRAM) |
| WO (1) | WO2008000490A1 (OSRAM) |
| ZA (1) | ZA200808491B (OSRAM) |
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| AR061669A1 (es) * | 2006-06-29 | 2008-09-10 | Merz Pharma Gmbh & Co Kgaa | Aplicacion de alta frecuencia de terapia con toxina botulinica |
| US10792344B2 (en) * | 2006-06-29 | 2020-10-06 | Merz Pharma Gmbh & Co. Kgaa | High frequency application of botulinum toxin therapy |
| EP1985276A1 (en) * | 2007-04-26 | 2008-10-29 | Merz Pharma GmbH & Co. KGaA | Treatment of movement disorders by a combined use of a chemodenervating agent and automated movement therapy |
| BRPI0812245A2 (pt) * | 2007-06-01 | 2014-10-21 | Merz Pharma Gmbh & Co Kgaa | Método para provisão de um relaxante muscular termoestável com base no componente neurotóxico da toxina botulínica na forma sólida |
| US7473429B1 (en) * | 2007-07-27 | 2009-01-06 | Renfroe J Ben | Method for treatment of laminitis in animals |
| US8455459B2 (en) * | 2007-08-02 | 2013-06-04 | Medicis Pharmaceutical Corporation | Method of applying an injectable filler |
| US20090204101A1 (en) * | 2007-08-20 | 2009-08-13 | Wortzman Mitchell S | Method of applying an injectable filler |
| US9161970B2 (en) | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
| US9044477B2 (en) * | 2007-12-12 | 2015-06-02 | Allergan, Inc. | Botulinum toxin formulation |
| EP2072039A1 (en) * | 2007-12-21 | 2009-06-24 | Merz Pharma GmbH & Co.KGaA | Use of a neurotoxic component of Clostridium botulinum toxin complex to reduce or prevent side effects |
| EP2072057A1 (en) | 2007-12-21 | 2009-06-24 | Merz Pharma GmbH & Co.KGaA | Early administration of Botulinum toxin in the treatment of cerebrovascular event and spinal cord injury |
| ES2571792T3 (es) * | 2008-03-31 | 2016-05-26 | The Chemo-Sero-Therapeutic Res Inst | Neurotoxina botulínica A2 para su uso en el tratamiento de la hiperactividad muscular en presencia de anticuerpos neutralizantes de tipo A1 |
| MX2011001823A (es) | 2008-08-29 | 2011-03-25 | Merz Pharma Gmbh & Co Kgaa | Neurotoxinas clostridiales con persistencia alterada. |
| EP2161033B1 (en) | 2008-09-09 | 2013-05-01 | Susanne Dr. Grafe | Botulinum toxin to introduce temporal infertiliy in a vertebrate (e.g. human) |
| EP2248518B1 (en) * | 2009-04-17 | 2013-01-16 | Merz Pharma GmbH & Co. KGaA | Formulation for stabilizing proteins, peptides or mixtures thereof. |
| EP2246065A1 (en) | 2009-04-29 | 2010-11-03 | Merz Pharma GmbH & Co. KGaA | Intrastriatal botulinum toxin therapy |
| WO2011023213A1 (en) * | 2009-08-28 | 2011-03-03 | Merz Pharma Gmbh & Co. Kgaa | Modified chemodenervating agents |
| SMT201800487T1 (it) * | 2009-10-21 | 2019-01-11 | Revance Therapeutics Inc | Metodi e sistemi per purificare neurotossina botulinica non complessata |
| KR101134146B1 (ko) | 2010-05-31 | 2012-04-19 | 메덱스젠 주식회사 | 국소 근마비 효과를 갖는 비확산형 보툴리눔 독소와 그의 정제방법 |
| EP2399601A1 (en) | 2010-06-24 | 2011-12-28 | Merz Pharma GmbH & Co. KGaA | Botulinum toxin therapy |
| CA2814054A1 (en) | 2010-10-12 | 2012-04-19 | Merz Pharma Gmbh & Co. Kgaa | Formulation suitable for stabilizing proteins, which is free of mammalian excipients |
| RU2454170C1 (ru) * | 2011-02-21 | 2012-06-27 | Федеральное государственное учреждение "Нижегородский научно-исследовательский институт травматологии и ортопедии" Министерства здравоохранения и социального развития Российской Федерации | Способ лечения спастичности мышц у больных с позвоночно-спинномозговой травмой |
| US20140120077A1 (en) | 2012-10-28 | 2014-05-01 | Revance Therapeutics, Inc. | Compositions and Methods for Safe Treatment of Rhinitis |
| RU2535115C1 (ru) | 2013-05-15 | 2014-12-10 | Бости Трейдинг Лтд | Фармацевтический состав, содержащий нейротоксин ботулина |
| CA2918233C (en) * | 2013-07-30 | 2022-08-30 | Merz Pharma Gmbh & Co. Kgaa | Process for preparing a highly pure neurotoxic component of a botulinum toxin and uses thereof |
| WO2015039206A1 (en) * | 2013-09-20 | 2015-03-26 | Mddt Inc. | Diagnosing and treating movement disorders |
| US10231665B2 (en) | 2013-09-20 | 2019-03-19 | Mddt Inc. | Diagnosing and treating movement disorders |
| EP3154635A1 (en) * | 2014-06-13 | 2017-04-19 | Merz Pharma GmbH & Co. KGaA | Novel uses of recombinant clostridial neurotoxins with decreased duration of effect |
| EP3154572A1 (en) * | 2014-06-13 | 2017-04-19 | Merz Pharma GmbH & Co. KGaA | Novel uses of recombinant clostridial neurotoxins with decreased duration of effect |
| US11484580B2 (en) | 2014-07-18 | 2022-11-01 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| EP3285800B1 (en) * | 2015-04-24 | 2019-09-18 | Consiglio Nazionale Delle Ricerche | A new therapeutic use of the botulinum neurotoxin serotype a |
| US11602303B2 (en) * | 2017-02-10 | 2023-03-14 | Mauricio De Maio Domingos | Methods and systems for preventing, correcting, transforming, and modifying facial, aesthetics, and consulting patients regarding the same |
| US20220143157A1 (en) * | 2019-02-21 | 2022-05-12 | Merz Pharma Gmbh & Co. Kgaa | Novel uses of botulinum neurotoxin for the treatment of tremor |
| RU2721300C2 (ru) * | 2019-10-17 | 2020-05-18 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр радиологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ радиологии" Минздрава России) | Способ лечения нейрогенной дисфункции мочевого пузыря, проявляющейся функциональной инфравезикальной обструкцией у женщин |
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| US10960061B1 (en) | 2019-10-18 | 2021-03-30 | Penland Foundation | Treatment of amyotrophic lateral sclerosis using botulinum toxin |
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| EP4045073A4 (en) | 2019-10-18 | 2022-12-07 | Penland Foundation | Botulinum toxin for use in treatment |
| US10973873B1 (en) | 2019-10-18 | 2021-04-13 | Penland Foundation | Treatment of asthma using botulinum toxin |
| US10960060B1 (en) | 2019-10-18 | 2021-03-30 | Penland Foundation | Treatment of cardiac arrhythmia using botulinum toxin |
| US11090371B1 (en) | 2019-10-18 | 2021-08-17 | Penland Foundation | Treatment of cirrhosis using botulinum toxin |
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| BRPI0812245A2 (pt) * | 2007-06-01 | 2014-10-21 | Merz Pharma Gmbh & Co Kgaa | Método para provisão de um relaxante muscular termoestável com base no componente neurotóxico da toxina botulínica na forma sólida |
| US8586081B2 (en) * | 2007-09-20 | 2013-11-19 | University Of Massachusetts | Detoxified recombinant botulinum neurotoxin |
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-
2007
- 2007-06-27 AR ARP070102861A patent/AR061669A1/es unknown
- 2007-06-28 CL CL200701911A patent/CL2007001911A1/es unknown
- 2007-06-28 MX MX2009000253A patent/MX2009000253A/es active IP Right Grant
- 2007-06-28 WO PCT/EP2007/005754 patent/WO2008000490A1/en not_active Ceased
- 2007-06-28 CA CA2654214A patent/CA2654214C/en active Active
- 2007-06-28 AU AU2007264008A patent/AU2007264008B2/en active Active
- 2007-06-28 UY UY30450A patent/UY30450A1/es not_active Application Discontinuation
- 2007-06-28 TW TW096123534A patent/TWI519310B/zh active
- 2007-06-28 CN CNA2007800206820A patent/CN101460190A/zh active Pending
- 2007-06-28 KR KR1020157031398A patent/KR20150126979A/ko not_active Ceased
- 2007-06-28 BR BRPI0713061-9A patent/BRPI0713061A2/pt not_active IP Right Cessation
- 2007-06-28 EP EP07764931A patent/EP2032157A1/en not_active Ceased
- 2007-06-28 EP EP12001562A patent/EP2484373A1/en not_active Withdrawn
- 2007-06-28 KR KR1020147032748A patent/KR20140142377A/ko not_active Ceased
- 2007-06-28 RU RU2009102848/15A patent/RU2453333C2/ru active
- 2007-06-28 JP JP2009517002A patent/JP5897784B2/ja active Active
- 2007-06-28 KR KR1020097001114A patent/KR20090027732A/ko not_active Ceased
- 2007-06-29 US US11/824,393 patent/US8557255B2/en active Active
-
2008
- 2008-10-06 ZA ZA200808491A patent/ZA200808491B/xx unknown
- 2008-11-10 IL IL195201A patent/IL195201A/en active IP Right Grant
-
2013
- 2013-09-13 US US14/026,289 patent/US9095523B2/en active Active
- 2013-09-27 JP JP2013201656A patent/JP2014015476A/ja not_active Withdrawn
-
2015
- 2015-06-25 US US14/749,834 patent/US9572871B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007264008A1 (en) | 2008-01-03 |
| AR061669A1 (es) | 2008-09-10 |
| AU2007264008B2 (en) | 2012-06-28 |
| MX2009000253A (es) | 2009-01-22 |
| ZA200808491B (en) | 2009-11-25 |
| US9572871B2 (en) | 2017-02-21 |
| BRPI0713061A2 (pt) | 2012-04-10 |
| KR20150126979A (ko) | 2015-11-13 |
| US20140010803A1 (en) | 2014-01-09 |
| US8557255B2 (en) | 2013-10-15 |
| TW200819140A (en) | 2008-05-01 |
| IL195201A (en) | 2015-11-30 |
| RU2453333C2 (ru) | 2012-06-20 |
| RU2009102848A (ru) | 2010-08-10 |
| UY30450A1 (es) | 2009-04-30 |
| CA2654214A1 (en) | 2008-01-03 |
| KR20090027732A (ko) | 2009-03-17 |
| US9095523B2 (en) | 2015-08-04 |
| KR20140142377A (ko) | 2014-12-11 |
| EP2032157A1 (en) | 2009-03-11 |
| US20080003241A1 (en) | 2008-01-03 |
| EP2484373A1 (en) | 2012-08-08 |
| JP2009541396A (ja) | 2009-11-26 |
| CA2654214C (en) | 2023-07-04 |
| TWI519310B (zh) | 2016-02-01 |
| CN101460190A (zh) | 2009-06-17 |
| US20150290303A1 (en) | 2015-10-15 |
| WO2008000490A1 (en) | 2008-01-03 |
| IL195201A0 (en) | 2009-08-03 |
| JP2014015476A (ja) | 2014-01-30 |
| JP5897784B2 (ja) | 2016-03-30 |
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