ES2571792T3 - Neurotoxina botulínica A2 para su uso en el tratamiento de la hiperactividad muscular en presencia de anticuerpos neutralizantes de tipo A1 - Google Patents
Neurotoxina botulínica A2 para su uso en el tratamiento de la hiperactividad muscular en presencia de anticuerpos neutralizantes de tipo A1Info
- Publication number
- ES2571792T3 ES2571792T3 ES09726893T ES09726893T ES2571792T3 ES 2571792 T3 ES2571792 T3 ES 2571792T3 ES 09726893 T ES09726893 T ES 09726893T ES 09726893 T ES09726893 T ES 09726893T ES 2571792 T3 ES2571792 T3 ES 2571792T3
- Authority
- ES
- Spain
- Prior art keywords
- type
- treatment
- neutralizing antibodies
- botulinum neurotoxin
- muscle hyperactivity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un medicamento que comprende como ingrediente activo la neurotoxina de tipo A de 150 kDa de Clostridium botulinum de tipo A2 (NTX A2) para su uso en el tratamiento de una enfermedad con hiperactividad muscular para su uso en un paciente que tiene un anticuerpo neutralizante frente a una toxina botulínica de tipo A1.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2008092145 | 2008-03-31 | ||
PCT/JP2009/056613 WO2009123174A1 (ja) | 2008-03-31 | 2009-03-31 | A2型ボツリヌス神経毒素製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2571792T3 true ES2571792T3 (es) | 2016-05-26 |
Family
ID=41135546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09726893T Active ES2571792T3 (es) | 2008-03-31 | 2009-03-31 | Neurotoxina botulínica A2 para su uso en el tratamiento de la hiperactividad muscular en presencia de anticuerpos neutralizantes de tipo A1 |
Country Status (5)
Country | Link |
---|---|
US (2) | US20110033431A1 (es) |
EP (1) | EP2283849B1 (es) |
JP (1) | JPWO2009123174A1 (es) |
ES (1) | ES2571792T3 (es) |
WO (1) | WO2009123174A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9278133B2 (en) * | 2006-10-27 | 2016-03-08 | The Chemo-Sero-Therapeutic Research Institute | Highly purified type A botulinum toxin preparation from infant botulism pathogen |
US20110033431A1 (en) * | 2008-03-31 | 2011-02-10 | The Chemo-Sero-Therapeutic Research Institute | Type a2 botulinum toxin preparation |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE122009000066I2 (de) * | 1993-06-10 | 2010-12-30 | Allergan Inc | Behandlung von neuromuskulären Störungen und Zuständen mit verschiedenen botulinen Serotypen |
US5512547A (en) | 1994-10-13 | 1996-04-30 | Wisconsin Alumni Research Foundation | Pharmaceutical composition of botulinum neurotoxin and method of preparation |
US5756468A (en) | 1994-10-13 | 1998-05-26 | Wisconsin Alumni Research Foundation | Pharmaceutical compositions of botulinum toxin or botulinum neurotoxin and methods of preparation |
DE19925739A1 (de) * | 1999-06-07 | 2000-12-21 | Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh | Therapeutikum mit einem Botulinum-Neurotoxin |
JPWO2003082315A1 (ja) * | 2002-03-29 | 2005-07-28 | 財団法人化学及血清療法研究所 | 筋緊張亢進疾患治療剤 |
WO2004112821A1 (ja) * | 2003-06-20 | 2004-12-29 | Santen Pharmaceutical Co., Ltd. | 筋緊張亢進性疾患の治療剤 |
WO2007125604A1 (ja) | 2006-04-28 | 2007-11-08 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | 神経毒素の定量方法 |
AR061669A1 (es) * | 2006-06-29 | 2008-09-10 | Merz Pharma Gmbh & Co Kgaa | Aplicacion de alta frecuencia de terapia con toxina botulinica |
US9278133B2 (en) * | 2006-10-27 | 2016-03-08 | The Chemo-Sero-Therapeutic Research Institute | Highly purified type A botulinum toxin preparation from infant botulism pathogen |
US8540987B2 (en) * | 2008-01-29 | 2013-09-24 | Institute For Antibodies Co., Ltd. | Composition for neutralizing botulinus toxin type-A, and human anti-botulinus toxin type-A antibody |
US20110033431A1 (en) * | 2008-03-31 | 2011-02-10 | The Chemo-Sero-Therapeutic Research Institute | Type a2 botulinum toxin preparation |
WO2012047427A2 (en) * | 2010-08-31 | 2012-04-12 | The Regents Of The University Of California | Antibodies for botulinum neurotoxins |
-
2009
- 2009-03-31 US US12/935,769 patent/US20110033431A1/en not_active Abandoned
- 2009-03-31 ES ES09726893T patent/ES2571792T3/es active Active
- 2009-03-31 WO PCT/JP2009/056613 patent/WO2009123174A1/ja active Application Filing
- 2009-03-31 EP EP09726893.2A patent/EP2283849B1/en not_active Not-in-force
- 2009-03-31 JP JP2010505929A patent/JPWO2009123174A1/ja active Pending
-
2013
- 2013-05-28 US US13/903,731 patent/US9623075B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2009123174A1 (ja) | 2009-10-08 |
US20130252902A1 (en) | 2013-09-26 |
EP2283849B1 (en) | 2016-05-04 |
US20110033431A1 (en) | 2011-02-10 |
US9623075B2 (en) | 2017-04-18 |
EP2283849A4 (en) | 2013-04-10 |
JPWO2009123174A1 (ja) | 2011-07-28 |
EP2283849A1 (en) | 2011-02-16 |
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