CH717634A2 - Composition for topical application, for moisturizing the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation. - Google Patents

Composition for topical application, for moisturizing the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation. Download PDF

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Publication number
CH717634A2
CH717634A2 CH70351/21A CH0703512021A CH717634A2 CH 717634 A2 CH717634 A2 CH 717634A2 CH 70351/21 A CH70351/21 A CH 70351/21A CH 0703512021 A CH0703512021 A CH 0703512021A CH 717634 A2 CH717634 A2 CH 717634A2
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Prior art keywords
composition according
composition
skin
mixture
glycerin
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CH70351/21A
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French (fr)
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Tenaille Bruno
Tenaille Isabelle
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Tenaille Bruno
Tenaille Isabelle
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Priority to CH70351/21A priority Critical patent/CH717634A2/en
Publication of CH717634A2 publication Critical patent/CH717634A2/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/06Emulsions
    • A61K8/062Oil-in-water emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

On décrit une composition pour application topique, à visée hydratante pour la peau du diabétique, dans le but de favoriser une diminution de la perte d'hydratation et du vieillissement cutané, provenant du phénomène de glycation. Une telle composition peut prendre en poids: de 70.0 à 90.0% d'eau déminéralisée, de 6.0 à 10.0 % de mélange de caprilic/capric acid triglyceride, de 3.0 à 12.0 % de glycérine, de 2.0 à 5.0 % de squalane, ainsi que l'addition de 2 à 10 % dans la composition finale d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin D'autres actifs pourront complémenter la composition, tels qu'un parfum ne contenant pas d'allergène (au sens du Règlement Cosmétique n°1223/2009, liste des 26 substances allergènes les plus connues), des Oligo-éléments ou encore des Acides de fruits. La demande concerne aussi un tube-préci-dose, en PE blanc, qui permet de protéger la composition, mais également de favoriser une application optimale et précise, en quantité (g/cm2 de peau) du produit. En effet, afin d'obtenir le meilleur résultat cutané, il est indispensable que le produit soit appliqué à raison de 1,43mg/cm2 à 1,90mg/cm2 de peau.A composition is described for topical application, intended to moisturize the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation. Such a composition may take by weight: 70.0 to 90.0% demineralized water, 6.0 to 10.0% caprilic/capric acid triglyceride mixture, 3.0 to 12.0% glycerin, 2.0 to 5.0% squalane, as well as the addition of 2 to 10% in the final composition of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid ( and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin Other active ingredients may complement the composition, such as a fragrance that does not contain an allergen (as defined in Cosmetics Regulation No. 1223/2009, list of the 26 most allergenic substances better known), trace elements or even fruit acids. The request also concerns a precise-dose tube, in white PE, which makes it possible to protect the composition, but also to promote optimal and precise application, in quantity (g/cm2 of skin) of the product. Indeed, in order to obtain the best skin result, it is essential that the product be applied at a rate of 1.43mg/cm2 to 1.90mg/cm2 of skin.

Description

[0001] Cette composition permet de remédier aux principaux inconvénients présentés par les composition cosmétiques connues, à savoir une efficacité limitée du fait de l'absence de prise en charge de ce phénomène dégradatif spécifique. En effet, la glycation à des conséquences dans tout l'organisme, et joue notamment un rôle important dans la genèse de certaines maladies en provoquant, par exemple, des lésions cellulaires, tissulaires, et vasculaires. Ceci est particulièrement visible au niveau cutané. La présente invention se présente en flacon en PE blanc, préci-dose, afin de favoriser une application précise, en quantité du produit/cm2 de peau [0001] This composition makes it possible to overcome the main drawbacks exhibited by known cosmetic compositions, namely a limited effectiveness due to the absence of management of this specific degradative phenomenon. Indeed, glycation has consequences throughout the body, and in particular plays an important role in the genesis of certain diseases by causing, for example, cell, tissue and vascular lesions. This is particularly visible on the skin. The present invention is presented in a white PE bottle, preci-dose, in order to promote precise application, in quantity of the product/cm2 of skin

[0002] A cet effet, la composition suivant l'invention comprend au moins, de l'eau déminéralisée, un mélange de caprilic/capric acid triglyceride, de la glycérine, du squalane, ainsi que l'addition dans la composition finale d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin For this purpose, the composition according to the invention comprises at least demineralized water, a mixture of caprilic / capric acid triglyceride, glycerin, squalane, as well as the addition in the final composition of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin

[0003] Suivant une forme de réalisation de l'invention, l'eau déminéralisée est une eau de qualité cosmétique. [0003] According to one embodiment of the invention, the demineralized water is cosmetic quality water.

[0004] Suivant une forme de réalisation de l'invention, le mélange de caprilic/capric acid triglycéride provient de l'huile de noix de coco According to one embodiment of the invention, the mixture of caprilic / capric acid triglyceride comes from coconut oil

[0005] Suivant une forme de réalisation avantageuse, la glycérine est une glycérine d'origine végétale [0005] According to an advantageous embodiment, the glycerin is a glycerin of plant origin

[0006] Suivant une forme de réalisation de l'invention, le squalane est un dérivé d'huile d'olive [0006] According to one embodiment of the invention, the squalane is a derivative of olive oil

[0007] Suivant une forme de réalisation avantageuse, le produit contient de plus un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin According to an advantageous embodiment, the product also contains a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin

[0008] Suivant un avantage de l'invention, la composition comprend, en volume : de 70.0 à 90.0 % d'eau déminéralisée, de 6.0 à 10.0 % de mélange de caprilic/capric acid triglyceride, de 3.0 à 12.0 % de glycérine, de 2.0 à 5.0 % de squalane, ainsi que l'addition de 2.0 à 10.0 % dans la composition finale d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin According to an advantage of the invention, the composition comprises, by volume: from 70.0 to 90.0% demineralized water, from 6.0 to 10.0% of caprilic/capric acid triglyceride mixture, from 3.0 to 12.0% of glycerin, from 2.0 to 5.0% of squalane, as well as the addition of 2.0 to 10.0% in the final composition of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin

[0009] D'autres détails et particularités de l'invention ressortiront de la description ci-après, à titre d'exemples non-limitatifs, de compositions destinées à améliorer l'état de la peau des diabétiques. Other details and particularities of the invention will emerge from the description below, by way of non-limiting examples, of compositions intended to improve the condition of the skin of diabetics.

[0010] La composition susdite peut également contenir un gluconate de magnésium ou de calcium améliorant son efficacité, introduit dans la composition à raison de 0.001% à 0.01% en poids. The aforesaid composition may also contain a magnesium or calcium gluconate improving its effectiveness, introduced into the composition at a rate of 0.001% to 0.01% by weight.

[0011] La composition susdite peut également contenir en plus de 0.01% à 0.10% en poids d'acide malique ou d'acide lactique [0011] The aforesaid composition may also contain more than 0.01% to 0.10% by weight of malic acid or lactic acid

[0012] La composition susdite peut également contenir un parfum naturel améliorant son odeur, ce parfum, introduit dans la composition à raison de 0.10 % à 0.50% en poids, étant choisi parmi les parfums neutres par rapport aux constituants susdits, et ne contenant pas d'allergènes (au sens du Règlement Cosmétique n°1223/2009, liste des 26 substances allergènes les plus connues) The aforesaid composition may also contain a natural perfume which improves its smell, this perfume, introduced into the composition at the rate of 0.10% to 0.50% by weight, being chosen from neutral perfumes with respect to the aforementioned constituents, and not containing allergens (as defined in Cosmetics Regulation No. 1223/2009, list of the 26 most well-known allergenic substances)

[0013] On a obtenu d'excellents résultats sur l'amélioration de l'état de la peau du diabétique, et en particulier des résultats durables, avec une composition comprenant en poids: 67,95% d'eau déminéralisée, 8% de mélange de caprilic/capric acid triglyceride, 6% de glycérine, 2% de squalane, ainsi que l'addition dans la composition finale de 3% d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin [0013] Excellent results have been obtained in improving the condition of the diabetic's skin, and in particular lasting results, with a composition comprising by weight: 67.95% demineralized water, 8% mixture of caprilic/capric acid triglyceride, 6% glycerin, 2% squalane, as well as the addition in the final composition of 3% of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients) : Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin

[0014] De plus, afin d'obtenir le meilleur résultat cutané, il est indispensable que le produit soit appliqué à raison de 1,43mg/cm2 à 1,90mg/cm2 de surface de peau. [0014] Furthermore, in order to obtain the best result for the skin, it is essential that the product be applied at a rate of 1.43 mg/cm2 to 1.90 mg/cm2 of skin surface.

Claims (13)

1. Composition pour application topique, à visée hydratante pour la peau du diabétique, dans le but de favoriser une diminution de la perte d'hydratation et du vieillissement cutané, provenant du phénomène de glycation. Cette composition contient de 70.0 à 90.0% d'eau déminéralisée, de 6,0 à 10.0% de mélange de caprilic/capric acid triglyceride, de 3.0 à 12.0% de glycérine, de 2.0 à 5.0% de squalane, ainsi que l'addition de 2.0 à 10.0% dans la composition finale d'un mélange répon dant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin1. Composition for topical application, intended to moisturize the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging resulting from the phenomenon of glycation. This composition contains 70.0 to 90.0% deionized water, 6.0 to 10.0% caprilic/capric acid triglyceride mixture, 3.0 to 12.0% glycerin, 2.0 to 5.0% squalane, and the addition from 2.0 to 10.0% in the final composition of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin 2. Composition selon la revendication 1, caractérisée en ce que l'eau déminéralisée est une eau de qualité cosmétique.2. Composition according to claim 1, characterized in that the demineralised water is cosmetic quality water. 3. Composition selon la revendication 2, caractérisée en ce que le mélange de caprilic/capric acid triglycéride provient de l'huile de noix de coco.3. Composition according to claim 2, characterized in that the mixture of caprilic/capric acid triglyceride comes from coconut oil. 4. Composition selon la revendication 3, caractérisée en ce que la glycérine est une glycérine d'origine végétale4. Composition according to claim 3, characterized in that the glycerin is a glycerin of plant origin 5. Composition selon la revendication 4, caractérisée en ce que le squalane est un dérivé d'huile d'olive5. Composition according to claim 4, characterized in that the squalane is a derivative of olive oil 6. Composition selon la revendication 5, caractérisée en ce qu'elle contient de plus, de 2 à 10 % dans la composition finale d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin6. Composition according to claim 5, characterized in that it additionally contains from 2 to 10% in the final composition of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua ( and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin 7. Composition selon les revendications 2 à 6, caractérisée en ce qu'elle comprend, en poids : de 70 à 90 % d'eau déminéralisée, de 6,0 à 10 % de mélange de caprilic/capric acid triglyceride, de 3.0 à 12.0 % de glycérine, de 2.0 à 5.0 % de squalane, de de 2 à 10 % dans la composition finale, d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin7. Composition according to claims 2 to 6, characterized in that it comprises, by weight: from 70 to 90% demineralized water, from 6.0 to 10% of caprilic/capric acid triglyceride mixture, from 3.0 to 12.0% of glycerin, from 2.0 to 5.0% of squalane, from 2 to 10% in the final composition, of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin 8. Composition selon la revendication 7, caractérisée en ce qu'elle contient en plus de 0.10% à 0.50% en poids d'un parfum neutre par rapport aux constituants précités.8. Composition according to claim 7, characterized in that it additionally contains 0.10% to 0.50% by weight of a neutral fragrance with respect to the aforementioned constituents. 9. Composition selon la revendication 8, caractérisée en ce qu'elle contient en plus de 0.001% à 0.01% en poids d'un gluconate de magnésium ou de calcium9. Composition according to claim 8, characterized in that it additionally contains 0.001% to 0.01% by weight of a magnesium or calcium gluconate 10. Composition selon la revendication 9, caractérisée en ce qu'elle contient en plus de 0.01% à 0.10 % en poids d'acide malique ou d'acide lactique10. Composition according to claim 9, characterized in that it additionally contains from 0.01% to 0.10% by weight of malic acid or lactic acid 11. Composition selon l'une quelconque des revendications 8 à 10, caractérisée en ce qu'elle comprend, en poids 70.0 à 90.0% d'eau déminéralisée, de 6,0 à 10.0 % de mélange de caprilic/capric acid triglyceride, de 3.0 à 12.0 % de glycérine, de 2.0 à 5.0 % de squalane, ainsi que l'addition de 2.0 à 10.0 % dans la composition finale d'un mélange répondant à la composition suivante selon l'INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin11. Composition according to any one of claims 8 to 10, characterized in that it comprises, by weight 70.0 to 90.0% demineralized water, 6.0 to 10.0% mixture of caprilic / capric acid triglyceride, 3.0 to 12.0% of glycerin, from 2.0 to 5.0% of squalane, as well as the addition of 2.0 to 10.0% in the final composition of a mixture corresponding to the following composition according to the INCI (International Nomenclature of Cosmetics Ingredients): Aqua (and) Citrus Paradisi Fruit and Peel Extract (and) Hydrolyzed Hyaluronic Acid (and) Sodium Hyaluronate (and) Alcohol (and) Maltodextrin 12. Flacon en PE blanc, de type preci-dose, permettant de favoriser une application précise, en quantité du produit/cm2 de peau (de1,43mg/cm2 à 1,90mg/cm2 de peau)12. White PE bottle, of the preci-dose type, to promote precise application, in quantity of product/cm2 of skin (from 1.43mg/cm2 to 1.90mg/cm2 of skin) 13. Flacon selon la revendication 12, caractérisé par le fait qu'il est entièrement hermétique.13. Bottle according to claim 12, characterized in that it is entirely hermetic.
CH70351/21A 2021-10-06 2021-10-06 Composition for topical application, for moisturizing the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation. CH717634A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CH70351/21A CH717634A2 (en) 2021-10-06 2021-10-06 Composition for topical application, for moisturizing the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH70351/21A CH717634A2 (en) 2021-10-06 2021-10-06 Composition for topical application, for moisturizing the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation.

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CH717634A2 true CH717634A2 (en) 2022-01-14

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CH70351/21A CH717634A2 (en) 2021-10-06 2021-10-06 Composition for topical application, for moisturizing the skin of diabetics, with the aim of promoting a reduction in the loss of hydration and skin aging, resulting from the phenomenon of glycation.

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