CH651930A5 - Apparatus for analysis and sorting of particles - Google Patents
Apparatus for analysis and sorting of particles Download PDFInfo
- Publication number
- CH651930A5 CH651930A5 CH1549/83A CH154983A CH651930A5 CH 651930 A5 CH651930 A5 CH 651930A5 CH 1549/83 A CH1549/83 A CH 1549/83A CH 154983 A CH154983 A CH 154983A CH 651930 A5 CH651930 A5 CH 651930A5
- Authority
- CH
- Switzerland
- Prior art keywords
- particles
- particle
- flow
- liquid
- downstream
- Prior art date
Links
- 239000002245 particle Substances 0.000 title claims abstract description 77
- 238000004458 analytical method Methods 0.000 title claims description 11
- 238000001514 detection method Methods 0.000 claims abstract description 34
- 239000007788 liquid Substances 0.000 claims abstract description 30
- 238000005286 illumination Methods 0.000 claims description 7
- 239000012530 fluid Substances 0.000 claims description 6
- 238000011144 upstream manufacturing Methods 0.000 claims description 5
- 230000005855 radiation Effects 0.000 claims 2
- 238000005507 spraying Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 abstract description 8
- 230000003287 optical effect Effects 0.000 description 14
- 239000000725 suspension Substances 0.000 description 6
- 230000005684 electric field Effects 0.000 description 3
- 238000004891 communication Methods 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 238000009652 hydrodynamic focusing Methods 0.000 description 2
- 238000002847 impedance measurement Methods 0.000 description 2
- 238000004513 sizing Methods 0.000 description 2
- PIGCSKVALLVWKU-UHFFFAOYSA-N 2-Aminoacridone Chemical compound C1=CC=C2C(=O)C3=CC(N)=CC=C3NC2=C1 PIGCSKVALLVWKU-UHFFFAOYSA-N 0.000 description 1
- 101000637792 Homo sapiens Solute carrier family 35 member G5 Proteins 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 102100032019 Solute carrier family 35 member G5 Human genes 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- 238000012883 sequential measurement Methods 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
- G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
- G01N15/13—Details pertaining to apertures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1019—Associating Coulter-counter and optical flow cytometer [OFC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N2015/1028—Sorting particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1413—Hydrodynamic focussing
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB08308181A GB2137352B (en) | 1983-03-24 | 1983-03-24 | Particle analyzing and sorting apparatus |
Publications (1)
Publication Number | Publication Date |
---|---|
CH651930A5 true CH651930A5 (en) | 1985-10-15 |
Family
ID=10540165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH1549/83A CH651930A5 (en) | 1983-03-24 | 1983-03-22 | Apparatus for analysis and sorting of particles |
Country Status (7)
Country | Link |
---|---|
AU (1) | AU1279083A (sv) |
CH (1) | CH651930A5 (sv) |
DE (1) | DE3310551C2 (sv) |
FR (1) | FR2543298B1 (sv) |
GB (1) | GB2137352B (sv) |
NL (1) | NL8301045A (sv) |
SE (1) | SE431487B (sv) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2653885B1 (fr) * | 1989-10-27 | 1994-01-14 | Abx | Appareil pour le comptage et la determination d'au moins une sous-population leucocytaire. |
DE19520298A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Sortiervorrichtung für biologische Zellen oder Viren |
JP4323571B2 (ja) | 1997-01-31 | 2009-09-02 | エックスワイ, インコーポレイテッド | 光学装置 |
US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
US6228652B1 (en) * | 1999-02-16 | 2001-05-08 | Coulter International Corp. | Method and apparatus for analyzing cells in a whole blood sample |
US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
CA2822983C (en) | 2000-11-29 | 2017-05-09 | Xy, Llc | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
WO2002075284A2 (en) * | 2001-03-20 | 2002-09-26 | Abb Bomem Inc. | Flow-through cell |
US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
JP4595067B2 (ja) | 2002-08-01 | 2010-12-08 | エックスワイ,エルエルシー | 低圧精子細胞分離システム |
CN100570360C (zh) | 2002-08-15 | 2009-12-16 | Xy公司 | 一种流式细胞仪及流式细胞计数方法 |
US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
DK2305171T3 (da) | 2003-03-28 | 2022-03-21 | Inguran Llc | Apparat og fremgangsmåder til tilvejebringelse af kønssorteret dyresæd |
ES2541121T3 (es) | 2003-05-15 | 2015-07-16 | Xy, Llc | Clasificación eficiente de células haploides por sistemas de citometría de flujo |
US7892725B2 (en) | 2004-03-29 | 2011-02-22 | Inguran, Llc | Process for storing a sperm dispersion |
AU2005266930B2 (en) | 2004-07-22 | 2010-09-16 | Inguran, Llc | Process for enriching a population of sperm cells |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
US3826364A (en) * | 1972-05-22 | 1974-07-30 | Univ Leland Stanford Junior | Particle sorting method and apparatus |
DE2632962C3 (de) * | 1976-07-22 | 1980-08-21 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen | Partikelseparator |
DE2712360A1 (de) * | 1977-03-22 | 1978-09-28 | Zoeld Tibor Dr Phys | Kanalzaehler zur zaehlung und groessenbestimmung von in einem elektrolyten suspendierten teilchen |
DE2750447C2 (de) * | 1977-11-11 | 1986-04-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Vorrichtung zur Messung bestimmter Eigenschaften in einer Partikelsuspension suspendierter Partikel |
DE2943116C2 (de) * | 1979-10-25 | 1986-06-19 | Gesellschaft für Strahlen- und Umweltforschung mbH, 8000 München | Einrichtung zur durchflußcytometrischen Reaktions- und/oder Diffusionsmessung |
-
1983
- 1983-03-22 CH CH1549/83A patent/CH651930A5/fr not_active IP Right Cessation
- 1983-03-23 DE DE3310551A patent/DE3310551C2/de not_active Expired - Fee Related
- 1983-03-24 FR FR8304872A patent/FR2543298B1/fr not_active Expired
- 1983-03-24 AU AU12790/83A patent/AU1279083A/en not_active Abandoned
- 1983-03-24 SE SE8301630A patent/SE431487B/sv not_active IP Right Cessation
- 1983-03-24 GB GB08308181A patent/GB2137352B/en not_active Expired
- 1983-03-24 NL NL8301045A patent/NL8301045A/nl not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB8308181D0 (en) | 1983-05-05 |
GB2137352A (en) | 1984-10-03 |
GB2137352B (en) | 1986-10-15 |
DE3310551C2 (de) | 1994-07-28 |
DE3310551A1 (de) | 1984-09-27 |
SE8301630L (sv) | 1984-02-06 |
AU1279083A (en) | 1984-09-27 |
SE431487B (sv) | 1984-02-06 |
FR2543298B1 (fr) | 1985-08-09 |
FR2543298A1 (fr) | 1984-09-28 |
SE8301630D0 (sv) | 1983-03-24 |
NL8301045A (nl) | 1984-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |