CH637370A5 - Racemic forms and optically active forms of 2-(4-biphenylyl)-N-(diethylaminoalkyl)-propionamide, salts thereof and relative preparation processes - Google Patents

Racemic forms and optically active forms of 2-(4-biphenylyl)-N-(diethylaminoalkyl)-propionamide, salts thereof and relative preparation processes Download PDF

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Publication number
CH637370A5
CH637370A5 CH1216178A CH1216178A CH637370A5 CH 637370 A5 CH637370 A5 CH 637370A5 CH 1216178 A CH1216178 A CH 1216178A CH 1216178 A CH1216178 A CH 1216178A CH 637370 A5 CH637370 A5 CH 637370A5
Authority
CH
Switzerland
Prior art keywords
propionamide
bromide
iodide
compound according
ethyl
Prior art date
Application number
CH1216178A
Other languages
English (en)
Italian (it)
Inventor
Vittorio Pestellini
Mario Ghelardoni
Claudio Bianchini
Piero Del Soldato
Giovanna Volterra
Alberto Meli
Original Assignee
Menarini Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Sas filed Critical Menarini Sas
Publication of CH637370A5 publication Critical patent/CH637370A5/it

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH1216178A 1977-11-30 1978-11-28 Racemic forms and optically active forms of 2-(4-biphenylyl)-N-(diethylaminoalkyl)-propionamide, salts thereof and relative preparation processes CH637370A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT964377A IT1090782B (it) 1977-11-30 1977-11-30 2 4 bifenilil 2 dietilamino alchil propionamide suoi sali e procedimenti di fabbricazione relativi

Publications (1)

Publication Number Publication Date
CH637370A5 true CH637370A5 (en) 1983-07-29

Family

ID=11132874

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1216178A CH637370A5 (en) 1977-11-30 1978-11-28 Racemic forms and optically active forms of 2-(4-biphenylyl)-N-(diethylaminoalkyl)-propionamide, salts thereof and relative preparation processes

Country Status (9)

Country Link
JP (1) JPS5490157A (pt)
BE (1) BE872403A (pt)
CA (1) CA1118446A (pt)
CH (1) CH637370A5 (pt)
DE (1) DE2851416A1 (pt)
ES (1) ES475533A1 (pt)
FR (1) FR2410641A1 (pt)
IT (1) IT1090782B (pt)
NL (1) NL7811698A (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20012025A1 (it) * 2001-09-28 2003-03-28 Dompe Spa Sali di ammonio quaternari di omega-amminoalchilammidi di acidi r 2-aril-propionici e composizioni farmaceutiche che li contengono
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
ES2559781T3 (es) * 2006-08-08 2016-02-15 Techfields Biochem Co. Ltd Profármacos de ácidos aril- y heteroarilacéticos solubles en agua y con carga positiva con una tasa de penetración en piel muy rápida
AU2006347391B2 (en) * 2006-08-15 2013-03-07 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
AU2013206218B2 (en) * 2006-08-15 2016-06-30 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aryl- and heteroarylpropionic acids with very fast skin penetration rate
US9371284B2 (en) 2007-06-04 2016-06-21 Techfields Pharma Co., Ltd. Pro-drugs of NSAIAS with very high skin and membranes penetration rates and their new medicinal uses
KR20230085223A (ko) 2008-12-04 2023-06-13 충시 위 고투과력을 가진 조성물 및 이의 적용
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
JP6290947B2 (ja) * 2016-02-05 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1584547A (pt) * 1968-06-05 1969-12-26
FR1593024A (pt) * 1968-09-18 1970-05-25
FR2119846A1 (en) * 1970-12-28 1972-08-11 Choay Sa N,n-diethylaminoethylamide of para isobutyl phenylacetic - acid - antiinflammatory and analgesic
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds

Also Published As

Publication number Publication date
NL7811698A (nl) 1979-06-01
ES475533A1 (es) 1980-01-16
FR2410641A1 (fr) 1979-06-29
JPS631286B2 (pt) 1988-01-12
JPS5490157A (en) 1979-07-17
CA1118446A (en) 1982-02-16
IT1090782B (it) 1985-06-26
FR2410641B1 (pt) 1983-04-15
DE2851416C2 (pt) 1989-02-23
BE872403A (fr) 1979-03-16
DE2851416A1 (de) 1979-05-31

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