CH635589A5 - Verfahren zur herstellung von azabicycloheptanon-derivaten. - Google Patents

Verfahren zur herstellung von azabicycloheptanon-derivaten. Download PDF

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Publication number
CH635589A5
CH635589A5 CH93777A CH93777A CH635589A5 CH 635589 A5 CH635589 A5 CH 635589A5 CH 93777 A CH93777 A CH 93777A CH 93777 A CH93777 A CH 93777A CH 635589 A5 CH635589 A5 CH 635589A5
Authority
CH
Switzerland
Prior art keywords
formula
compound
radical
preparation
lactam
Prior art date
Application number
CH93777A
Other languages
German (de)
English (en)
Inventor
Eric Hunt
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of CH635589A5 publication Critical patent/CH635589A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CH93777A 1976-01-27 1977-01-26 Verfahren zur herstellung von azabicycloheptanon-derivaten. CH635589A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2976/76A GB1515241A (en) 1976-01-27 1976-01-27 Beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
CH635589A5 true CH635589A5 (de) 1983-04-15

Family

ID=9749578

Family Applications (1)

Application Number Title Priority Date Filing Date
CH93777A CH635589A5 (de) 1976-01-27 1977-01-26 Verfahren zur herstellung von azabicycloheptanon-derivaten.

Country Status (10)

Country Link
US (1) US4093626A (show.php)
JP (1) JPS5291890A (show.php)
BE (1) BE850593A (show.php)
CH (1) CH635589A5 (show.php)
DE (1) DE2702091A1 (show.php)
DK (1) DK31877A (show.php)
FR (1) FR2339615A1 (show.php)
GB (1) GB1515241A (show.php)
NL (1) NL7700818A (show.php)
SE (1) SE7614265L (show.php)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7706242A (nl) * 1976-06-08 1977-12-12 Glaxo Lab Ltd Werkwijze voor de bereiding van clavamderivaten.
US4529734A (en) * 1976-06-08 1985-07-16 Glaxo Laboratories Limited 2-Formyloxymethyl-clavam
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
DE2860640D1 (en) * 1977-07-23 1981-08-06 Beecham Group Ltd Beta-lactam compounds, preparation and use in pharmaceutical compositions and as chemical intermediates
US4275067A (en) * 1977-09-14 1981-06-23 Beecham Group Limited Decarboxyclavulanic acid thio ethers, their preparation and use
US4202819A (en) * 1979-05-04 1980-05-13 Hoffman-La Roche Inc. 2-(3-Alanyl)clavam antibiotic
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
EP0057664A3 (de) * 1981-01-30 1982-11-17 Ciba-Geigy Ag Clavam-Derivate
GB9214603D0 (en) * 1992-07-09 1992-08-19 Taiho Pharmaceutical Co Ltd 4-oxa-1-azabicyclo (3,2,0) heptan-7-one derivatives as antitumor agents
GB9400220D0 (en) * 1994-01-07 1994-03-02 Taiho Pharmaceutical Co Ltd Novel 3-(substituted methyl)-4-oxa-1-azabicycle (3.2.0) heptan-7-one derivatives useful as antitumor agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334095A (en) * 1965-02-16 1967-08-01 Sandoz Ag Novel pyrrolo-oxazines and pyrrolo-oxazoles
NL7402539A (show.php) * 1973-03-13 1974-09-17
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus

Also Published As

Publication number Publication date
FR2339615A1 (fr) 1977-08-26
SE7614265L (sv) 1977-07-28
NL7700818A (nl) 1977-07-29
US4093626A (en) 1978-06-06
DE2702091A1 (de) 1977-07-28
FR2339615B1 (show.php) 1980-12-19
JPS5291890A (en) 1977-08-02
BE850593A (fr) 1977-07-20
DK31877A (da) 1977-07-28
GB1515241A (en) 1978-06-21

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