FR2339615A1 - Antibiotiques a cycle b-lactame - Google Patents

Antibiotiques a cycle b-lactame

Info

Publication number
FR2339615A1
FR2339615A1 FR7701416A FR7701416A FR2339615A1 FR 2339615 A1 FR2339615 A1 FR 2339615A1 FR 7701416 A FR7701416 A FR 7701416A FR 7701416 A FR7701416 A FR 7701416A FR 2339615 A1 FR2339615 A1 FR 2339615A1
Authority
FR
France
Prior art keywords
antibiotics
lactam cycle
lactam
cycle
cycle antibiotics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7701416A
Other languages
English (en)
Other versions
FR2339615B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of FR2339615A1 publication Critical patent/FR2339615A1/fr
Application granted granted Critical
Publication of FR2339615B1 publication Critical patent/FR2339615B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FR7701416A 1976-01-27 1977-01-19 Antibiotiques a cycle b-lactame Granted FR2339615A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2976/76A GB1515241A (en) 1976-01-27 1976-01-27 Beta-lactam antibiotics

Publications (2)

Publication Number Publication Date
FR2339615A1 true FR2339615A1 (fr) 1977-08-26
FR2339615B1 FR2339615B1 (fr) 1980-12-19

Family

ID=9749578

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7701416A Granted FR2339615A1 (fr) 1976-01-27 1977-01-19 Antibiotiques a cycle b-lactame

Country Status (10)

Country Link
US (1) US4093626A (fr)
JP (1) JPS5291890A (fr)
BE (1) BE850593A (fr)
CH (1) CH635589A5 (fr)
DE (1) DE2702091A1 (fr)
DK (1) DK31877A (fr)
FR (1) FR2339615A1 (fr)
GB (1) GB1515241A (fr)
NL (1) NL7700818A (fr)
SE (1) SE7614265L (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4529734A (en) * 1976-06-08 1985-07-16 Glaxo Laboratories Limited 2-Formyloxymethyl-clavam
DE2725690A1 (de) * 1976-06-08 1977-12-22 Glaxo Lab Ltd Neue clavulansaeurederivate, verfahren zu deren herstellung und diese enthaltende zusammensetzungen
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
DE2860640D1 (en) * 1977-07-23 1981-08-06 Beecham Group Ltd Beta-lactam compounds, preparation and use in pharmaceutical compositions and as chemical intermediates
US4275067A (en) * 1977-09-14 1981-06-23 Beecham Group Limited Decarboxyclavulanic acid thio ethers, their preparation and use
US4202819A (en) * 1979-05-04 1980-05-13 Hoffman-La Roche Inc. 2-(3-Alanyl)clavam antibiotic
ZA804670B (en) * 1979-08-03 1981-07-29 Beecham Group Ltd Derivatives of clavulanic acid, a process for their preparation and their use
DE3169452D1 (en) * 1980-12-09 1985-04-25 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
EP0057664A3 (fr) * 1981-01-30 1982-11-17 Ciba-Geigy Ag Dérivés de clavame
GB9214603D0 (en) * 1992-07-09 1992-08-19 Taiho Pharmaceutical Co Ltd 4-oxa-1-azabicyclo (3,2,0) heptan-7-one derivatives as antitumor agents
GB9400220D0 (en) * 1994-01-07 1994-03-02 Taiho Pharmaceutical Co Ltd Novel 3-(substituted methyl)-4-oxa-1-azabicycle (3.2.0) heptan-7-one derivatives useful as antitumor agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3334095A (en) * 1965-02-16 1967-08-01 Sandoz Ag Novel pyrrolo-oxazines and pyrrolo-oxazoles
NL7402539A (fr) * 1973-03-13 1974-09-17
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus

Also Published As

Publication number Publication date
US4093626A (en) 1978-06-06
CH635589A5 (de) 1983-04-15
DE2702091A1 (de) 1977-07-28
DK31877A (da) 1977-07-28
BE850593A (fr) 1977-07-20
NL7700818A (nl) 1977-07-29
FR2339615B1 (fr) 1980-12-19
GB1515241A (en) 1978-06-21
SE7614265L (sv) 1977-07-28
JPS5291890A (en) 1977-08-02

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Legal Events

Date Code Title Description
ST Notification of lapse