BE857781A - Composes antibacteriens a cycle beta-lactame - Google Patents

Composes antibacteriens a cycle beta-lactame

Info

Publication number
BE857781A
BE857781A BE180166A BE180166A BE857781A BE 857781 A BE857781 A BE 857781A BE 180166 A BE180166 A BE 180166A BE 180166 A BE180166 A BE 180166A BE 857781 A BE857781 A BE 857781A
Authority
BE
Belgium
Prior art keywords
beta
antibacterial compounds
lactam antibacterial
lactam
compounds
Prior art date
Application number
BE180166A
Other languages
English (en)
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of BE857781A publication Critical patent/BE857781A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE180166A 1976-08-17 1977-08-12 Composes antibacteriens a cycle beta-lactame BE857781A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB34106/76A GB1531141A (en) 1976-08-17 1976-08-17 Beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
BE857781A true BE857781A (fr) 1978-02-13

Family

ID=10361448

Family Applications (1)

Application Number Title Priority Date Filing Date
BE180166A BE857781A (fr) 1976-08-17 1977-08-12 Composes antibacteriens a cycle beta-lactame

Country Status (19)

Country Link
JP (1) JPS5323995A (fr)
AT (1) AT351678B (fr)
AU (1) AU518375B2 (fr)
BE (1) BE857781A (fr)
CA (1) CA1104139A (fr)
CH (1) CH639664A5 (fr)
DE (1) DE2736482A1 (fr)
DK (1) DK364177A (fr)
ES (1) ES461691A1 (fr)
FI (1) FI772432A (fr)
FR (2) FR2362142A1 (fr)
GB (1) GB1531141A (fr)
IE (1) IE45559B1 (fr)
IL (1) IL52638A (fr)
NL (1) NL7709007A (fr)
NZ (1) NZ184808A (fr)
PT (1) PT66882B (fr)
SE (1) SE7709071A0 (fr)
ZA (1) ZA774703B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002564B1 (fr) * 1977-11-12 1984-06-20 Beecham Group Plc Dérivés de l'acide 7-oxo-1-azabicyclo-(3.2.0)-hept-2-ène-2-carboxylique, leur préparation, compositions pharmaceutiques les contenant et produits intermédiaires
EP0004132A1 (fr) * 1978-03-04 1979-09-19 Beecham Group Plc Esters d'antibiotiques dérivés de béta-lactame, procédé de préparation et compositions pharmaceutiques les contenant et les composés utilisables comme agents antibactériens
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
DE2963580D1 (en) * 1978-08-02 1982-10-21 Beecham Group Plc Beta-lactam antibacterial agents, a process for their preparation and pharmaceutical compositions containing them
US4530791A (en) * 1979-04-16 1985-07-23 Kowa Co., Ltd. β-Lactam antibiotics
EP0024832B1 (fr) * 1979-08-10 1985-03-13 Beecham Group Plc Antibiotiques du type bêta-lactame, leur préparation, compositions pharmaceutiques les contenant et leur préparation
EP0044142A1 (fr) * 1980-07-03 1982-01-20 Beecham Group Plc Procédé de préparation d'antibiotiques bêta-lactame
EP0057565A1 (fr) * 1981-02-04 1982-08-11 Beecham Group Plc Bêta-lactames à activité antibiotique, leur préparation et leur application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH633554A5 (en) * 1975-11-21 1982-12-15 Merck & Co Inc Process for the preparation of novel thienamycin derivatives.

Also Published As

Publication number Publication date
ZA774703B (en) 1978-06-28
FR2362142A1 (fr) 1978-03-17
FR2362142B1 (fr) 1981-11-06
IE45559B1 (en) 1982-09-22
DK364177A (da) 1978-02-18
IL52638A0 (en) 1977-10-31
ES461691A1 (es) 1978-06-01
PT66882A (fr) 1977-09-01
ATA592177A (de) 1979-01-15
AU518375B2 (en) 1981-10-01
FR2405260A1 (fr) 1979-05-04
IL52638A (en) 1980-12-31
NL7709007A (nl) 1978-02-21
JPS5323995A (en) 1978-03-06
PT66882B (fr) 1979-01-24
FI772432A (fi) 1978-02-18
AU2798677A (en) 1979-02-22
AT351678B (de) 1979-08-10
SE7709071L (sv) 1978-02-17
GB1531141A (en) 1978-11-01
NZ184808A (en) 1980-04-28
CA1104139A (fr) 1981-06-30
SE7709071A0 (sv) 1978-02-17
IE45559L (en) 1978-02-17
DE2736482A1 (de) 1978-02-23
FR2405260B1 (fr) 1980-10-31
CH639664A5 (en) 1983-11-30

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: BEECHAM GROUP LTD

Effective date: 19840812