CH626622A5 - - Google Patents

Download PDF

Info

Publication number
CH626622A5
CH626622A5 CH155381A CH155381A CH626622A5 CH 626622 A5 CH626622 A5 CH 626622A5 CH 155381 A CH155381 A CH 155381A CH 155381 A CH155381 A CH 155381A CH 626622 A5 CH626622 A5 CH 626622A5
Authority
CH
Switzerland
Prior art keywords
carbon atoms
dihydro
piperidine
formula
isobenzofuran
Prior art date
Application number
CH155381A
Other languages
German (de)
English (en)
Inventor
Solomon Samuel Klioze
Victor John Bauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH626622A5 publication Critical patent/CH626622A5/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH155381A 1975-04-30 1981-03-06 CH626622A5 (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/573,145 US4024263A (en) 1975-04-30 1975-04-30 1,3-Dihydrospiro[isobenzofuran-1,4'-piperidine]s

Publications (1)

Publication Number Publication Date
CH626622A5 true CH626622A5 (el) 1981-11-30

Family

ID=24290832

Family Applications (2)

Application Number Title Priority Date Filing Date
CH529176A CH626620A5 (el) 1975-04-30 1976-04-27
CH155381A CH626622A5 (el) 1975-04-30 1981-03-06

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH529176A CH626620A5 (el) 1975-04-30 1976-04-27

Country Status (27)

Country Link
US (1) US4024263A (el)
JP (1) JPS51133273A (el)
AT (1) AT362371B (el)
AU (1) AU498793B2 (el)
BE (1) BE841354A (el)
CA (1) CA1067081A (el)
CH (2) CH626620A5 (el)
DE (1) DE2618579A1 (el)
DK (1) DK192076A (el)
EG (1) EG12288A (el)
ES (2) ES447327A1 (el)
FI (1) FI60014C (el)
FR (1) FR2309226A1 (el)
GB (1) GB1548311A (el)
GR (1) GR59332B (el)
HU (1) HU174754B (el)
IE (1) IE42994B1 (el)
IL (1) IL49477A (el)
LU (1) LU74859A1 (el)
NL (1) NL7604352A (el)
NO (1) NO145619C (el)
NZ (1) NZ180719A (el)
OA (1) OA05319A (el)
PH (1) PH12917A (el)
PT (1) PT65057B (el)
SE (3) SE7604941L (el)
ZA (1) ZA762578B (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268515A (en) * 1980-02-04 1981-05-19 Hoechst-Roussel Pharmaceuticals Inc. Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof
US8785634B2 (en) * 2010-04-26 2014-07-22 Merck Sharp & Dohme Corp Spiropiperidine prolylcarboxypeptidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200118A (en) * 1961-10-31 1965-08-10 Geschickter Fund Med Res Spirocyclic hydrazine imides
US3686186A (en) * 1970-10-05 1972-08-22 William J Houlihan Substituted isochroman or phthalan piperidenes
US3745165A (en) * 1970-10-05 1973-07-10 Sandoz Ag Substituted isochroman or phthalan piperidenes
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s

Also Published As

Publication number Publication date
ATA314976A (de) 1980-10-15
IE42994B1 (en) 1980-12-03
JPS51133273A (en) 1976-11-18
NZ180719A (en) 1978-04-03
FR2309226B1 (el) 1978-08-25
PT65057A (fr) 1976-05-01
PH12917A (en) 1979-10-10
PT65057B (fr) 1978-01-03
IL49477A0 (en) 1976-06-30
NO761487L (el) 1976-11-02
ZA762578B (en) 1977-04-27
FI60014B (fi) 1981-07-31
AU1346876A (en) 1977-11-03
BE841354A (fr) 1976-11-03
ES447327A1 (es) 1977-11-01
FI761180A (el) 1976-10-31
CH626620A5 (el) 1981-11-30
IE42994L (en) 1976-10-30
SE8006597L (sv) 1980-09-19
IL49477A (en) 1978-08-31
OA05319A (fr) 1981-02-28
US4024263A (en) 1977-05-17
NO145619B (no) 1982-01-18
AU498793B2 (en) 1979-03-22
FR2309226A1 (fr) 1976-11-26
AT362371B (de) 1981-05-11
CA1067081A (en) 1979-11-27
GB1548311A (en) 1979-07-11
DE2618579A1 (de) 1976-11-18
ES459821A1 (es) 1978-04-01
LU74859A1 (el) 1977-02-08
EG12288A (en) 1981-06-30
SE8006598L (sv) 1980-09-19
GR59332B (en) 1977-12-14
SE7604941L (sv) 1976-10-31
HU174754B (hu) 1980-03-28
NL7604352A (nl) 1976-11-02
DK192076A (da) 1976-10-31
NO145619C (no) 1982-04-28
FI60014C (fi) 1981-11-10

Similar Documents

Publication Publication Date Title
DE2815578C2 (de) Neue pharmazeutische Verwendung von Nimodipin
DE3629060A1 (de) Kombination von positiv inotrop wirkenden dihydropyridinen mit ace-hemmern, sowie ihre verwendung in arzneimitteln
DE2636735A1 (de) 3-phenylspiro eckige klammer auf isobenzofuran-1,4'-piperidin eckige klammer zu sulfenamide und deren derivate
CH626622A5 (el)
EP0770082B1 (de) Dioxo-thiopyrano-pyridin-carbonsäure-derivate und ihre verwendung als arzneimittel
DE3617976A1 (de) 1,4-dihydropyridin, verfahren zu dessen herstellung und dessen verwendung in antithrombotischen medikamenten
AT365592B (de) Verfahren zur herstellung von neuen 1,3-dihydrosprio(isobenzofuran-1,4'-piperidinen) und von deren salzen
DE69617001T2 (de) (2-morpholinylmethyl)benzamid-derivate
EP0330924B1 (de) Verwendung von 1,4-Dihydropyridin-Derivaten in der Behandlung von Alkoholsucht
AT365593B (de) Verfahren zur herstellung von neuen 1,3-dihydrospiro(isobenzofuran-1,4'-piperidinen)
DE2406065A1 (de) Neue isoindolinderivate, ihre herstellung und die zusammensetzungen, die sie enthalten
EP0280290B1 (de) Mittel mit antidepressiver Wirkung
DE2356369C2 (de) Pharmazeutisches Präparat, enthaltend eine oder mehrere Benzodiazepinverbindungen
DE2702359A1 (de) 1,3-dihydro-1'-dimethylphosphinalkyl-3-phenylspiro eckige klammer auf isobenzofuran eckige klammer zu e
DE4313691A1 (de) 2,6-Disubstituierte 4-Chinolyl-dihydropyridine
EP0086980B1 (de) Substituierte Dibenzodiazepinone, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3600596A1 (de) 4-aminoaryldihydropyridinlactone, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE3432974A1 (de) Arzneimittel zur prophylaxe oder therapie der negativen shizophreniesymtome bei menschen
DE69322218T2 (de) Heteroarenylpiperazine, Verfahren zu ihrer Herstellung und ihre Anwendung als Medikamente
DE3706877A1 (de) Cyclohexencarbonsaeureester, verfahren zu ihrer herstellung und ihre verwendung
DE3872593T2 (de) 1-(n-(2-alkylthio-10h-phenothiazin-10-yl)alkyl)-4-benzoylpiperidine, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
EP0002500B1 (de) Aminoalkylthiodibenzthiepine und -derivate, diese Verbindungen zur Verwendung als Arzneimittel, Verfahren und Zwischenprodukte zu ihrer Herstellung
EP0013424A1 (de) Spiro(dibenz(b,f)thiepin-piperidine), Zwischenprodukte zu ihrer Herstellung und sie enthaltende Arzneimittel
DE3919076A1 (de) Mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
DE1795616A1 (de) Benzonaphtyridine

Legal Events

Date Code Title Description
PL Patent ceased