SE8006598L - Forfarande for framstellning av 1,3-dihydrospiro/isobensofuran-1,4'-piperidiner - Google Patents

Forfarande for framstellning av 1,3-dihydrospiro/isobensofuran-1,4'-piperidiner

Info

Publication number
SE8006598L
SE8006598L SE8006598A SE8006598A SE8006598L SE 8006598 L SE8006598 L SE 8006598L SE 8006598 A SE8006598 A SE 8006598A SE 8006598 A SE8006598 A SE 8006598A SE 8006598 L SE8006598 L SE 8006598L
Authority
SE
Sweden
Prior art keywords
dihydrospiro
procedure
preparing
atoms
isobensofuran
Prior art date
Application number
SE8006598A
Other languages
English (en)
Inventor
S S Klioze
V J Bauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE8006598L publication Critical patent/SE8006598L/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Claims (1)

PATENTKRAV Forfarande for framstallning av eye 1,3-dihydrospiro[isobenaofuran-1,4'-piperidin]-er med allmanna formeln ,0 / Picture Picture dar R; Ri och R2 vardera tar den ovan angivna betydelsen, oxideras. dar R betecknar alkyl med 1 - 4 C-sterner eller fenyl med 7-9 C-atomer, Ri betecknar vate, alkoxi med 1 - 3 C-atomer slier en trifluormetylgrupp Oct R2 heteeknar vats, alkoxi med
1 - 3 C-atomer, tree, finer miter tier, kannetecknat avattett N-substitnerat piperidin med den allmanna formeln
SE8006598A 1975-04-30 1980-09-19 Forfarande for framstellning av 1,3-dihydrospiro/isobensofuran-1,4'-piperidiner SE8006598L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/573,145 US4024263A (en) 1975-04-30 1975-04-30 1,3-Dihydrospiro[isobenzofuran-1,4'-piperidine]s

Publications (1)

Publication Number Publication Date
SE8006598L true SE8006598L (sv) 1980-09-19

Family

ID=24290832

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7604941A SE7604941L (sv) 1975-04-30 1976-04-29 1,3-dihydrospiro/isobensofuran-1,4'-piperidin/-er och forfarande for deras framstellning
SE8006598A SE8006598L (sv) 1975-04-30 1980-09-19 Forfarande for framstellning av 1,3-dihydrospiro/isobensofuran-1,4'-piperidiner
SE8006597A SE8006597L (sv) 1975-04-30 1980-09-19 Forfarande for framstellning av 1,3-dihydrospiro/isobensofuran-1,4'-piperidin/er

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7604941A SE7604941L (sv) 1975-04-30 1976-04-29 1,3-dihydrospiro/isobensofuran-1,4'-piperidin/-er och forfarande for deras framstellning

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8006597A SE8006597L (sv) 1975-04-30 1980-09-19 Forfarande for framstellning av 1,3-dihydrospiro/isobensofuran-1,4'-piperidin/er

Country Status (27)

Country Link
US (1) US4024263A (sv)
JP (1) JPS51133273A (sv)
AT (1) AT362371B (sv)
AU (1) AU498793B2 (sv)
BE (1) BE841354A (sv)
CA (1) CA1067081A (sv)
CH (2) CH626620A5 (sv)
DE (1) DE2618579A1 (sv)
DK (1) DK192076A (sv)
EG (1) EG12288A (sv)
ES (2) ES447327A1 (sv)
FI (1) FI60014C (sv)
FR (1) FR2309226A1 (sv)
GB (1) GB1548311A (sv)
GR (1) GR59332B (sv)
HU (1) HU174754B (sv)
IE (1) IE42994B1 (sv)
IL (1) IL49477A (sv)
LU (1) LU74859A1 (sv)
NL (1) NL7604352A (sv)
NO (1) NO145619C (sv)
NZ (1) NZ180719A (sv)
OA (1) OA05319A (sv)
PH (1) PH12917A (sv)
PT (1) PT65057B (sv)
SE (3) SE7604941L (sv)
ZA (1) ZA762578B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268515A (en) * 1980-02-04 1981-05-19 Hoechst-Roussel Pharmaceuticals Inc. Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof
US8785634B2 (en) * 2010-04-26 2014-07-22 Merck Sharp & Dohme Corp Spiropiperidine prolylcarboxypeptidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200118A (en) * 1961-10-31 1965-08-10 Geschickter Fund Med Res Spirocyclic hydrazine imides
US3686186A (en) * 1970-10-05 1972-08-22 William J Houlihan Substituted isochroman or phthalan piperidenes
US3745165A (en) * 1970-10-05 1973-07-10 Sandoz Ag Substituted isochroman or phthalan piperidenes
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s

Also Published As

Publication number Publication date
ATA314976A (de) 1980-10-15
IE42994B1 (en) 1980-12-03
JPS51133273A (en) 1976-11-18
CH626622A5 (sv) 1981-11-30
NZ180719A (en) 1978-04-03
FR2309226B1 (sv) 1978-08-25
PT65057A (fr) 1976-05-01
PH12917A (en) 1979-10-10
PT65057B (fr) 1978-01-03
IL49477A0 (en) 1976-06-30
NO761487L (sv) 1976-11-02
ZA762578B (en) 1977-04-27
FI60014B (fi) 1981-07-31
AU1346876A (en) 1977-11-03
BE841354A (fr) 1976-11-03
ES447327A1 (es) 1977-11-01
FI761180A (sv) 1976-10-31
CH626620A5 (sv) 1981-11-30
IE42994L (en) 1976-10-30
SE8006597L (sv) 1980-09-19
IL49477A (en) 1978-08-31
OA05319A (fr) 1981-02-28
US4024263A (en) 1977-05-17
NO145619B (no) 1982-01-18
AU498793B2 (en) 1979-03-22
FR2309226A1 (fr) 1976-11-26
AT362371B (de) 1981-05-11
CA1067081A (en) 1979-11-27
GB1548311A (en) 1979-07-11
DE2618579A1 (de) 1976-11-18
ES459821A1 (es) 1978-04-01
LU74859A1 (sv) 1977-02-08
EG12288A (en) 1981-06-30
GR59332B (en) 1977-12-14
SE7604941L (sv) 1976-10-31
HU174754B (hu) 1980-03-28
NL7604352A (nl) 1976-11-02
DK192076A (da) 1976-10-31
NO145619C (no) 1982-04-28
FI60014C (fi) 1981-11-10

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