CH626620A5 - - Google Patents

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Publication number
CH626620A5
CH626620A5 CH529176A CH529176A CH626620A5 CH 626620 A5 CH626620 A5 CH 626620A5 CH 529176 A CH529176 A CH 529176A CH 529176 A CH529176 A CH 529176A CH 626620 A5 CH626620 A5 CH 626620A5
Authority
CH
Switzerland
Prior art keywords
piperidine
formula
acid
dihydro
hydrogen
Prior art date
Application number
CH529176A
Other languages
German (de)
English (en)
Inventor
Solomon Samuel Klioze
Victor John Bauer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of CH626620A5 publication Critical patent/CH626620A5/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH529176A 1975-04-30 1976-04-27 CH626620A5 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/573,145 US4024263A (en) 1975-04-30 1975-04-30 1,3-Dihydrospiro[isobenzofuran-1,4'-piperidine]s

Publications (1)

Publication Number Publication Date
CH626620A5 true CH626620A5 (sv) 1981-11-30

Family

ID=24290832

Family Applications (2)

Application Number Title Priority Date Filing Date
CH529176A CH626620A5 (sv) 1975-04-30 1976-04-27
CH155381A CH626622A5 (sv) 1975-04-30 1981-03-06

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH155381A CH626622A5 (sv) 1975-04-30 1981-03-06

Country Status (27)

Country Link
US (1) US4024263A (sv)
JP (1) JPS51133273A (sv)
AT (1) AT362371B (sv)
AU (1) AU498793B2 (sv)
BE (1) BE841354A (sv)
CA (1) CA1067081A (sv)
CH (2) CH626620A5 (sv)
DE (1) DE2618579A1 (sv)
DK (1) DK192076A (sv)
EG (1) EG12288A (sv)
ES (2) ES447327A1 (sv)
FI (1) FI60014C (sv)
FR (1) FR2309226A1 (sv)
GB (1) GB1548311A (sv)
GR (1) GR59332B (sv)
HU (1) HU174754B (sv)
IE (1) IE42994B1 (sv)
IL (1) IL49477A (sv)
LU (1) LU74859A1 (sv)
NL (1) NL7604352A (sv)
NO (1) NO145619C (sv)
NZ (1) NZ180719A (sv)
OA (1) OA05319A (sv)
PH (1) PH12917A (sv)
PT (1) PT65057B (sv)
SE (3) SE7604941L (sv)
ZA (1) ZA762578B (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4268515A (en) * 1980-02-04 1981-05-19 Hoechst-Roussel Pharmaceuticals Inc. Spiro[dihydrobenzofuran-piperidines and-pyrrolidines], pharmaceutical compositions thereof and methods of use thereof
WO2011137024A1 (en) * 2010-04-26 2011-11-03 Merck Sharp & Dohme Corp. Novel spiropiperidine prolylcarboxypeptidase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200118A (en) * 1961-10-31 1965-08-10 Geschickter Fund Med Res Spirocyclic hydrazine imides
US3686186A (en) * 1970-10-05 1972-08-22 William J Houlihan Substituted isochroman or phthalan piperidenes
US3745165A (en) * 1970-10-05 1973-07-10 Sandoz Ag Substituted isochroman or phthalan piperidenes
US3959475A (en) * 1973-12-12 1976-05-25 American Hoechst Corporation Substituted 1,3-dihydrospiro(isobenzofuran)s

Also Published As

Publication number Publication date
NO145619B (no) 1982-01-18
PH12917A (en) 1979-10-10
US4024263A (en) 1977-05-17
DK192076A (da) 1976-10-31
FI60014B (fi) 1981-07-31
AT362371B (de) 1981-05-11
ES459821A1 (es) 1978-04-01
FI60014C (fi) 1981-11-10
ES447327A1 (es) 1977-11-01
FI761180A (sv) 1976-10-31
FR2309226A1 (fr) 1976-11-26
OA05319A (fr) 1981-02-28
FR2309226B1 (sv) 1978-08-25
DE2618579A1 (de) 1976-11-18
IE42994B1 (en) 1980-12-03
IL49477A (en) 1978-08-31
LU74859A1 (sv) 1977-02-08
GR59332B (en) 1977-12-14
CH626622A5 (sv) 1981-11-30
SE8006598L (sv) 1980-09-19
JPS51133273A (en) 1976-11-18
SE7604941L (sv) 1976-10-31
BE841354A (fr) 1976-11-03
AU1346876A (en) 1977-11-03
HU174754B (hu) 1980-03-28
PT65057A (fr) 1976-05-01
NZ180719A (en) 1978-04-03
NO761487L (sv) 1976-11-02
NO145619C (no) 1982-04-28
PT65057B (fr) 1978-01-03
ATA314976A (de) 1980-10-15
ZA762578B (en) 1977-04-27
IL49477A0 (en) 1976-06-30
IE42994L (en) 1976-10-30
SE8006597L (sv) 1980-09-19
CA1067081A (en) 1979-11-27
NL7604352A (nl) 1976-11-02
GB1548311A (en) 1979-07-11
AU498793B2 (en) 1979-03-22
EG12288A (en) 1981-06-30

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PL Patent ceased