CH624124A5 - - Google Patents
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- Publication number
- CH624124A5 CH624124A5 CH769177A CH769177A CH624124A5 CH 624124 A5 CH624124 A5 CH 624124A5 CH 769177 A CH769177 A CH 769177A CH 769177 A CH769177 A CH 769177A CH 624124 A5 CH624124 A5 CH 624124A5
- Authority
- CH
- Switzerland
- Prior art keywords
- isoglutamine
- alanyl
- acid
- benzyl
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7407276A JPS5914038B2 (ja) | 1976-06-23 | 1976-06-23 | 新規ムラミルジペプチド誘導体 |
JP51150328A JPS6033119B2 (ja) | 1976-12-16 | 1976-12-16 | 新規ムラミルジペプチド誘導体 |
JP1112277A JPS5398922A (en) | 1977-02-03 | 1977-02-03 | Novel melamyldipeptide derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
CH624124A5 true CH624124A5 (pl) | 1981-07-15 |
Family
ID=27279285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH769177A CH624124A5 (pl) | 1976-06-23 | 1977-06-23 |
Country Status (9)
Country | Link |
---|---|
US (1) | US4101536A (pl) |
CA (1) | CA1105005A (pl) |
CH (1) | CH624124A5 (pl) |
DE (1) | DE2728324A1 (pl) |
FR (1) | FR2375249A1 (pl) |
GB (1) | GB1563561A (pl) |
NL (1) | NL171063C (pl) |
SE (1) | SE446740B (pl) |
SU (1) | SU793384A3 (pl) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU727647A1 (ru) * | 1977-11-02 | 1980-04-15 | Институт биоорганической химии им.М.М.Шемякина | Гликопептиды,обладающие противоопухолевой активностью и способ их получени |
US4397844A (en) * | 1978-02-24 | 1983-08-09 | Ciba-Geigy Corporation | Antigen derivatives and processes for their preparation |
JPS5543030A (en) * | 1978-09-21 | 1980-03-26 | Dai Ichi Seiyaku Co Ltd | Prophylactic and remedy for microbial infection disease |
US4335111A (en) * | 1978-12-22 | 1982-06-15 | Agence National De Valorisation De La Recherche (Anvar) | Compounds associating peptidyl of aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds |
FR2449697A1 (fr) | 1979-02-20 | 1980-09-19 | Anvar | Nouveaux muramyl-peptides substitues sur un azote peptidique et medicaments les contenant |
JPS55111499A (en) * | 1979-02-21 | 1980-08-28 | Takeda Chem Ind Ltd | Glucosamine derivative and its preparation |
US4391800A (en) * | 1979-04-27 | 1983-07-05 | Merck & Co., Inc. | Immunologically active peptidyl disaccharides and methods of preparation |
FI75578C (fi) * | 1979-07-25 | 1988-07-11 | Ciba Geigy Ag | Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider. |
US4406889A (en) * | 1980-02-15 | 1983-09-27 | Ciba-Geigy Corporation | Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use |
US4340588A (en) * | 1980-03-28 | 1982-07-20 | Research Corporation | Brucellosis vaccine for cattle containing mycolate esters of trehalose |
US4310514A (en) * | 1980-05-05 | 1982-01-12 | Merck & Co., Inc. | Immunologically active dipeptidyl 5-0,6-0-acyl-2-amino-2-deoxy-D-glucofuranose derivatives and methods of preparation |
US4315913A (en) * | 1980-06-09 | 1982-02-16 | Merck & Co. Inc. | Immunologically active dipeptidyl 2-amino-1,2-dideoxy-D-glucose derivatives and methods of preparation |
GR78246B (pl) * | 1981-01-23 | 1984-09-26 | Ciba Geigy Ag | |
JPS5920297A (ja) * | 1982-07-27 | 1984-02-01 | Dai Ichi Seiyaku Co Ltd | ムラミルジペプチド誘導体 |
US4772466A (en) * | 1983-08-22 | 1988-09-20 | Syntex (U.S.A.) Inc. | Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4770874A (en) * | 1983-08-22 | 1988-09-13 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
US4933179A (en) * | 1983-08-22 | 1990-06-12 | Syntex (U.S.A.) Inc. | Feline leukemia virus antigen vaccines |
FR2564096B1 (fr) * | 1984-05-11 | 1988-02-19 | Anvar | Derives lipophiles de muramylpeptides ayant des proprietes d'activation des macrophages, compositions les contenant et procede pour les obtenir |
DK585886A (da) * | 1985-12-24 | 1987-06-25 | Takeda Chemical Industries Ltd | Immunstimulerende middel og anvendelse deraf |
US5554372A (en) * | 1986-09-22 | 1996-09-10 | Emory University | Methods and vaccines comprising surface-active copolymers |
US4895835A (en) * | 1987-11-20 | 1990-01-23 | Nisshin Oil Mills, Ltd. | Muramyl peptide derivatives and use thereof |
US5149529A (en) * | 1988-04-08 | 1992-09-22 | Board Of Trustees Of Leland Chiron Corporation | Compositions and treatment for herpes simplex |
US4950645A (en) * | 1988-07-08 | 1990-08-21 | Immunotherapeutics, Inc. | Composition for macrophage activation |
US5416070A (en) * | 1988-07-08 | 1995-05-16 | Immunotherapeutics, Inc. | Composition for macrophage activation |
DE3840538A1 (de) * | 1988-12-01 | 1990-06-07 | Helopharm Petrik Co Kg | Peptidoglucan-dimere, verfahren zu ihrer herstellung und ihre verwendung als immunmodulatoren |
GB9320820D0 (en) * | 1993-10-08 | 1993-12-01 | Biokine Tech Ltd | Compounds for medicinal use |
US6156319A (en) * | 1994-07-25 | 2000-12-05 | The Trustees Of The University Of Pennsylvania | Soluble herpesvirus glycoprotein complex vaccine |
US6649746B1 (en) | 1999-05-07 | 2003-11-18 | University Of Virginia Patent Foundation | Biological production of stable glutamine, poly-glutamine derivatives in transgenic organisms and their use for therapeutic purposes |
EP1670508B1 (en) | 2003-02-28 | 2012-10-24 | Trustees Of The University Of Pennsylvania | Compositions, methods and kits relating to poxvirus subunit vaccines |
JP2008522951A (ja) * | 2004-07-19 | 2008-07-03 | ベイラー・カレツジ・オブ・メデイシン | サイトカインシグナル伝達調節物質の調節および免疫療法のための応用 |
ES2380481T3 (es) * | 2005-06-08 | 2012-05-14 | Yisheng Biopharma (Singapore) Pte. Ltd. | Sustancias inmunogénicas que comprenden un adyuvante a base de ácido poliinosínico y ácido policitidílico |
US7868159B2 (en) * | 2005-06-23 | 2011-01-11 | Baylor College Of Medicine | Modulation of negative immune regulators and applications for immunotherapy |
US20070166239A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Mucosal immunogenic substances comprising a polyinosinic acid - polycytidilic acid based adjuvant |
US20070166800A1 (en) * | 2006-01-13 | 2007-07-19 | Haixiang Lin | Immunogenic substances comprising a polyinosinic acid-polycytidilic acid based adjuvant |
CN101678082B (zh) | 2007-03-26 | 2013-06-19 | 再生医药有限公司 | 使用cxcl9和抗cxcl9抗体促进骨髓保护和再生的方法 |
US8324369B2 (en) * | 2007-11-30 | 2012-12-04 | Baylor College Of Medicine | Dendritic cell vaccine compositions and uses of same |
US9808504B2 (en) | 2009-09-22 | 2017-11-07 | Yale University | Immunogenic epitopes as targets for universal cancer vaccines |
KR101955365B1 (ko) | 2011-07-12 | 2019-03-07 | 필라델피아 헬스 앤드 에듀케이션 코포레이션 디/비/에이 드렉셀 유니버시티 컬리지 오브 메디슨 | 신규한 클로스트리듐 디피실(Clostridium Difficile) DNA 백신 |
WO2015116178A1 (en) | 2014-01-31 | 2015-08-06 | Thomas Jefferson University | Fusion proteins for modulating regulatory and effector t cells |
US9834610B2 (en) | 2013-01-31 | 2017-12-05 | Thomas Jefferson University | Fusion proteins for modulating regulatory and effector T cells |
WO2016138286A1 (en) | 2015-02-26 | 2016-09-01 | Stc.Unm | Irgm and precision autophagy controls for antimicrobial and inflammatory disease states and methods of detection of autophagy |
WO2020140007A1 (en) | 2018-12-28 | 2020-07-02 | University Of Rochester | Gene therapy for best1 dominant mutations |
-
1977
- 1977-06-21 GB GB25942/77A patent/GB1563561A/en not_active Expired
- 1977-06-22 SE SE7707276A patent/SE446740B/xx not_active IP Right Cessation
- 1977-06-22 SU SU772497271A patent/SU793384A3/ru active
- 1977-06-23 CH CH769177A patent/CH624124A5/fr not_active IP Right Cessation
- 1977-06-23 FR FR7719306A patent/FR2375249A1/fr active Granted
- 1977-06-23 DE DE19772728324 patent/DE2728324A1/de active Granted
- 1977-06-23 CA CA000281215A patent/CA1105005A/en not_active Expired
- 1977-06-23 US US05/809,245 patent/US4101536A/en not_active Expired - Lifetime
- 1977-06-23 NL NLAANVRAGE7706948,A patent/NL171063C/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SU793384A3 (ru) | 1980-12-30 |
DE2728324A1 (de) | 1978-01-12 |
SE7707276L (sv) | 1978-02-10 |
NL7706948A (nl) | 1977-12-28 |
GB1563561A (en) | 1980-03-26 |
DE2728324C2 (pl) | 1988-07-07 |
NL171063B (nl) | 1982-09-01 |
CA1105005A (en) | 1981-07-14 |
NL171063C (nl) | 1983-02-01 |
FR2375249B1 (pl) | 1980-04-11 |
FR2375249A1 (fr) | 1978-07-21 |
SE446740B (sv) | 1986-10-06 |
US4101536A (en) | 1978-07-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |