CH618980A5 - - Google Patents

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Publication number
CH618980A5
CH618980A5 CH1437375A CH1437375A CH618980A5 CH 618980 A5 CH618980 A5 CH 618980A5 CH 1437375 A CH1437375 A CH 1437375A CH 1437375 A CH1437375 A CH 1437375A CH 618980 A5 CH618980 A5 CH 618980A5
Authority
CH
Switzerland
Prior art keywords
compound
formula
carbon atoms
alkyl
hydrogen
Prior art date
Application number
CH1437375A
Other languages
German (de)
English (en)
Inventor
Warren Neil Beverning
Richard Anthony Partyka
Thomas Andrew Jenks
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH618980A5 publication Critical patent/CH618980A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CH1437375A 1974-11-06 1975-11-06 CH618980A5 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/521,304 US3983119A (en) 1974-11-06 1974-11-06 Process for the preparation of optionally substituted 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones

Publications (1)

Publication Number Publication Date
CH618980A5 true CH618980A5 (no) 1980-08-29

Family

ID=24076219

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1437375A CH618980A5 (no) 1974-11-06 1975-11-06

Country Status (9)

Country Link
US (1) US3983119A (no)
JP (1) JPS5170797A (no)
CA (1) CA1055024A (no)
CH (1) CH618980A5 (no)
DK (1) DK490775A (no)
HU (1) HU175048B (no)
NL (1) NL7512965A (no)
SE (1) SE7512341L (no)
YU (2) YU40802B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7807507A (nl) * 1977-07-25 1979-01-29 Hoffmann La Roche Tricyclische verbindingen.
US4208521A (en) * 1978-07-31 1980-06-17 Bristol-Myers Company Process for the preparation of imidazo[2,1-b]quinazolinones
JPS604186A (ja) * 1983-06-21 1985-01-10 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン化合物
JPS6028979A (ja) * 1983-07-14 1985-02-14 Dai Ichi Seiyaku Co Ltd イミダゾキナゾリン類化合物
US4645836A (en) * 1983-09-12 1987-02-24 Ortho Pharmaceutical Corporation Process for the preparation of 6,7-dihydroxy-4-alkyl-2(1H) quinazolinone-1-propionic acids
IL74349A (en) * 1984-02-15 1988-07-31 Syntex Inc (2-oxo-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolinyl)-oxyalkylamides,their preparation and pharmaceutical compositions containing them
US4783467A (en) * 1985-06-05 1988-11-08 Pfizer Inc. Tetrahydroimidazoquinazolinone inotropic agents
US4837239A (en) * 1985-08-23 1989-06-06 Syntex (U.S.A.) Inc. Cardiotonic phosphodiesterase inhibitors complexed with water soluble vitamins
CN1738623A (zh) * 2003-01-23 2006-02-22 夏尔控股公司 治疗血小板增多症的制剂和方法
US7700608B2 (en) * 2004-08-04 2010-04-20 Shire Holdings Ag Quinazoline derivatives and their use in the treatment of thrombocythemia
US20060030574A1 (en) * 2004-08-04 2006-02-09 Shire Holdings Ag Quinazoline derivatives useful for the treatment of peripheral arterial disease and as phosphodiesterase inhibitors
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
GB0808953D0 (en) * 2008-05-16 2008-06-25 Shire Llc substituted quinazolines
GB0808944D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808950D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substituted quinazolines
GB0808967D0 (en) * 2008-05-16 2008-06-25 Shire Llc Substitute quinazolines

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3257401A (en) * 1964-06-18 1966-06-21 Searle & Co 5-hydroxy-2-methylcycloalkyl[d] imidazo[1, 2-a]pyrimidines
US3600390A (en) * 1968-07-01 1971-08-17 Schering Corp Novel 5-phenyl imidazolidino(5,1-a)5h-quinazolines and process therefor
US3745216A (en) * 1969-12-18 1973-07-10 Smith Kline French Lab Compositions and methods for producing hypotensive activity with imidazo and pyrimido(2,1-b)quinazoline compounds
BE760013A (fr) * 1969-12-18 1971-06-08 Smith Kline French Lab Imidazo et pyrimido -(2,1-b)quinazolines, leurs procedes de preparationet compositions pharmaceutiques en contenant
US3790576A (en) * 1972-03-20 1974-02-05 Parke Davis & Co 9 substituted 4,9-dihydro-1,3,4,4-tetraalkyl-1h-pyrazolo(3,4-b)quinolines
US3859289A (en) * 1973-01-26 1975-01-07 Goetz E Hardtmann Tricyclic pyrimidinones

Also Published As

Publication number Publication date
JPS5170797A (en) 1976-06-18
YU40802B (en) 1986-06-30
YU113482A (en) 1982-10-31
NL7512965A (nl) 1976-05-10
JPS6259109B2 (no) 1987-12-09
US3983119A (en) 1976-09-28
HU175048B (hu) 1980-05-28
DK490775A (da) 1976-05-07
CA1055024A (en) 1979-05-22
YU279875A (en) 1982-10-31
SE7512341L (sv) 1976-05-07

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PL Patent ceased