CH618960A5 - - Google Patents

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Publication number
CH618960A5
CH618960A5 CH101476A CH101476A CH618960A5 CH 618960 A5 CH618960 A5 CH 618960A5 CH 101476 A CH101476 A CH 101476A CH 101476 A CH101476 A CH 101476A CH 618960 A5 CH618960 A5 CH 618960A5
Authority
CH
Switzerland
Prior art keywords
histidyl
tyrosyl
arginyl
valyl
prolyl
Prior art date
Application number
CH101476A
Other languages
German (de)
English (en)
Inventor
Robert Henry Mazur
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of CH618960A5 publication Critical patent/CH618960A5/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/14Angiotensins: Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CH101476A 1975-01-27 1976-01-27 CH618960A5 (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/544,128 US3975365A (en) 1975-01-27 1975-01-27 Inhibitory octapeptides angiotensin II

Publications (1)

Publication Number Publication Date
CH618960A5 true CH618960A5 (ro) 1980-08-29

Family

ID=24170866

Family Applications (1)

Application Number Title Priority Date Filing Date
CH101476A CH618960A5 (ro) 1975-01-27 1976-01-27

Country Status (15)

Country Link
US (1) US3975365A (ro)
JP (1) JPS51100074A (ro)
AT (1) AT357698B (ro)
BE (1) BE837895A (ro)
CA (1) CA1064913A (ro)
CH (1) CH618960A5 (ro)
DE (1) DE2602803A1 (ro)
DK (1) DK29876A (ro)
ES (1) ES444625A1 (ro)
FR (1) FR2298336A1 (ro)
GB (1) GB1537856A (ro)
IE (1) IE42249B1 (ro)
NL (1) NL7600764A (ro)
SE (1) SE7600754L (ro)
ZA (1) ZA76420B (ro)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177133B (en) * 1977-07-18 1981-07-28 Richter Gedeon Vegyeszet Process for preparing angiotensin ii analogues containing alpha- amino-oxy-acid in position 1 with angiotensin ii antagonist activity
ZA794723B (en) * 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
US4356119A (en) * 1978-09-28 1982-10-26 Nordisk Insulinlaboratorium Therapeutically active polypeptides or acid addition salts and a process for producing such compounds
HU181008B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for producing angiotenzin-ii analogues of antagonistic activity containing sarcosyl-group at the 1-positon,and an alpha-hydroxy-carboxylic acid at the 8-position
HU181009B (en) * 1980-01-18 1983-05-30 Richter Gedeon Vegyeszet Process for preparing angiotensin-ii analogues with antagonictic activity containing in position 1 sarcosyl,hydroxyacetyl or l-alpha-aminoxy-propionyl group and in positiona 8 esteric group
US4772684A (en) * 1987-01-20 1988-09-20 Triton Biosciences, Inc. Peptides affecting blood pressure regulation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886134A (en) * 1970-03-09 1975-05-27 Morton Norwich Products Inc Analogues of angiotensin II

Also Published As

Publication number Publication date
CA1064913A (en) 1979-10-23
BE837895A (fr) 1976-07-26
ES444625A1 (es) 1977-05-16
US3975365A (en) 1976-08-17
IE42249L (en) 1976-07-27
DE2602803A1 (de) 1976-07-29
AU1056676A (en) 1977-08-04
NL7600764A (nl) 1976-07-29
GB1537856A (en) 1979-01-04
ATA48976A (de) 1979-12-15
DK29876A (da) 1976-07-28
FR2298336A1 (fr) 1976-08-20
FR2298336B1 (ro) 1979-10-05
ZA76420B (en) 1977-04-27
SE7600754L (sv) 1976-07-28
AT357698B (de) 1980-07-25
JPS51100074A (ro) 1976-09-03
IE42249B1 (en) 1980-07-02

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Legal Events

Date Code Title Description
PL Patent ceased